Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5593 produits trouvés pour "Apoptose"
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Fenobam hydrate
CAS :<p>Fenobam hydrate blocks mGluR5, preventing calcium mobilization, and may reduce stress, anxiety, and pain.</p>Formule :C11H13ClN4O3Couleur et forme :SolidMasse moléculaire :284.7BG45
CAS :<p>BG45 is an HDAC I type inhibitor with IC50 of 289 nM, 2.0 μM, 2.2 μM and >20 μM for HDAC3/1/2/6 in cell-free assays, respectively.</p>Formule :C11H10N4ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :214.22R406
CAS :<p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>Formule :C22H23FN6O5·C6H6O3SDegré de pureté :97.67% - 98.82%Couleur et forme :SolidMasse moléculaire :628.63PS-1145
CAS :<p>PS-1145 (IKK Inhibitor X) is a specific IKK inhibitor with IC50 of 88 nM.</p>Formule :C17H11ClN4ODegré de pureté :98.81% - >99.99%Couleur et forme :SolidMasse moléculaire :322.75Lorlatinib
CAS :<p>Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogene</p>Formule :C21H19FN6O2Degré de pureté :99.77% - 99.95%Couleur et forme :SolidMasse moléculaire :406.41GW 441756
CAS :<p>GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.</p>Formule :C17H13N3ODegré de pureté :97.73% - 99.8%Couleur et forme :SolidMasse moléculaire :275.3Methoxychlor
CAS :<p>Methoxychlor, an organochlorine pesticide, is thought to be an endocrine disrupter that affects Ca2 homeostasis and cell viability in different cell models.</p>Formule :C16H15Cl3O2Degré de pureté :98.82% - ≥95%Couleur et forme :Colorless Crystals (Technical Grey Powder) To The Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment IfMasse moléculaire :345.65Taurochenodeoxycholic Acid
CAS :<p>Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.</p>Formule :C26H45NO6SDegré de pureté :99.53% - 99.86%Couleur et forme :SolidMasse moléculaire :499.7MGH-CP1
CAS :<p>MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.</p>Formule :C20H24N4OSDegré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :368.5Liproxstatin-1 hydrochloride
CAS :<p>Liproxstatin-1 hydrochloride is a high-potency ferroptosis inhibitor capable of effectively preventing ferroptotic cell death, with an IC50 value of 22 nM [1].</p>Formule :C19H22Cl2N4Couleur et forme :SolidMasse moléculaire :377.31Benidipine
CAS :<p>Benidipine: potent oral calcium blocker, boosts nitric oxide synthase, enhances coronary flow, protects heart cells post-ischemia.</p>Formule :C28H31N3O6Couleur et forme :SolidMasse moléculaire :505.56BAY 61-3606 dihydrochloride
CAS :<p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>Formule :C20H18N6O3·2HClDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :463.32Lycorine
CAS :<p>Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.</p>Formule :C16H17NO4Degré de pureté :98.60% - 99.95%Couleur et forme :SolidMasse moléculaire :287.312BAct
CAS :<p>2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress response</p>Formule :C19H16ClF3N4O3Degré de pureté :97.97% - 99.04%Couleur et forme :SolidMasse moléculaire :440.8Irigenin
CAS :<p>Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the Extra</p>Formule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31GSK778 hydrochloride
CAS :<p>GSK778 hydrochloride is a selective BET BD1 bromodomain inhibitor, with IC50s ranging from 41 to 143 nM, effective in cancer models.</p>Formule :C30H34ClN5O3Degré de pureté :97.26% - 98.35%Couleur et forme :SolidMasse moléculaire :548.08Thalidomide-4-OH
CAS :<p>Thalidomide-4-OH, a Thalidomide-derived Cereblon binder, recruits CRBN and serves as a PROTAC linker.</p>Formule :C13H10N2O5Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :274.23Niraparib
CAS :<p>Niraparib (MK-4827) inhibits PARP1/PARP2 (IC50: 3.8/2.1 nM), effective on BRCA mutant cancers, 330x less effective on PARP3, V-PARP, Tank1.</p>Formule :C19H20N4ODegré de pureté :98% - 99.91%Couleur et forme :SolidMasse moléculaire :320.39Thalidomide-NH-C4-NH-Boc
CAS :<p>Thalidomide-NH-C4-NH-Boc is a cereblon-based E3 ligase ligand-linker for PROTACs.</p>Formule :C22H28N4O6Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :444.48Difurazon hydrochloride
CAS :<p>Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.</p>Formule :C14H13ClN6O6Degré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :396.74ML141
CAS :<p>ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).</p>Formule :C22H21N3O3SDegré de pureté :99.36% - 99.56%Couleur et forme :SolidMasse moléculaire :407.49Notoginsenoside R1
CAS :<p>Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.</p>Formule :C47H80O18Degré de pureté :99.57% - >99.99%Couleur et forme :SolidMasse moléculaire :933.13SW106065
CAS :<p>SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.</p>Formule :C10H8N2OSDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :204.25(S)-(+)-Rolipram
CAS :<p>(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in the</p>Formule :C16H21NO3Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :275.34B-AP15
CAS :<p>B-AP15 (NSC-687852) selectively inhibits 26S proteasome enzymes Usp14 and UCHL5, blocking their activity.</p>Formule :C22H17N3O6Degré de pureté :91.43% - 98.77%Couleur et forme :SolidMasse moléculaire :419.39Methoxyamine HCl
CAS :<p>Methoxyamine HCl targets DNA repair sites, potentially increasing DNA breaks and enhancing alkylating agents' anti-cancer effects.</p>Formule :CH6ClNODegré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :83.51Lupeol
CAS :<p>Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.</p>Formule :C30H50ODegré de pureté :98% - 99.96%Couleur et forme :Needles From Alcohol Acetone White PowderMasse moléculaire :426.72Valproic Acid
CAS :<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Formule :C8H16O2Degré de pureté :97.78% - 99%Couleur et forme :Colourless To Pale Yellow Liquid ViscousMasse moléculaire :144.21Carvacrol
CAS :<p>1.</p>Formule :C10H14ODegré de pureté :99.05%Couleur et forme :Needles LiquidMasse moléculaire :150.22Triptonide
CAS :<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Formule :C20H22O6Degré de pureté :99.11% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :358.39LY2857785
CAS :<p>LY2857785 is a type I competitive and reversible ATP kinase inhibitor against CDK7/CDK8/CDK9 (IC50s: 246 nM/16 nM/11 nM).</p>Formule :C26H36N6ODegré de pureté :99.68%Couleur et forme :Solid PowderMasse moléculaire :448.6MFCD01917484
CAS :<p>MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.</p>Formule :C14H15NO3SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :277.34Taccalonolide A
CAS :<p>Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is</p>Formule :C36H46O14Degré de pureté :98.16% - 99.4%Couleur et forme :SolidMasse moléculaire :702.74Alogliptin Benzoate
CAS :<p>Alogliptin Benzoate, a potent DPP-4 inhibitor with >10,000-fold selectivity over DPP-8/9, may also curb TLR-4-induced inflammation.</p>Formule :C25H27N5O4Degré de pureté :99.94% - >99.99%Couleur et forme :White PowderMasse moléculaire :461.51α-Thujone
CAS :<p>α-Thujone is an inhibitor of ACh with an IC50 value of 24.7μM.</p>Formule :C10H16ODegré de pureté :97.02% - 98.41%Couleur et forme :Less Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996) Colorless Or Almost Colorless Liquid With A Menthol- Like Odor (Albert-Puleo 1978; Budavari 1996)Masse moléculaire :152.23Onatasertib
CAS :<p>Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.</p>Formule :C21H27N5O3Degré de pureté :99.14% - 99.97%Couleur et forme :SolidMasse moléculaire :397.47Topotecan hydrochloride hydrate
CAS :<p>Orally active Topotecan HCl hydrate inhibits Topoisomerase I, blocks G0/G1 & S phases, and induces apoptosis.</p>Formule :C23H26ClN3O6Couleur et forme :SolidMasse moléculaire :475.93β-Elemonic Acid
CAS :<p>β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.</p>Formule :C30H46O3Degré de pureté :99.61% - 99.8%Couleur et forme :SolidMasse moléculaire :454.68Tomivosertib HCl
CAS :<p>Tomivosertib (eFT508) is a MNK1/2 inhibitor that blocks eIF4E phosphorylation, hindering tumor growth and immune signaling.</p>Formule :C17H21ClN6O2Couleur et forme :SolidMasse moléculaire :376.845BAY 11-7082
CAS :<p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>Formule :C10H9NO2SDegré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :207.25YUM70
CAS :<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Formule :C21H19ClN2O4Degré de pureté :97.25%Couleur et forme :SolidMasse moléculaire :398.84PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Formule :C130H206N42O45SDegré de pureté :96.64%Couleur et forme :SolidMasse moléculaire :3109.35(6R)-FR054
CAS :<p>(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.</p>Formule :C14H19NO8Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :329.3TW-37
CAS :<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Formule :C33H35NO6SDegré de pureté :97.06% - ≥95%Couleur et forme :SolidMasse moléculaire :573.7Abacavir sulfate
CAS :<p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>Formule :C14H18N6OH2O4SDegré de pureté :99.79% - 99.85%Couleur et forme :White To Off-White SolidMasse moléculaire :335.38OICR-9429
CAS :<p>OICR-9429 blocks WDR5 binding to MLL/Histone 3, hindering acute myeloid leukemia cell growth in vitro.</p>Formule :C29H32F3N5O3Degré de pureté :97.07% - 99.93%Couleur et forme :SolidMasse moléculaire :555.59(-)-Epipodophyllotoxin
CAS :<p>(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.</p>Formule :C22H22O8Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :414.41Thalidomide-O-amido-PEG3-C2-NH2 TFA
CAS :<p>Synthetic E3 ligase ligand-linker, Thalidomide-O-amido-PEG3-C2-NH2 TFA, used in PROTAC with cereblon ligand and PEG.</p>Formule :C25H31F3N4O11Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :620.54Bigelovin
CAS :<p>Bigelovin: RXRα agonist, inhibits mTOR via ROS, induces apoptosis/autophagy, anti-tumor sesquiterpene from Inula sp.</p>Formule :C17H20O5Degré de pureté :99.61% - 99.72%Couleur et forme :SolidMasse moléculaire :304.34KRCA-0008
CAS :<p>KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.</p>Formule :C30H37ClN8O4Degré de pureté :96.19%Couleur et forme :SolidMasse moléculaire :609.12Perhexiline
CAS :<p>Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.</p>Formule :C19H35NCouleur et forme :SolidMasse moléculaire :277.49Verbascoside
CAS :<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Formule :C29H36O15Degré de pureté :97.46% - 99.55%Couleur et forme :SolidMasse moléculaire :624.59Ketorolac hemicalcium
CAS :<p>Ketorolac hemicalcium: NSAID, COX-1/COX-2 inhibitor (IC50: 20/120 nM), treats eye inflammation & pain, used in cancer research.</p>Formule :C30H24CaN2O6Couleur et forme :SolidMasse moléculaire :548.608BTdCPU
CAS :<p>BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.</p>Formule :C13H8Cl2N4OSDegré de pureté :98.94% - 99.59%Couleur et forme :SolidMasse moléculaire :339.2Thalidomide-propargyl
CAS :<p>Thalidomide-propargyl, a Cereblon ligand, links proteins in PROTAC formation.</p>Formule :C16H12N2O5Degré de pureté :95.14%Couleur et forme :SolidMasse moléculaire :312.28PD173074
CAS :<p>PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.</p>Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Thalidomide-NH-C6-NH2 hydrochloride
CAS :<p>Pomalidomide-C6-NH2 HCl is a synthetic conjugate for PROTAC, combining CRBN ligand and linker.</p>Formule :C19H25ClN4O4Degré de pureté :99.27%Couleur et forme :SolidMasse moléculaire :408.88BC-1258
CAS :<p>BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.</p>Formule :C22H22N4S2Degré de pureté :97.48% - 99.64%Couleur et forme :SolidMasse moléculaire :406.57Britannin
CAS :<p>Britannin, a sesquiterpene lactone, inhibits proliferation and induces apoptosis through the mitochondrial signaling pathway in human breast cancer cells.</p>Formule :C19H26O7Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :366.41Echinocystic acid
CAS :<p>EA, a natural triterpene, is found in herbs; it has anti-inflammatory and antioxidant properties.</p>Formule :C30H48O4Degré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :472.7Verteporfin
CAS :<p>Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions.</p>Formule :C41H42N4O8Degré de pureté :95.37% - 99.82%Couleur et forme :Dark Green To Black SolidMasse moléculaire :718.79Sulfaphenazole
CAS :<p>Sulfaphenazole (Plisulfan) is an inhibitor of CYP2C9 (Ki: 0.3 μM) that demonstrates at least 100-fold selectivity over other CYP450 isoforms (Ki: 63/29 μM for</p>Formule :C15H14N4O2SDegré de pureté :97.53% - 99.67%Couleur et forme :SolidMasse moléculaire :314.36Quinidine
CAS :<p>Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.</p>Formule :C20H24N2O2Degré de pureté :97.03% - 99.99%Couleur et forme :Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :324.42Nur77 modulator 1
CAS :<p>Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.</p>Formule :C28H25N5O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :495.6Nelarabine
CAS :<p>Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.</p>Formule :C11H15N5O5Degré de pureté :98.10% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Pseudolaric Acid B
CAS :<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Formule :C23H28O8Degré de pureté :98.91% - 99.84%Couleur et forme :SolidMasse moléculaire :432.46PK11000
CAS :<p>PK11000 is a p53 targeting compound, has anti-tumor activities through activation of unstable p53.</p>Formule :C6H5ClN2O4SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :236.63JNJ-7706621
CAS :<p>JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.</p>Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36Abacavir monosulfate
CAS :<p>Abacavir monosulfate: oral HIV inhibitor, anticancer; crosses blood-brain barrier, suppresses telomerase.</p>Formule :C14H20N6O5SCouleur et forme :SolidMasse moléculaire :384.41KRIBB11
CAS :<p>KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.</p>Formule :C13H12N6O2Degré de pureté :97.25% - 99.91%Couleur et forme :SolidMasse moléculaire :284.27Afimetoran
CAS :<p>Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.</p>Formule :C26H32N6ODegré de pureté :99.81% - 99.94%Couleur et forme :SolidMasse moléculaire :444.57Benidipine hydrochloride
CAS :<p>Benidipine hydrochloride (Coniel) , a hydrochloride salt form of benidipine, is used as a blocker of dihydropyridine calcium channel.</p>Formule :C28H32ClN3O6Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :542.03Phenazine methylsulfate
CAS :<p>Phenazine methylsulfate is anti-bacterial agents.</p>Formule :C14H14N2O4SDegré de pureté :97.67% - >99.99%Couleur et forme :Yellow CrystallineMasse moléculaire :306.34Z-DEVD-FMK
CAS :<p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>Formule :C30H41FN4O12Degré de pureté :96.19% - 99.69%Couleur et forme :SolidMasse moléculaire :668.66Euscaphic acid
CAS :<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Formule :C30H48O5Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :488.7GSK-923295
CAS :<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Formule :C32H38ClN5O4Degré de pureté :96.22% - 98.02%Couleur et forme :SolidMasse moléculaire :592.13CHIR-124
CAS :<p>CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM). It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.</p>Formule :C23H22ClN5ODegré de pureté :96.33% - 98.35%Couleur et forme :SolidMasse moléculaire :419.91WP1066
CAS :<p>WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.</p>Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22Quinidine sulfate dihydrate
CAS :<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Formule :C40H54N4O10SDegré de pureté :99.85%Couleur et forme :White To Light Yellow Crystal PowdeMasse moléculaire :782.9Perillyl alcohol
CAS :<p>Perillyl Alcohol, a monoterpene with antitumor properties, inhibits protein activation blocking cancer cell growth.</p>Formule :C10H16ODegré de pureté :97.36%Couleur et forme :SolidMasse moléculaire :152.23Asperosaponin VI
CAS :<p>Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.</p>Formule :C47H76O18Degré de pureté :97.15% - 99.79%Couleur et forme :SolidMasse moléculaire :929.1(ZE)-SU9516
CAS :<p>(ZE)-SU9516 is a selectively potent ATP-competitive inhibitor of CDKs.</p>Formule :C13H11N3O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :241.25Ginsenoside Rg6
CAS :<p>Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells</p>Formule :C42H70O12Degré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :767Rhapontin
CAS :<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>Formule :C21H24O9Degré de pureté :99% - 99.91%Couleur et forme :Light YellowMasse moléculaire :420.41Diclofenac Potassium
CAS :<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Formule :C14H10Cl2KNO2Degré de pureté :99.51%Couleur et forme :White To Yellowish Crystalline PowderMasse moléculaire :334.24Thalidomide-O-amido-PEG2-C2-NH2 TFA
CAS :<p>Thalidomide-based E3 ligase ligand-linker for PROTAC with PEG2 bridge; cereblon-targeted.</p>Formule :C23H27F3N4O10Degré de pureté :95.74% - 99%Couleur et forme :SolidMasse moléculaire :576.48CCPA
CAS :<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Formule :C15H20ClN5O4Degré de pureté :99.1%Couleur et forme :Off-White To Light Yellow SolidMasse moléculaire :369.8Fasentin
CAS :<p>Fasentin (N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide) is an inhibitor of GluT1.</p>Formule :C11H9ClF3NO2Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :279.64Aminopurvalanol A
CAS :<p>Aminopurvalanol A is a competitive, selective and cell-permeable inhibitor of cyclin-dependent kinase (CDK) that potently inhibits Cyclin A/cdk2, Cyclin B/cdk1</p>Formule :C19H26ClN7ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :403.91Mitoxantrone diacetate
CAS :<p>Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).</p>Formule :C26H36N4O10Couleur et forme :SolidMasse moléculaire :564.592ONO-8130
CAS :<p>ONO-8130 is an orally available antagonist of EP1 receptor.</p>Formule :C25H28N2O5S2Degré de pureté :97.82%Couleur et forme :SolidMasse moléculaire :500.63Apomine
CAS :<p>Apomine (SR-9223i) 是一种 HMG-CoA-还原酶抑制剂，可在体外促进骨髓瘤细胞的凋亡，并与体内骨髓瘤的调节有关。 Apomine 加速 3-羟基-3-甲基戊二酰-CoA 还原酶的降解并刺激低密度脂蛋白受体活性。 Apomine 通过下调 3-羟基-3-甲基戊二酰-CoA 还原酶来增强洛伐他汀对骨髓瘤细胞的抗肿瘤作用。</p>Formule :C28H52O7P2Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :562.664,5-Dicaffeoylquinic acid
CAS :<p>1.</p>Formule :C25H24O12Degré de pureté :98.86% - ≥95%Couleur et forme :SolidMasse moléculaire :516.45Fedratinib
CAS :Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.Formule :C27H36N6O3SDegré de pureté :97.31% - 99.96%Couleur et forme :SolidMasse moléculaire :524.68Chelerythrine
CAS :<p>1.</p>Formule :C21H18NO4Degré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :348.37OSU-T315
CAS :<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formule :C30H30F3N5ODegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :533.59Maduramicin ammonium
CAS :<p>Maduramicin ammonium (Maduramycin Ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E.</p>Formule :C47H83NO17Degré de pureté :99.83%Couleur et forme :White Crystalline PowderMasse moléculaire :934.20Dimethyl malonate
CAS :<p>Dimethyl Malonate is a Succinate Dehydrogenase inhibitor.</p>Formule :C5H8O4Degré de pureté :≥95%Couleur et forme :LiquidMasse moléculaire :132.11Itanapraced
CAS :<p>Itanapraced (CHF5074), a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).</p>Formule :C16H11Cl2FO2Degré de pureté :98% - 99.79%Couleur et forme :SolidMasse moléculaire :325.16Tofacitinib Citrate
CAS :<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Formule :C22H28N6O8Degré de pureté :99.19% - 99.75%Couleur et forme :SolidMasse moléculaire :504.49BML-277
CAS :<p>BML-277 (C 3742) is a selective checkpoint kinase 2 (Chk2) inhibitor.</p>Formule :C20H14ClN3O2Degré de pureté :98.03% - ≥95%Couleur et forme :Tan SolidMasse moléculaire :363.8Iproniazid
CAS :<p>Iproniazid is an irreversible monoamine oxidase inhibitor. It is used as an antidepressive agent.</p>Formule :C9H13N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :179.22Siremadlin
CAS :<p>Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.</p>Formule :C26H24Cl2N6O4Degré de pureté :99.30% - 99.76%Couleur et forme :SolidMasse moléculaire :555.41Diosgenin glucoside
CAS :<p>Diosgenin glucoside (Trillin) and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis</p>Formule :C33H52O8Degré de pureté :97.17% - 99.44%Couleur et forme :SolidMasse moléculaire :576.76NVP 231
CAS :<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Formule :C25H25N3O2SDegré de pureté :99.16% - ≥95%Couleur et forme :SolidMasse moléculaire :431.55LYN-1604 dihydrochloride
CAS :<p>LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Formule :C33H45Cl4N3O2Degré de pureté :98.95% - 99.92%Couleur et forme :SolidMasse moléculaire :657.54Meloxicam sodium
CAS :<p>Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].</p>Formule :C14H12N3NaO4S2Couleur et forme :SolidMasse moléculaire :373.383'-Hydroxypterostilbene
CAS :<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Formule :C16H16O4Degré de pureté :98.25% - 99.19%Couleur et forme :SolidMasse moléculaire :272.3UTL-5g
CAS :<p>UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.</p>Formule :C11H8Cl2N2O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :271.1Benzoylpaeoniflorin
CAS :<p>1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.</p>Formule :C30H32O12Degré de pureté :95.86% - 97.28%Couleur et forme :SolidMasse moléculaire :584.57Cinchonine monohydrochloride hydrate
CAS :<p>Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.</p>Formule :C19H25ClN2O2Couleur et forme :SolidMasse moléculaire :348.87TBHQ
CAS :<p>TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.</p>Formule :C10H14O2Degré de pureté :99.17% - 99.53%Couleur et forme :White Solid PowderMasse moléculaire :166.22Ulinastatin
CAS :<p>Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.</p>Formule :C13H16O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.10994Droxinostat
CAS :<p>Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3</p>Formule :C11H14ClNO3Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :243.69JX06
CAS :<p>JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.</p>Formule :C10H16N2O2S4Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :324.51Ginsenoside Rh2
CAS :<p>Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.</p>Formule :C36H62O8Degré de pureté :99.20% - 99.76%Couleur et forme :White PowderMasse moléculaire :622.87SZL P1-41
CAS :<p>SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.</p>Formule :C24H24N2O3SDegré de pureté :99.60% - 99.87%Couleur et forme :SolidMasse moléculaire :420.52Ginsenoside F2
CAS :<p>Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.</p>Formule :C42H72O13Degré de pureté :99.04% - 99.3%Couleur et forme :SolidMasse moléculaire :785.01RG7112
CAS :<p>RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.</p>Formule :C38H48Cl2N4O4SDegré de pureté :99.66% - 99.9%Couleur et forme :SolidMasse moléculaire :727.78Pyrogallol
CAS :<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Formule :C6H6O3Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :126.11HA14-1
CAS :<p>HA14-1, a Bcl-2/Bcl-XL antagonist, is a non-peptidic ligand of a Bcl-2 surface pocket (IC50: ~9 μM).</p>Formule :C17H17BrN2O5Degré de pureté :95.07% - 98%Couleur et forme :SolidMasse moléculaire :409.23Piperazine Erastin
CAS :<p>Piperazine erastin is an analog of erastin. It causes an iron-dependent form of non-apoptotic cell death termed ferroptosis.</p>Formule :C35H41ClN6O4Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :645.19Euphorbia Factor L2
CAS :<p>Euphorbia Factor L2 alleviates lipopolysaccharide-induced acute lung injury and inflammation through inhibits NF-κB activation.</p>Formule :C38H42O9Degré de pureté :99.53% - 99.96%Couleur et forme :SolidMasse moléculaire :642.738-Bromo-cAMP sodium salt
CAS :<p>8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.</p>Formule :C10H10BrN5NaO6PDegré de pureté :98% - 99.94%Couleur et forme :Off-White PowderMasse moléculaire :430.08OTS514
CAS :<p>OTS514 (OTS514 Hydrochloride) is a potent TOPK inhibitor.</p>Formule :C21H20N2O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :364.46Nobiletin
CAS :<p>Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.</p>Formule :C21H22O8Degré de pureté :98.65% - 99.76%Couleur et forme :SolidMasse moléculaire :402.39Cinobufagin
CAS :<p>Cinobufagin (Cinobufagine) is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.</p>Formule :C26H34O6Degré de pureté :97.77% - 99.97%Couleur et forme :SolidMasse moléculaire :442.54C5 Lenalidomide
CAS :<p>C5 Lenalidomide is an chemical weith inconclusive biological activity.</p>Formule :C13H13N3O3Degré de pureté :99.4%Couleur et forme :SolidMasse moléculaire :259.26Kinetin riboside
CAS :<p>Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)</p>Formule :C15H17N5O5Degré de pureté :98.17%Couleur et forme :White SolidMasse moléculaire :347.33PF-4989216
CAS :<p>PF-4989216 is a potent and selective PI3K inhibitor with IC50 of 2 nM, 142 nM, 65 nM, 1 nM, and 110 nM for p110α, p110β, p110γ, p110δ, and VPS34, respectively.</p>Formule :C18H13FN6OSDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :380.4PD173955
CAS :<p>PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR and</p>Formule :C21H16Cl2N4OSDegré de pureté :98.52% - 98.99%Couleur et forme :SolidMasse moléculaire :443.35Tauroursodeoxycholate sodium
CAS :<p>Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.</p>Formule :C26H44NNaO6SDegré de pureté :97.90%Couleur et forme :SolidMasse moléculaire :521.69Bay 11-7085
CAS :<p>Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).</p>Formule :C13H15NO2SDegré de pureté :99.76% - 99.94%Couleur et forme :White SolidMasse moléculaire :249.33Pyrazoloadenine
CAS :<p>Pyrazoloadenine (4-Aminopyrazolo[3,4-d]pyrimidine) is the inhibitor of human xanthine oxidase.</p>Formule :C5H5N5Degré de pureté :99.02%Couleur et forme :Beige PowderMasse moléculaire :135.13Dacomitinib
CAS :<p>Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.</p>Formule :C24H25ClFN5O2Degré de pureté :99.4% - 99.72%Couleur et forme :SolidMasse moléculaire :469.94BDA-366
CAS :<p>BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its</p>Formule :C24H29N3O4Degré de pureté :98.61%Couleur et forme :SoildMasse moléculaire :423.5Fenoldopam mesylate
CAS :<p>Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties.</p>Formule :C16H16ClNO3·CH4O3SDegré de pureté :99.19%Couleur et forme :SolidMasse moléculaire :401.86Flupentixol dihydrochloride
CAS :<p>Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.</p>Formule :C23H27Cl2F3N2OSDegré de pureté :98.76% - >99.99%Couleur et forme :White Or Off-White SolidMasse moléculaire :507.43Shield-1
CAS :<p>Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.</p>Formule :C42H56N2O10Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :748.9S-99
CAS :<p>S-99 is a high purity chemical that targets ASK and is important for Immunology, Inflammation, Cancer research.</p>Formule :C16H15F3N6ODegré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :364.33LCL161
CAS :<p>LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.</p>Formule :C26H33FN4O3SDegré de pureté :99.13% - 99.87%Couleur et forme :SolidMasse moléculaire :500.63ABT-737
CAS :<p>ABT-737 is a BH3 mimetic and an inhibitor of Bcl-2, Bcl-xL, and Bcl-w. ABT-737 exhibits antitumor activity and anti-aging activity. Cost-effective and quality-assured.</p>Formule :C42H45ClN6O5S2Degré de pureté :98.15% - >99.99%Couleur et forme :SolidMasse moléculaire :813.43Mocetinostat
CAS :<p>Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.</p>Formule :C23H20N6ODegré de pureté :99% - 99.21%Couleur et forme :SolidMasse moléculaire :396.44Suberoyl bis-hydroxamic acid
CAS :<p>SBHA is an HDAC inhibitor, an enzyme key to transcription, cell cycle, and development.</p>Formule :C8H16N2O4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :204.22RGX-202
CAS :<p>RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.</p>Formule :C4H9N3O2Degré de pureté :99.67% - 99.8%Couleur et forme :SolidMasse moléculaire :131.13tubuloside B
CAS :<p>Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.</p>Formule :C31H38O16Degré de pureté :97.59% - 99.72%Couleur et forme :SolidMasse moléculaire :666.62Neobavaisoflavone
CAS :<p>Neobavaisoflavone: DNA polymerase inhibitor, potential for treating bone loss, anti-inflammatory, reduces ROS, RNS, cytokines in macrophages.</p>Formule :C20H18O4Degré de pureté :99.31% - 99.87%Couleur et forme :SolidMasse moléculaire :322.35CI-1040
CAS :<p>CI-1040 (PD 184352) (PD184352) is an ATP non-competitive MEK1/2 inhibitor (IC50: 17 nM).</p>Formule :C17H14ClF2IN2O2Degré de pureté :99.64%Couleur et forme :Off-White To Pale Beige SolidMasse moléculaire :478.66Tetramethylcurcumin
CAS :<p>Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also</p>Formule :C25H28O6Degré de pureté :97.69% - 99.94%Couleur et forme :SolidMasse moléculaire :424.49Trigonelline
CAS :<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Formule :C7H7NO2Degré de pureté :97.585% - 99.49%Couleur et forme :Prisms Aqueous From Alcohol + Water SolidMasse moléculaire :137.143BDO
CAS :<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Formule :C18H17NO5Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :327.33Ibandronate sodium monohydrate
CAS :<p>Ibandronate sodium monohydrate (BM-210955) is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.</p>Formule :C9H24NNaO8P2Degré de pureté :99.62%Couleur et forme :White Crystalline PowderMasse moléculaire :359.23Obatoclax Mesylate
CAS :<p>Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and</p>Formule :C20H19N3O·CH4O3SDegré de pureté :99.58% - 99.88%Couleur et forme :SolidMasse moléculaire :413.49TASIN-1
CAS :<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Formule :C18H28N2O3SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :352.49AG1024
CAS :<p>AG1024 (Tyrphostin) suppresses IGF-1R autophosphorylation(IC50=7 μM), and is less potent for IR(IC50=57 μM).</p>Formule :C14H13BrN2ODegré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :305.17Tubeimoside I
CAS :<p>Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).</p>Formule :C63H98O29Degré de pureté :98.89% - 99.94%Couleur et forme :SolidMasse moléculaire :1319.43CHR-6494 TFA
CAS :<p>CHR-6494 TFA: potent haspin inhibitor (IC50=2 nM), blocks H3T3 phosphorylation, triggers apoptosis in cancer cells. Used for cancer research.</p>Formule :C18H17F3N6O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :406.36INH6
CAS :<p>INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment.</p>Formule :C19H18N2OSDegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :322.42Tazemetostat
CAS :<p>Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.</p>Formule :C34H44N4O4Degré de pureté :98.24% - ≥95%Couleur et forme :SolidMasse moléculaire :572.74Millepachine
CAS :<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Formule :C22H22O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :350.41WHI-P154
CAS :<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Formule :C16H14BrN3O3Degré de pureté :98% - 99.67%Couleur et forme :SolidMasse moléculaire :376.2Domatinostat
CAS :<p>Domatinostat (4SC202) is a selective class I HDAC inhibitor. Domatinostat also displays inhibitory activity against Lysine specific demethylase 1 (LSD1).</p>Formule :C23H21N5O3SDegré de pureté :99.57% - 99.74%Couleur et forme :SolidMasse moléculaire :447.51MPTP hydrochloride
CAS :<p>MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability.</p>Formule :C12H16ClNDegré de pureté :96.35% - >99.99%Couleur et forme :SolidMasse moléculaire :209.72Brevilin A
CAS :<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Formule :C20H26O5Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :346.427,8-Dihydroxyflavone
CAS :<p>7,8-Dihydroxyflavone (7,8-DHF) is a naturally-occurring flavone and exist in Tridax procumbens, Godmania aesculifolia, and primula tree leaves.</p>Formule :C15H10O4Degré de pureté :98.48% - 99.81%Couleur et forme :SolidMasse moléculaire :254.24VR23
CAS :<p>VR23: Potent proteasome inhibitor; IC50: 1 nM trypsin, 50-100 nM chymotrypsin, 3 μM caspase-like.</p>Formule :C19H16ClN5O6SDegré de pureté :98.99% - 99.22%Couleur et forme :SolidMasse moléculaire :477.88Choline
CAS :<p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>Formule :C5H15NO2Degré de pureté :99.97% - ≥98%Couleur et forme :LiquidMasse moléculaire :121.18UNC1215
CAS :<p>UNC1215, a potent MBT antagonist, targets L3MBTL3 with high selectivity (IC50: 40 nM, Kd: 120 nM, 50x versus MBT family).</p>Formule :C32H43N5O2Degré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :529.72(S)-crizotinib
CAS :<p>(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.</p>Formule :C21H22Cl2FN5ODegré de pureté :98.52% - 99.47%Couleur et forme :SolidMasse moléculaire :450.34Sodium dichloroacetate
CAS :<p>Sodium dichloroacetate (BCA) inhibits PDK (IC50: 183 μM PDK2, 80 μM PDK4), triggers cancer cell apoptosis, and impedes tumor growth.</p>Formule :C2HCl2NaO2Degré de pureté :99.32% - 99.87%Couleur et forme :White PowderMasse moléculaire :150.92McMMAF
CAS :<p>McMMAF is a protective group-conjugated MMAF.</p>Formule :C49H76N6O11Degré de pureté :99.65% - >99.99%Couleur et forme :SolidMasse moléculaire :925.16Nerol
CAS :<p>Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias</p>Formule :C10H18ODegré de pureté :98.59%Couleur et forme :Colorless Oily Liquid LiquidMasse moléculaire :154.25Caffeic Acid Phenethyl Ester
CAS :<p>CAPE, in propolis, blocks NF-kappa B, suppresses p70S6K/Akt pathways, and inhibits PDGF, aiding in cancer protection and immune modulation.</p>Formule :C17H16O4Degré de pureté :99.18% - 99.35%Couleur et forme :Less Transparent Liquid Colorless Transparent LiquidMasse moléculaire :284.31NADPH tetrasodium salt
CAS :<p>NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of</p>Formule :C21H26N7Na4O17P3Degré de pureté :97.15% - >99.99%Couleur et forme :SolidMasse moléculaire :833.35Dienogest
CAS :<p>Dienogest (STS 557), an oral 4th-gen progestogen, is used in hormone therapy and contraception with antiandrogenic effects.</p>Formule :C20H25NO2Degré de pureté :98% - 99.43%Couleur et forme :Pale Yellow SolidMasse moléculaire :311.42Ricolinostat
CAS :<p>Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.</p>Formule :C24H27N5O3Degré de pureté :97.17% - 99.76%Couleur et forme :SolidMasse moléculaire :433.5Deferitrin
CAS :<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Formule :C11H11NO4SDegré de pureté :98.71%Couleur et forme :SolidMasse moléculaire :253.27Vistusertib
CAS :<p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>Formule :C25H30N6O3Degré de pureté :97.08% - 99.06%Couleur et forme :SolidMasse moléculaire :462.54Vesatolimod
CAS :<p>Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.</p>Formule :C22H30N6O2Degré de pureté :97.46% - 99.03%Couleur et forme :SolidMasse moléculaire :410.51CDDO-Im
CAS :<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Formule :C34H43N3O3Degré de pureté :98.3% - 99.61%Couleur et forme :SolidMasse moléculaire :541.72Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS :<p>Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.</p>Formule :C15H16ClN3O5Degré de pureté :98.56%Couleur et forme :SolidMasse moléculaire :353.76Sodium Demethylcantharidate
CAS :<p>Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.</p>Formule :C8H9O5·NaDegré de pureté :99.66% - ≥98%Couleur et forme :SolidMasse moléculaire :208.14HBX 41108
CAS :<p>HBX 41108: non-competitive, reversible USP7 inhibitor; IC50: 424nM; blocks USP7-p53 deubiquitination; IC50: 0.8μM.</p>Formule :C13H3ClN4ODegré de pureté :95.63%Couleur et forme :SolidMasse moléculaire :266.64IC261
CAS :<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Formule :C18H17NO4Degré de pureté :99.45% - 99.91%Couleur et forme :SolidMasse moléculaire :311.33Thonningianin A
CAS :<p>Thonningianin A: an anti-cancer compound with antioxidant effects, GST inhibitor, and radical scavenger.</p>Formule :C42H34O21Degré de pureté :98.37% - 99.94%Couleur et forme :SolidMasse moléculaire :874.71Sertaconazole
CAS :<p>Sertaconazole is a broad-spectrum antifungal.</p>Formule :C20H15Cl3N2OSDegré de pureté :99.483%Couleur et forme :SolidMasse moléculaire :437.77BAY 61-3606 HCl
CAS :<p>BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.</p>Formule :C20H19ClN6O3Couleur et forme :SolidMasse moléculaire :426.86FB23-2
CAS :<p>FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).</p>Formule :C18H15Cl2N3O3Degré de pureté :97.29% - ≥95%Couleur et forme :SolidMasse moléculaire :392.24EPI-001
CAS :<p>EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.</p>Formule :C21H27ClO5Degré de pureté :99% - 99.67%Couleur et forme :SolidMasse moléculaire :394.89Thalidomide-O-amido-C6-NH2 TFA
CAS :<p>Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-based</p>Formule :C46H53F6N8O16Degré de pureté :95.16%Couleur et forme :SolidMasse moléculaire :1087.95ICCB280
CAS :<p>ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome</p>Formule :C23H18N2O4Degré de pureté :98.04%Couleur et forme :SolidMasse moléculaire :386.4Evocarpine
CAS :<p>Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.</p>Formule :C23H33NODegré de pureté :99.77% - 99.819%Couleur et forme :SolidMasse moléculaire :339.51HLCL-61 hydrochloride
CAS :<p>HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.</p>Formule :C23H24N2O·ClHDegré de pureté :99.88% - 99.95%Couleur et forme :SolidMasse moléculaire :380.91BTZO-1
CAS :<p>BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.</p>Formule :C13H8N2OSDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :240.28EF24
CAS :<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Formule :C19H15F2NODegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :311.33Penicillic acid
CAS :<p>Penicillic acid, a mycotoxin from Aspergillus/Penicillium, blocks Fas ligand apoptosis and is cytotoxic to rat lung macrophages.</p>Formule :C8H10O4Degré de pureté :98%Couleur et forme :Needles From Petroleum Ether Slight Yellow PowderMasse moléculaire :170.16Bacopaside II
CAS :<p>Bacopaside II is a potential anti-angiogenic agent, it can reduce endothelial cell migration and tubulogenesis and induce apoptosis.</p>Formule :C47H76O18Degré de pureté :98.14% - 99.86%Couleur et forme :SolidMasse moléculaire :929.1S63845
CAS :<p>S63845 is a selective myeloid leukemia 1（MCL1) inhibitor that binds to human MCL1 with a Kd of 0.19 nM.Cost-effective and quality-assured.</p>Formule :C39H37ClF4N6O6SDegré de pureté :97.7% - ≥98%Couleur et forme :SolidMasse moléculaire :829.26Rigosertib
CAS :<p>Rigosertib, a multi-kinase inhibitor targeting PLK1 (IC50: 9 nM), induces apoptosis and G2/M arrest by disrupting PI3K/Akt.</p>Formule :C21H25NO8SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :451.49MK-8745
CAS :<p>MK-8745 is a potent and selective Aurora A inhibitor.</p>Formule :C20H19ClFN5OSDegré de pureté :99.09% - 99.79%Couleur et forme :SolidMasse moléculaire :431.91
