Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(140 produits)
- PDK(9 produits)
- PERK(24 produits)
- Sérine/thréonine kinase(19 produits)
- Survivant(14 produits)
- TNF(94 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6498 produits trouvés pour "Apoptose"
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TNF-α-IN-14
CAS :TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].Formule :C22H26O6Couleur et forme :SolidMasse moléculaire :386.44Antitumor agent-78
Antitumor agent-78 blocks GPx-4, raises COX2, triggers apoptosis, halts EMT, and stifles cancer cell growth and migration.Couleur et forme :SoildRIPK1-IN-24
CAS :RIPK1-IN-24 is an inhibitor of receptor-interacting protein kinase 1 (RIPK1) with an IC50 of 1.3 μM. It is utilized in research on inflammatory diseases.Formule :C26H21FN6O2Couleur et forme :SolidMasse moléculaire :468.48Nenocorilant
CAS :Nenocorilant (Relacorilant) is an orally active glucocorticoid receptor (GR) antagonist (Ki: 0.15 nM). Nenocorilant can be used to study tumours.Formule :C26H21F4N7O3SCouleur et forme :SolidMasse moléculaire :587.55DOR agonist 2
CAS :Compound 3 (DOR agonist 2) acts as a Delta Opioid Receptor agonist. It inhibits the expression of TNF-α, obstructs NF-κB transportation to the nucleus, and activates the G protein-mediated ERK1/2 pathway. This compound is useful for research into neurodegenerative diseases.Formule :C29H26N2O3Couleur et forme :SolidMasse moléculaire :450.53PKM2-IN-6
CAS :PKM2-IN-6 (compound 7d) is an orally active PKM2 inhibitor (IC50=23 nM) capable of inducing apoptosis and G2 cell cycle arrest. It reduces PKM1 and PKM2 expression at the mRNA level, exhibits antitumour activity, and is suitable for investigating triple-negative breast cancer (TNBC).Formule :C17H14N4OSDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :322.38Tubulin inhibitor 43
CAS :Tubulin inhibitor 43 exhibits significant antitumor activity by impeding the proliferation and growth of cancer cells through the inhibition of β-microtubulin activity, ultimately inducing apoptosis [1].Formule :C20H21NO6Couleur et forme :SolidMasse moléculaire :371.38ADH-6
CAS :ADH-6, a tripyridylamide, disrupts mutant p53 aggregates in cancer cells, reviving its function and inducing apoptosis.Formule :C29H36N8O9Couleur et forme :SolidMasse moléculaire :640.64JR5-26B
CAS :JR5-26B is an orally active apoptosis (apoptosis) inducer. It induces cell death via copper-mediated apoptosis and necroptosis (necroptosis). JR5-26B exhibits antiproliferative activity against MIA PaCa-2, PANC-1, PAN02, SU.86.86, and KPC-2 cells, with IC50 values of 0.6, 4.4, 8.0, 1.1, and 3.4 μM, respectively.Formule :C19H17FN6OCouleur et forme :SolidMasse moléculaire :364.38XIAP degrader-1
XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).Formule :C34H45N5O4Couleur et forme :SolidMasse moléculaire :587.75(Rac)-Idroxioleic acid sodium
CAS :(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) sodium is a synthetic derivative of oleic acid (OA) that binds to the plasma membrane, altering lipid composition. This compound exhibits antitumor properties.Formule :C18H33NaO3Couleur et forme :SolidMasse moléculaire :320.44Antitumor agent-184
CAS :Antitumor Agent-184 (compound 12aa) triggers apoptosis in various cell lines, exhibiting IC50 values of 2.35 μM in B16-F10 cells, 7.32 μM in 4T1 cells, and 10.31 μM in CT26 cells.Formule :C22H16N4O2SCouleur et forme :SolidMasse moléculaire :400.45TOPOI/PARP-1-IN-1
CAS :Compound B6, also known as TOPOI/PARP-1-IN-1, is a dual inhibitor targeting TOPOI and PARP, exhibiting low cytotoxicity and oral activity with a PARP1 IC 50 of 0.09 μM. This compound effectively inhibits cancer cell proliferation and migration, induces cell cycle arrest at the G0/G1 phase, and triggers apoptosis. In murine models, TOPOI/PARP-1-IN-1 demonstrated a tumor growth inhibition rate (TGI) of 75.4% [1].Formule :C36H38Br2N4O2Couleur et forme :SolidMasse moléculaire :718.52(2R,3S)-Emricasan
CAS :(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan. This compound acts as an orally effective irreversible pan-caspase inhibitor. (2R,3S)-Emricasan inhibits the increase in caspase-3 activity induced by Zika virus (ZIKV) and protects human cortical neural progenitor cells.Formule :C26H27F4N3O7Couleur et forme :SolidMasse moléculaire :569.5TNF-α-IN-2
CAS :TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.Formule :C25H21ClF2N6ODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :494.92Aplysin
CAS :Aplysin suppresses breast cancer cells and protects liver cells by blocking PI3K/AKT/FOXO3a and preventing oxidative damage.Formule :C15H19BrOCouleur et forme :SolidMasse moléculaire :295.21Thalidomide-NH-amido-PEG2-C2-NH2
CAS :Thalidomide-NH-amido-PEG2-C2-NH2 is a synthetic E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. It is utilized in the synthesis of PROTACs.Formule :C21H27N5O7Masse moléculaire :461.47Kahweol Acetate
CAS :Kahweol Acetate, a semi-synthetic coffee bean derivative, inhibits osteoclasts, cancer cells, DNA damage, and oxidative stress.Formule :C22H28O4Couleur et forme :SolidMasse moléculaire :356.46Zharp1-211
CAS :Zharp1-211 is a RIPK3 inhibitor，reduces JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, (GVHD) for gastrointestinal inflammation.Formule :C24H25N5O4Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :447.49Ref: TM-T87664
1mg82,00€5mg173,00€1mL*10mM (DMSO)192,00€10mg268,00€25mg532,00€50mg827,00€100mg1.243,00€200mg1.674,00€Darizmetinib
CAS :Darizmetinib (HRX215) is an MKK4 inhibitor.Formule :C21H17F2N5O3SDegré de pureté :98.03% - 99.57%Couleur et forme :SolidMasse moléculaire :457.45Ref: TM-T72956
1mg69,00€2mg89,00€5mg147,00€1mL*10mM (DMSO)148,00€10mg224,00€25mg324,00€50mg400,00€100mg587,00€
