Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(6 produits)
- BCL(11 produits)
- Caspase(125 produits)
- FOXO1(3 produits)
- IAP(66 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(125 produits)
- PDK(9 produits)
- PERK(25 produits)
- Sérine/thréonine kinase(15 produits)
- Survivant(13 produits)
- TNF(92 produits)
- c-RET(51 produits)
- p53(62 produits)
Affichez 6 plus de sous-catégories
5600 produits trouvés pour "Apoptose"
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RET-IN-23
CAS :<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Formule :C28H28FN11Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :537.59NLRP3/AIM2-IN-3
CAS :<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Formule :C16H14N2O2Degré de pureté :97.04%Couleur et forme :SolidMasse moléculaire :266.29Anticancer agent 110
CAS :<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Formule :C18H13FN6OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.4STAT3-IN-13
CAS :<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Formule :C21H20N6O3SDegré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :436.49AOH1160
CAS :<p>AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).</p>Formule :C25H20N2O3Degré de pureté :98.46% - 99.52%Couleur et forme :SolidMasse moléculaire :396.44TT01001
CAS :<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Formule :C15H19Cl2N3O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :376.3NecroX-7
CAS :<p>NecroX-7 (LC-280126) is a potent free radical scavenger and a HMGB1 (high-mobility group box 1) inhibitor.</p>Formule :C24H29N3O3SDegré de pureté :98.22%Couleur et forme :SolidMasse moléculaire :439.57Triparanol
CAS :<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Formule :C27H32ClNO2Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :438SLMP53-1
CAS :<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Formule :C20H18N2O2Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :318.37LQZ-7F
CAS :<p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>Formule :C14H7N9O3Degré de pureté :98.64%Couleur et forme :SolidMasse moléculaire :349.26CBS9106
CAS :<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Formule :C18H21ClF3N3O3Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :419.83H2L5186303
CAS :<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Formule :C26H20N2O8Degré de pureté :98.19%Couleur et forme :SolidMasse moléculaire :488.45D609
CAS :<p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>Formule :C11H15KOS2Degré de pureté :97.67% - 99.56%Couleur et forme :Off-White PowderMasse moléculaire :266.46Tubulin inhibitor 11
CAS :<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Formule :C22H23N3O3SDegré de pureté :98.32%Couleur et forme :SoildMasse moléculaire :409.5CMLD-2
CAS :<p>CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.</p>Formule :C31H31NO6Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :513.58NM-3
CAS :<p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>Formule :C13H12O6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :264.23ZDLD20
CAS :<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Formule :C22H22N6ODegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :386.45OR-1896
CAS :<p>OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.</p>Formule :C13H15N3O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :245.28MJN68390
CAS :<p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>Formule :C24H28ClN3O3Degré de pureté :98.86%Couleur et forme :SolidMasse moléculaire :441.95Etomoxir
CAS :<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Formule :C17H23ClO4Degré de pureté :98% - 99.39%Couleur et forme :SolidMasse moléculaire :326.82P505-15 Acetate
CAS :<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Formule :C21H27N9O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :453.5K-8012
CAS :<p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>Formule :C23H23FN4Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :374.45DCG066
CAS :<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Formule :C30H31F6N3O2Degré de pureté :98.26% - 98.38%Couleur et forme :SolidMasse moléculaire :579.58Cot inhibitor-1
CAS :<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Formule :C27H27Cl2FN8Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :553.46Pyrazoloacridine
CAS :<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Formule :C19H21N5O3Degré de pureté :99.72%Couleur et forme :SolidMasse moléculaire :367.4Ro 08-2750
CAS :<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Formule :C13H10N4O3Degré de pureté :98.795%Couleur et forme :SolidMasse moléculaire :270.24Minodronic acid
CAS :Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.Formule :C9H12N2O7P2Degré de pureté :98.02%Couleur et forme :SolidMasse moléculaire :322.15Epristeride
CAS :<p>Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.</p>Formule :C25H37NO3Degré de pureté :98.12% - >99.99%Couleur et forme :SolidMasse moléculaire :399.571G244
CAS :<p>1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.</p>Formule :C29H30F2N4O2Degré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :504.57Trk-IN-9
CAS :<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Formule :C23H24ClFN6ODegré de pureté :98.15%Couleur et forme :SolidMasse moléculaire :454.93Mepazine
CAS :<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Formule :C19H22N2SDegré de pureté :99.88% - 99.92%Couleur et forme :SolidMasse moléculaire :310.46Perphenazine dihydrochloride
CAS :<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Formule :C21H28Cl3N3OSDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :476.89Cipepofol
CAS :<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Formule :C14H20ODegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :204.31SYM 2081
CAS :<p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>Formule :C6H11NO4Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :161.16BC 11 hydrobromide
CAS :<p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>Formule :C8H12BBrN2O2SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :290.97RIPK3-IN-1
CAS :<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Formule :C29H25FN4O4Degré de pureté :98.27%Couleur et forme :SolidMasse moléculaire :512.53Ro 90-7501
CAS :<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Formule :C20H16N6Degré de pureté :97.21% - 99.72%Couleur et forme :SolidMasse moléculaire :340.38FA16
<p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>Formule :C22H27F3N4O2SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :468.54BCP-T.A
CAS :<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Formule :C23H19Cl2N3OSDegré de pureté :99.49%Couleur et forme :SolidMasse moléculaire :456.39Gallium maltolate
CAS :<p>Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.</p>Formule :C18H15GaO9Degré de pureté :99.61% - 99.67%Couleur et forme :SolidMasse moléculaire :445.03MBM-55
CAS :<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Formule :C28H27FN6O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :498.55Deferitazole
CAS :<p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>Formule :C18H25NO7SDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :399.46N6-Cyclopentyladenosine
CAS :<p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>Formule :C15H21N5O4Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :335.36UCB-5307
CAS :<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Formule :C22H21N3ODegré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :343.42AMG PERK 44
CAS :<p>AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.</p>Formule :C34H29ClN4O2Degré de pureté :98.8% - 99.81%Couleur et forme :SolidMasse moléculaire :561.07AQ4
CAS :<p>AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.</p>Formule :C22H28N4O4Degré de pureté :96.28% - 97.15%Couleur et forme :SolidMasse moléculaire :412.48DB1976
CAS :<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Formule :C20H16N8SeDegré de pureté :98.74%Couleur et forme :SolidMasse moléculaire :447.35HTH-01-091
CAS :<p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>Formule :C26H28Cl2N4O2Degré de pureté :98.4%Couleur et forme :SolidMasse moléculaire :499.43HBED
CAS :<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Formule :C20H24N2O6Degré de pureté :97.35% - 98.58%Couleur et forme :SolidMasse moléculaire :388.41KR-33493
CAS :<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Formule :C20H18BrN3O3SDegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :460.34
