CymitQuimica logo
Apoptose

Apoptose

Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.

Sous-catégories appartenant à la catégorie "Apoptose"

Affichez 6 plus de sous-catégories

6225 produits trouvés pour "Apoptose"

Trier par

Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
produits par page.
  • Oxidopamine hydrobromide

    CAS :
    Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.
    Formule :C8H12BrNO3
    Degré de pureté :98.22% - 99.88%
    Couleur et forme :Beige To Brown Fine Crystalline Powder
    Masse moléculaire :250.09

    Ref: TM-T12352L

    50mg
    34,00€
    100mg
    50,00€
    500mg
    148,00€
  • Nitrendipine

    CAS :
    Nitrendipine is a vasodilating calcium channel blocker and antihypertensive that preserves kidney function and promotes sodium excretion.
    Formule :C18H20N2O6
    Degré de pureté :99% - 99.55%
    Couleur et forme :Solid
    Masse moléculaire :360.36

    Ref: TM-T0119

    10mg
    35,00€
    25mg
    52,00€
    1mL*10mM (DMSO)
    52,00€
    50mg
    67,00€
    100mg
    113,00€
    200mg
    172,00€
    500mg
    268,00€
    1g
    414,00€
  • Etoposide

    CAS :

    Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM).

    Formule :C29H32O13
    Degré de pureté :99.19% - 99.94%
    Couleur et forme :Crystals From Methanol Solid
    Masse moléculaire :588.56

    Ref: TM-T0132

    50mg
    39,00€
    100mg
    52,00€
    500mg
    106,00€
    1g
    155,00€
  • Deferoxamine Mesylate

    CAS :
    Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.
    Formule :C26H52N6O11S
    Degré de pureté :94.68% - 99.8%
    Couleur et forme :Solid
    Masse moléculaire :656.79

    Ref: TM-T1637

    50mg
    34,00€
    1mL*10mM (DMSO)
    44,00€
    100mg
    50,00€
    500mg
    81,00€
  • Human TNFRSF1B(Tumor Necrosis Factor Receptor Superfamily, Member 1B) ELISA Kit


    The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TNFRSF1B. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TNFRSF1B. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human TNFRSF1B, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TNFRSF1B in the samples is then determined by comparing the OD of the samples to the standard curve.
    Couleur et forme :Colourless Transparentliquid

    Ref: EK-ELK1346

    48T
    334,00€
    96T
    443,00€
    5x96T
    1.880,00€
  • Tetraethylenepentamine Pentahydrochloride

    CAS :
    Tetraethylenepentamine Pentahydrochloride is a high affinity copper and zinc chelator.
    Formule :C8H23N5·5HCl
    Degré de pureté :≥95%
    Couleur et forme :Solid
    Masse moléculaire :371.61

    Ref: TM-T2229

    1mL*10mM (DMSO)
    44,00€
    25mg
    46,00€
    50mg
    50,00€
    100mg
    60,00€
    500mg
    123,00€
    1g
    177,00€
  • Mouse VEGFA(Vascular Endothelial Growth Factor A) ELISA Kit


    The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse VEGFA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse VEGFA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse VEGFA, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse VEGFA in the samples is then determined by comparing the OD of the samples to the standard curve.
    Couleur et forme :Colourless Transparentliquid

    Ref: EK-ELK1293

    48T
    332,00€
    96T
    443,00€
    5x96T
    1.880,00€
  • Mouse Bcl2(B-Cell Leukemia/Lymphoma 2) ELISA Kit


    The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse Bcl2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse Bcl2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse Bcl2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse Bcl2 in the samples is then determined by comparing the OD of the samples to the standard curve.
    Couleur et forme :Colourless Transparentliquid

    Ref: EK-ELK1526

    48T
    402,00€
    96T
    539,00€
    5x96T
    2.290,00€
  • Doxorubicin hydrochloride

    CAS :
    Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).
    Formule :C27H29NO11·HCl
    Degré de pureté :98% - 99.52%
    Couleur et forme :Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)
    Masse moléculaire :579.99

    Ref: TM-T1020

    25mg
    38,00€
    50mg
    50,00€
    1mL*10mM (DMSO)
    52,00€
    100mg
    71,00€
    200mg
    92,00€
    500mg
    168,00€
    1g
    249,00€
  • Mouse AIF(Apoptosis Inducing Factor) ELISA Kit


    The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse AIF. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse AIF. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse AIF, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse AIF in the samples is then determined by comparing the OD of the samples to the standard curve.
    Couleur et forme :Colourless Transparentliquid

    Ref: EK-ELK8448

    48T
    402,00€
    96T
    539,00€
    5x96T
    2.290,00€
  • Lovastatin

    CAS :
    Lovastatin (MK-803) is an HMG-CoA reductase inhibitor. Lovastatin lowers cholesterol and is used as a lipid-lowering agent. Cost-effective and quality-assured.
    Formule :C24H36O5
    Degré de pureté :99.66% - 99.92%
    Couleur et forme :The Substance Is A White-Yellowish To Yellow Powder Solid Powder
    Masse moléculaire :404.54

    Ref: TM-T1207

    1mL*10mM (DMSO)
    34,00€
    25mg
    38,00€
    50mg
    52,00€
    100mg
    69,00€
    200mg
    87,00€
    500mg
    142,00€
    1g
    202,00€
  • LZ-07


    LZ-07 is an IRAK4 PROTAC degrader (DC50 = 1.14 nM), that, upon degradation of IRAK4, significantly inhibits the expression of cytokines such as IL-6, IL-1β, TNF-α, and IL-10. It is applicable in research related to autoimmune diseases.
    Couleur et forme :Odour Solid

    Ref: TM-T206708

    10mg
    À demander
    50mg
    À demander
  • IBI-325


    IBI-325 is a humanized monoclonal antibody inhibitor targeting CD73. It completely inhibits CD73 enzymatic activity without causing a hook effect. IBI-325 can reverse adenosine monophosphate-mediated immunosuppression and significantly inhibits T cell proliferation and the release of cytokines (IL-2, IFN-γ, and TNF-α). In both hPBMC-reconstituted mouse models and hCD73 knock-in mouse models, IBI-325 demonstrates potent antitumor activity. This compound is applicable for cancer immunotherapy research.
    Couleur et forme :Odour Liquid

    Ref: TM-T9901A-1902

    1mg
    À demander
    5mg
    À demander
  • Caspase-3/7 activator 1


    Caspase-3/7 activator 1 is an effective activator of Caspase-3/7 that exhibits tumor-selective, antiproliferative activity and high apoptosis (Apoptosis) induction capability.
    Formule :C26H28N2O5
    Masse moléculaire :448.19982

    Ref: TM-T209473

    10mg
    À demander
    50mg
    À demander
  • SB-T-1214

    CAS :
    SB-T-1214 (SBT) is a taxane-based drug known for its ability to effectively suppress the expression of stem cell-related genes (Oct4, Sox2, and c-Myc) and induce apoptosis in drug-resistant tumorigenic CD133+/CD44+ colon cancer spheroids. In Pgp+ DLD-1 human colon tumor xenograft mouse models, SB-T-1214 successfully inhibits tumor growth. This compound is relevant for anti-tumor research, particularly against drug-resistant tumors such as colon, pancreatic, and renal cancers.
    Formule :C45H59NO15
    Couleur et forme :Solid
    Masse moléculaire :853.95

    Ref: TM-T210736

    10mg
    À demander
    50mg
    À demander
  • dASK1-VHL


    dASK1-VHL is an orally active PROTAC degrader targeting ASK1. It effectively binds to VHL, promoting the selective degradation of ASK1. By reducing ASK1 protein levels, dASK1-VHL inhibits the activation of p38 MAPK and decreases liver lipid content, offering new insights for MASH research.
    Couleur et forme :Odour Solid

    Ref: TM-T210975

    10mg
    À demander
    50mg
    À demander
  • Caerin 1.1 TFA


    Caerin 1.1 TFA, a host defense peptide derived from the Australian tree frog Litoria's glandular secretions, exhibits anti-proliferative effects on HeLa cells
    Degré de pureté :98%
    Couleur et forme :Odour Solid

    Ref: TM-T82793

    5mg
    À demander
    50mg
    À demander
  • 1R,3R-RSL3

    CAS :
    1R,3R-RSL3 is a negative control for1S, 3R-RSL3.
    Formule :C23H21ClN2O5
    Couleur et forme :Solid
    Masse moléculaire :440.88

    Ref: TM-T41203

    10mg
    862,00€
    50mg
    3.529,00€
  • SHOC2-RAS PPI-IN-1


    SHOC2–RAS PPI-IN-1 (compound 6) is a non-covalent competitive inhibitor that targets the interaction between SHOC2 and RAS proteins. It exhibits an IC50 of 0.048 μM and a KD of 0.065 μM against NRASQ61R. This compound inhibits SMP phosphatase-complex activity, increasing CRAFS259 phosphorylation levels and thus blocking the MAPK signaling pathway (by reducing pMEK and pERK levels). It induces cell cycle arrest and apoptosis in tumor cells. SHOC2–RAS PPI-IN-1 is used in targeting studies for malignancies, such as NRASQ61R-mutant melanoma and colorectal cancer.
    Couleur et forme :Odour Solid

    Ref: TM-T211221

    10mg
    À demander
    50mg
    À demander
  • Bcl-2-IN-14


    Bcl-2-IN-14 (Compound 13c), a BCL-2 inhibitor, exhibits an inhibitory concentration (IC 50) of 0.471 μM, and is applicable in cancer research [1].
    Couleur et forme :Odour Solid

    Ref: TM-T82912

    5mg
    À demander
    50mg
    À demander