Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(126 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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ML385
CAS :ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Formule :C29H25N3O4SDegré de pureté :98.08% - >99.99%Couleur et forme :SolidMasse moléculaire :511.59Ref: TM-T4360
5mg49,00€10mg74,00€25mg144,00€50mg230,00€100mg356,00€200mg532,00€500mg852,00€1mL*10mM (DMSO)56,00€Suberoyl bis-hydroxamic acid
CAS :SBHA is an HDAC inhibitor, an enzyme key to transcription, cell cycle, and development.Formule :C8H16N2O4Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :204.224,5-Dicaffeoylquinic acid
CAS :1.Formule :C25H24O12Degré de pureté :98.86% - ≥95%Couleur et forme :SolidMasse moléculaire :516.45Ref: TM-T2S1158
1mg43,00€5mg84,00€10mg109,00€25mg172,00€50mg250,00€100mg326,00€200mg522,00€1mL*10mM (DMSO)102,00€Tauroursodeoxycholate dihydrate
CAS :Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a bile acid that reduces Caspase-3, Caspase-12, ERK, reducing endoplasmic reticulum stress mediated death.Formule :C26H49NO8SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :535.73Alisertib
CAS :Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is >200-fold higher for Aurora A than Aurora B.Formule :C27H20ClFN4O4Degré de pureté :98.31% - >99.99%Couleur et forme :SolidMasse moléculaire :518.92Ref: TM-T2241
5mg52,00€10mg92,00€25mg146,00€50mg215,00€100mg334,00€200mg430,00€500mg705,00€1mL*10mM (DMSO)59,00€SR-318
CAS :SR-318 inhibits TNF-α (IC50=283 nM), selectively targets p38 MAPK: IC50 of 5nM (p38α), 32nM (p38β), 6.11μM (p38α/β).Formule :C27H33N5O2Degré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :459.58Ref: TM-T12997
2mg35,00€5mg55,00€10mg92,00€25mg166,00€50mg259,00€100mg371,00€200mg533,00€1mL*10mM (DMSO)55,00€Mitoxantrone
CAS :Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.Formule :C22H28N4O6Degré de pureté :96.29% - 98.74%Couleur et forme :Blue PowderMasse moléculaire :444.48Obacunone
CAS :Obacunone: cytotoxic to prostate cells, anti-S. Typhimurium, may inhibit breast cancer and aromatase, trigger apoptosis.Formule :C26H30O7Degré de pureté :98% - ≥95%Couleur et forme :White PowderMasse moléculaire :454.51Ref: TM-T3390
2mg35,00€5mg48,00€10mg70,00€25mg104,00€50mg153,00€100mg216,00€200mg320,00€1mL*10mM (DMSO)52,00€Oxibendazole
CAS :Oxibendazole: a benzimidazole antiparasitic for horses and pets against various worms.Formule :C12H15N3O3Degré de pureté :99.3% - 99.88%Couleur et forme :Crystalline SolidMasse moléculaire :249.27TCPOBOP
CAS :TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.Formule :C16H8Cl4N2O2Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :402.06Sulforaphene
CAS :Sulforaphene, from radish seeds, aids cancer cell apoptosis and inhibits migration; has an ED50 for velvetleaf at ~2x10^-4 M.Formule :C6H9NOS2Degré de pureté :97.55% - 99.67%Couleur et forme :Slightly Yellowish LiquidMasse moléculaire :175.27Ref: TM-TL0016
1mg34,00€2mg46,00€5mg66,00€10mg92,00€25mg167,00€50mg241,00€100mg359,00€200mg525,00€1mL*10mM (DMSO)65,00€Z-YVAD-FMK
CAS :AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.Formule :C31H39FN4O9Degré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :630.66GSK481
CAS :GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.Formule :C21H19N3O4Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :377.39GSK2982772
CAS :GSK2982772 is an inhibitor of receptor interacting serine/threonine kinase 1 (RIPK1)with IC50 values of 16 nM and 20 nM for human and monkey RIP1, respectively.Formule :C20H19N5O3Degré de pureté :99.27% - 99.31%Couleur et forme :SolidMasse moléculaire :377.4GS-444217
CAS :GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).Formule :C23H21N7ODegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :411.46Levistolide A
CAS :1. Levistolide A (Diligustilide) inhibits liver fibrosis and angiogenesis.Formule :C24H28O4Degré de pureté :98.93% - 99.22%Couleur et forme :SolidMasse moléculaire :380.48Ref: TM-T6S1292
1mg34,00€5mg65,00€10mg94,00€25mg137,00€50mg193,00€100mg286,00€200mg423,00€1mL*10mM (DMSO)73,00€GSK3179106
CAS :GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nMFormule :C22H21F4N3O4Degré de pureté :99.8% - 99.90%Couleur et forme :SolidMasse moléculaire :467.41GSK547
CAS :GSK547 (GSK'547) is a highly selective and potent inhibitor of RIP1 kinase,inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer.Formule :C20H18F2N6ODegré de pureté :99.17%Couleur et forme :SolidMasse moléculaire :396.39Chromium picolinate
CAS :Chromium picolinate causes DNA damage and mutation. It is an activator of p38.Formule :C18H12CrN3O6Degré de pureté :99.64%Couleur et forme :Violet-Red Crystalline PowderMasse moléculaire :418.30Barasertib-HQPA
CAS :Barasertib-HQPA (AZD2811) is a highly selective Aurora B inhibitor (IC50: 0.37 nM) and demonstrates ~3,700-fold greater selectivity than Aurora A.
Formule :C26H30FN7O3Degré de pureté :98.43% - 99.29%Couleur et forme :SolidMasse moléculaire :507.56CA-5f
CAS :CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion.Formule :C24H24N2O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :388.46Flavokawain C
CAS :Flavokawain C: natural chalcone from Kava with potential as a colon cancer drug.Formule :C17H16O5Degré de pureté :99.94% - ≥95%Couleur et forme :SolidMasse moléculaire :300.31Garcinol
CAS :Garcinol: inhibits HATs/PCAF (IC50=7/5 μM), anti-inflammatory, anti-cancer, anti-cholinesterase (AChE IC50=0.66 μM, BChE IC50=7.39 μM).Formule :C38H50O6Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :602.8Scopoletin
CAS :Scopoletin (Esculetin 6-methyl ether) is a plant growth factor derived from the root of Scopolia carniolica, inhibits of acetylcholinesterase (AChE).Formule :C10H8O4Degré de pureté :97.06% - 99.88%Couleur et forme :Yellow To Beige Crystalline PowderMasse moléculaire :192.17Cucurbitacin B
CAS :Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.Formule :C32H46O8Degré de pureté :97.1% - 99.93%Couleur et forme :SolidMasse moléculaire :558.70ZZW-115 hydrochloride
CAS :ZZW-115 hydrochloride inhibits the activity of NUPR1.Formule :C24H34Cl3F3N4SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :573.97Ref: TM-T9465
1mg87,00€5mg178,00€10mg281,00€25mg480,00€50mg692,00€100mg973,00€500mg1.945,00€1mL*10mM (DMSO)233,00€Kinsenoside
CAS :Kinsenoside ((+)-Kinsenoside) shows significant antihepatotoxic, and anti-inflammatory activities.Formule :C10H16O8Degré de pureté :99.2% - 99.92%Couleur et forme :SolidMasse moléculaire :264.23Ipatasertib
CAS :Ipatasertib (GDC-0068) is a selective, ATP-competitive pan-Akt inhibitor that can lead to p53-independent PUMA activation.Cost-effective and quality-assured.Formule :C24H32ClN5O2Degré de pureté :98.28% - 99.79%Couleur et forme :SolidMasse moléculaire :458AZD-7648
CAS :AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4Ref: TM-T7122
1mg38,00€5mg84,00€10mg113,00€25mg177,00€50mg295,00€100mg447,00€200mg650,00€1mL*10mM (DMSO)93,00€GSK2983559 active metabolite
CAS :GSK2983559 active metabolite (RIPK2-IN-1) is a potent, selective receptor-interacting protein-2 (RIP2) kinase inhibitor.Formule :C21H22N4O4S2Degré de pureté :97.07% - 99.57%Couleur et forme :SolidMasse moléculaire :458.554-Methyldaphnetin
CAS :4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.Formule :C10H8O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :192.17Valepotriate
CAS :Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.Formule :C22H30O8Degré de pureté :97.29% - 99.90%Couleur et forme :SolidMasse moléculaire :422.47BMS-8
CAS :BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly to PD-L1 and inducing the formation of PD-L1 homodimers.Formule :C27H28BrNO3Degré de pureté :98.88%Couleur et forme :SolidMasse moléculaire :494.42Ref: TM-T26859
1mg37,00€5mg79,00€10mg124,00€25mg222,00€50mg340,00€100mg505,00€200mg705,00€1mL*10mM (DMSO)86,00€BMS-1001
CAS :BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).Formule :C35H34N2O7Degré de pureté :98.43%Couleur et forme :SolidMasse moléculaire :594.7Ref: TM-T8470
1mg58,00€5mg124,00€10mg177,00€25mg299,00€50mg424,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)172,00€SP600125
CAS :SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFormule :C14H8N2ODegré de pureté :97.63% - 99.82%Couleur et forme :SolidMasse moléculaire :220.23Denosumab
CAS :Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligandFormule :C6404H9912N1724O2004S50Degré de pureté :95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Couleur et forme :LiquidMasse moléculaire :144.71 kDaβ-Elemonic Acid
CAS :β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.Formule :C30H46O3Degré de pureté :99.61% - 99.8%Couleur et forme :SolidMasse moléculaire :454.68Ref: TM-T2S0618
1mg35,00€5mg75,00€10mg110,00€25mg192,00€50mg286,00€100mg425,00€200mg612,00€1mL*10mM (DMSO)84,00€Mimosine
CAS :L-Mimosine (Leucenol) is an antineoplastic alanine-substituted pyridine derivative isolated from Leucena glauca and acts as an iron chelator.Formule :C8H10N2O4Degré de pureté :99.2% - 99.84%Couleur et forme :Crystals From Water SolidMasse moléculaire :198.18Onatasertib
CAS :Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formule :C21H27N5O3Degré de pureté :99.14% - 99.93%Couleur et forme :SolidMasse moléculaire :397.47Spautin-1
CAS :Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Formule :C15H11F2N3Degré de pureté :97.69% - 98.99%Couleur et forme :SolidMasse moléculaire :271.26Ref: TM-T1937
2mg34,00€5mg50,00€10mg63,00€25mg105,00€50mg187,00€100mg281,00€200mg420,00€1mL*10mM (DMSO)55,00€DBEQ
CAS :DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formule :C22H20N4Degré de pureté :98.93% - ≥95%Couleur et forme :SolidMasse moléculaire :340.42Ref: TM-T1969
2mg34,00€5mg52,00€10mg85,00€25mg152,00€50mg264,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)52,00€Abacavir sulfate
CAS :Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormule :C14H18N6OH2O4SDegré de pureté :99.79% - 99.85%Couleur et forme :White To Off-White SolidMasse moléculaire :335.38Shepherdin 79-87 acetate
Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.Formule :C43H68N12O14SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :1009.14Nelarabine
CAS :Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Formule :C11H15N5O5Degré de pureté :98.10% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Ref: TM-T6603
1mg40,00€2mg54,00€5mg84,00€10mg133,00€25mg234,00€50mg414,00€100mg520,00€500mg1.099,00€1mL*10mM (DMSO)84,00€Laquinimod
CAS :Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral
Formule :C19H17ClN2O3Degré de pureté :98.42% - 98.84%Couleur et forme :SolidMasse moléculaire :356.8ASP3026
CAS :ASP3026 has been used in trials studying the treatment of Solid Tumor, B-Cell Lymphoma, Advanced Malignancies,and Positive for Anaplastic Lymphoma Kinase.Formule :C29H40N8O3SDegré de pureté :98.78% - 99.81%Couleur et forme :SolidMasse moléculaire :580.74CCT 137690
CAS :CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).Formule :C26H31BrN8ODegré de pureté :98.51% - 99.89%Couleur et forme :SolidMasse moléculaire :551.48C-DIM12
CAS :C-DIM12 boosts Nurr1 gene expression, heightens Nurr1 protein in neurons, and improves survival against 6-OHDA.Formule :C23H17ClN2Degré de pureté :97.72% - ≥95%Couleur et forme :SolidMasse moléculaire :356.85AZD3759 hydrochloride
CAS :AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Formule :C22H24Cl2FN5O3Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :496.36Ref: TM-T4249
2mg34,00€5mg46,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€1mL*10mM (DMSO)49,00€Kahweol
CAS :Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFormule :C20H26O3Degré de pureté :99.26% - 99.86%Couleur et forme :Off-White To Yellow SolidMasse moléculaire :314.42
