Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5592 produits trouvés pour "Apoptose"
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EGFR/BRAFV600E-IN-3
<p>EGFR/BRAFV600E-IN-3 is an inhibitor targeting EGFR, BRAFV600E, and EGFRT790M with IC50 values of 57 nM, 68 nM, and 9.70 nM, respectively.</p>Formule :C25H18N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :422.44PH14
<p>PH14, a dual PI3K/HDAC inhibitor, demonstrates potent inhibition with IC50 values of 20.3 nM for PI3Kα and 24.5 nM for HDAC3.</p>Degré de pureté :98%Couleur et forme :Odour SolidCWI1-2 HCL
CAS :<p>CWI1-2 HCL: Potent IGF2BP2 inhibitor, induces apoptosis/differentiation, targets leukemia therapy.</p>Formule :C22H18Cl4N6O3Degré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :556.23Pamrevlumab
CAS :<p>FG-3019 (Pamrevlumab), a human antibody, targets CTGF, potentially treating idiopathic pulmonary fibrosis.</p>Degré de pureté :100% (SEC-HPLC) - 95%Couleur et forme :LiquidAS-99 TFA
<p>AS-99 TFA: potent ASH1L inhibitor, IC50=0.79 μM, combats leukemia, inhibits cell growth, induces apoptosis.</p>Couleur et forme :SolidThalidomide-O-PEG4-azide
CAS :<p>Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].</p>Formule :C23H29N5O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :519.584-B10
CAS :<p>84-B10 provides protection in cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors.</p>Formule :C25H22F3NO5Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :473.44Aromatase-IN-5
<p>Aromatase-IN-5 (Compound 10) is a potent inhibitor of aromatase with an IC50 value of 0.06 μM. It effectively blocks estrogen production and inhibits the proliferation of breast cancer cell lines such as MCF-7, arresting the cell cycle in the G1 phase and inducing apoptosis. Aromatase-IN-5 shows promise for breast cancer research.</p>Couleur et forme :Odour SolidThalidomide-5,6-Cl
CAS :<p>Thalidomide-5,6-Cl is a cereblon ligand derivative that recruits CRBN protein and forms PROTACs with a linker.</p>Formule :C13H8Cl2N2O4Couleur et forme :SolidMasse moléculaire :327.12P1D-34
<p>P1D-34 is a Pin1 PROTAC degrader with a DC50 value of 177 nM. It downregulates Pin1 substrate proteins, including Cyclin D1, Rb, Mcl-1, Akt, and c-Myc. Additionally, P1D-34 exhibits antiproliferative activity across various acute myeloid leukemia (AML) cell lines and induces DNA damage and apoptosis by generating reactive oxygen species (ROS).</p>Couleur et forme :Odour SolidMEK/PI3K-IN-2
CAS :<p>MEK/PI3K-IN-2 is a potent dual inhibitor (MEK1 IC50: 352 nM, PI3Kα: 107 nM, PI3Kδ: 137 nM) that reduces pAKT, pERK1/2, and hinders tumor cell growth.</p>Formule :C38H41F5IN9O7Couleur et forme :SolidMasse moléculaire :957.688-hydroxy Efavirenz
CAS :<p>8-hydroxy Efavirenz, a main efavirenz metabolite by CYP2B6, causes apoptosis in rat neurons at 0.01 μM.</p>Formule :C14H9ClF3NO3Couleur et forme :SolidMasse moléculaire :331.68Tilogotamab
CAS :<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Degré de pureté :95%Couleur et forme :LiquidBorrelidin
CAS :<p>Borrelidin (Treponemycin) is an inhibitor of trehalose-6-phosphate synthase, a nitrogen-containing macrolide antibiotic isolated from Streptomyces rochei.</p>Formule :C28H43NO6Degré de pureté :98%Couleur et forme :White To Off-White PowderMasse moléculaire :489.64Cyclo(Arg-Gly-Asp-D-Phe-Val) TFA
CAS :<p>Arg-Gly-Asp-D-Phe-Val (TFA) has anti-tumor activity and is an inhibitor of integrin αvβ3.</p>Formule :C28H39F3N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :688.662Moflerafusp alfa
CAS :<p>Moflerafusp alfa is a fusion protein that targets the human signal-regulatory protein alpha (SIRPα) variant V2 D1 domain and human programmed death-ligand 1 (PD-L1). It shows potential for research in various cancer treatments.</p>Couleur et forme :LiquidOxythiamine
CAS :<p>Oxythiamine (Hydroxythiamin) is a TK inhibitor that inhibits cancer cell proliferation, induces cell cycle arrest, and induces apoptosis.</p>Formule :C12H16N3O2SDegré de pureté :96.14% - 99.51%Couleur et forme :SolidMasse moléculaire :266.34Thalidomide-O-amido-C8-NH2
CAS :<p>Thalidomide-O-amido-C8-NH2 is a thalidomide-based ligand-linker for PROTAC synthesis.</p>Formule :C23H30N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.51DL-Sulforaphane N-acetyl-L-cysteine
CAS :<p>DL-Sulforaphane N-acetyl-L-cysteine (SFN-NAC), induces apoptosis through α-microtubulin and phosphorylation of ERK1/2-mediated Stathmin-1, and Hsp70 (NSCLC).</p>Formule :C11H20N2O4S3Couleur et forme :SolidMasse moléculaire :340.48Xerophilusin B
CAS :<p>Xerophilusin B from Isodon xerophilus halts ESCC cell growth, causes G2/M arrest, and induces apoptosis.</p>Formule :C20H26O5Couleur et forme :SolidMasse moléculaire :346.42Stem bromelain
CAS :<p>Stem bromelain: cysteine protease from pineapple stem with fibrinolytic, anti-inflammatory, antitumoral properties.</p>Couleur et forme :SolidThalidomide-O-C8-Boc
CAS :<p>Thalidomide-O-C8-Boc: CRBN ligand for PROTAC creation, derived from Thalidomide.</p>Formule :C26H34N2O7Couleur et forme :SolidMasse moléculaire :486.565Thalidomide-O-C8-COOH
CAS :<p>Thalidomide-O-C8-COOH, also known as Cereblon ligand 3, is a Thalidomide-derived compound that serves as a Cereblon (CRBN) ligand for the targeted recruitment</p>Formule :C22H26N2O7Couleur et forme :SolidMasse moléculaire :430.45Z-WEHD-FMK
CAS :<p>Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).</p>Formule :C37H42FN7O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :763.78ADPM06
CAS :<p>ADPM06: nonporphyrin PDT agent; leads in apoptosis, strong IC50 in µM against human tumors.</p>Formule :C34H24BBr2F2N3O2Couleur et forme :SolidMasse moléculaire :715.19Sterigmatocystine
CAS :<p>Sterigmatocystine, a G1 phase and DNA synthesis inhibitor, curbs p21 and is a mycotoxin precursor from Aspergillus versicolor.</p>Formule :C18H12O6Degré de pureté :98%Couleur et forme :Pale-Yellow Crystals Pale Yellow SolidMasse moléculaire :324.28Oenothein B
CAS :<p>Oenothein B inhibits PAR-glycohydrolase with antioxidant, anti-inflammatory, antifungal, anti-HCV, and antitumor effects.</p>Formule :C68H48O44Degré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :1569.08Glutathione arsenoxide hydrochloride
<p>Glutathione arsenoxide hydrochloride: anti-cancer, inhibits tumour metabolism, targets ANT, promotes apoptosis, marks cell proteins.</p>Formule :C18H26AsClN4O9SDegré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :584.86Targaprimir-96 TFA
<p>Targaprimir-96 TFA is a selective inhibitor of miR-96 in cancer, inducing apoptosis with high affinity for pri-miR-96 but not affecting healthy cells.</p>Formule :C79H103F3N18O9Couleur et forme :SolidMasse moléculaire :1505.77β-Glucuronide-dPBD-PEG5-NH2
CAS :<p>β-Glucuronide-dPBD-PEG5-NH2 is a β-glucuronide-linked pyrrolobenzodiazepine dimer that functions as a proagent for the synthesis of the antibody-drug conjugate</p>Formule :C78H101N7O35Couleur et forme :SolidMasse moléculaire :1696.66YF135
CAS :<p>YF135 is a reversible-covalent KRAS G12C PROTAC that degrades its target via the VHL-proteasome pathway.</p>Formule :C63H75ClN12O7SCouleur et forme :SolidMasse moléculaire :1179.86Opamtistomig
CAS :<p>Opamtistomig is a humanized monoclonal antibody immunoglobulin (H-γ1-scFv-L-κ) dimer targeting human programmed death-ligand 1 (PD-L1), CD274, and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). It is anticipated for use in research on various solid tumors and hematologic malignancies.</p>Couleur et forme :LiquidINF200
<p>INF200 (compound 5), a sulfonylurea-based inhibitor of NLRP3 and associated pyroptosis, exhibits cardiometabolic benefits in a rat model of high-fat diet (HFD)-</p>Formule :C13H13ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.71MRT-2359
CAS :<p>"MRT-2359: Oral GSPT1 reducer, anti-cancer, targets NSCLC/SCLC, effective on MYC-driven cells."</p>Formule :C22H17F4N3O6Degré de pureté :98.69%Couleur et forme :SoildMasse moléculaire :495.38rac-CCT-250863 HCl
<p>rac-CCT-250863 HCl: NEK 2 inhibitor, halts cell cycle, anti-cancer growth, boosts Pomalidomide-induced apoptosis.</p>Formule :C24H26ClF3N4O2SDegré de pureté :98.21%Couleur et forme :SoildMasse moléculaire :527PZ703b hydrochloride
<p>PZ703b hydrochloride, a Bcl-xl PROTAC, triggers apoptosis and halts cancer growth; used in bladder cancer studies.</p>Formule :C80H103Cl2F3N10O11S4Couleur et forme :SolidMasse moléculaire :1636.9Thalidomide-O-amido-C8-NH2 hydrochloride
<p>Thalidomide-O-amido-C8-NH2 hydrochloride, a synthetic cereblon ligand-linker for PROTAC synthesis.</p>Formule :C23H31ClN4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :494.97PI3Kα-IN-14
<p>PI3Kα-IN-14 (compound F8), a potent PI3Kα inhibitor, exhibits an IC50 value of 0.14 nM and markedly diminishes mitochondrial membrane potential, resulting in</p>Degré de pureté :98%Couleur et forme :Odour SolidPZ703b
CAS :<p>PZ703b is a novel BCL-XL PROTAC degrader with enhanced BCL-2 inhibition.</p>Formule :C80H102ClF3N10O11S4Couleur et forme :SolidMasse moléculaire :1600.44Shepherdin (79-87)
CAS :<p>Shepherdin 79-87: Amino acid fragment 79-87 of Hsp90/Survivin antagonist with anticancer properties.</p>Formule :C41H64N12O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :949.09BM-1244
CAS :<p>BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively.</p>Formule :C54H59ClF4N6O8S4Couleur et forme :SolidMasse moléculaire :1159.78RET ligand-3
<p>RETligand-3 is the ligand for PROTAC QZ2135, which targets RET.</p>Formule :C38H42N10O3Couleur et forme :SolidMasse moléculaire :686.81(±)-Enterodiol
CAS :<p>"(±)-Enterodiol, the racemate of Enterodiol, is metabolized from lignans found in whole-grain cereals, nuts, legumes, flaxseed, and vegetables by human intestinal bacteria. This compound exhibits apoptotic effects in colorectal cancer (CRC) cells and has been identified to possess anti-cancer activities [1] [2]."</p>Formule :C18H22O4Couleur et forme :SolidMasse moléculaire :302.36CDK8-IN-13
CAS :<p>CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity.</p>Formule :C14H11N3ODegré de pureté :99.28%Couleur et forme :SoildMasse moléculaire :237.26AKN-028
CAS :<p>AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.</p>Formule :C17H14N6Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :302.33BIM-46174 HCl
<p>BIM-46174 HCl is a G-protein inhibitor with anticancer activity that induces cysteine 3-dependent apoptosis.</p>Formule :C22H31ClN4OSDegré de pureté :99.77% - 99.77%Couleur et forme :SolidMasse moléculaire :435.03PG-11047 2HCl
<p>PG-11047 2HCl treats genitourinary, immune, genetic, ocular, blood/lymphatic disorders, and aids lymphoma/prostate cancer research.</p>Formule :C14H34Cl2N4Degré de pureté :97.47%Couleur et forme :SolidMasse moléculaire :329.35PROTAC TRIB2 degrader-1
<p>PROTAC TRIB2 degrader-1 (Compound 5k) is a potent TRIB2 degrader that selectively induces TRIB2 degradation via the CRBN-dependent ubiquitin-proteasome pathway. It effectively inhibits cell proliferation and induces cell apoptosis (apoptosis), making it useful in cancer research.</p>Formule :C45H45FN8O6Couleur et forme :SolidMasse moléculaire :812.89hMcl-1-IN-1
<p>hMcl-1-IN-1 (Compound 9) is an hMcl-1 inhibitor based on a His224 arylsulfonyl fluoride, displaying an IC50 value of 5.8 nM.</p>Formule :C69H113FN20O19SCouleur et forme :SolidMasse moléculaire :1577.82APG-1387
CAS :<p>APG-1387 inhibits IAPs, degrades cIAP1/2, XIAP, boosts chemosensitivity, and induces apoptosis in NPC.</p>Formule :C60H72N10O10S2Couleur et forme :SolidMasse moléculaire :1157.41sEH inhibitor-19
<p>sEH inhibitor-19 (Compound (R)-14i) is an orally active soluble epoxide hydrolase (sEH) inhibitor with an IC50 of 1.2 nM. This compound suppresses the expression of TNF-α and IL-6 and exhibits anti-inflammatory effects in mouse models of acute pancreatitis and Carrageenan-induced edema.</p>Formule :C28H28F3N3O4Couleur et forme :SolidMasse moléculaire :527.535Z-Ala-Ala-Asp-CMK
CAS :<p>Z-Ala-Ala-Asp-CMK (Z-AAD-CMK) is a selective granzyme B inhibitor that blocks granzyme B protease activity, for inflammatory diseases and tumours.</p>Formule :C19H24ClN3O7Degré de pureté :99.967%Couleur et forme :SolidMasse moléculaire :441.86Spexin TFA
<p>Spexin TFA: GAL2/GAL3 agonist (EC50: 45.7/112.2 nM), no activity at GAL1, reduces appetite, fatty acid uptake, and LH secretion; anxiolytic.</p>Formule :C76H115F3N20O21SCouleur et forme :SolidMasse moléculaire :1733.9WKYMVM
CAS :<p>WKYMVM is a N-formyl peptide receptor (FPR1) agonist.</p>Formule :C41H61N9O7S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :856.11Anagrelide hydrochloride monohydrate
CAS :<p>Anagrelide HCl monohydrate is a platelet-reducing imidazoquinazoline for ET and PV research.</p>Formule :C10H10Cl3N3O2Couleur et forme :SolidMasse moléculaire :310.56Ganglioside GD3 disodium salt
CAS :<p>Ganglioside GD3 disodium salt is a melanoma-associated antigen often targeted in immune therapy for melanomas.</p>Formule :C70H123N3Na2O29Couleur et forme :SolidMasse moléculaire :1516.71R1-ICR-5
CAS :<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formule :C54H70N8O7S2Couleur et forme :SolidMasse moléculaire :1007.31Ferroptosis-IN-14
<p>Ferroptosis-IN-14 (compund 36) exhibits the most potent anti-ferroptotic activity with an EC50 value of 0.58 ± 0.02 μM, demonstrating excellent anti-ferroptotic efficacy, as well as stability in microsomes and plasma.</p>Couleur et forme :Odour SolidTaltirelin acetate
CAS :<p>Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an</p>Formule :C19H27N7O7Degré de pureté :99.21%Couleur et forme :SolidMasse moléculaire :465.46Verdinexor
CAS :<p>Verdinexor (KPT-335) (KPT-335), a specific XPO1/CRM1 inhibitor, are orally bioavailable.</p>Formule :C18H12F6N6ODegré de pureté :98% - 99.68%Couleur et forme :SolidMasse moléculaire :442.32Antitumor agent-64
CAS :<p>Antitumor Agent-64 (Compound 8d), a diosgenin derivative, exhibits potent cytotoxic activity against the A549 cell line and induces apoptosis in A549 cells</p>Formule :C35H47N3O3SCouleur et forme :SolidMasse moléculaire :589.83HTR2A antagonist 1
<p>HTR2A antagonist 1 (Compound 15f) is an HTR2A antagonist with an IC50 of 42.79 nM. It induces sub-G1 cell cycle arrest and apoptosis in colorectal cancer cells by activating the p53/p21/caspase 3 signaling pathway. HTR2A antagonist 1 exhibits good liver microsomal stability and is useful for colorectal cancer research.</p>Formule :C35H43Cl2F2N5O4Couleur et forme :SolidMasse moléculaire :706.65Xylopine
CAS :<p>Xylopine: an aporphine alkaloid, cytotoxic to cancer cells, induces oxidative stress, G2/M arrest, and apoptosis.</p>Formule :C18H17NO3Couleur et forme :SolidMasse moléculaire :295.33Verproside
CAS :<p>Verproside is a useful organic compound for research related to life sciences. The catalog number is T124745 and the CAS number is 50932-20-2.</p>Formule :C22H26O13Couleur et forme :SolidMasse moléculaire :498.437Bromoiodoacetamide
CAS :<p>Bromoiodoacetamide (I-HAcAm): cytotoxic, induces ROS & apoptosis in HepG-2 cells.</p>Formule :C2H3BrINOCouleur et forme :SolidMasse moléculaire :263.86KP1019
CAS :<p>KP1019 is now discontinued.</p>Formule :C21H19Cl4N6RuCouleur et forme :SolidMasse moléculaire :598.30SC-2001
CAS :<p>SC-2001 inhibits MCL-1 and STAT3, enhances SHP-1, induces apoptosis in breast cancer, and counters STAT3-driven sorafenib resistance in liver cancer.</p>Formule :C18H14BrN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :368.23YJ1206
CAS :<p>YJ1206 is a highly potent and selective CDK12/13 PROTAC degrader oral, DNA damage and cell-cycle arrest,and inhibits the proliferation of prostate cancer cells.</p>Formule :C49H52FN11O5Degré de pureté :97.14%Couleur et forme :SolidMasse moléculaire :894.01eIF4A3-IN-7
CAS :<p>eIF4A3-IN-7: Potent eIF4A3 inhibitor, potential cancer/dysproliferation research (WO2019161345A1, Compound 8).</p>Formule :C26H25NO7Couleur et forme :SolidMasse moléculaire :463.486N-Acetylpsychosine
CAS :<p>N-Acetylpsychosine, also known as α-galactosylated C2-ceramide (d18:1/2:0), exhibits immunostimulatory properties.</p>Formule :C26H49NO8Couleur et forme :SolidMasse moléculaire :503.67MG-C-30
CAS :<p>MG-C-30 is an orally active CD27 agonist with an EC50 of 0.84 μM. It activates co-stimulatory signaling in NK cells and T cells, thereby enhancing the immune response. In the EG7-OVA mouse model, MG-C-30 demonstrates antitumor activity.</p>Formule :C24H26N4O3SCouleur et forme :SolidMasse moléculaire :450.55Lorigerlimab
CAS :<p>Lorigerlimab (MGD019) is a bispecific IgG4 DART that blocks PD-1/CTLA-4, enhancing T-cells for mCRPC research.</p>Couleur et forme :LiquidSilicon naphthalocyanine dichloride
CAS :<p>Silicon naphthalocyanine dichloride is a photosensitizer with potential anti-tumor activity. This compound is employed in photodynamic therapy to inhibit cancer by effectively absorbing specific wavelengths of light, thereby generating oxygen radicals that aid in the destruction of cancer cells. The biocompatibility of Silicon naphthalocyanine dichloride demonstrates promising prospects for medical applications.</p>Formule :C48H24Cl2N8SiCouleur et forme :SolidMasse moléculaire :811.75Sodium propionate
CAS :<p>Sodium propionate (Propionic acid sodium salt) has potential anti-inflammatory and anti-apoptotic activities, inhibiting certain signaling pathways.</p>Formule :C3H5NaO2Couleur et forme :SoildMasse moléculaire :96.06Phosphocreatine dipotassium
CAS :<p>Phosphocreatine dipotassium, primarily found in the skeletal muscles of vertebrates and one of organic compounds known as alpha amino acids and derivatives.</p>Formule :C4H8K2N3O5PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.29(E/Z)-LAQ824
CAS :<p>(E/Z)-LAQ824 is an inhibitor of histone deacetylase.</p>Formule :C22H25N3O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :379.46Trimebutine
CAS :<p>Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid</p>Formule :C22H29NO5Degré de pureté :98.13% - 99.49%Couleur et forme :SolidMasse moléculaire :387.47Solanidine
CAS :<p>Solanidine is a cholestane alkaloid isolated from potato species with antitumor effects. Solanidine inhibits proliferation.</p>Formule :C27H43NODegré de pureté :96.83%Couleur et forme :SolidMasse moléculaire :397.64hCAIX-IN-13
CAS :<p>hCAIX-IN-13 (Pt2) inhibits CAIX with 6.57 μM IC50, curbs cancer cell growth, and induces apoptosis for cancer research.</p>Formule :C37H33F3N6O7PtS2Couleur et forme :SolidMasse moléculaire :989.9Anticancer agent 134
<p>Anticancer Agent 134 (Compound 6a), an environment-sensitive fluorescent probe, induces apoptosis and selectively differentiates between tumor and normal</p>Formule :C34H36ClN7O3S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :690.28Cytostatin
CAS :<p>Cytostatin: Natural antitumor, inhibits cell adhesion, blocks B16 melanoma, induces apoptosis, selectively targets PP2A (IC50 = 29 nM).</p>Formule :C21H33O7PCouleur et forme :SolidMasse moléculaire :428.462MBC-11 trisodium
CAS :<p>MBC-11 trisodium, a bisphosphonate-Ara-C conjugate, may treat TIBD.</p>Formule :C11H17N3Na3O14P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :577.16Lipustobart
CAS :<p>Lipustobart is an IgG4-kappa humanized monoclonal antibody targeting PDCD1 (programmed cell death 1, PD1, PD-1, CD279), with immunostimulant and antineoplastic</p>Degré de pureté :98%Couleur et forme :LiquidTAT-NEP1-40 acetate
<p>TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose</p>Formule :C268H438N88O77·xC2H4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :6124.89 (free base)Beclin1-Bcl-2 interaction inhibitor 1
<p>Beclin1-Bcl-2 Interaction Inhibitor 1 effectively disrupts the binding of Beclin 1 to Bcl-2, and is utilized in cancer and neurodegeneration research [1].</p>Couleur et forme :Odour SolidAnticancer agent 39
CAS :<p>Compound B12, a JOA derivative, collapses MMP to induce apoptosis, inhibits cloning/migration, and has an IC50 of 0.39 μM against HGC-27 cells.</p>Formule :C50H65N5O10Couleur et forme :SolidMasse moléculaire :896.08GSK-3β inhibitor 15
<p>GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-</p>Formule :C17H16N6OSCouleur et forme :SolidMasse moléculaire :352.41Danburstotug
CAS :<p>Danburstotug (IMC-001), an immunostimulant and antineoplastic [1], is a humanized IgG1-lambda monoclonal antibody targeting CD274 (PDL1, B7 homologue 1, B7H1).</p>Degré de pureté :98%Couleur et forme :LiquidAcrixolimab
CAS :<p>Acrixolimab is a humanized IgG4-κ monoclonal antibody that selectively targets PD-1 [1] [2].</p>Degré de pureté :98%Couleur et forme :LiquidFeladilimab
CAS :<p>Feladilimab (GSK3359609) is an IgG4 monoclonal antibody that is an ICOS agonist.</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:98%Couleur et forme :LiquidMasse moléculaire :145.24 kDaFD2157
<p>FD2157, a photosensitive PI3K inhibitor, exhibits inhibitory IC50 values of 43 nM for PI3Kα, 83 nM for PI3Kβ, 84 nM for PI3Kγ, and 14 nM for PI3Kδ.</p>Formule :C27H21ClN6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :625.01PD-1/PD-L1-IN-48
<p>PD-1/PD-L1-IN-48 (compound HD10) is an effective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 3.1 nM. It plays a vital role in cancer research.</p>Couleur et forme :Odour SolidPROTAC NCOA4 degrader-1
<p>PROTACNCOA4 degrader-1 (Compound V3) is a PROTAC-based degrader of NCOA4, exhibiting a DC50 of 3 nM in HeLa cells. Besides acting as a ferroptosis inhibitor, this compound effectively reduces the levels of NCOA4 and decreases intracellular ferrous (Fe2+) levels. Moreover, PROTACNCOA4 degrader-1 ameliorates liver damage in a CCl4-induced acute liver injury model.</p>Couleur et forme :Odour SolidHuman PD-L1 inhibitor II
CAS :<p>Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.</p>Formule :C103H151N25O30Couleur et forme :SolidMasse moléculaire :2219.486Haemanthamine hydrochloride
<p>Haemanthamine hydrochloride, an alkaloid from Amaryllidaceae, has anticancer, antioxidant, antiviral, antimalarial, and anticonvulsant properties.</p>Formule :C17H20ClNO4Couleur et forme :SolidMasse moléculaire :337.8EGFR-IN-143
<p>EGFR-IN-143 (Compound 5f) is a potent EGFR inhibitor with an IC50 value of 0.15 μM. It induces apoptosis by arresting the cell cycle at the G2/M phase and exhibits antitumor activity.</p>Formule :C20H21ClN6O3Couleur et forme :SolidMasse moléculaire :428.872TrxR-IN-7
<p>TrxR-IN-7 (14f) is a potent inhibitor of thioredoxin reductase (TrxR), with an IC50 value of 3.5 µM. It exhibits antiproliferative activity and can induce apoptosis and the production of reactive oxygen species (ROS).</p>Formule :C22H21NO3Couleur et forme :SolidMasse moléculaire :347.407TS-IN-5
<p>TS-IN-5 (Compound 15) is an inhibitor of thymidylate synthase (TS). It induces apoptosis by modulating the proteins Bax, BCL-2, PI3K, and STAT1. TS-IN-5 exhibits antitumor activity against liver cancer, breast cancer, and colon cancer.</p>Formule :C16H17N5OSCouleur et forme :SolidMasse moléculaire :327.404Thymidine 3',5'-diphosphate tetrasodium
CAS :<p>Thymidine 3',5'-diphosphate tetrasodium inhibits staphylococcal nuclease, SND1 & tyrosyl nuclease; has anti-tumor properties & catalyzes biochemical reactions.</p>Formule :C10H12N2Na4O11P2Couleur et forme :SolidMasse moléculaire :490.12Mcl-1 inhibitor 3
CAS :<p>Mcl-1 inhibitor 3 shows good pharmacokinetic properties and excellent in vivo efficacy without toxicity.Mcl-1 inhibitor 3 is a highly potent and orally activate</p>Formule :C40H52ClF2N5O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :820.39
