Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5593 produits trouvés pour "Apoptose"
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BMS-1
CAS :<p>BMS-1 is a PD-1/PD-L1 inhibitor and immunomodulator; it targets the CD274 gene product, PD-L1, linked to tumor evasion and higher mortality.</p>Formule :C29H33NO5Degré de pureté :99.40% - 99.81%Couleur et forme :SolidMasse moléculaire :475.582-methoxycinnamaldehyde
CAS :<p>2-methoxycinnamaldehyde is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.</p>Formule :C10H10O2Degré de pureté :98%Couleur et forme :Physical Description Yellow Crystals (Ntp 1992)Masse moléculaire :162.19Desoxyrhaponticin
CAS :<p>Deoxyrhaponticin may reduce post-meal blood sugar and inhibit cancer cell growth.</p>Formule :C21H24O8Degré de pureté :99.97% - ≥95%Couleur et forme :SolidMasse moléculaire :404.41SU9516
CAS :<p>SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.</p>Formule :C13H11N3O2Degré de pureté :99.34% - 99.87%Couleur et forme :SolidMasse moléculaire :241.25Erastin
CAS :<p>Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!</p>Formule :C30H31ClN4O4Degré de pureté :98% - 99.75%Couleur et forme :SolidMasse moléculaire :547.04PKCβ inhibitor 1
CAS :<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Formule :C24H21N5O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :411.46L-Ascorbic acid sodium salt
CAS :<p>L-Ascorbic acid sodium salt (Vitamin C sodium salt) is a more bioavailable form of vitamin C that is an alternative to taking ascorbic acid as a supplement.</p>Formule :C6H7NaO6Degré de pureté :98.73% - 99.75%Couleur et forme :Less Solid PowderMasse moléculaire :198.11Zinc Protoporphyrin
CAS :<p>Zinc Protoporphyrin is an oral HO-1 inhibitor that reduces PG's protection against H2O2 and has anti-cancer properties.</p>Formule :C34H32N4O4ZnDegré de pureté :95.43% - 99.27%Couleur et forme :SolidMasse moléculaire :626.02A-1155463
CAS :<p>A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2, BCL-W and MCL-1.</p>Formule :C35H32FN5O4S2Degré de pureté :96.1% - 99%Couleur et forme :SolidMasse moléculaire :669.79LY-294002 hydrochloride
CAS :<p>LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.</p>Formule :C19H17NO3·HClDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :343.81Capmatinib xHCl
CAS :<p>Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50</p>Formule :C23H18ClFN6ODegré de pureté :98.62% - 99.81%Couleur et forme :SolidMasse moléculaire :448.89PI-1840
CAS :<p>PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.</p>Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.47Cynaroside
CAS :<p>Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.</p>Formule :C21H20O11Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :448.382'-OMe-Guanosine
CAS :<p>2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.</p>Formule :C11H15N5O5Degré de pureté :99.93%Couleur et forme :White SolidMasse moléculaire :297.27Linderalactone
CAS :<p>1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.</p>Formule :C15H16O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :244.29Larotrectinib sulfate
CAS :<p>Larotrectinib sulfate (LOXO-101 sulfate) is an oral active and specific ATP-competitive inhibitor of tropomyosin receptor kinases (TRK).</p>Formule :C21H22F2N6O2·H2O4SDegré de pureté :98.62% - 99.76%Couleur et forme :SolidMasse moléculaire :526.51TVB-3166
CAS :<p>TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).</p>Formule :C24H24N4ODegré de pureté :99.53% - 99.57%Couleur et forme :SolidMasse moléculaire :384.47Sirtinol
CAS :<p>Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).</p>Formule :C26H22N2O2Degré de pureté :97.12% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Embelin
CAS :<p>Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).</p>Formule :C17H26O4Degré de pureté :97.07% - 99.88%Couleur et forme :SolidMasse moléculaire :294.39CPI1189
CAS :<p>CPI1189 (REN-1189) is a TNF-a release inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.</p>Formule :C13H18N2O2Degré de pureté :98.34% - 99.51%Couleur et forme :SolidMasse moléculaire :234.29Betulin
CAS :<p>Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene.</p>Formule :C30H50O2Degré de pureté :98.52% - 99.88%Couleur et forme :White Crystalline PowderMasse moléculaire :442.72GSK 3 Inhibitor IX
CAS :<p>GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.</p>Formule :C16H10BrN3O2Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :356.17FR 180204
CAS :<p>FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.</p>Formule :C18H13N7Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :327.34MSC 2032964A
CAS :<p>MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.</p>Formule :C16H13F3N6ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :362.31CHS-828
CAS :<p>CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).</p>Formule :C19H22ClN5ODegré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :371.86LW6
CAS :<p>LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.</p>Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Wogonin
CAS :<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Formule :C16H12O5Degré de pureté :98% - 99.8%Couleur et forme :Yellow CrystalMasse moléculaire :284.26Formosanin C
CAS :<p>Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.</p>Formule :C51H82O20Degré de pureté :99.75% - >99.99%Couleur et forme :SolidMasse moléculaire :1015.18Cyasterone
CAS :<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Formule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65Quisinostat
CAS :<p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>Formule :C21H26N6O2Degré de pureté :96.01% - ≥98%Couleur et forme :SolidMasse moléculaire :394.47α-Hederin
CAS :<p>Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.</p>Formule :C41H66O12Degré de pureté :99.44% - 99.89%Couleur et forme :SolidMasse moléculaire :750.96BMS-536924
CAS :<p>BMS-536924 (BMS 536924) is an ATP-competitive IGF-1R/IR inhibitor with IC50 of 100 nM/73 nM, modest activity for Mek, Fak, and Lck with very little activity for</p>Formule :C25H26ClN5O3Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :479.96Chelidonine
CAS :<p>Chelidonine from Chelidonium majus triggers HeLa cell apoptosis, may reverse MDR, boost chemotherapeutics against leukemia, and inhibit cancer cell metastasis.</p>Formule :C20H19NO5Degré de pureté :98% - 99.61%Couleur et forme :SolidMasse moléculaire :353.37Tasisulam
CAS :<p>Tasisulam (LY573636) is an apoptosis inducer and an antitumor agent via the intrinsic pathway.</p>Formule :C11H6BrCl2NO3S2Degré de pureté :99% - >99.99%Couleur et forme :SolidMasse moléculaire :415.11Epibrassinolide
CAS :<p>Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator with</p>Formule :C28H48O6Degré de pureté :97.57% - 98.11%Couleur et forme :SolidMasse moléculaire :480.68Levomenol
CAS :<p>Levomenol, or (-)-α-Bisabolol, is a sesquiterpene in aromatic plant oils with antioxidant, anti-inflammatory, and anti-apoptotic properties.</p>Formule :C15H26ODegré de pureté :96.01%Couleur et forme :Clear To Yellowish LiquidMasse moléculaire :222.37Sal003
CAS :<p>Sal003, an effective cell-permeable analog, inhibitis the eIF2α phosphatase.</p>Formule :C18H15Cl4N3OSDegré de pureté :99.17% - 99.77%Couleur et forme :SolidMasse moléculaire :463.21Hypericin
CAS :<p>Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.</p>Formule :C30H16O8Degré de pureté :99.05% - ≥98%Couleur et forme :Red-Coloured Anthraquinone-DerivativeMasse moléculaire :504.44Afatinib
CAS :<p>Afatinib (BIBW 2992) is an irreversible and orally EGFR family inhibitor that inhibits EGFR and HER2. Afatinib has antitumor activity. Cost effective and quality assured.</p>Formule :C24H25ClFN5O3Degré de pureté :98.56% - 99.9%Couleur et forme :Off-White SolidMasse moléculaire :485.94Infigratinib
CAS :<p>Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and</p>Formule :C26H31Cl2N7O3Degré de pureté :98% - 98.97%Couleur et forme :SolidMasse moléculaire :560.48Glycochenodeoxycholic Acid
CAS :<p>Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid.</p>Formule :C26H43NO5Degré de pureté :97% - 99.97%Couleur et forme :SolidMasse moléculaire :449.62Telekin
CAS :<p>Telekin, a sesquiterpene lactone from Carpesium divaricatum, strongly inhibits cancer cell growth.</p>Formule :C15H20O3Degré de pureté :99.86% - 99.97%Couleur et forme :SolidMasse moléculaire :248.32AT7519
CAS :<p>AT7519 is a CDK1/2/4/6/9 inhibitor (IC50: 10-210 nM). It is less effective to CDK3 and little active to CDK7.</p>Formule :C16H17Cl2N5O2Degré de pureté :98.88% - 99.65%Couleur et forme :SolidMasse moléculaire :382.24Malabaricone B
CAS :<p>Malabaricone B is a Spice-derived phenolic, it induces mitochondrial damage in lung cancer cells via a p53-independent pathway.</p>Formule :C21H26O4Degré de pureté :99.84% - 99.91%Couleur et forme :SolidMasse moléculaire :342.43(E/Z)-TG003
CAS :<p>(E/Z)-TG003 is a potent and ATP-competitive Cdc2-like kinase (Clk) inhibitor.</p>Formule :C13H15NO2SDegré de pureté :98% - 99.04%Couleur et forme :SolidMasse moléculaire :249.33ENMD-2076
CAS :<p>ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.</p>Formule :C21H25N7Degré de pureté :97.63% - ≥95%Couleur et forme :SolidMasse moléculaire :375.47m-3M3FBS
CAS :<p>m-3M3FBS is a phospholipase C (PLC) activator.</p>Formule :C16H16F3NO2SDegré de pureté :99.66%Couleur et forme :SolidMasse moléculaire :343.36Polygalacin D
CAS :<p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>Formule :C57H92O27Degré de pureté :98.95% - ≥98%Couleur et forme :SolidMasse moléculaire :1209.4Salubrinal
CAS :<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Formule :C21H17Cl3N4OSDegré de pureté :97.25% - >99.99%Couleur et forme :SolidMasse moléculaire :479.81Choline
CAS :<p>Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins</p>Formule :C5H15NO2Degré de pureté :99.97% - ≥98%Couleur et forme :LiquidMasse moléculaire :121.18
