Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(137 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(18 produits)
- Survivant(14 produits)
- TNF(94 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6231 produits trouvés pour "Apoptose"
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DC661
CAS :DC661 is a palmitoyl-protein thioesterase 1 (PPT1) inhibitor that acts as an anti-lysosomal agent by inhibiting autophagy, demonstrating anti-cancer activity.Formule :C31H39Cl2N5Degré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :552.58Ref: TM-T5538
1mg80,00€2mg105,00€5mg188,00€1mL*10mM (DMSO)230,00€10mg319,00€25mg545,00€50mg780,00€100mg1.074,00€Cobimetinib
CAS :Cobimetinib (GDC-0973) is a MEK1 inhibitor with selective and oral activity. Cobimetinib exhibits antitumor activity. Cost-effective and quality-assured.Formule :C21H21F3IN3O2Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :531.31Ref: TM-T3623
500mgÀ demander1mg38,00€2mg49,00€5mg80,00€10mg90,00€1mL*10mM (DMSO)94,00€25mg170,00€50mg261,00€100mg429,00€Olanzapine HCl
CAS :Olanzapine HCl, an FDA-approved atypical antipsychotic for schizophrenia and bipolar disorder, resembles clozapine and quetiapine.Formule :C17H21ClN4SCouleur et forme :SolidMasse moléculaire :348.89Tomivosertib
CAS :Tomivosertib (eFT508) is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 nM.Formule :C17H20N6O2Degré de pureté :97.34% - 99.72%Couleur et forme :SolidMasse moléculaire :340.38SKF-86002
CAS :SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).Formule :C16H12FN3SDegré de pureté :98% - 99.85%Couleur et forme :SolidMasse moléculaire :297.35VGX-1027
CAS :VGX-1027 (GIT 27) is an isoxazole compound with various immunomodulatory properties.Formule :C11H11NO3Degré de pureté :99.54% - 99.86%Couleur et forme :SolidMasse moléculaire :205.211,4-Naphthoquinone
CAS :1,4-Naphthoquinone used as inhibitor for monoamine oxidase, DNA topoisomerase, and acetyltransferase.Formule :C10H6O2Degré de pureté :99.24% - 99.56%Couleur et forme :SolidMasse moléculaire :158.15GW 5074
CAS :GW 5074 (Raf1 Kinase Inhibitor I)(IC50=9 nM) is an effective and specific c-Raf inhibitor.Formule :C15H8Br2INO2Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :520.94K858 (Racemic)
CAS :K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.Formule :C13H15N3O2SDegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :277.34ELR510444
CAS :ELR510444 (LR510444) is a novel microtubule disruptor; inhibits MDA-MB-231 cell proliferation with IC50 of 30.9 nM.Formule :C19H16N2O2S2Degré de pureté :97.67% - 98.69%Couleur et forme :SolidMasse moléculaire :368.47Apilimod 2HCl
CAS :Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor used in the study of amyotrophic lateral sclerosis.Formule :C23H28Cl2N6O2Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :491.41Enzastaurin HCl
CAS :Enzastaurin (DB-102, LY317615), a synthetic inhibitor of protein kinase C beta, may reduce tumor growth by cutting blood supply.Formule :C32H30ClN5O2Couleur et forme :SolidMasse moléculaire :552.08Tolcapone
CAS :Tolcapone (Ro 40-7592) is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy in combination with levodopaFormule :C14H11NO5Degré de pureté :98.93% - 99.68%Couleur et forme :SolidMasse moléculaire :273.24Ref: TM-T6708
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg82,00€50mg92,00€100mg124,00€200mg170,00€500mg284,00€TAK-243
CAS :TAK-243 (MLN7243) is a selective inhibitor of the ubiquitin-activating enzyme UAE (IC50=1 nM).Formule :C19H20F3N5O5S2Degré de pureté :98.09% - 98.93%Couleur et forme :SolidMasse moléculaire :519.52Ref: TM-T16974
1mg46,00€2mg60,00€5mg90,00€1mL*10mM (DMSO)102,00€10mg142,00€25mg254,00€50mg434,00€100mg623,00€Didymin
CAS :Didymin, an antioxidant, may treat neuroblastoma and neurodegeneration by blocking N-Myc and boosting RKIP.Formule :C28H34O14Degré de pureté :99.12% - 99.87%Couleur et forme :Faintly Beige PowderMasse moléculaire :594.56Avotaciclib sulfate
CAS :Avotaciclib sulfate is a cyclin-dependent kinase inhibitor and antineoplastic.Formule :C13H13N7O5SCouleur et forme :SolidMasse moléculaire :379.35SCR7 pyrazine
CAS :SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Formule :C18H12N4OSDegré de pureté :98.72% - 99.85%Couleur et forme :SolidMasse moléculaire :332.38Ref: TM-T1724
1mg39,00€2mg50,00€5mg79,00€1mL*10mM (DMSO)79,00€10mg120,00€25mg258,00€50mg408,00€100mg588,00€GSK2256098
CAS :GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor.Formule :C20H23ClN6O2Degré de pureté :99.46% - 99.74%Couleur et forme :SolidMasse moléculaire :414.89Ref: TM-T2281
1mg44,00€2mg57,00€5mg84,00€1mL*10mM (DMSO)84,00€10mg130,00€25mg249,00€50mg424,00€100mg625,00€500mg1.314,00€3,6-Dihydroxyflavone
CAS :3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.Formule :C15H10O4Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :254.24Oxfenicine
CAS :Oxfenicine, a 4-Hydroxy-L-phenylglycine, inhibits CPT-1, boosts glucose tolerance & insulin sensitivity in obese, insulin-resistant mice.Formule :C8H9NO3Degré de pureté :99.22%Couleur et forme :White SolidMasse moléculaire :167.16PP1
CAS :PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Formule :C16H19N5Degré de pureté :99% - 99.88%Couleur et forme :Off-White To Grey SolidMasse moléculaire :281.36Ref: TM-T6196
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)89,00€10mg112,00€25mg190,00€50mg268,00€100mg421,00€500mg945,00€Penicillic acid
CAS :Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.Formule :C8H10O4Degré de pureté :98%Couleur et forme :Needles From Petroleum Ether Slight Yellow PowderMasse moléculaire :170.16Thonningianin A
CAS :Thonningianin A: an anti-cancer compound with antioxidant effects, GST inhibitor, and radical scavenger.Formule :C42H34O21Degré de pureté :98.37% - 99.94%Couleur et forme :SolidMasse moléculaire :874.71Ref: TM-T3S0218
1mg52,00€2mg67,00€5mg97,00€10mg160,00€1mL*10mM (DMSO)169,00€25mg263,00€50mg378,00€100mg568,00€Capmatinib
CAS :Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.Formule :C23H17FN6ODegré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :412.42Ref: TM-T1963
5mg48,00€1mL*10mM (DMSO)50,00€10mg63,00€25mg78,00€50mg90,00€100mg124,00€200mg158,00€500mg255,00€Amifostine sodium
CAS :Amifostine sodium is a phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.Formule :C5H15N2NaO3PSCouleur et forme :SolidMasse moléculaire :237.21Betulinic acid
CAS :Betulinic acid, a lupane-type triterpene from white birch bark, has antiretroviral, antimalarial, anti-inflammatory, and anticancer properties.Formule :C30H48O3Degré de pureté :98.22% - 99.7%Couleur et forme :White Crystalline PowderMasse moléculaire :456.70Dinoprost methoxyamine
CAS :Dinoprost methoxyamine is a hormone.Formule :C21H39NO6Couleur et forme :SolidMasse moléculaire :401.544Vistusertib
CAS :Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.Formule :C25H30N6O3Degré de pureté :97.08% - 99.06%Couleur et forme :SolidMasse moléculaire :462.54Ref: TM-T1961
1mg34,00€5mg71,00€1mL*10mM (DMSO)79,00€10mg111,00€25mg170,00€50mg225,00€100mg358,00€200mg530,00€C188-9
CAS :C188-9 (TTI-101) is a Stat3 inhibitor with an IC50 of 4-7 μM.Formule :C27H21NO5SDegré de pureté :98.07% - >99.99%Couleur et forme :SolidMasse moléculaire :471.52Ref: TM-T4650
1mg43,00€2mg56,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg116,00€25mg236,00€50mg376,00€100mg562,00€500mg1.198,00€1g1.839,00€XL888
CAS :XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.Formule :C29H37N5O3Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :503.64NADPH tetrasodium salt
CAS :NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety ofFormule :C21H26N7Na4O17P3Degré de pureté :97.15% - >99.99%Couleur et forme :SolidMasse moléculaire :833.35Vandetanib
CAS :Vandetanib (ZD6474) is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.Formule :C22H24BrFN4O2Degré de pureté :99.7% - >99.99%Couleur et forme :White SolidMasse moléculaire :475.35Ref: TM-T1656
10mg50,00€1mL*10mM (DMSO)52,00€25mg65,00€50mg92,00€100mg166,00€200mg224,00€500mg359,00€CP-31398 dihydrochloride
CAS :CP-31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines.Formule :C22H28Cl2N4ODegré de pureté :98.23%Couleur et forme :SolidMasse moléculaire :435.4ABT-737
CAS :ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.Formule :C42H45ClN6O5S2Degré de pureté :98.15% - >99.99%Couleur et forme :SolidMasse moléculaire :813.43Ref: TM-T2099
2mgÀ demander5mg66,00€1mL*10mM (DMSO)73,00€10mg80,00€25mg130,00€50mg222,00€100mg389,00€PF-4989216
CAS :PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.Formule :C18H13FN6OSDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :380.4Ref: TM-T6938
2mg37,00€5mg62,00€1mL*10mM (DMSO)64,00€10mg96,00€25mg177,00€50mg311,00€100mg376,00€200mg535,00€C25-140
CAS :C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.Formule :C26H31N7ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :457.57Ziyuglycoside II
CAS :1.Formule :C35H56O8Degré de pureté :99.52% - ≥95%Couleur et forme :SolidMasse moléculaire :604.81JX06
CAS :JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.Formule :C10H16N2O2S4Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :324.51Ref: TM-T22350
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg126,00€50mg197,00€100mg318,00€200mg470,00€WT-161
CAS :WT161 is a potent and selective inhibitor of HDAC6 (IC50:0.40 nM).Formule :C27H30N4O3Degré de pureté :95.98% - 98.34%Couleur et forme :SolidMasse moléculaire :458.55MK-2206 dihydrochloride
CAS :MK-2206 dihydrochloride (MK-2206 2HCl) is a variant Akt inhibitor that inhibits Akt1, Akt2, and Akt3 (IC50=8/12/65 nM) with orally active, highly potent andFormule :C25H23Cl2N5ODegré de pureté :99.228% - 99.94%Couleur et forme :SolidMasse moléculaire :480.39Ref: TM-T1952
2mg34,00€5mg49,00€1mL*10mM (DMSO)52,00€10mg66,00€25mg90,00€50mg137,00€100mg205,00€200mg334,00€500mg552,00€4,5-Dicaffeoylquinic acid
CAS :1.Formule :C25H24O12Degré de pureté :98.86% - ≥95%Couleur et forme :SolidMasse moléculaire :516.45Ref: TM-T2S1158
1mg43,00€5mg84,00€1mL*10mM (DMSO)102,00€10mg109,00€25mg172,00€50mg250,00€100mg326,00€200mg522,00€Tauroursodeoxycholate dihydrate
CAS :Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a bile acid that reduces Caspase-3, Caspase-12, ERK, reducing endoplasmic reticulum stress mediated death.Formule :C26H49NO8SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :535.73AZ5576 racemate
CAS :AZ5576 racemate, potent Cdk9 inhibitor, oral, IC50 <5nM; disrupts RNAPII, aids AML treatment, kills MV411 cells.Formule :C21H24FN3O3Couleur et forme :SolidMasse moléculaire :385.43Geranyl acetate
CAS :Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.Formule :C12H20O2Degré de pureté :99.36%Couleur et forme :Physical Description Clear Colorless Liquid With An Odor Of Lavender (Ntp 1992)Masse moléculaire :196.29Isosilybin A
CAS :Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (Formule :C25H22O10Degré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :482.44Pexidartinib
CAS :Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFormule :C20H15ClF3N5Degré de pureté :98.34% - 99.45%Couleur et forme :SolidMasse moléculaire :417.81Ref: TM-T2115
5mg46,00€1mL*10mM (DMSO)49,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€SR-318
CAS :SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Formule :C27H33N5O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :459.58Ref: TM-T12997
2mg35,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg92,00€25mg166,00€50mg259,00€100mg371,00€200mg533,00€CIL56
CAS :CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS).Formule :C23H27N3O5S2Degré de pureté :99.46% - 99.91%Couleur et forme :SolidMasse moléculaire :489.61Ref: TM-T4309
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)81,00€10mg109,00€25mg178,00€50mg284,00€100mg434,00€TPEN
CAS :TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.Formule :C26H28N6Degré de pureté :98% - 99.72%Couleur et forme :White Crystalline PowderMasse moléculaire :424.54Nutlin-3b
CAS :Nutlin-3b, a less potent (+)-enantiomer of Nutlin-3, inhibits p53/MDM2 at IC50: 13.6 μM, 150x weaker than Nutlin-3a.Formule :C30H30Cl2N4O4Degré de pureté :98.83%Couleur et forme :SolidMasse moléculaire :581.492,5-dimethyl Celecoxib
CAS :2,5-dimethyl Celecoxib, a derivative targeting mPGES-1, inhibits PGE2 synthesis in inflammation.Formule :C18H16F3N3O2SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :395.4Lanperisone
CAS :Lanperisone is a muscle relaxant.Formule :C15H18F3NOCouleur et forme :SolidMasse moléculaire :285.3Mitoxantrone
CAS :Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formule :C22H28N4O6Degré de pureté :96.29% - 98.74%Couleur et forme :Blue PowderMasse moléculaire :444.48dl-Maackiain
CAS :1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.Formule :C16H12O5Degré de pureté :97.36% - 99.89%Couleur et forme :SolidMasse moléculaire :284.26AT7519 Hydrochloride
CAS :AT7519 Hydrochloride (AT7519 HCl) is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9.Formule :C16H18Cl3N5O2Degré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :418.71G-749
CAS :G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.Formule :C25H25BrN6O2Degré de pureté :98.32% - 99.60%Couleur et forme :SolidMasse moléculaire :521.41Z-IETD-FMK
CAS :Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.Formule :C30H43FN4O11Degré de pureté :95% - 99.81%Couleur et forme :SolidMasse moléculaire :654.68Aurintricarboxylic acid
CAS :Aurintricarboxylic acid (NSC-4056) blocks nucleases and topoisomerases, stopping nucleic acid binding.Formule :C22H14O9Degré de pureté :97.1%Couleur et forme :Deep Red Coarse Crystalline PowderMasse moléculaire :422.34Obacunone
CAS :Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.Formule :C26H30O7Degré de pureté :98% - ≥95%Couleur et forme :White PowderMasse moléculaire :454.51Ref: TM-T3390
2mg35,00€5mg48,00€1mL*10mM (DMSO)52,00€10mg70,00€25mg104,00€50mg153,00€100mg216,00€200mg320,00€Echinocystic acid
CAS :EA, a natural triterpene, is found in herbs; it has anti-inflammatory and antioxidant properties.Formule :C30H48O4Degré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :472.70Pseudolaric Acid B
CAS :Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Formule :C23H28O8Degré de pureté :98.91% - 99.84%Couleur et forme :SolidMasse moléculaire :432.46Z-YVAD-FMK
CAS :AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formule :C31H39FN4O9Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :630.66GSK481
CAS :GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.Formule :C21H19N3O4Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :377.39GSK963
CAS :GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM).Formule :C14H18N2ODegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :230.31Ref: TM-T5054
1mg34,00€2mg48,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg222,00€50mg358,00€100mg523,00€RET V804M-IN-1
CAS :RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors(IC50 = 20 nM).Formule :C19H16N6ODegré de pureté :97.94% - 99.62%Couleur et forme :SolidMasse moléculaire :344.37Ref: TM-T8467
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg90,00€25mg157,00€50mg236,00€100mg334,00€200mg495,00€NVP-HSP990
CAS :NVP-HSP990 (HSP990) is an effective and specific HSP90α/β inhibitor (IC50: 0.6 /0.8 nM).Formule :C20H18FN5O2Degré de pureté :98.03% - 99.32%Couleur et forme :SolidMasse moléculaire :379.39GSK2982772
CAS :GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Formule :C20H19N5O3Degré de pureté :99.27% - 99.31%Couleur et forme :SolidMasse moléculaire :377.4Ethyl 3,4-dihydroxybenzoate
CAS :Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.Formule :C9H10O4Degré de pureté :99.88%Couleur et forme :White Crystal Or PowderMasse moléculaire :182.17Levistolide A
CAS :1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.Formule :C24H28O4Degré de pureté :98.93% - 99.22%Couleur et forme :SolidMasse moléculaire :380.48Ref: TM-T6S1292
1mg34,00€5mg65,00€1mL*10mM (DMSO)73,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€200mg423,00€LY-364947
CAS :LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.Formule :C17H12N4Degré de pureté :99.65% - 99.96%Couleur et forme :SolidMasse moléculaire :272.3Ref: TM-T2048
5mg62,00€1mL*10mM (DMSO)69,00€10mg78,00€25mg136,00€50mg241,00€100mg354,00€200mg530,00€500mg830,00€Ac-DEVD-AMC
CAS :Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) is the substrate of Caspase-3 .Formule :C30H37N5O13Degré de pureté :98.20%Couleur et forme :White PowderMasse moléculaire :675.64GSK3179106
CAS :GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nMFormule :C22H21F4N3O4Degré de pureté :99.8% - 99.90%Couleur et forme :SolidMasse moléculaire :467.41GSK547
CAS :GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.Formule :C20H18F2N6ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :396.39PF-3758309 hydrochloride
CAS :PF-3758309 hydrochloride (PF-03758309 hydrochloride) , is a PAK4 inhibitor, is also a n orally bioavailable small-molecule inhibitor of p21-activated kinase 4 (Formule :C25H31ClN8OSDegré de pureté :98.83% - >99.99%Couleur et forme :SolidMasse moléculaire :527.08Ref: TM-T4230
1mg42,00€2mg52,00€5mg77,00€1mL*10mM (DMSO)108,00€10mg112,00€25mg172,00€50mg316,00€100mg497,00€Ossirene
CAS :Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.Formule :C2H4Cl3O2Te·H4NDegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :312.05Ref: TM-T6761
2mg39,00€5mg58,00€1mL*10mM (DMSO)66,00€10mg93,00€25mg138,00€50mg197,00€100mg294,00€200mg437,00€Liproxstatin-1
CAS :Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Formule :C19H21ClN4Degré de pureté :97.11% - 99.44%Couleur et forme :SolidMasse moléculaire :340.85Ref: TM-T2376
1mg39,00€5mg85,00€1mL*10mM (DMSO)85,00€10mg130,00€25mg244,00€50mg390,00€100mg495,00€200mg712,00€SZL P1-41
CAS :SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.Formule :C24H24N2O3SDegré de pureté :99.60% - 99.87%Couleur et forme :SolidMasse moléculaire :420.52Garcinol
CAS :Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).Formule :C38H50O6Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :602.8Panobinostat
CAS :Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.Formule :C21H23N3O2Degré de pureté :97.2% - 99.81%Couleur et forme :Yellow SolidMasse moléculaire :349.43Ref: TM-T2383
5mg35,00€1mL*10mM (DMSO)52,00€10mg54,00€25mg82,00€50mg100,00€100mg137,00€200mg168,00€500mg344,00€AS1842856
CAS :AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.Formule :C18H22FN3O3Degré de pureté :99.36% - >99.99%Couleur et forme :SolidMasse moléculaire :347.38Necrostatin 2 racemate
CAS :Necrostatin 2 racemate (Necrostatin-2 racemate) is an potent and specific inhibitor of RIPK1.Formule :C13H12ClN3O2Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :277.71Ref: TM-T7504
1mg62,00€5mg102,00€1mL*10mM (DMSO)133,00€10mg160,00€25mg289,00€50mg500,00€100mg705,00€500mg1.431,00€Pralsetinib
CAS :Pralsetinib (Blu667) (BLU-667) is a highly potent, selective RET inhibitor (IC50s: 0.4, 0.3, 0.4, 0.4, and 0.4 nM for WT RET, RET mutants V804L, V804M, M918TFormule :C27H32FN9O2Degré de pureté :97.88% - 99.8%Couleur et forme :SolidMasse moléculaire :533.6Selpercatinib
CAS :"Selpercatinib (LOXO-292) is a RET tyrosine kinase inhibitor with IC50s of 14.0, 24.1, 530.7 nM for different RET mutations."Formule :C29H31N7O3Degré de pureté :99.89% - >99.99%Couleur et forme :SolidMasse moléculaire :525.6Ref: TM-T8222
2mg34,00€5mg49,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg166,00€50mg259,00€100mg477,00€200mg692,00€500mg1.035,00€BMS-1166
CAS :BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.Formule :C36H33ClN2O7Degré de pureté :99.22%Couleur et forme :SolidMasse moléculaire :641.11Ref: TM-T5697
1mg71,00€5mg146,00€1mL*10mM (DMSO)197,00€10mg213,00€25mg406,00€50mg602,00€100mg893,00€200mg1.198,00€RIPA-56
CAS :RIPA-56 is an inhibitor of RIP1Formule :C13H19NO2Degré de pureté :99.53% - 99.93%Couleur et forme :SolidMasse moléculaire :221.3Ref: TM-T7795
5mg35,00€10mg50,00€1mL*10mM (DMSO)52,00€25mg89,00€50mg129,00€100mg202,00€200mg299,00€500mg504,00€5-Geranoxy-7-methoxycoumarin
CAS :5-Geranoxy-7-methoxycoumarin shows antifungal activity.Formule :C20H24O4Degré de pureté :98.94% - 99.99%Couleur et forme :SolidMasse moléculaire :328.4Ref: TM-TN3110
1mg99,00€5mg231,00€1mL*10mM (DMSO)244,00€10mg343,00€25mg575,00€50mg802,00€100mg1.108,00€Pembrolizumab
CAS :Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.Degré de pureté :95% - 99.70%Couleur et forme :LiquidMasse moléculaire :149 kDaRPI-1
CAS :RPI-1 is a competitive, potent ATP-dependent Ret kinase inhibitor.Formule :C17H15NO4Degré de pureté :98.91% - ≥95%Couleur et forme :SolidMasse moléculaire :297.31Eclitasertib
CAS :Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).Formule :C19H18N6O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :378.38Ref: TM-T9702
1mg101,00€2mg142,00€5mg215,00€1mL*10mM (DMSO)236,00€10mg340,00€25mg618,00€50mg858,00€100mg1.224,00€INH1
CAS :INH1 (IBT13131) is a cell-permeable Hec1 inhibitor that specifically disrupts the Hec1/Nek2 interaction.Formule :C18H16N2OSDegré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :308.4FX1
CAS :FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).Formule :C14H9ClN2O4S2Degré de pureté :97.59%Couleur et forme :SolidMasse moléculaire :368.82Rosiglitazone hydrochloride
CAS :Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Formule :C18H19N3O3S·HClDegré de pureté :99.63% - 99.79%Couleur et forme :SolidMasse moléculaire :393.89BMS-8
CAS :BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.Formule :C27H28BrNO3Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :494.42Ref: TM-T26859
1mg37,00€5mg79,00€1mL*10mM (DMSO)86,00€10mg124,00€25mg222,00€50mg340,00€100mg505,00€200mg705,00€BMS-1001
CAS :BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formule :C35H34N2O7Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :594.7Ref: TM-T8470
1mg58,00€5mg124,00€1mL*10mM (DMSO)172,00€10mg177,00€25mg299,00€50mg424,00€100mg587,00€200mg792,00€Rottlerin
CAS :Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.Formule :C30H28O8Degré de pureté :97.41% - 99.44%Couleur et forme :Orange To Brown PowderMasse moléculaire :516.54HS-1371
CAS :HS-1371 is a novel kinase inhibitor of receptor-interacting protein kinase 3 (RIP3) with an IC50 of 20.8 nM.Formule :C24H24N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.47Metformin
CAS :Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Formule :C4H11N5Degré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :129.16Ref: TM-T8526
10mg44,00€1mL*10mM (DMSO)44,00€25mg66,00€50mg93,00€100mg102,00€500mg250,00€2500mg414,00€Neotame
CAS :Neotame (HSDB 7965), a white dipeptide methyl ester, is a potent non-nutritive sweetener used in many foods.Formule :C20H30N2O5Degré de pureté :99.44%Couleur et forme :White Or Off White Crystalline PowderMasse moléculaire :378.46BBT594
CAS :BBT594 (NVP-BBT594)(NVP-BBT594) is a potent inhibitor of receptor tyrosine kinase RET,Treatment of cancer.Formule :C28H30F3N7O3Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :569.58Belnacasan
CAS :Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.Formule :C24H33ClN4O6Degré de pureté :96.53% - 99.5%Couleur et forme :SolidMasse moléculaire :508.99Ref: TM-T6090
2mg34,00€5mg52,00€1mL*10mM (DMSO)52,00€10mg81,00€25mg161,00€50mg222,00€100mg396,00€200mg585,00€
