Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(127 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(90 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6170 produits trouvés pour "Apoptose"
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MG-132
CAS :MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!Formule :C26H41N3O5Degré de pureté :95% - 99.99%Couleur et forme :White To Off-White PowderMasse moléculaire :475.62Ref: TM-T2154
10mg46,00€25mg84,00€50mg137,00€100mg205,00€200mg356,00€500mg447,00€1mL*10mM (DMSO)44,00€Taurodeoxycholic acid sodium hydrate
CAS :Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.Formule :C26H46NNaO7SDegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :539.70Triglycidyl isocyanurate
CAS :Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.Formule :C12H15N3O6Degré de pureté :99.01%Couleur et forme :White Solid ParticulatesMasse moléculaire :297.26GSK4112
CAS :GSK4112 (SR6452) is a Rev-erbα agonist with EC50 of 0.4 μM, also is a small molecule chemical probe for the cell biology of the nuclear heme receptor Rev-erbα.Formule :C18H21ClN2O4SDegré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :396.89CCF642
CAS :CCF642 (AC1LYELL) is a novel PDI-inhibiting compound with antimyeloma activity.Formule :C15H10N2O4S3Degré de pureté :97.12% - 98.82%Couleur et forme :SolidMasse moléculaire :378.45Ref: TM-T6800
1mg34,00€2mg46,00€5mg63,00€10mg93,00€25mg170,00€50mg281,00€100mg432,00€200mg618,00€1mL*10mM (DMSO)66,00€PFI-90
CAS :PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.Formule :C11H10N4ODegré de pureté :99.46%Couleur et forme :SolidMasse moléculaire :214.22Triptonide
CAS :Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.Formule :C20H22O6Degré de pureté :99.11% - 99.64%Couleur et forme :White Crystalline PowderMasse moléculaire :358.39Ref: TM-T5S1058
1mg52,00€2mg74,00€5mg108,00€10mg158,00€25mg268,00€50mg409,00€100mg595,00€200mg833,00€1mL*10mM (DMSO)133,00€Nelarabine
CAS :Nelarabine (GW 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells.Formule :C11H15N5O5Degré de pureté :98.10% - 99.6%Couleur et forme :White SolidMasse moléculaire :297.27Ref: TM-T6603
1mg40,00€2mg54,00€5mg84,00€10mg133,00€25mg234,00€50mg414,00€100mg520,00€500mg1.099,00€1mL*10mM (DMSO)84,00€Abacavir sulfate
CAS :Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormule :C14H18N6OH2O4SDegré de pureté :99.79% - 99.85%Couleur et forme :White To Off-White SolidMasse moléculaire :335.38Prucalopride Succinate
CAS :Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Formule :C18H26ClN3O3·C4H6O4Degré de pureté :99.24%Couleur et forme :SolidMasse moléculaire :485.96Bromosporine
CAS :Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively.Formule :C17H20N6O4SDegré de pureté :99.65% - 99.79%Couleur et forme :SolidMasse moléculaire :404.44Ref: TM-T6255
1mg44,00€2mg57,00€5mg93,00€10mg133,00€25mg260,00€50mg416,00€100mg665,00€200mg888,00€1mL*10mM (DMSO)92,00€Hispidol
CAS :Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFormule :C15H10O4Degré de pureté :97.86% - 98.45%Couleur et forme :SolidMasse moléculaire :254.24Ref: TM-T4319
1mg42,00€2mg56,00€5mg93,00€10mg137,00€25mg200,00€50mg260,00€100mg409,00€200mg560,00€500mg954,00€1mL*10mM (DMSO)92,00€4-Methyldaphnetin
CAS :4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.Formule :C10H8O4Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :192.17Brevilin A
CAS :Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formule :C20H26O5Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :346.42Ref: TM-T4672
1mg90,00€5mg203,00€10mg350,00€25mg578,00€50mg797,00€100mg1.071,00€500mg2.187,00€1mL*10mM (DMSO)224,00€Methotrexate disodium
CAS :Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitorFormule :C20H20N8Na2O5Degré de pureté :99.77% - 99.96%Couleur et forme :SolidMasse moléculaire :498.4Actein
CAS :Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.Formule :C37H56O11Degré de pureté :≥98%Couleur et forme :Brown PowderMasse moléculaire :676.83UCF 101
CAS :UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.Formule :C27H17N3O5SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :495.51Ref: TM-T21919
1mg38,00€2mg50,00€5mg84,00€10mg130,00€25mg259,00€50mg409,00€100mg590,00€1mL*10mM (DMSO)93,00€Gomisin N
CAS :Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.Formule :C23H28O6Degré de pureté :99.97% - >99.99%Couleur et forme :SolidMasse moléculaire :400.46PHYTOSPHINGOSINE
CAS :Phytosphingosine: anticancer phospholipid; triggers apoptosis in cancer cells via caspase 8 activation and Bax translocation.Formule :C18H39NO3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :317.51AZD-7648
CAS :AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity.Formule :C18H20N8O2Degré de pureté :99.03% - 99.85%Couleur et forme :SolidMasse moléculaire :380.4Ref: TM-T7122
1mg38,00€5mg84,00€10mg113,00€25mg177,00€50mg295,00€100mg447,00€200mg650,00€1mL*10mM (DMSO)93,00€Verbascoside
CAS :Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formule :C29H36O15Degré de pureté :97.46% - 99.55%Couleur et forme :SolidMasse moléculaire :624.59Ref: TM-T3375
2mg39,00€5mg58,00€10mg88,00€25mg168,00€50mg255,00€100mg359,00€200mg525,00€1mL*10mM (DMSO)81,00€CAY10404
CAS :CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.Formule :C17H12F3NO3SDegré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :367.34Picroside II
CAS :Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formule :C23H28O13Degré de pureté :98% - 99.83%Couleur et forme :SolidMasse moléculaire :512.46Desmethylanethol trithione
CAS :Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.
Formule :C9H6OS3Degré de pureté :98.05% - 98.41%Couleur et forme :SolidMasse moléculaire :226.34ONC212
CAS :ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.Formule :C24H23F3N4ODegré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :440.46β-Ionone
CAS :β-Ionone (β-lonone) is an end-ring analog of β-carotenoids which widely distributed in fruit and vegetables,with anti-proliferative, anti-metastaticFormule :C13H20ODegré de pureté :98.52%Couleur et forme :Colourless Liquid OilyMasse moléculaire :192.3GS-444217
CAS :GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).Formule :C23H21N7ODegré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :411.46OUL35
CAS :OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Formule :C14H12N2O3Degré de pureté :99.2%Couleur et forme :SolidMasse moléculaire :256.26TCPOBOP
CAS :TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.Formule :C16H8Cl4N2O2Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :402.06B355252
CAS :B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.Formule :C25H24ClN3O3S2Degré de pureté :98.73% - 99.92%Couleur et forme :SolidMasse moléculaire :514.06PD0166285
CAS :PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.Formule :C26H27Cl2N5O2Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :512.43AC1NS4RE
CAS :It is a tyrosine kinase inhibitor.Formule :C15H13ClN2ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :272.73Acacetin
CAS :Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormule :C16H12O5Degré de pureté :96.26% - ≥95%Couleur et forme :Pale-Yellow NeedlesMasse moléculaire :284.26VK3-OCH3
CAS :VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.Formule :C14H14O3SDegré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :262.32CAY10505
CAS :CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Formule :C14H8FNO3SDegré de pureté :99.69% - 99.74%Couleur et forme :SolidMasse moléculaire :289.28Ref: TM-T6433
10mg34,00€25mg52,00€50mg96,00€100mg144,00€200mg205,00€500mg350,00€1mL*10mM (DMSO)38,00€MRS 2578
CAS :MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.Formule :C20H20N6S4Degré de pureté :97.58% - 99.73%Couleur et forme :White SolidMasse moléculaire :472.67Polyphyllin I
CAS :Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Formule :C44H70O16Degré de pureté :98% - 99.5%Couleur et forme :SolidMasse moléculaire :855.02Epothilone A
CAS :Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.Formule :C26H39NO6SDegré de pureté :99.89% - 99.92%Couleur et forme :SolidMasse moléculaire :493.66Fedratinib hydrochloride hydrate
CAS :Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formule :C27H40Cl2N6O4SDegré de pureté :98.96% - 99.87%Couleur et forme :SolidMasse moléculaire :615.61G5-7
CAS :G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formule :C22H19F2NO3Degré de pureté :97.3%Couleur et forme :SolidMasse moléculaire :383.39Ref: TM-T8742
1mg35,00€5mg71,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€1mL*10mM (DMSO)78,00€Alginic acid
CAS :Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.Formule :C14H22O13Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :398.317OTS514 hydrochloride
CAS :OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).Formule :C21H20N2O2S·HClDegré de pureté :99.67% - 99.84%Couleur et forme :SolidMasse moléculaire :400.92Ref: TM-T4134
1mg58,00€2mg92,00€5mg165,00€10mg290,00€25mg527,00€50mg710,00€100mg898,00€500mg1.791,00€1mL*10mM (DMSO)165,00€Kynurenic acid sodium
CAS :Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.Formule :C10H6NNaO3Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :211.15MK-886
CAS :MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Formule :C27H34ClNO2SDegré de pureté :99.23% - 99.84%Couleur et forme :SolidMasse moléculaire :472.08Ref: TM-T6893
1mg35,00€5mg70,00€10mg111,00€25mg216,00€50mg354,00€100mg540,00€200mg772,00€1mL*10mM (DMSO)72,00€Xanthatin
CAS :Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formule :C15H18O3Degré de pureté :98.48% - 99.96%Couleur et forme :SolidMasse moléculaire :246.3CASIN
CAS :CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formule :C20H22N2ODegré de pureté :98.18% - >99.99%Couleur et forme :SolidMasse moléculaire :306.4Ref: TM-T3971
1mg35,00€2mg50,00€5mg71,00€10mg114,00€25mg178,00€50mg268,00€100mg413,00€500mg888,00€1mL*10mM (DMSO)71,00€NU 7026
CAS :NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibitionFormule :C17H15NO3Degré de pureté :99.51% - >99.99%Couleur et forme :SolidMasse moléculaire :281.314EGI-1
CAS :4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formule :C18H12Cl2N4O4SDegré de pureté :96.8% - 99.12%Couleur et forme :SolidMasse moléculaire :451.28Lithocholic acid
CAS :Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Formule :C24H40O3Degré de pureté :98% - 99.93%Couleur et forme :Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Masse moléculaire :376.57SKF-96365 hydrochloride
CAS :SKF-96365 hydrochloride (SKF96365) , a SOCE inhibitor, exhibits potent anti-neoplastic activity by inducing cell-cycle arrest and apoptosis in colorectal YFormule :C22H27ClN2O3Degré de pureté :99.47% - 99.92%Couleur et forme :SolidMasse moléculaire :402.91Ref: TM-T2170
5mg54,00€10mg81,00€25mg131,00€50mg230,00€100mg445,00€200mg680,00€500mg1.054,00€1mL*10mM (DMSO)59,00€
