Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(134 produits)
- PDK(9 produits)
- PERK(23 produits)
- Sérine/thréonine kinase(17 produits)
- Survivant(14 produits)
- TNF(93 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6222 produits trouvés pour "Apoptose"
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PDE4B-IN-4
PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.Formule :C26H27N5O5Couleur et forme :SolidMasse moléculaire :489.52Opamtistomig
CAS :Opamtistomig is a humanized monoclonal antibody immunoglobulin (H-γ1-scFv-L-κ) dimer targeting human programmed death-ligand 1 (PD-L1), CD274, and tumor necrosis factor receptor superfamily member 9 (TNFRSF9). It is anticipated for use in research on various solid tumors and hematologic malignancies.Couleur et forme :Liquid(E/Z)-Eltrombopag 13C4
CAS :(E/Z)-Eltrombopag 13C4 is a mix of E/Z isotopologues, both 13C-labeled TPO receptor agonists for thrombocytopenia.Formule :C25H22N4O4Couleur et forme :SolidMasse moléculaire :446.444α-Tubulin polymerization-IN-1
α-Tubulin polymerization-IN-1 (Compound 8l) functions as an inhibitor of α-tubulin polymerization. This compound modulates the NRF2/KEAP-1 signaling pathway and induces ROS production in PC-3 cells, leading to apoptosis. It inhibits the proliferation of PC-3 cells with a GI50 of 0.17 µM, causing cell cycle arrest in the G2/M phase. Additionally, α-Tubulin polymerization-IN-1 demonstrates antitumor activity in mouse models.Couleur et forme :Odour SolidAntitumor agent-145
CAS :Compound Ir5 (Antitumor agent-145) serves as a tumor inhibitor characterized by significant fluorescence and mitochondrial targeting. It promotes anti-cancer activity by inducing necroptosis and stimulating the necroptosis-related immune response [1].Formule :C44H34IrN5OSCouleur et forme :SolidMasse moléculaire :873.06β-Glucuronide-dPBD-PEG5-NH2 TFA
CAS :β-Glucuronide-dPBD-PEG5-NH2 TFA is a β-glucuronide-linked pyrrolobenzodiazepine dimer employed in the synthesis of the antibody-drug conjugate (ADC) cIRCR201-Formule :C80H102F3N7O37Couleur et forme :SolidMasse moléculaire :1810.69Apoptosis inducer 3
CAS :Apoptosis Inducer 3 (Compound 3), a selective apoptosis triggering agent, induces both apoptosis and late-apoptosis phases, demonstrating cytotoxic effectsFormule :C49H55ClN2O7Couleur et forme :SolidMasse moléculaire :819.42FHD-286
CAS :FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.Formule :C24H30N6O6S2Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :562.66Ref: TM-T9749
1mg144,00€5mg283,00€1mL*10mM (DMSO)359,00€10mg454,00€25mg615,00€50mg777,00€100mg1.064,00€FOXO4-DRI
CAS :FOXO4-DRI: a peptide blocking FOXO4/p53 interaction; induces senescent cells' apoptosis.Formule :C228H388N86O64Couleur et forme :SolidMasse moléculaire :5358.06RET-IN-28
CAS :RET-IN-28 (Compound 16) is an inhibitor of RET (a transmembrane receptor tyrosine kinase). It specifically inhibits the activity of a mutant RET enzyme (RET-V804M) and is utilized in cancer research.Formule :C26H29N9Couleur et forme :SolidMasse moléculaire :467.57Zamzetoclax
CAS :Zamzetoclax (compound 1) acts as a potential inhibitor of Mcl-1.Formule :C38H46ClN5O6SCouleur et forme :SolidMasse moléculaire :736.32Ascochlorin
CAS :Ascochlorin, an isoprenoid antibiotic, inhibits STAT3 to combat tumors, induces apoptosis, and reduces inflammation.Formule :C23H29ClO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :404.93TPP-1 TFA
TPP-1 TFA is a high-affinity PD-L1 inhibitor (KD=95nM) that boosts T-cell function to curb tumor growth.Formule :C109H151F3N34O34S2Couleur et forme :SolidMasse moléculaire :2602.69Apoptosis inducer 37
Apoptosis inducer37 (Derivative 10) is an agent that induces apoptosis and exhibits anticancer properties by causing cell cycle arrest at the S-G2/M phase and promoting cell apoptosis. It significantly inhibits HCT116, SKOV3, and HepG2 cancer cells with IC50 values of 24.98 μM, 26.15 μM, and 23.09 μM, respectively. Apoptosis inducer37 demonstrates antitumor activity and can be utilized in ovarian cancer research.Formule :C27H37BrN2O4SCouleur et forme :SolidMasse moléculaire :564.16574Minocycline
CAS :Minocycline is a useful organic compound for research related to life sciences. The catalog number is T131626 and the CAS number is 10118-90-8.Formule :C23H27N3O7Couleur et forme :SolidMasse moléculaire :457.48Conglobatin
CAS :Conglobatin is a natural product for research related to life sciences. The catalog number is T36494 and the CAS number is 72263-05-9.Formule :C28H38N2O6Couleur et forme :SolidMasse moléculaire :498.62ASK1-IN-4
CAS :ASK1-IN-4 is an ASK1 inhibitor, IC50 = 0.2 μM.Formule :C18H14BrNO4S2Degré de pureté :99.756%Couleur et forme :SolidMasse moléculaire :452.34YL5084
CAS :YL5084 is a selective JNK2/3 inhibitor with IC50s: JNK2 (70 nM), JNK3 (84 nM), and antiproliferative, apoptosis-inducing effects.Formule :C35H36N8O2Couleur et forme :SolidMasse moléculaire :600.71EGFR/DHFR-IN-2
EGFR/DHFR-IN-2 (9b) is a dual inhibitor of h-DHFR/EGFR TK, exhibiting IC50 values of 0.192 μM for h-DHFR and 0.109 μM for EGFR. It causes cell cycle arrest at the G1/S phase and induces apoptosis. Additionally, EGFR/DHFR-IN-2 (9b) is a potential inhibitor of CYP2C9 and CYP3A4. This compound can be utilized in cancer research.Formule :C24H16N4O5Couleur et forme :SolidMasse moléculaire :440.11207icFSP1
CAS :icFSP1 is a mitochondria-associated apoptosis-inducing factor regulator with antitumor activity for the study and treatment of tumor diseases.Formule :C26H25N3O5Degré de pureté :99.87% - 99.93%Couleur et forme :SoildMasse moléculaire :459.49
