Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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LYN-1604 dihydrochloride
CAS :LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.Formule :C33H45Cl4N3O2Degré de pureté :98.95% - 99.92%Couleur et forme :SolidMasse moléculaire :657.54Ref: TM-T8808L
1mg35,00€5mg78,00€1mL*10mM (DMSO)101,00€10mg117,00€25mg212,00€50mg316,00€100mg447,00€200mg628,00€Azadirachtin
CAS :Azadirachtin has antifungal activity, used as an insecticide.Formule :C35H44O16Degré de pureté :98.11% - 99.713%Couleur et forme :SolidMasse moléculaire :720.71Polyphyllin VI
CAS :1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.Formule :C39H62O13Degré de pureté :99.69% - 99.72%Couleur et forme :SolidMasse moléculaire :738.90Ref: TM-T6S2315
1mg37,00€5mg71,00€10mg90,00€1mL*10mM (DMSO)103,00€25mg147,00€50mg208,00€100mg309,00€200mg447,00€TCS JNK 5a
CAS :TCS JNK 5a (SC202671) is an effective, specific inhibitor of JNK3(pIC50= 6.7), JNK2(pIC50=6.5).Formule :C20H16N2OSDegré de pureté :99.22% - 99.51%Couleur et forme :SolidMasse moléculaire :332.42Prexasertib dihydrochloride
CAS :Prexasertib dihydrochloride (LY2606368) inhibits CHK1 (Ki: 0.9 nM); IC50: CHK2 8 nM, RSK 9 nM.Formule :C18H21Cl2N7O2Degré de pureté :98.46% - 99.82%Couleur et forme :SolidMasse moléculaire :438.31Ref: TM-T4327
1mg43,00€2mg56,00€5mg93,00€1mL*10mM (DMSO)96,00€10mg137,00€25mg259,00€50mg405,00€100mg597,00€500mg1.251,00€Sophoraflavanone G
CAS :Sophoraflavanone G (Kushenol F) (Kushenol F), isolated from Sophora flavescens, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-relatedFormule :C25H28O6Degré de pureté :97.09% - 99.77%Couleur et forme :SolidMasse moléculaire :424.49Importazole
CAS :Importazole is an inhibitor of the nuclear transport receptor importin-β.Formule :C20H22N4Degré de pureté :99.6% - >99.99%Couleur et forme :SolidMasse moléculaire :318.42Ref: TM-T3445
5mg49,00€1mL*10mM (DMSO)54,00€10mg69,00€25mg144,00€50mg215,00€100mg356,00€200mg532,00€500mg852,00€3,4-Dicaffeoylquinic acid
CAS :3,4-Dicaffeoylquinic acid (Isochlorogenic acid B) has antioxidant activity.Formule :C25H24O12Degré de pureté :96.33% - 98.82%Couleur et forme :SolidMasse moléculaire :516.45Ref: TM-T6S1525
1mg40,00€5mg80,00€10mg101,00€1mL*10mM (DMSO)103,00€25mg167,00€50mg240,00€100mg355,00€500mg845,00€PROCYANIDIN C1
CAS :Procyanidin C1 is a natural polyphenol. It reduces Bcl-2 protein levels.Cost-effective and quality-assured.Formule :C45H38O18Degré de pureté :97.01% - 99.86%Couleur et forme :SolidMasse moléculaire :866.77Ref: TM-TN2103
1mg74,00€5mg289,00€10mg447,00€1mL*10mM (DMSO)462,00€25mg760,00€50mg1.018,00€100mg1.378,00€ICCB-19 hydrochloride
CAS :ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.Formule :C12H22ClN3OSDegré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :291.84Ref: TM-T8931L
5mg34,00€1mL*10mM (DMSO)34,00€10mg50,00€25mg90,00€50mg138,00€100mg198,00€200mg296,00€500mg469,00€ON1231320
CAS :ON1231320 (GBO-006) is a Polo-like kinase 2 (PLK2) inhibitor.Formule :C22H15F2N5O3SDegré de pureté :97.31%Couleur et forme :SolidMasse moléculaire :467.45Ref: TM-T19664
1mg46,00€5mg88,00€1mL*10mM (DMSO)95,00€10mg132,00€25mg259,00€50mg404,00€100mg592,00€200mg843,00€Pictilisib
CAS :Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Formule :C23H27N7O3S2Degré de pureté :98.69% - 99.97%Couleur et forme :SolidMasse moléculaire :513.64Aristolactam I
CAS :Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway.Formule :C17H11NO4Degré de pureté :98.98% - 99.96%Couleur et forme :SolidMasse moléculaire :293.27Ref: TM-T3S1227
1mg57,00€5mg133,00€1mL*10mM (DMSO)172,00€10mg205,00€25mg350,00€50mg515,00€100mg735,00€Nimustine Hydrochloride
CAS :Nimustine Hydrochloride (Nidran hydrochloride) has been used in trials studying the treatment of Glioblastoma.Formule :C9H14Cl2N6O2Degré de pureté :98.80%Couleur et forme :SolidMasse moléculaire :309.15Ref: TM-T5017
2mg34,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg71,00€25mg92,00€50mg152,00€100mg268,00€200mg398,00€LQZ-7I
CAS :LQZ-7I is an inhibitor of surviving-targeting. It orally effectively inhibits xenograft tumor growth and induces survivin loss in tumorsFormule :C20H14F2N4Degré de pureté :99.81% - 99.87%Couleur et forme :SolidMasse moléculaire :348.35Liensinine
CAS :1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.Formule :C37H42N2O6Degré de pureté :98.92% - 99.93%Couleur et forme :White-Like PowderMasse moléculaire :610.74Mollugin
CAS :Mollugin could be a JAK2 inhibitor, anti-inflammatory, chemotherapeutic agent in OSCCs, bone disorder therapy, and modulates HER2 in cancer.Formule :C17H16O4Degré de pureté :99.87% - ≥95%Couleur et forme :SolidMasse moléculaire :284.31Atorvastatin hemicalcium salt
CAS :Atorvastatin hemicalcium salt (Atorvastatin Calcium) is an orally HMG-CoA reductase inhibitor that lowers cholesterol. Cost-effective and quality-assured.Formule :C33H34FN2O5CaDegré de pureté :99.27% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :577.67Bafilomycin A1
CAS :Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Formule :C35H58O9Degré de pureté :95.87% - 99.36%Couleur et forme :SolidMasse moléculaire :622.83Karanjin
CAS :Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.Formule :C18H12O4Degré de pureté :99.01%Couleur et forme :SolidMasse moléculaire :292.29Ref: TM-T2S0820
1mg46,00€1mL*10mM (DMSO)94,00€5mg96,00€10mg145,00€25mg259,00€50mg385,00€100mg557,00€200mg790,00€Picropodophyllin
CAS :Picropodophyllin (PPP) is a selective IGF-1R inhibitor with IC50 of 1 nM, not affecting other growth factor receptors.Formule :C22H22O8Degré de pureté :98.38% - 99.83%Couleur et forme :SolidMasse moléculaire :414.41Ref: TM-T6943
5mg64,00€1mL*10mM (DMSO)69,00€10mg88,00€25mg170,00€50mg316,00€100mg535,00€500mg1.121,00€Madecassoside
CAS :Madecassoside (Asiaticoside A) is a pentacyclic triterpene extracted from Centella asitica (L.) with anti-inflammatory, anti-oxidative and anti-aging activitiesFormule :C48H78O20Degré de pureté :99.46% - 99.85%Couleur et forme :White PowderMasse moléculaire :975.12Ref: TM-T2813
10mg49,00€1mL*10mM (DMSO)49,00€25mg84,00€50mg120,00€100mg178,00€200mg289,00€500mg485,00€PFK-158
CAS :PFK-158 is an effective and specific inhibitor PFKFB3.Formule :C18H11F3N2ODegré de pureté :95.49% - 99.16%Couleur et forme :SolidMasse moléculaire :328.29Ref: TM-T3105
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg90,00€25mg170,00€50mg259,00€100mg409,00€Z-FA-FMK
CAS :Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.Formule :C21H23FN2O4Degré de pureté :98.84% - 99.68%Couleur et forme :SolidMasse moléculaire :386.42Desoxyrhaponticin
CAS :Deoxyrhaponticin may reduce post-meal blood sugar and inhibit cancer cell growth.Formule :C21H24O8Degré de pureté :99.97% - ≥95%Couleur et forme :SolidMasse moléculaire :404.41Ref: TM-TJS0387
1mg46,00€5mg84,00€1mL*10mM (DMSO)90,00€10mg126,00€25mg260,00€50mg385,00€100mg560,00€200mg790,00€SU9516
CAS :SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.Formule :C13H11N3O2Degré de pureté :99.34% - 99.96%Couleur et forme :SolidMasse moléculaire :241.25Ref: TM-T6167
1mg34,00€2mg48,00€5mg70,00€1mL*10mM (DMSO)71,00€10mg98,00€25mg197,00€50mg356,00€100mg530,00€500mg1.153,00€Erastin
CAS :Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner, anti-tumor. High-Quality, Low-Cost!Formule :C30H31ClN4O4Degré de pureté :98% - 99.82%Couleur et forme :SolidMasse moléculaire :547.04Ref: TM-T1765
1mg46,00€2x1mg59,00€5x1mg93,00€10x1mg120,00€25x1mg192,00€50x1mg284,00€100x1mg421,00€200x1mg618,00€Zinc Protoporphyrin
CAS :Zinc Protoporphyrin is an oral HO-1 inhibitor that reduces PG's protection against H2O2 and has anti-cancer properties.Formule :C34H32N4O4ZnDegré de pureté :95.43% - 99.27%Couleur et forme :SolidMasse moléculaire :626.02A-1155463
CAS :A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2, BCL-W and MCL-1.Formule :C35H32FN5O4S2Degré de pureté :96.1% - 99%Couleur et forme :SolidMasse moléculaire :669.79PI-1840
CAS :PI-1840 is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and PGPH-L.Formule :C22H26N4O3Degré de pureté :98.82%Couleur et forme :SolidMasse moléculaire :394.47Cynaroside
CAS :Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.Formule :C21H20O11Degré de pureté :98% - >99.99%Couleur et forme :SolidMasse moléculaire :448.38Ref: TM-T3376
1mg34,00€5mg71,00€1mL*10mM (DMSO)80,00€10mg98,00€25mg192,00€50mg339,00€100mg505,00€200mg717,00€Linderalactone
CAS :1. Linderalactone showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, values of IC5 is 8.48 μg/mL.Formule :C15H16O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :244.29Ref: TM-T5S1897
1mg43,00€5mg84,00€1mL*10mM (DMSO)102,00€10mg119,00€25mg197,00€50mg294,00€100mg437,00€TVB-3166
CAS :TVB-3166: reversible, selective FASN inhibitor, induces apoptosis, hinders xenograft growth (IC50: 42 nM FASN, 81 nM palmitate synthesis).Formule :C24H24N4ODegré de pureté :99.53% - 99.57%Couleur et forme :SolidMasse moléculaire :384.47Ref: TM-T17180
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg110,00€25mg195,00€50mg334,00€100mg500,00€Sirtinol
CAS :Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Formule :C26H22N2O2Degré de pureté :97.12% - 99.96%Couleur et forme :SolidMasse moléculaire :394.47Ref: TM-T6671
2mg40,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg88,00€25mg170,00€50mg324,00€100mg482,00€500mg1.063,00€VER-50589
CAS :VER-50589 is a potent HSP90 inhibitor.Formule :C19H17ClN2O5Degré de pureté :99.96% - >99.99%Couleur et forme :SolidMasse moléculaire :388.8Ref: TM-T2258
1mg39,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg150,00€25mg250,00€50mg384,00€100mg557,00€200mg787,00€GSK 3 Inhibitor IX
CAS :GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.Formule :C16H10BrN3O2Degré de pureté :98% - 99.72%Couleur et forme :SolidMasse moléculaire :356.17Ref: TM-T1917
1mg42,00€2mg52,00€5mg78,00€1mL*10mM (DMSO)86,00€10mg96,00€25mg216,00€50mg389,00€100mg577,00€500mg1.234,00€FR 180204
CAS :FR 180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.Formule :C18H13N7Degré de pureté :98% - 99.74%Couleur et forme :SolidMasse moléculaire :327.34Ref: TM-T1956
1mg40,00€2mg52,00€5mg81,00€1mL*10mM (DMSO)89,00€10mg131,00€25mg210,00€50mg314,00€100mg470,00€MSC 2032964A
CAS :MSC 2032964A: Potent, selective ASK1 inhibitor, IC50=93 nM, oral, brain-permeable, curbs neuroinflammation, blocks LPS-induced ASK1/p38 activation.
Formule :C16H13F3N6ODegré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :362.31Ref: TM-T33514
1mg84,00€2mg97,00€5mg158,00€10mg240,00€25mg393,00€50mg560,00€100mg753,00€200mg1.035,00€CHS-828
CAS :CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Formule :C19H22ClN5ODegré de pureté :98% - 99.9%Couleur et forme :SolidMasse moléculaire :371.86LW6
CAS :LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor.Formule :C26H29NO5Degré de pureté :98.1% - 98.22%Couleur et forme :SolidMasse moléculaire :435.51Ref: TM-T3494
2mg44,00€5mg65,00€1mL*10mM (DMSO)65,00€10mg94,00€25mg173,00€50mg281,00€100mg424,00€500mg888,00€Wogonin
CAS :Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.Formule :C16H12O5Degré de pureté :98% - 99.8%Couleur et forme :Yellow CrystalMasse moléculaire :284.26Ref: TM-T2933
5mg34,00€10mg42,00€1mL*10mM (DMSO)52,00€25mg59,00€50mg92,00€100mg131,00€200mg178,00€500mg309,00€Formosanin C
CAS :Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.Formule :C51H82O20Degré de pureté :98.98% - >99.99%Couleur et forme :SolidMasse moléculaire :1015.18Cyasterone
CAS :Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promisingFormule :C29H44O8Degré de pureté :99.32% - 99.70%Couleur et forme :SolidMasse moléculaire :520.65Stattic
CAS :Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation.Formule :C8H5NO4SDegré de pureté :98.32% - 99.76%Couleur et forme :SolidMasse moléculaire :211.19Ref: TM-T6308
5mg35,00€10mg51,00€1mL*10mM (DMSO)55,00€25mg85,00€50mg124,00€100mg187,00€200mg279,00€500mg465,00€Pifithrin-α hydrobromide
CAS :Pifithrin-α hydrobromide (Pifithrin-α hydrobromide) is a p53 inhibitor, inhibiting p53-dependent transactivation of p53-responsive genes.Formule :C16H18N2OS·HBrDegré de pureté :97.71% - >99.99%Couleur et forme :SolidMasse moléculaire :367.3SGI-1027
CAS :SGI-1027 (DNA Methyltransferase Inhibitor II) is an effective and selective inhibitor of DNA methyltransferase (DNMT).Formule :C27H23N7ODegré de pureté :99.45% - 99.78%Couleur et forme :SolidMasse moléculaire :461.52Ref: TM-T1904
5mg58,00€1mL*10mM (DMSO)74,00€10mg94,00€25mg163,00€50mg296,00€100mg467,00€500mg1.035,00€RO8994
CAS :RO8994: potent MDM2 spiroindolinone inhibitor, IC50: 20 nM (proliferation), 5 nM (binding).Formule :C31H31Cl2FN4O4Degré de pureté :99.31% - 99.44%Couleur et forme :SolidMasse moléculaire :613.51Ref: TM-T3517
1mg38,00€2mg50,00€5mg82,00€1mL*10mM (DMSO)100,00€10mg120,00€25mg219,00€50mg344,00€100mg512,00€Rotenone
CAS :Rotenone, a plant-derived insecticide, inhibits mitochondrial electron transport, found in Leguminosae.Formule :C23H22O6Degré de pureté :89.58% - 99.88%Couleur et forme :Less To Brownish Crystals Or A White To Brownish-White Crystalline Powder Has Neither Odor Nor Taste (Ntp 1992)Masse moléculaire :394.42Epibrassinolide
CAS :Epibrassinolide (BP55) (EBR) is a biologically active compound of the brassinosteroids, is a natural brassinosteroid (BR) derivative, is a plant regulator withFormule :C28H48O6Degré de pureté :97.57% - 98.11%Couleur et forme :SolidMasse moléculaire :480.68PIK-75
CAS :PIK-75, a DNA-PK and PI3K inhibitor, suppresses DNA-PK(IC50=2 nM), p110α(IC50=5.8 nM) and p110γ(IC50=76 nM).
Formule :C16H14BrN5O4SDegré de pureté :98.52% - >99.99%Couleur et forme :SolidMasse moléculaire :452.28
