Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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GCN2-IN-1
CAS :GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.
Formule :C19H18N10ODegré de pureté :99.49% - 99.64%Couleur et forme :SolidMasse moléculaire :402.41TC-DAPK 6
CAS :TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.Formule :C17H12N2O2Degré de pureté :98.73%Couleur et forme :SolidMasse moléculaire :276.29AOH1160
CAS :AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).Formule :C25H20N2O3Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :396.44CTA 056
CAS :CTA 056 is an ITK inhibitor that inhibits the growth of MOLT-4 xenograft tumors in mice and can be used to study autoimmune disorders.Formule :C35H34N6ODegré de pureté :97.22% - 97.76%Couleur et forme :SolidMasse moléculaire :554.68Triciribine phosphate
CAS :Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.Formule :C13H17N6O7PDegré de pureté :97.94%Couleur et forme :SolidMasse moléculaire :400.28FA16
FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16Formule :C22H27F3N4O2SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :468.54HS38
CAS :HS38: DAPK-specific ATP-competitive inhibitor; Kds: DAPK1 (300 nM), PIM3 (200 nM), ZIPK (280 nM); useful in smooth muscle disorder research.Formule :C14H12ClN5O2SDegré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :349.8Lanperisone HCl
CAS :Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.Formule :C15H19ClF3NODegré de pureté :98.67% - >99.99%Couleur et forme :SolidMasse moléculaire :321.77LDCA
CAS :LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.Formule :C8H5Cl3FNODegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :256.49Imipramine
CAS :Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.Formule :C19H24N2Degré de pureté :99.4%Couleur et forme :White To Off-White /Hydrochloride/ SolidMasse moléculaire :280.41Necrostatin-5
CAS :Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Formule :C19H17N3O2S2Degré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :383.49CSN5i-3
CAS :CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.Formule :C28H29F2N5O2Degré de pureté :99.56% - >99.99%Couleur et forme :SolidMasse moléculaire :505.56Ref: TM-T10895
1mg340,00€5mg732,00€1mL*10mM (DMSO)797,00€10mg1.108,00€25mg1.648,00€50mg2.223,00€100mg2.997,00€CBS9106
CAS :CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.Formule :C18H21ClF3N3O3Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :419.83H2L5186303
CAS :H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.Formule :C26H20N2O8Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :488.45Ref: TM-T22835
2mg44,00€5mg64,00€1mL*10mM (DMSO)75,00€10mg94,00€25mg180,00€50mg283,00€100mg465,00€200mg642,00€KR-33493
CAS :KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.Formule :C20H18BrN3O3SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :460.34RET-IN-23
CAS :RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.Formule :C28H28FN11Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :537.591G244
CAS :1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.Formule :C29H30F2N4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :504.57SPD304 dihydrochloride
CAS :SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.
Formule :C32H34Cl2F3N3O2Degré de pureté :99.25%Couleur et forme :SolidMasse moléculaire :620.53K-8012
CAS :K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.Formule :C23H23FN4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :374.45Ref: TM-T24240
1mg109,00€5mg241,00€1mL*10mM (DMSO)253,00€10mg355,00€25mg532,00€50mg745,00€100mg1.018,00€500mg2.043,00€XX-650-23
CAS :XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).Formule :C18H12N2O2Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :288.3Ref: TM-T24212
1mg44,00€1mL*10mM (DMSO)92,00€5mg96,00€10mg138,00€25mg268,00€50mg447,00€100mg623,00€500mg1.305,00€Antifolate C2
CAS :Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.Formule :C19H21N5O6SDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.46CMLD-2
CAS :CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.Formule :C31H31NO6Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :513.58Ref: TM-T36493
1mg92,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg371,00€25mg608,00€50mg848,00€100mg1.144,00€500mg2.277,00€Deferitazole
CAS :Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.Formule :C18H25NO7SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :399.46P505-15 Acetate
CAS :P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.
Formule :C21H27N9O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :453.5Triparanol
CAS :Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1Formule :C27H32ClNO2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :438Ref: TM-T26296
1mg284,00€5mg645,00€1mL*10mM (DMSO)690,00€10mg867,00€25mg1.283,00€50mg1.700,00€100mg2.347,00€T025
CAS :T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.Formule :C21H18N8Degré de pureté :99.20%Couleur et forme :SolidMasse moléculaire :382.42Ref: TM-T13058
1mg136,00€5mg334,00€1mL*10mM (DMSO)358,00€10mg500,00€25mg807,00€50mg1.099,00€100mg1.485,00€500mg2.962,00€W146
CAS :W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.Formule :C16H27N2O4PDegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :342.37TNIK-IN-3
CAS :TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).Formule :C23H18FN3O2Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :387.41EGFR-IN-11
CAS :EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Formule :C29H35N9O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :573.71A09-003
CAS :A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.Formule :C23H26N4ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :374.48Ciglitazone
CAS :Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.Formule :C18H23NO3SDegré de pureté :98.23% - 99.84%Couleur et forme :White Cyrstalline SolidMasse moléculaire :333.45OR-1896
CAS :OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.Formule :C13H15N3O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :245.28Ref: TM-T12315
1mg89,00€5mg187,00€1mL*10mM (DMSO)207,00€10mg309,00€25mg622,00€50mg982,00€100mg1.333,00€200mg1.783,00€Sabizabulin
CAS :Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.Formule :C21H19N3O4Degré de pureté :98.10% - 99.79%Couleur et forme :SolidMasse moléculaire :377.39Ref: TM-T17228
1mg75,00€2mg99,00€5mg164,00€10mg255,00€25mg487,00€50mg803,00€100mg1.324,00€200mg1.783,00€ZDLD20
CAS :ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.Formule :C22H22N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :386.45DB1976
CAS :DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.Formule :C20H16N8SeDegré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :447.35Anticancer agent 110
CAS :Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cellsFormule :C18H13FN6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.4SYM 2081
CAS :SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.Formule :C6H11NO4Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :161.16GS-9191
CAS :GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , whichFormule :C37H51N8O6PDegré de pureté :98.01 - 99.28%Couleur et forme :SolidMasse moléculaire :734.82AQ4
CAS :AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.Formule :C22H28N4O4Degré de pureté :96.28% - 97.15%Couleur et forme :SolidMasse moléculaire :412.48Sarmustine
CAS :SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.
Formule :C6H11ClN4O3Degré de pureté :98.29% - 99.71%Couleur et forme :SolidMasse moléculaire :222.63HS-276
CAS :HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.Formule :C24H29N5O2Degré de pureté :97.67% - 98.81%Couleur et forme :SolidMasse moléculaire :419.52Ref: TM-T62209
1mg63,00€5mg137,00€1mL*10mM (DMSO)161,00€10mg207,00€25mg408,00€50mg655,00€100mg1.009,00€200mg1.359,00€UK-101
CAS :UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μMFormule :C25H48N2O5SiDegré de pureté :98.97% - 99.08%Couleur et forme :SolidMasse moléculaire :484.74CP 461
CAS :CP 461 is a PDE2A inhibitor that promotes apoptosis in cancer cells without affecting normal cells or COX-1/2.Formule :C25H22ClFN2ODegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :420.91NLRP3/AIM2-IN-3
CAS :NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.Formule :C16H14N2O2Degré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :266.29Ref: TM-T60442
5mg71,00€1mL*10mM (DMSO)78,00€10mg102,00€25mg205,00€50mg334,00€100mg537,00€500mg1.134,00€Pyrazoloacridine
CAS :Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.Formule :C19H21N5O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :367.4iCRT-5
CAS :iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.Formule :C16H17NO5S2Degré de pureté :99.68%Couleur et forme :SolidMasse moléculaire :367.44BCL6-IN-7
CAS :BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.Formule :C18H15ClN6ODegré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :366.8NecroX-7
CAS :NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.Formule :C24H29N3O3SDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :439.57DK419
CAS :DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.Formule :C16H8ClF6N3ODegré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :407.7Epristeride
CAS :Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.Formule :C25H37NO3Degré de pureté :98.12% - >99.99%Couleur et forme :SolidMasse moléculaire :399.57Apostatin-1
CAS :Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.Formule :C19H27N3OSDegré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :345.5Ref: TM-T9079
1mg34,00€2mg49,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg222,00€50mg358,00€100mg530,00€500mg1.153,00€DCG066
CAS :DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.Formule :C30H31F6N3O2Degré de pureté :98.26% - 98.38%Couleur et forme :SolidMasse moléculaire :579.58Ref: TM-T27132
1mg215,00€5mg537,00€1mL*10mM (DMSO)685,00€10mg730,00€25mg1.134,00€50mg1.468,00€100mg1.863,00€200mg2.512,00€eIF4A3-IN-1
CAS :eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.
Formule :C29H23BrClN5O2Degré de pureté :99.49% - 99.89%Couleur et forme :SolidMasse moléculaire :588.88BCP-T.A
CAS :BCP-T.A is an iron death inducer that acts by binding to GPX4.Formule :C23H19Cl2N3OSDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :456.39EM-12
CAS :EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.Formule :C13H12N2O3Degré de pureté :99.34%Couleur et forme :SolidMasse moléculaire :244.25LQZ-7F
CAS :LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.Formule :C14H7N9O3Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :349.26CZL55
CAS :CZL55 is a potent caspase-1 inhibitor with an IC50 value of 0.024 μM.CZL55 has low cytotoxicity and can be used in the study of febrile seizures (FS).Formule :C20H22N2O6Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :386.4F16
CAS :F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.Formule :C16H15IN2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :362.21MBM-55
CAS :MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.Formule :C28H27FN6O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :498.55Ref: TM-T11960
1mg168,00€5mg281,00€1mL*10mM (DMSO)309,00€10mg409,00€25mg627,00€50mg822,00€100mg1.108,00€500mg2.242,00€Mepazine
CAS :Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.Formule :C19H22N2SDegré de pureté :99.88% - 99.92%Couleur et forme :SolidMasse moléculaire :310.46Ref: TM-T16040
500mgÀ demander1mL*10mM (DMSO)35,00€10mg39,00€25mg60,00€50mg93,00€100mg116,00€200mg177,00€CCT018159
CAS :CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.
Formule :C20H20N2O4Degré de pureté :98.78% - 99.79%Couleur et forme :SolidMasse moléculaire :352.38(S)-Enitociclib
CAS :(S)-Enitociclib (VIP152) is a selective CDK9 inhibitor that inhibits the transcription of anti-apoptotic and pro-survival proteins.Formule :C19H18F2N4O2SDegré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :404.43MK-28
CAS :MK-28 is a PERK agonist that reduces toxicity in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.Formule :C24H20N4O2Couleur et forme :SolidMasse moléculaire :396.44Ref: TM-T61859
1mg94,00€5mg222,00€1mL*10mM (DMSO)245,00€10mg356,00€25mg690,00€50mg1.044,00€100mg1.558,00€D609
CAS :D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.Formule :C11H15KOS2Degré de pureté :97.67% - 99.56%Couleur et forme :Off-White PowderMasse moléculaire :266.46SB 699551 dihydrochloride
CAS :SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.Formule :C34H47Cl2N3ODegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :584.66Ref: TM-T23325
1mg50,00€5mg105,00€1mL*10mM (DMSO)142,00€10mg170,00€25mg295,00€50mg424,00€100mg583,00€NSC49652
CAS :NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.Formule :C14H11NO2Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :225.24Ref: TM-T28206
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg113,00€25mg222,00€50mg353,00€100mg530,00€500mg1.153,00€Minodronic acid
CAS :Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.Formule :C9H12N2O7P2Degré de pureté :99.39%Couleur et forme :SolidMasse moléculaire :322.15UC-112
CAS :UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Formule :C22H24N2O2Degré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :348.44Ref: TM-T17195
500mgÀ demander1mg34,00€2mg44,00€5mg70,00€1mL*10mM (DMSO)78,00€10mg99,00€25mg202,00€50mg311,00€100mg445,00€JY-2
CAS :JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.Formule :C13H7Cl2N3ODegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :292.12CUDC-427
CAS :CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.Formule :C29H36N6O4SDegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :564.7Vepafestinib
CAS :Vepafestinib is a RET inhibitor with potential antineoplastic activity[1].Formule :C26H30N6O3Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :474.55Riboxin
CAS :Riboxin (IDP), an orally administered purine derivative known as hypoxanthine riboside, exhibits antihypoxic and antihyperthermic effects.Formule :C10H14N4O11P2Couleur et forme :SolidMasse moléculaire :428.19HDAC-IN-50
CAS :HDAC-IN-50, a potent FGFR/HDAC inhibitor (IC50: 0.18-13 nM), induces apoptosis, cell cycle arrest, and shows anti-tumor activity.Formule :C31H41N7O4Couleur et forme :SolidMasse moléculaire :575.7Mcl-1 inhibitor 13
CAS :Mcl-1 Inhibitor 13 (Example 9), with a Ki of 8.2 nM, serves as an MCL-1 inhibitor suitable for cancer research [1].Formule :C47H45ClFN7O6Couleur et forme :SolidMasse moléculaire :858.35GGTI2417
CAS :GGTI2417 blocks Geranylgeranyltransferase I, targeting RalB for apoptosis and RalA to stop growth.Formule :C24H33N5O4Couleur et forme :SolidMasse moléculaire :455.55Q-VD(OMe)-OPh
CAS :Q-VD-OPh: broad-spectrum, non-toxic caspase inhibitor; cost-effective, specific for apoptotic inhibition.Formule :C27H27F2N3O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :527.52Cu(II)-Elesclomol
CAS :Cu(II)-Elesclomol is a complex formed by the anticancer agent Elesclomol and Cu(II), which has anticancer activity and can be used in the study of leukemia.Formule :C19H18CuN4O2S2Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :462.05SCH79797 dihydrochloride
CAS :SCH79797 dihydrochloride is a PAR1 antagonist with IC50 70 nM, Ki 35 nM, antiproliferative, and pro-apoptotic properties.Formule :C23H27Cl2N5Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :444.4Lepadin E
CAS :Lepadin E, a notably cytotoxic compound, effectively stimulates ferroptosis via the canonical p53-SLC7A11-GPX4 pathway.Formule :C26H47NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.66c-Met/HDAC-IN-3
CAS :c-Met/HDAC-IN-3: dual inhibitor; IC50: c-Met 12.5 nM, HDAC1 26.97 nM; induces apoptosis, G2/M arrest.Formule :C34H35FN4O7Couleur et forme :SolidMasse moléculaire :630.66CHMFL-FLT3-122
CAS :CHMFL-FLT3-122 is a potent and orally available FLT3 kinase inhibitor used to treat FLT3-ITD positive acute myeloid leukemia.
Formule :C26H29N7O2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :471.55UNC3474
CAS :UNC3474, a small molecule ligand, selectively interacts with the aromatic methyl-lysine binding cage of the tumor protein 53BP1 Tudor domain (TT), exhibiting aFormule :C17H28N2OCouleur et forme :SolidMasse moléculaire :276.42MTP
CAS :MTP, a PKM2 inhibitor, promotes apoptosis in cancer cells via caspase-3 activation while also inducing autophagy and enhancing ROS generation.Formule :C29H23F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :516.51SF5
CAS :SF5 is an inhibitor of the apoptosis pathway through JNK-p53-caspase apoptotic cascade.Formule :C15H13NSDegré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :239.34RET-IN-24
CAS :RET-IN-24 (Compound 26) is a selective inhibitor of RET tyrosine kinase, demonstrating antitumor activity [1].Formule :C27H26F2N8OCouleur et forme :SolidMasse moléculaire :516.55ML 10
CAS :ML 10, a [18F] PET radiotracer, detects apoptosis-specific alterations in atherosclerotic plaques.Formule :C9H15FO4Couleur et forme :SolidMasse moléculaire :206.21HJC0152 free base
CAS :HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograftFormule :C15H13Cl2N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :370.19DLC-50
CAS :DLC-50 is a dual inhibitor of PARP-1 and HDAC-1, exhibiting IC50 values of 1.2 nM and 31 nM respectively. It hinders the proliferation of cancer cells such as MDA-MB-436, MDA-MB-231, and MCF-7 with IC50 values of 0.3 μM, 2.7 μM, and 2.41 μM respectively. Additionally, DLC-50 induces apoptosis in MDA-MB-231 cells and causes cell cycle arrest at the G2 phase.Formule :C28H32FN5O4S2Couleur et forme :SolidMasse moléculaire :585.71RIPK2-IN-3
CAS :RIPK2-IN-3 (FCG806791773) is a RIPK2 inhibitor with anti-inflammatory and anticancer activities, useful for research on immune diseases and cancer.Formule :C25H22N4O2Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :410.47PD-1/PD-L1-IN-26
CAS :PD-1/PD-L1-IN-26 is a strong inhibitor with IC50 of 0.0380 μM that may boost immune response in cancer by aiding CD4+ T cell entry to tumors.Formule :C43H52N4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :752.89PD-1/PD-L1-IN-27
CAS :PD-1/PD-L1-IN-27: potent anti-cancer, IC50 134nM, minimal T cell harm, boosts CD8+ T cells, reduces fatigue.Formule :C44H35NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :673.75IK-862
CAS :IK-862 is a selective TACE inhibitor with potential anti-inflammatory and anticancer activity for the study of neuritis.Formule :C25H27N3O4Degré de pureté :97.75% - 98.29%Couleur et forme :SolidMasse moléculaire :433.5YS-363
CAS :YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (Formule :C30H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :494.58RIP1 kinase inhibitor 4
CAS :RIP1 Kinase Inhibitor 4 (Compound 3) is an effective inhibitor of RIP1K, exhibiting an EC50 of ≤ 1000 nM [1].Formule :C23H23N5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :369.46eIF4A3-IN-17
CAS :eIF4A3-IN-17, a silvestrol analogue, disrupts eIF4F assembly; EC50: 0.9-15 nM. Used in cancer pathogenesis research.Formule :C28H25NO7Couleur et forme :SolidMasse moléculaire :487.5INCB3619
CAS :INCB3619 is a selective and potent inhibitor of ADAM with antitumour effects, inhibiting ADAM10, ADAM17, MMP12 and MMP15.Formule :C22H27N3O5Degré de pureté :98.41% - 99.51%Couleur et forme :SolidMasse moléculaire :413.47Tubulin polymerization-IN-56
CAS :Tubulin Polymerization-IN-56 (compound 8l), an indazole derivative, potently inhibits tubulin polymerization by targeting the colchicine site, which inducesFormule :C22H22ClN3O3Couleur et forme :SolidMasse moléculaire :411.882-O-methyl PAF C-16
CAS :2-O-methyl PAF C-16 is a synthetic analog of platelet-activating factor (PAF) featuring a methyl group attached via an ether linkage at the sn-2 position. While the specific biological activities of 2-O-methyl PAF C-16 remain undercharacterized, studies with its C-18 counterpart have demonstrated its ability to modulate various biological processes. These processes include reducing plasma membrane fluidity and hindering the invasiveness of tumor cells in embryonic chick hearts. Furthermore, in rat astrocytes, the C-18 analog prompts the release of significant amounts of nitric oxide (NO) through a mechanism that involves the activation of nitric oxide synthase (NOS).Formule :C25H54NO6PCouleur et forme :SolidMasse moléculaire :495.7TL02-59
CAS :TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Formule :C32H34F3N5O4Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :609.64Ref: TM-T13186
1mg49,00€2mg62,00€5mg93,00€1mL*10mM (DMSO)111,00€10mg133,00€25mg260,00€50mg401,00€100mg557,00€200mg790,00€Z-YVAD-CMK
CAS :Z-YVAD-CMK is an inhibitor of both caspase-1 and caspase-3, as referenced in [1].Formule :C30H37ClN4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :633.09
