Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(154 produits)
- FOXO1(2 produits)
- IAP(67 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(140 produits)
- PDK(9 produits)
- PERK(24 produits)
- Sérine/thréonine kinase(19 produits)
- Survivant(14 produits)
- TNF(94 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6498 produits trouvés pour "Apoptose"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
F3-PEG8-RiboTAC
F3-PEG8-RiboTAC is a RiboTAC compound that specifically degrades the mRNA of the oncogene LGALS1. This compound can induce apoptosis (cell death) in tumor cells and inhibit their invasion. F3-PEG8-RiboTAC exhibits antitumor activity and is applicable in research on leukemia and triple-negative breast cancer. (RNase L ligand; RNA binder; Linker)Couleur et forme :Odour SolidThymocartin Acetate
CAS :Thymocartin Acetate, a thymopoietin fragment (32-35), inhibits enzyme breakdown; potential for immunodeficiency treatment.Formule :C23H44N8O9Couleur et forme :SoildMasse moléculaire :576.64MRIA9
CAS :MRIA9 inhibits SIK1/2/3 & PAK2/3 with IC50: SIK1 (516 nM), SIK2 (180 nM), SIK3 (127 nM); ATP-competitive.Formule :C24H22ClFN6O3Couleur et forme :SolidMasse moléculaire :496.92Bim BH3, Peptide IV
CAS :This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins.Formule :C145H222N44O41SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3269.65dASK1
CAS :dASK1 is a selective CRBN-based PROTAC degrader targeting apoptosis signal-regulating kinase 1 (ASK1). It forms a stable ternary complex with ASK1, facilitating its rapid and sustained degradation via the ubiquitin-proteasome pathway. dASK1 exhibits strong ASK1 degradation capabilities and is applicable for hepatitis research.Formule :C38H38F2N10O8Couleur et forme :SolidMasse moléculaire :800.77AY-4
AY-4 (Compound AY-4) is a potent PROTAC degrader targeting FTH1, with a dissociation constant (Kd) of 3.17 nM. It effectively increases intracellular ferrous (Fe2+) and ferric (Fe3+) ion levels. AY-4 is a potential anticancer candidate that regulates iron homeostasis through ferritin degradation, enhancing the efficacy of existing drugs. Additionally, AY-4 significantly reduces FTH1 levels in breast cancer cells.Couleur et forme :Odour SolidTrxR1-IN-2
TrxR1-IN-2 (Compound 6a) acts as a TrxR1 inhibitor that covalently bonds with the Cys475 and Sec498 sites of TrxR1. This interaction hampers TrxR1 activity, resulting in a redox homeostasis disruption and inducing apoptosis and ferroptosis.Formule :C19H23NO6Couleur et forme :SolidMasse moléculaire :361.389OBHSA
CAS :OBHSA（Oxabicycloheptane sulfonamide） is a novel selective estrogen receptor depressant (SERD) that can be used to study breast cancer.Formule :C27H24F3NO6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.54cis-Clovamide
CAS :cis-Clovamide is a naturally occurring phenolic compound with noteworthy antioxidant, anti-inflammatory, and antiapoptotic properties.Formule :C18H17NO7Couleur et forme :SolidMasse moléculaire :359.334(GalNAc)3-CPT
(GalNAc)3-CPT is a glycan-conjugated prodrug that targets the asialoglycoprotein receptor (ASGR) overexpressed on liver cells. It demonstrates significant antitumor activity by activating the cGAS-STING pathway and promoting CD8+ T cell infiltration into tumor sites, leading to apoptosis of tumor cells. In HepG2 cells, it shows an IC50 value of 3.07 μM.Couleur et forme :Odour SolidSodium fluoride
CAS :Sodium fluoride is a fluorinated inorganic salt. With wide range of applications. Sodium fluoride is used in trace amounts in the fluoridation of drinking water to prevent tooth decay, and in toothpastes and topical pharmaceuticals for the same purpose, it can also act as an insectcide, herbicide and fungicide.Formule :FnaCouleur et forme :SolidMasse moléculaire :41.99TRP-601
CAS :TRP-601 is a caspase inhibitor.Formule :C40H48F2N6O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :826.852Zaptuzumab
CAS :Zaptuzumab (AD5-10) is a humanized monoclonal antibody targeting death receptor 5 (DR5) with high selective binding affinity. It specifically induces cancer cell death through caspase-mediated apoptosis and autophagic cell death (ACD). Zaptuzumab can activate antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-dependent cytotoxicity (CDC). Additionally, it induces reactive oxygen species (ROS) production and reduces glutathione (GSH) levels. In various xenograft mouse tumor models, Zaptuzumab has demonstrated significant tumor growth inhibition and favorable safety profiles.Couleur et forme :LiquidLZ-07
LZ-07 is an IRAK4 PROTAC degrader (DC50 = 1.14 nM), that, upon degradation of IRAK4, significantly inhibits the expression of cytokines such as IL-6, IL-1β, TNF-α, and IL-10. It is applicable in research related to autoimmune diseases.Couleur et forme :Odour SolidDual Galectin-3/EGFR-IN-1
Dual Galectin-3/EGFR-IN-1 (Compound 29) is a dual inhibitor targeting Galectin-3 and EGFR, with dissociation constants (KD) of 52.29 μM and 3.31 μM, respectively. It inhibits TGF-β-induced hepatic stellate cell (HSC) activation, induces apoptosis in LX-2 cells, and shows antifibrotic activity in the liver.Formule :C32H41N7O10Couleur et forme :SolidMasse moléculaire :683.709Lactoferrin (17-41)
CAS :Amino acids 17-41 of lactoferrin, lactoferricin B, enhance anti-fungal effects, targeting Candida Albicans.Formule :C141H224N46O29S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3123.77STAT3-IN-40
CAS :STAT3-IN-40 (Compound 8b) is an anticancer agent. It initiates immune responses in CD4+ and CD8+ T lymphocytes by inhibiting the expression and phosphorylation of STAT3, and induces ferroptosis and apoptosis in tumor cells. STAT3-IN-40 is valuable for research into cancer chemoimmunotherapy drugs.Formule :C34H40ClN3O10PtCouleur et forme :SolidMasse moléculaire :881.232Varlilumab
CAS :Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.Degré de pureté :SDS-PAGE:95% SEC-HPLC:98.65%Couleur et forme :LiquidMasse moléculaire :146 kDaTubulysin B
CAS :Tubulysin B: a potent, cytotoxic microtubule-disrupting peptide from Archangium geophyra and Angiococcus disciformis.Formule :C42H63N5O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :830.04Targaprimir-96 TFA
Targaprimir-96 TFA is a selective inhibitor of miR-96 in cancer, inducing apoptosis with high affinity for pri-miR-96 but not affecting healthy cells.Formule :C79H103F3N18O9Couleur et forme :SolidMasse moléculaire :1505.77
