Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(11 produits)
- Caspase(144 produits)
- FOXO1(3 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(139 produits)
- PDK(9 produits)
- PERK(26 produits)
- Sérine/thréonine kinase(19 produits)
- Survivant(14 produits)
- TNF(91 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6038 produits trouvés pour "Apoptose"
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AK-295
CAS :AK 295, also known as CX 295, is a dipeptide inhibitor of alpha-ketoamide calpain.Formule :C26H40N4O6Couleur et forme :SolidMasse moléculaire :504.62Antitumor agent-76
CAS :Antitumor agent-76 is a water-soluble, orally active, rapid-release prodrug of Triptolide that exhibits anticancer effects.Formule :C28H36ClNO10Couleur et forme :SolidMasse moléculaire :582.04Anticancer agent 69
Anticancer agent 69 targets PC3 cells (IC50=26 nM), raises ROS, lowers EGFR, and induces apoptosis.Formule :C19H26N8SCouleur et forme :SolidMasse moléculaire :398.53Ph-Ph+
Ph-Ph+ is a dimerized phenanthroline derivative with antitumor, antibacterial, and antifungal effects.Formule :C24H17N4Couleur et forme :SolidMasse moléculaire :361.42TNF-α-IN-2
CAS :TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.Formule :C25H21ClF2N6ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :494.92Antiproliferative agent-63
CAS :Antiproliferative agent-63 (compound 4d) is a cyclic analog of cannabidiol that acts as an anticancer agent. It demonstrates favorable activity against breast and colorectal cancer. Moreover, this compound can arrest the cell cycle in the G1 phase and induce apoptosis through the mitochondrial pathway in breast cancer cell lines.Formule :C27H41NO2Couleur et forme :SolidMasse moléculaire :411.62TLBC
CAS :TLBC, a borane-chalcone derivative, exhibits dose-dependent inhibitory effects across various glioma cell lines with IC50 values ranging from 5.5 to 25.5 μM. TLBC induces apoptosis independently of alterations in the tumor suppressor factor p53.Formule :C15H12BIO3Couleur et forme :SolidMasse moléculaire :377.97Etalocib sodium
CAS :Etalocib (LY293111) sodium is an orally active leukotriene B4 (LTB4) receptor antagonist with a Ki value of 25 nM for inhibiting [3H]LTB4 binding. It exhibits an IC50 of 20 nM against LTB4-induced calcium mobilization. Additionally, Etalocib sodium can induce apoptosis.Formule :C33H32FNaO6Couleur et forme :SolidMasse moléculaire :566.59JNK-IN-19
CAS :JNK-IN-19 (Compound Q8) is an inhibitor of c-Jun N-terminal kinase, utilized for the treatment and/or prevention of injuries prior to, during, or following surgery.Formule :C22H24F3N6Na2O6PCouleur et forme :SolidMasse moléculaire :602.41YW3-56 (hydrochloride) (technical grade)
CAS :YW3-56: PAD2 & PAD4 inhibitor (IC50 = 0.5-5 μM), halts U2OS cell growth (IC50 ~2.5 μM), reduces S-180 & MDA-MB-231 tumor growth in mice.Formule :C27H33Cl2N5O2Couleur et forme :SolidMasse moléculaire :530.49FKBP51-Hsp90-IN-2
CAS :FKBP51-Hsp90-IN-2 (Compound E08) functions as a selective inhibitor for the FKBP51 - Hsp90 protein-protein interaction, exhibiting IC 50 values of 0.4 µM for FKBP51 and 5 µM for FKBP52. Beyond its inhibitory actions, FKBP51-Hsp90-IN-2 enhances cellular energy metabolism and promotes neurite growth. This compound is utilized in the study of neurodegenerative diseases and cancer [1].Formule :C25H27N3O2SMasse moléculaire :433.57Antitumor agent-100
CAS :Antitumor Agent-100 (compound A6) is a molecular gel and apoptosis inducer targeting PDE3A-SLFN12 with an IC50 of 0.3 μM, demonstrating potent antitumor activity. This orally available agent binds to the PDE3A enzyme pocket, recruiting and stabilizing SLFN12 which disrupts protein translation and induces apoptosis [1].Formule :C17H14ClN3OMasse moléculaire :311.77Vitamin K5 hydrochloride
CAS :Vitamin K5 (hydrochloride), a naphthoquinone compound, exhibits trichomonacidal activity in vitro and can be utilized for anti-infection research [1].Formule :C11H12ClNOMasse moléculaire :209.67Anticancer agent 16
Anticancer agent 16 showed good cytotoxic effects on HCT-116 cell line (IC50: 8.55 μM), NCI-H460 cell line (IC50: 5.41 μM) and SKOV3 cell line (IC50: 6.4 μM).Formule :C27H33N5O6Couleur et forme :SolidMasse moléculaire :523.58Utibaprilat
CAS :Utibaprilat is the primary degradation product of Utibapril and functions as an ACE inhibitor.Formule :C20H27N3O5SCouleur et forme :SolidMasse moléculaire :421.51L5-DA
<p>L5-DA, a G-quadruplex ligand, stabilizes G4s in HeLa cells, induces apoptosis, and is cytotoxic with an IC50 of 4.3 μM.</p>Formule :C32H34N6O2Couleur et forme :SolidMasse moléculaire :534.65TBC-1
CAS :<p>TBC-1 is a chlorophyll-a derivative that acts as a photosensitizer for photodynamic therapy (PDT). It efficiently generates type I ROS and targets the endoplasmic reticulum. TBC-1 demonstrates in vitro biocompatibility and PDT effectiveness under both normoxic and hypoxic conditions.</p>Formule :C31H28BrN3O3Couleur et forme :SolidMasse moléculaire :570.476NA-17
CAS :<p>NA-17 is a naphthalimide compound with antitumor activity and exhibits lower toxicity to normal cells such as HL-7702 and WI-38. It demonstrates p53-dependent inhibition selectivity in various NSCLC cells, inducing the accumulation of active p53 in the mitochondria and nuclei of these cells. NA-17 causes cell cycle arrest in the G1 phase and promotes apoptosis and cell death.</p>Formule :C26H27N3O4Couleur et forme :SolidMasse moléculaire :445.51FHND5071 (1H)
CAS :FHND5071 (1H) is a selective inhibitor of RET (rearranged during transfection) tyrosine kinase. It shows potential for research applications in RET-driven cancers, such as thyroid and lung cancer.Formule :C30H33N9OCouleur et forme :SolidMasse moléculaire :535.64Cofpropamine
CAS :Cofpropamine, a caffeine derivative that inhibits polyadenylation, enhances the suppressive effects of Cyclophosphamide in animal models of rat adjuvant arthritis and mouse collagen-induced arthritis.Formule :C13H21N5O3Couleur et forme :SolidMasse moléculaire :295.34
