Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(126 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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Berbamine dihydrochloride
CAS :Berbamine dihydrochloride (Berbamine), a natural compound derived from the Berberis amurensis plant, has been shown to exhibit antitumor activity in several Ys.Formule :C37H42Cl2N2O6Degré de pureté :95% - 99.99%Couleur et forme :SolidMasse moléculaire :681.65Scoulerine
CAS :Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1).Formule :C19H21NO4Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :327.37SP-141
CAS :SP 141 is a MDM2 inhibitor.SP-141 promotes MDM2 auto-ubiquitination and degradation, with anticancer activity.Formule :C22H16N2ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :324.38BIO-acetoxime
CAS :BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.Formule :C18H12BrN3O3Degré de pureté :97.15%Couleur et forme :SolidMasse moléculaire :398.21Ref: TM-T6787
1mg34,00€2mg46,00€5mg66,00€10mg99,00€25mg177,00€50mg281,00€100mg439,00€1mL*10mM (DMSO)73,00€5,7,4'-Trimethoxyflavone
CAS :5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.Formule :C18H16O5Degré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :312.32(Rac)-Antineoplaston A10
CAS :Antineoplaston A10 is the first identified human antineoplaston, naturally occurring with anti-proliferative properties.Formule :C13H14N2O3Degré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :246.26Ref: TM-T5379
1mg38,00€5mg84,00€10mg122,00€25mg198,00€50mg295,00€100mg424,00€200mg593,00€1mL*10mM (DMSO)90,00€Dehydroeffusol
CAS :Dehydroeffusol: anti-cancer, anxiolytic, sedative; halts gastric cancer growth via ER stress and apoptosis.Formule :C17H14O2Degré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :250.29Domatinostat tosylate
CAS :4SC-202 is a class I HDAC inhibitor targeting HDAC1/2/3; shows activity against LSD1. IC50: HDAC1 (1.20 μM), HDAC2 (1.12 μM), HDAC3 (0.57 μM).Formule :C30H29N5O6S2Degré de pureté :97.35% - >99.99%Couleur et forme :Solid PowderMasse moléculaire :619.71Spautin-1
CAS :Spautin-1 is an autophagy inhibitor that can suppress the deubiquitination activity of ubiquitin-specific peptidase USP10 and USP13. Cost-effective and quality-assured.Formule :C15H11F2N3Degré de pureté :97.69% - 98.99%Couleur et forme :SolidMasse moléculaire :271.26Ref: TM-T1937
2mg34,00€5mg50,00€10mg63,00€25mg105,00€50mg187,00€100mg281,00€200mg420,00€1mL*10mM (DMSO)55,00€AKT inhibitor VIII
CAS :AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3.Formule :C34H29N7ODegré de pureté :98.31% - 98.65%Couleur et forme :Pale Yellow SolidMasse moléculaire :551.64LJH685
CAS :LJH685 is an effective pan-RSK inhibitor for RSK1/2/3 (IC50: 6/5/4 nM).Formule :C22H21F2N3ODegré de pureté :99.13% - 99.78%Couleur et forme :SolidMasse moléculaire :381.42Ref: TM-T6877
1mg37,00€5mg88,00€10mg127,00€25mg240,00€50mg401,00€100mg603,00€200mg848,00€1mL*10mM (DMSO)87,00€PF-543 hydrochloride
CAS :PF-543 hydrochloride (PF-543) inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2Formule :C27H32ClNO4SDegré de pureté :98.9% - 99.93%Couleur et forme :SolidMasse moléculaire :502.1Sesamol
CAS :Sesamol (1,3-Benzodioxol-5-ol) could decrease lung inflammation and lipopolysaccharide (LPS)-induced lung injury in rats.
Formule :C7H6O3Degré de pureté :99.67% - 99.76%Couleur et forme :White To Off-White Crystalline PowderMasse moléculaire :138.12Ginsenoside F5
CAS :Ginsenoside F5 is a natural product from Panax ginseng C. A. Mey, remarkably inhibits the growth of HL-60 cells by the apoptosis pathway
Formule :C41H70O13Degré de pureté :99.78% - 99.86%Couleur et forme :SolidMasse moléculaire :770.99Mdivi-1
CAS :Mdivi-1 (Mitochondrial division inhibitor 1) is a mitochondrial division inhibitor that inhibits DRP1 and Dynamin I (IC50=1-10 μM).Formule :C15H10Cl2N2O2SDegré de pureté :96.57% - 99.23%Couleur et forme :SolidMasse moléculaire :353.22Ref: TM-T1907
5mg44,00€10mg52,00€25mg95,00€50mg144,00€100mg215,00€200mg319,00€500mg530,00€1mL*10mM (DMSO)48,00€Paris saponin VII
CAS :Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.Formule :C51H82O21Degré de pureté :99.51% - 99.63%Couleur et forme :SolidMasse moléculaire :1031.18Sophoridine
CAS :Sophoridine, a natural Chinese anticancer drug, has a potent derivative 6b targeting DNA topoisomerase I in tumor cells, inducing apoptosis.Formule :C15H24N2ODegré de pureté :97.33% - 99.28%Couleur et forme :SolidMasse moléculaire :248.36DBEQ
CAS :DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.Formule :C22H20N4Degré de pureté :98.93% - ≥95%Couleur et forme :SolidMasse moléculaire :340.42Ref: TM-T1969
2mg34,00€5mg52,00€10mg85,00€25mg152,00€50mg264,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)52,00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Formule :C60H82N8O10Degré de pureté :97.76%Couleur et forme :SolidMasse moléculaire :1075.36Dipyrithione
CAS :Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activityFormule :C10H8N2O2S2Degré de pureté :99.9%Couleur et forme :Beige Crystalline PowderMasse moléculaire :252.31Phenoxodiol
CAS :Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP)Formule :C15H12O3Degré de pureté :98.07% - 99.18%Couleur et forme :SolidMasse moléculaire :240.25Ref: TM-T16522
1mg63,00€5mg137,00€10mg215,00€25mg353,00€50mg537,00€100mg767,00€1mL*10mM (DMSO)150,00€Anisomycin
CAS :Anisomycin (NSC-76712), an antibiotic from Streptomyces, blocks protein/DNA synthesis by targeting peptidyl transferase/80S ribosomes.Formule :C14H19NO4Degré de pureté :98.33% - 99.81%Couleur et forme :White Crystalline SolidMasse moléculaire :265.3ARS-853
CAS :ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cellsFormule :C22H29ClN4O3Degré de pureté :97.43% - 98.4%Couleur et forme :SolidMasse moléculaire :432.94Ref: TM-T7414
1mg142,00€5mg353,00€10mg525,00€25mg843,00€50mg1.144,00€100mg1.549,00€500mg3.087,00€1mL*10mM (DMSO)338,00€Lorlatinib
CAS :Lorlatinib (PF-6463922) is an orally available, ATP-competitive inhibitor of the receptor tyrosine kinases, anaplastic lymphoma kinase (ALK) and C-ros oncogeneFormule :C21H19FN6O2Degré de pureté :99.77% - 99.95%Couleur et forme :SolidMasse moléculaire :406.41Ref: TM-T3061
1mg34,00€2mg42,00€5mg60,00€10mg89,00€25mg137,00€50mg212,00€100mg374,00€1mL*10mM (DMSO)66,00€GSK963
CAS :GSK963 (Racemate), a structurally distinct, potent and selective inhibitor of RIP1 kinase(IC50=29 nM).Formule :C14H18N2ODegré de pureté :98.00%Couleur et forme :SolidMasse moléculaire :230.31Ref: TM-T5054
1mg34,00€2mg48,00€5mg74,00€10mg113,00€25mg222,00€50mg358,00€100mg523,00€1mL*10mM (DMSO)82,00€Carvacrol
CAS :1.Formule :C10H14ODegré de pureté :99.05%Couleur et forme :Needles LiquidMasse moléculaire :150.22MFCD01917484
CAS :MFCD01917484: A thiophene derivative with ligand, catalyst, and photosensitizer roles, used in biochemical research and drug development.Formule :C14H15NO3SDegré de pureté :98.09%Couleur et forme :SolidMasse moléculaire :277.34Taccalonolide A
CAS :Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it isFormule :C36H46O14Degré de pureté :98.16% - 99.4%Couleur et forme :SolidMasse moléculaire :702.74Onatasertib
CAS :Onatasertib (CC223) is an orally available mTOR inhibitor with potential antitumor activity.Formule :C21H27N5O3Degré de pureté :99.14% - 99.93%Couleur et forme :SolidMasse moléculaire :397.47β-Elemonic Acid
CAS :β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects, which inhibits proliferation by inducing hypoploid cells and cell apoptosis.Formule :C30H46O3Degré de pureté :99.61% - 99.8%Couleur et forme :SolidMasse moléculaire :454.68Ref: TM-T2S0618
1mg35,00€5mg75,00€10mg110,00€25mg192,00€50mg286,00€100mg425,00€200mg612,00€1mL*10mM (DMSO)84,00€BAY 11-7082
CAS :BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).Formule :C10H9NO2SDegré de pureté :98% - 99.92%Couleur et forme :SolidMasse moléculaire :207.25Ref: TM-T1902
5mg48,00€10mg54,00€25mg90,00€50mg161,00€100mg251,00€200mg378,00€500mg627,00€1mL*10mM (DMSO)50,00€(6R)-FR054
CAS :(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.Formule :C14H19NO8Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :329.3(-)-Epipodophyllotoxin
CAS :(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.Formule :C22H22O8Degré de pureté :99.72% - 99.97%Couleur et forme :SolidMasse moléculaire :414.41PD173074
CAS :PD173074 inhibits FGFR1 (IC50: 25 nM) and VEGFR2 (100-200 nM); ~1000x more selective for FGFR1 over PDGFR/c-Src.Formule :C28H41N7O3Degré de pureté :98.15% - 98.21%Couleur et forme :Yellow SolidMasse moléculaire :523.67Ref: TM-T2642
5mg40,00€10mg54,00€25mg94,00€50mg133,00€100mg210,00€200mg371,00€500mg620,00€1mL*10mM (DMSO)56,00€JNJ-7706621
CAS :JNJ-7706621 is a potent aurora kinase inhibitor, and also inhibits CDK1 and CDK2.Formule :C15H12F2N6O3SDegré de pureté :99.1% - 99.85%Couleur et forme :SolidMasse moléculaire :394.36Ref: TM-T6126
1mg48,00€5mg100,00€10mg155,00€25mg268,00€50mg432,00€100mg595,00€200mg833,00€1mL*10mM (DMSO)94,00€WP1066
CAS :WP1066 is a inhibitor of JAK2 (IC50: 2.30 μM) and STAT3 (IC50: 2.43 μM) in HEL cells; shows activity to JAK2, STAT3/5, and ERK1/2, not JAK1 and JAK3.Formule :C17H14BrN3ODegré de pureté :98.92% - 99.73%Couleur et forme :SolidMasse moléculaire :356.22Gemcitabine hydrochloride
CAS :Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formule :C9H11F2N3O4·HClDegré de pureté :99.28% - 99.98%Couleur et forme :White Crystalline Granular OdorlessMasse moléculaire :299.66AZ960
CAS :AZ960 is an effective ATP competitive JAK2 inhibitor (IC50/Ki: <3 nM and0.45 nM).Formule :C18H16F2N6Degré de pureté :96.02% - 99.88%Couleur et forme :SolidMasse moléculaire :354.36Quinidine
CAS :Quinidine is a stereoisomer of the antimalarial agent quinine and a class Ia antiarrhythmic agent. for the treatment of abnormal heart rhythms and also malaria.Formule :C20H24N2O2Degré de pureté :97.03% - 99.99%Couleur et forme :Crystals With 2 5 Mol Water Of Crystallization; Crystals From Dilute Alcohol Physical Description Crystals Or White Powder (Ntp 1992)Masse moléculaire :324.42AEE788
CAS :AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.Formule :C27H32N6Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :440.58Ref: TM-T2116
2mg47,00€5mg70,00€10mg103,00€25mg188,00€50mg325,00€100mg490,00€500mg1.103,00€1mL*10mM (DMSO)77,00€18α-Glycyrrhetinic acid
CAS :18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.Formule :C30H46O4Degré de pureté :98.54% - 99.68%Couleur et forme :SolidMasse moléculaire :470.68Antineoplaston A10
CAS :Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formule :C13H14N2O3Degré de pureté :99.42%Couleur et forme :SolidMasse moléculaire :246.26Ref: TM-T7131
2mg44,00€5mg67,00€10mg103,00€25mg193,00€50mg295,00€100mg425,00€200mg595,00€1mL*10mM (DMSO)73,00€Valepotriate
CAS :Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.Formule :C22H30O8Degré de pureté :97.29% - 99.90%Couleur et forme :SolidMasse moléculaire :422.47(E)-Flavokawain A
CAS :(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway.Formule :C18H18O5Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :314.33Atractylenolide III
CAS :Atractylenolide III could treat cognitive issues and lung cancer by modulating apoptosis factors.
Formule :C15H20O3Degré de pureté :99.53% - 99.82%Couleur et forme :SolidMasse moléculaire :248.32Oleuropein
CAS :Oleuropein is an antioxidant polyphenol isolated from olive leaf.Formule :C25H32O13Degré de pureté :98% - 99.95%Couleur et forme :Brown PowderMasse moléculaire :540.51Columbianadin
CAS :Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim.Formule :C19H20O5Degré de pureté :98.44% - 99.48%Couleur et forme :SolidMasse moléculaire :328.36Flavokawain C
CAS :Flavokawain C: natural chalcone from Kava with potential as a colon cancer drug.Formule :C17H16O5Degré de pureté :99.94% - ≥95%Couleur et forme :SolidMasse moléculaire :300.31Hirsutine
CAS :Hirsutine induces apoptosis and is a potent Dengue virus inhibitor exhibiting low cytotoxicity.Hirsutine has anticancer, cardioprotective, anti-hypertensive andFormule :C22H28N2O3Degré de pureté :99.36% - 99.98%Couleur et forme :SolidMasse moléculaire :368.47GSK2606414
CAS :GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.Formule :C24H20F3N5ODegré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :451.44
