Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5599 produits trouvés pour "Apoptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Acenocoumarol
CAS :<p>Acenocoumarol is a Vitamin K antagonist and used as an anticoagulant.</p>Formule :C19H15NO6Degré de pureté :99.95%Couleur et forme :Crystals SolidMasse moléculaire :353.33Calcium dobesilate
CAS :Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.Formule :C6H5O5SCa0Degré de pureté :98.39%Couleur et forme :White Or Almost PowderMasse moléculaire :229.2DAPT
CAS :<p>DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.</p>Formule :C23H26F2N2O4Degré de pureté :98.06% - 99.81%Couleur et forme :White SolidMasse moléculaire :432.46UAMC-3203
CAS :<p>UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).</p>Formule :C25H37N5O2SDegré de pureté :97.052% - 99.72%Couleur et forme :SolidMasse moléculaire :471.66JG-98
CAS :<p>JG-98 is an allosteric Hsp70 inhibitor, displays high active against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50s: 0.4/0.7 μM).</p>Formule :C24H21Cl2N3OS3Degré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :534.53ENMD-1068 hydrochloride
CAS :<p>ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.</p>Formule :C15H30ClN3O2Couleur et forme :SolidMasse moléculaire :319.87BI-3802
CAS :<p>BI-3802, a highly potent BCL6 degrader, targets and inhibits the Bric-à-brac (BTB) domain of BCL6, exhibiting an IC50 value of ≤3 nM.</p>Formule :C24H29ClN6O3Degré de pureté :97.93% - 98.58%Couleur et forme :SolidMasse moléculaire :484.98Glycochenodeoxycholic acid sodium salt
CAS :<p>GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.</p>Formule :C26H42NNaO5Degré de pureté :95.48% - 99.82%Couleur et forme :SolidMasse moléculaire :471.61Flavokawain A
CAS :<p>NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.</p>Formule :C18H18O5Degré de pureté :97.1% - 99.72%Couleur et forme :SolidMasse moléculaire :314.332Vesatolimod
CAS :<p>Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.</p>Formule :C22H30N6O2Degré de pureté :97.46% - 99.03%Couleur et forme :SolidMasse moléculaire :410.51Sulforaphene
CAS :<p>Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.</p>Formule :C6H9NOS2Degré de pureté :97.55% - 99.19%Couleur et forme :Slightly Yellowish LiquidMasse moléculaire :175.27IMM-01
CAS :<p>IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actin</p>Formule :C12H17N3O2SDegré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :267.35IC261
CAS :<p>IC261 (SU-5607) is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50 of IC261 for CK1 was 16 μM and for Cdk5 is 4.5 mM.</p>Formule :C18H17NO4Degré de pureté :99.45% - 99.91%Couleur et forme :SolidMasse moléculaire :311.33Delanzomib
CAS :<p>Delanzomib (CEP-18770) is an oral proteasome inhibitor with an IC50 of 3.8 nM, targeting chymotrypsin-like activity with minimal effect on other activities.</p>Formule :C21H28BN3O5Degré de pureté :95.52% - 99.46%Couleur et forme :SolidMasse moléculaire :413.28NSC 3852
CAS :<p>NSC 3852 is a potent inhibitor of histone deacetylase.</p>Formule :C9H6N2O2Degré de pureté :99.64%Couleur et forme :Slightly Yellow To Yellow-Green PowderMasse moléculaire :174.16Pyrogallol
CAS :<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Formule :C6H6O3Degré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :126.11FX1
CAS :<p>FX1 is an effective and selective BCL6 inhibitor (IC50: 35 μM).</p>Formule :C14H9ClN2O4S2Degré de pureté :97.59%Couleur et forme :SolidMasse moléculaire :368.82Gardenin B
CAS :<p>Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .</p>Formule :C19H18O7Degré de pureté :98.80% - 99.74%Couleur et forme :SolidMasse moléculaire :358.34Didanosine
CAS :<p>Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM).</p>Formule :C10H12N4O3Degré de pureté :99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :236.23Tenovin-6 Hydrochloride
CAS :<p>Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.</p>Formule :C25H35ClN4O2SDegré de pureté :99.36%Couleur et forme :SolidMasse moléculaire :491.09Salvigenin
CAS :<p>Salvigenin is a potent hMAO-A inhibitor, has neuroprotective, antitumor and immunomodulatory effects.</p>Formule :C18H16O6Degré de pureté :99.17% - 99.78%Couleur et forme :SolidMasse moléculaire :328.32Navtemadlin
CAS :<p>Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.</p>Formule :C28H35Cl2NO5SDegré de pureté :95.55% - 99.08%Couleur et forme :SolidMasse moléculaire :568.55Garcinol
CAS :<p>Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).</p>Formule :C38H50O6Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :602.8Toddaculin
CAS :<p>Toddaculine may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the</p>Formule :C16H18O4Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :274.31AZD3759 hydrochloride
CAS :<p>AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.</p>Formule :C22H24Cl2FN5O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :496.36Zoledronic acid monohydrate
CAS :<p>Zoledronic acid monohydrate (CGP 42446) is a synthetic imidazole bisphosphonate analog with anti-bone-resorption activity.</p>Formule :C5H12N2O8P2Degré de pureté :99.91%Couleur et forme :White To Off-White PowderMasse moléculaire :290.1Ciprofloxacin hydrochloride monohydrate
CAS :<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Formule :C17H21ClFN3O4Degré de pureté :99.23% - 99.85%Couleur et forme :White Or Yellowish Crystalline PowderMasse moléculaire :385.82Isoalantolactone
CAS :<p>Isoalantolactone (Isohelenin), isolated from Inula spp., can inhibit the growth of several types of Y cells.</p>Formule :C15H20O2Degré de pureté :99.75% - 99.94%Couleur et forme :SolidMasse moléculaire :232.323-O-Methylgallic acid
CAS :<p>3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and</p>Formule :C8H8O5Degré de pureté :99.56%Couleur et forme :SolidMasse moléculaire :184.15NVP 231
CAS :<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Formule :C25H25N3O2SDegré de pureté :99.16% - ≥95%Couleur et forme :SolidMasse moléculaire :431.55SZL P1-41
CAS :<p>SZL P1-41 inhibits Skp2, blocks complex formation, and halts ubiquitination, promoting cell senescence, reducing glycolysis, and exhibiting antitumor effects.</p>Formule :C24H24N2O3SDegré de pureté :99.60% - 99.87%Couleur et forme :SolidMasse moléculaire :420.52Pifithrin-β hydrobromide
CAS :<p>Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis.</p>Formule :C16H17BrN2SDegré de pureté :99.24% - 99.74%Couleur et forme :SolidMasse moléculaire :349.29Lithocholic acid
CAS :<p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>Formule :C24H40O3Degré de pureté :99.69% - 99.93%Couleur et forme :Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Masse moléculaire :376.57PKD-IN-1 dihydrochloride (956121-30-5 free base)
CAS :<p>CRT0066101 dihydrochloride is an inhibitor of PKD.</p>Formule :C18H21Cl3N4ODegré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :415.75EGFR-IN-12
CAS :<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Formule :C21H18F3N5ODegré de pureté :98.3% - 99.76%Couleur et forme :SolidMasse moléculaire :413.4Suramin Sodium Salt
CAS :<p>Suramin Sodium Salt (BAY-205) is a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors.</p>Formule :C51H34N6Na6O23S6Degré de pureté :97.47% - 99.97%Couleur et forme :WhiteMasse moléculaire :1429.15Epibrassinolide
CAS :<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Formule :C28H48O6Degré de pureté :97.57% - 98.11%Couleur et forme :SolidMasse moléculaire :480.68Cabozantinib S-malate
CAS :<p>Cabozantinib S-malate (XL184) is the salt form of cabozantinib, an orally bioavailable, small molecule RTK inhibitor with potential antineoplastic activity.</p>Formule :C32H30FN3O10Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :635.59Ipatasertib
CAS :<p>Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.</p>Formule :C24H32ClN5O2Degré de pureté :98.28% - 99.21%Couleur et forme :SolidMasse moléculaire :458ZZW-115 hydrochloride
CAS :<p>ZZW-115 hydrochloride inhibits the activity of NUPR1.</p>Formule :C24H34Cl3F3N4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :573.97Chromium picolinate
CAS :<p>Chromium picolinate causes DNA damage and mutation. It is an activator of p38.</p>Formule :C18H12CrN3O6Degré de pureté :99.64%Couleur et forme :Violet-Red Crystalline PowderMasse moléculaire :418.30RO8994
CAS :<p>RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).</p>Formule :C31H31Cl2FN4O4Degré de pureté :99.31% - 99.44%Couleur et forme :SolidMasse moléculaire :613.51Ceftiofur
CAS :<p>Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.</p>Formule :C19H17N5O7S3Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :523.56SGI-1027
CAS :<p>SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).</p>Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52Apocynin
CAS :<p>Apocynin (NSC 2146) is a specific NADPH-oxidase inhibitor (IC50: 10 μM).</p>Formule :C9H10O3Degré de pureté :99.71% - 99.98%Couleur et forme :Yellowish To Brown PowderMasse moléculaire :166.17BMS-536924
CAS :<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Formule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96DC260126
CAS :<p>DC260126 is a small-molecule antagonist of FFA1 (GPR40)</p>Formule :C16H18FNO2SDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :307.38α-Hederin
CAS :<p>Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.</p>Formule :C41H66O12Degré de pureté :99.44% - 99.89%Couleur et forme :SolidMasse moléculaire :750.96D-Saccharic acid 1,4-lactone hydrate
CAS :<p>D-Saccharic acid 1,4-lactone hydrate inhibits β-glucuronidase (IC50=48.4 μM); has anticarcinogenic, detoxifying, antioxidant traits.</p>Formule :C17H20ClN3ODegré de pureté :99.49% - ≥98%Couleur et forme :SolidMasse moléculaire :317.81Quisinostat
CAS :<p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47
