Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(126 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(91 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Rhosin hydrochloride
CAS :Rhosin hydrochloride is a specific inhibitor of the RhoA subfamily Rho GTPases.Cost-effective and quality-assured.Formule :C20H20Cl2N6ODegré de pureté :97.33% - 98.92%Couleur et forme :SolidMasse moléculaire :431.318NADPH tetracyclohexanamine
CAS :NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.
Formule :C45H82N11O17P3Degré de pureté :98.73% - 99.05%Couleur et forme :SolidMasse moléculaire :1142.12Idasanutlin
CAS :Idasanutlin (Ro 5503781) (RG-7388) is an effective and specific p53-MDM2 inhibitor (IC50: 6 nM).Formule :C31H29Cl2F2N3O4Degré de pureté :99.13% - 99.88%Couleur et forme :SolidMasse moléculaire :616.48Ref: TM-T6254
2mg38,00€5mg57,00€10mg90,00€25mg150,00€50mg215,00€100mg356,00€500mg837,00€1mL*10mM (DMSO)79,00€CPTH2
CAS :CPTH2 is a histone acetyltransferase inhibitor modulating Gcn5 network.Formule :C14H14ClN3SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :291.8ZMC1
CAS :NSC-319726 (ZMC1), a mutant p53R175 reactivator, suppresses growth of fibroblasts that expresses the p53R175 mutation (IC50 = 8 nM).Formule :C11H14N4SDegré de pureté :98.97% - 99.76%Couleur et forme :SolidMasse moléculaire :234.32RAD51 Inhibitor B02
CAS :RAD51 Inhibitor B02 (B02) (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.Formule :C22H17N3ODegré de pureté :99.72% - 99.89%Couleur et forme :SolidMasse moléculaire :339.39Bendamustine
CAS :Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic LeukemiaFormule :C16H21Cl2N3O2Degré de pureté :99.99% - ≥98%Couleur et forme :SolidMasse moléculaire :358.26Ref: TM-T8380
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg245,00€50mg385,00€100mg575,00€500mg1.234,00€1mL*10mM (DMSO)89,00€Sertaconazole nitrate
CAS :Sertaconazole nitrate, a broad-spectrum topical antifungal, treats skin and mucosal infections.Formule :C20H15Cl3N2OS·HNO3Degré de pureté :98.66% - 99.65%Couleur et forme :SolidMasse moléculaire :500.78Almorexant
CAS :Almorexant (ACT 078573), a strong dual orexin receptor antagonist, has Ki of 1.3 nM for OX1 and 0.17 nM for OX2.Formule :C29H31F3N2O3Degré de pureté :97.75% - 98.02%Couleur et forme :SolidMasse moléculaire :512.56Grape Seed Extract
CAS :Grape Seed Extract (Grape Seed P.E.) is exudate from seeds of the grape plant Vitis vinifera, composed of oils and secondary plant metabolites.Formule :C32H30O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :590.581CVT-11127
CAS :CVT-11127 is an StearoylCoA Desaturase-1 (SCD1) inhibitor.Formule :C25H23Cl2N5O3Degré de pureté :98.32%Couleur et forme :SolidMasse moléculaire :512.39N-Ethylmaleimide
CAS :N-Ethylmaleimide (NEM) is a reagent for alkylation of free sulfhydryl groups, a cysteine protease inhibitor. Cost-effective and quality-assured.Formule :C6H7NO2Degré de pureté :99.50%Couleur et forme :White SolidMasse moléculaire :125.13Cucurbitacin IIA
CAS :1.Formule :C32H50O8Degré de pureté :98.62% - 99.87%Couleur et forme :SolidMasse moléculaire :562.73OSI-930
CAS :OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Formule :C22H16F3N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :443.44Tanespimycin
CAS :Tanespimycin (KOS 953) is an Hsp90 inhibitor (IC50=5 nM) and is selective. Tanespimycin depletes intracellular STK38/NDR1. High-Quality, Low-Cost!Formule :C31H43N3O8Degré de pureté :98.24% - 99.83%Couleur et forme :Dark Purple SolidMasse moléculaire :585.692-tert-Butyl-1,4-benzoquinone
CAS :TBQ, a BHA metabolite, activates Nrf2 and S-arylates Keap1 in RAW264.7 cells.Formule :C10H12O2Degré de pureté :97.19%Couleur et forme :SolidMasse moléculaire :164.2Quizartinib
CAS :Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.Formule :C29H32N6O4SDegré de pureté :98% - 99.42%Couleur et forme :SolidMasse moléculaire :560.67Ref: TM-T2066
5mg58,00€10mg79,00€25mg97,00€50mg127,00€100mg202,00€200mg300,00€500mg507,00€1mL*10mM (DMSO)71,00€Caudatin
CAS :Caudatin is one of the species of C-21 steroidal glycosides mainly isolated from the root of Cynanchum bungei Decne and exhibits potent anticancer activities.Formule :C28H42O7Degré de pureté :98.83% - 99.84%Couleur et forme :SolidMasse moléculaire :490.63Ref: TM-T3150
1mg52,00€5mg100,00€10mg166,00€25mg279,00€50mg398,00€100mg532,00€200mg705,00€1mL*10mM (DMSO)119,00€Taurochenodeoxycholic acid sodium
CAS :Sodium taurochenodeoxycholate: induces apoptosis, anti-inflammatory, boosts insulin, stimulates α2-cells, increases [Ca(2+)](c).Formule :C26H44NNaO6SDegré de pureté :98.23% - 99.56%Couleur et forme :White To Off-White PowderMasse moléculaire :521.68GSK-J4
CAS :GSK-J4 (GSK J4 HCl) is a cell permeable prodrug of GSK-J1, a dual inhibitor of the H3K27me3/me2 demethylases JMJD3/KDM6B and UTX/KDM6A. Cost effective and quality assured.Formule :C24H27N5O2Degré de pureté :98.24% - 99.98%Couleur et forme :SolidMasse moléculaire :417.5Ref: TM-T3100
2mg52,00€5mg86,00€10mg122,00€25mg215,00€50mg345,00€100mg523,00€200mg663,00€1mL*10mM (DMSO)134,00€Angelicin
CAS :Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.Formule :C11H6O3Degré de pureté :99.86% - 99.89%Couleur et forme :White SolidMasse moléculaire :186.16Fimasartan
CAS :Fimasartan (BR-A-657), an ARB, treats hypertension and heart failure; safe with hydrochlorothiazide.Formule :C27H31N7OSDegré de pureté :98.96%Couleur et forme :SolidMasse moléculaire :501.65Lenalidomide hemihydrate
CAS :Lenalidomide hemihydrate inhibits TNF-α (IC50=13nM) and binds CRBN/DDB1 complexes.Formule :C13H13N3O3H2ODegré de pureté :96.22%Couleur et forme :SolidMasse moléculaire :268.28ASTX660
CAS :Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Formule :C30H42FN5O3Degré de pureté :98.33% - 99.85%Couleur et forme :SolidMasse moléculaire :539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€1mL*10mM (DMSO)163,00€Palomid 529
CAS :Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Formule :C24H22O6Degré de pureté :98.40% - 98.59%Couleur et forme :SolidMasse moléculaire :406.43BI-6C9
CAS :BI-6C9 is an inhibitor of tBid (Kd = 20 μM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.Formule :C23H25N3O4S2Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :471.59Ref: TM-T5827
1mg66,00€2mg95,00€5mg144,00€10mg210,00€25mg376,00€50mg557,00€100mg782,00€200mg1.035,00€1mL*10mM (DMSO)150,00€Alogliptin
CAS :Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9Formule :C18H21N5O2Degré de pureté :99.63%Couleur et forme :SolidMasse moléculaire :339.39Ref: TM-T6192
2mg34,00€5mg49,00€10mg60,00€25mg81,00€50mg92,00€100mg129,00€200mg178,00€1mL*10mM (DMSO)50,00€Takinib
CAS :Takinib (EDHS-206) is a specific and effective TAK1 inhibitor(IC50= 9.5 nM).Formule :C18H18N4O2Degré de pureté :98.29% - 99.35%Couleur et forme :SolidMasse moléculaire :322.36ML-210
CAS :ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Formule :C22H20Cl2N4O4Degré de pureté :97% - 99.03%Couleur et forme :SolidMasse moléculaire :475.32Ref: TM-T8375
1mg34,00€2mg49,00€5mg82,00€10mg133,00€25mg234,00€50mg393,00€100mg528,00€1mL*10mM (DMSO)86,00€UMI-77
CAS :UMI-77 is a selective Mcl-1 inhibitor. UMI-77 binds to the BH3-binding groove of Mcl-1.Cost-effective and quality-assured.Formule :C18H14BrNO5S2Degré de pureté :96% - 99.57%Couleur et forme :SolidMasse moléculaire :468.34Ref: TM-T6034
1mg40,00€2mg52,00€5mg84,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€200mg692,00€500mg1.035,00€1mL*10mM (DMSO)86,00€ACBI1
CAS :ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50sFormule :C49H58FN9O7SDegré de pureté :97.54% - 98.15%Couleur et forme :SolidMasse moléculaire :936.1[8]-Shogaol
CAS :[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.Formule :C19H28O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :304.42Ref: TM-T5430
1mg90,00€5mg197,00€10mg339,00€25mg560,00€50mg793,00€100mg1.063,00€1mL*10mM (DMSO)219,00€R-7050
CAS :R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Formule :C16H8ClF3N4SDegré de pureté :98.64% - 99.8%Couleur et forme :SolidMasse moléculaire :380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€1mL*10mM (DMSO)71,00€(+)-Nortrachelogenin
CAS :(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Formule :C20H22O7Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :374.38Cidofovir dihydrate
CAS :Cidofovir dihydrate: Injectable anti-CMV; suppresses CMV by inhibiting viral DNA polymerase; treats CMV retinitis in AIDS.Formule :C8H18N3O8PDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :315.22Erdafitinib
CAS :Erdafitinib (JNJ-42756493) is a quinoxaline derivative compound, acts on FGFR1/2/3/4.Formule :C25H30N6O2Degré de pureté :97.00% - 99.36%Couleur et forme :SolidMasse moléculaire :446.54ASK1-IN-1
CAS :ASK1-IN-1 inhibits apoptosis kinase 1, crucial in cell stress responses, with 21 nM IC50.Formule :C19H19N9O2Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :405.41Ref: TM-T9697
1mg90,00€5mg215,00€10mg321,00€25mg582,00€50mg873,00€100mg1.216,00€1mL*10mM (DMSO)236,00€Taurochenodeoxycholic Acid
CAS :Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.Formule :C26H45NO6SDegré de pureté :99.53% - 99.86%Couleur et forme :SolidMasse moléculaire :499.7MGH-CP1
CAS :MGH-CP1 inhibits TEAD2/4 auto-palmitoylation with IC50 of 710 and 672 nM, respectively.Formule :C20H24N4OSDegré de pureté :98.66%Couleur et forme :SolidMasse moléculaire :368.5Ref: TM-T9032
2mg38,00€5mg57,00€10mg93,00€25mg177,00€50mg313,00€100mg507,00€200mg710,00€1mL*10mM (DMSO)67,00€BAY 61-3606 dihydrochloride
CAS :BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).Formule :C20H18N6O3·2HClDegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :463.32Ref: TM-T6776
1mg35,00€5mg79,00€10mg110,00€25mg177,00€50mg264,00€100mg385,00€200mg535,00€1mL*10mM (DMSO)93,00€Lycorine
CAS :Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.Formule :C16H17NO4Degré de pureté :98.60% - 99.95%Couleur et forme :SolidMasse moléculaire :287.312BAct
CAS :2BAct is a novel eif2b activator, preventing neurological defects caused by a chronic integrated stress responseFormule :C19H16ClF3N4O3Degré de pureté :97.97% - 99.04%Couleur et forme :SolidMasse moléculaire :440.8Irigenin
CAS :Irigenin mediates its antimetastatic effect by specifically and selectively blocking the α9β1 and α4β1 integrin binding sites on the C-C loop of the ExtraFormule :C18H16O8Degré de pureté :99.50% - 99.85%Couleur et forme :SolidMasse moléculaire :360.31ML141
CAS :ML141 (CID-2950007) is an effective, specific and reversible non-competitive inhibitor of Rho family GTPase cdc42 (IC50: 200 nM).Formule :C22H21N3O3SDegré de pureté :99.36% - 99.56%Couleur et forme :SolidMasse moléculaire :407.49Ref: TM-T2463
1mg37,00€2mg52,00€5mg69,00€10mg101,00€25mg200,00€50mg321,00€100mg515,00€1mL*10mM (DMSO)71,00€SW106065
CAS :SW106065 is a novel pharmacologic inducer of apoptosis in MPNST (malignant peripheral nerve sheath tumors). SW106065 inhibits ATP consumption of sMPNST.Formule :C10H8N2OSDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :204.25(S)-(+)-Rolipram
CAS :(S)-(+)-Rolipram ((+)-Rolipram) inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 μM, has anti-inflammatory and anti-depressant activity in theFormule :C16H21NO3Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :275.34Nur77 modulator 1
CAS :Nur77 modulator 1: binds at 3.58 μM, boosts expression, alters location, triggers ER stress/autophagy, induces apoptosis, and fights hepatoma.Formule :C28H25N5O2SDegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :495.6Ref: TM-T40130
1mg64,00€5mg140,00€10mg226,00€25mg373,00€50mg509,00€100mg702,00€200mg944,00€1mL*10mM (DMSO)153,00€KRIBB11
CAS :KRIBB11 is an inhibitor of Heat shock factor (HSF) inhibitor.Formule :C13H12N6O2Degré de pureté :97.25% - 99.91%Couleur et forme :SolidMasse moléculaire :284.27Ref: TM-T3652
5mg49,00€10mg73,00€25mg150,00€50mg249,00€100mg484,00€200mg680,00€500mg1.035,00€1mL*10mM (DMSO)50,00€Asperosaponin VI
CAS :Asperosaponin VI, from Dipsacus asper rhizome, treats back pain, hematoma, and fractures.Formule :C47H76O18Degré de pureté :97.15% - 99.79%Couleur et forme :SolidMasse moléculaire :929.10Ginsenoside Rg6
CAS :Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cellsFormule :C42H70O12Degré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :767
![[8]-Shogaol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT5430.webp&w=3840&q=75)
