Apoptose
Les inhibiteurs de l'apoptose sont des composés qui empêchent ou retardent le processus de mort cellulaire programmée, connu sous le nom d'apoptose. Ces inhibiteurs sont essentiels pour étudier les mécanismes de survie cellulaire et sont utilisés pour enquêter sur les maladies où l'apoptose est dysrégulée, telles que le cancer, les troubles neurodégénératifs et les maladies auto-immunes. En modulant l'apoptose, ces inhibiteurs peuvent aider au développement de thérapies visant à contrôler la mort cellulaire. Chez CymitQuimica, nous offrons une sélection complète d'inhibiteurs de l'apoptose de haute qualité pour soutenir vos recherches en biologie cellulaire, oncologie et domaines connexes.
Sous-catégories appartenant à la catégorie "Apoptose"
- ASK(9 produits)
- BCL(1 produits)
- Caspase(155 produits)
- FOXO1(2 produits)
- IAP(68 produits)
- Mdm2(12 produits)
- PD-1/PD-L1(142 produits)
- PDK(9 produits)
- PERK(24 produits)
- Sérine/thréonine kinase(20 produits)
- Survivant(14 produits)
- TNF(95 produits)
- c-RET(61 produits)
- p53(63 produits)
Affichez 6 plus de sous-catégories
6499 produits trouvés pour "Apoptose"
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CDK-IN-14
CDK-IN-14 (B34) is a CDK2 inhibitor (IC50=0.097 μM) that exhibits anti-hepatocellular carcinoma activity. It inhibits the cell cycle in HepG-2 cancer cells and induces apoptosis (apoptosis) through a caspase-mediated mechanism.Couleur et forme :Odour SolidBetamethasone
CAS :Betamethasone (NSC-39470), a glucocorticoid steroid, has immunosuppressive and anti-inflammatory properties.Formule :C22H29FO5Degré de pureté :98% - 99.71%Couleur et forme :White Or Almost White Powder Solid CrystallineMasse moléculaire :392.46BWA-522
BWA-522 is a small molecule, orally available protein-targeting chimera (PROTAC) that potentates the degradation of both full-length androgen receptor (AR-FL)Formule :C43H51ClN4O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :771.34Anti-inflammatory agent 95
Anti-inflammatory agent 95 (Compound 2e) is a compound with potent anti-inflammatory properties, showing significant inhibition of NO production in LPS-induced RAW 264.7 mouse macrophages, with an IC50 of 8.8 μM. It also effectively suppresses the secretion of TNF-α and IL-1β, achieving inhibition rates of 60% and greater than 90% at 100 μM, respectively. Anti-inflammatory agent 95 holds promise for research into inflammatory diseases.Formule :C16H21NO4Couleur et forme :SolidMasse moléculaire :291.34Taccalonolide E
CAS :Taccalonolide E is a microtubule stabilizer and induces cancer cell apoptosis .Formule :C34H44O12Couleur et forme :SolidMasse moléculaire :644.71IPH10
IPH10 is an anticancer agent with strong antitumor effects in vivo and exhibits no liver or kidney toxicity. It significantly increases the reactive oxygen species (ROS) levels in tumor cells, decreases mitochondrial membrane potential, and induces apoptosis (apoptosis) in these cells.Formule :C32H33NO4Couleur et forme :SolidMasse moléculaire :495.61Multi-kinase-IN-4
Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.Formule :C21H20ClFN2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.91HEMTAC CDK4/6 degrader 1
CAS :HEMTAC CDK4/6 degrader 1, a PROTAC targeting HSP90/CDK4/6, Kd of 35.7 μM, disrupts B16F10 melanoma cell cycle, and induces apoptosis.Formule :C48H53ClN16O4Couleur et forme :SolidMasse moléculaire :953.49eIF4E-IN-6
eIF4E-IN-6 (Compound 4b), a GMP analog, is designed to inhibit the eIF4E protein's ability to bind to cap mRNA.Couleur et forme :Odour SolidAXL/Angiokinase-IN-1
AXL/Angiokinase-IN-1 (compound 11b) is an inhibitor of AXL/triple angiokinase, with an IC50 of 3.75 nM for AXL expression. This compound suppresses epithelial-mesenchymal transition (EMT) in Bxpc-3 cells and prevents metastasis in lung cancer cells. Additionally, AXL/Angiokinase-IN-1 impairs the functions of vascular and fibroblast cells and induces apoptosis in both cancer and fibroblast cells. It is characterized by low toxicity and favorable metabolic stability.Formule :C31H34ClN5O2Couleur et forme :SolidMasse moléculaire :544.09Pomalidomide-C5-Dovitinib
CAS :Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC that links Pomalidomide and Dovitinib via a CRBN connector, exhibiting potent antiproliferative activity inFormule :C39H38FN9O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :747.77Tubulin polymerization-IN-45
Tubulin polymerization-IN-45, a tubulin-targeting agent, acts as a tubulin polymerization inhibitor by binding to the tubulin's colchicine site.Formule :C20H18N4O3Couleur et forme :SolidMasse moléculaire :362.38Polyphyllin G
CAS :Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.Formule :C51H84O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1049.21Barasertib
CAS :AZD1152 is a pro-drug of Barasertib (AZD1152)-hQPA. Which is a highly selective Aurora B inhibitor with IC50 of 0.37 nM in a cell-free assay.Formule :C26H31FN7O6PDegré de pureté :99.92% - 99.97%Couleur et forme :SolidMasse moléculaire :587.54INF 195
CAS :INF 195 is an inflammasome NLRP3 inhibitor that can be used to study myocardial ischemia and myocardial infarction.Formule :C17H22ClNO3Degré de pureté :99.78%Couleur et forme :SoildMasse moléculaire :323.81Ferumoxytol
CAS :Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.Couleur et forme :SolidDestruxin B
CAS :Destruxin B: cyclic peptide from Metarhizium fungus, induces apoptosis in lung cancer via mitochondrial pathway.Formule :C30H51N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :593.766UZH1a
CAS :UZH1a: METTL3 inhibitor, IC50 280 nM, used for epitranscriptomic modulation and has antitumor properties.Formule :C32H42N6O3Couleur et forme :SoildMasse moléculaire :558.71Apoptosis inducer 3
CAS :Apoptosis Inducer 3 (Compound 3), a selective apoptosis triggering agent, induces both apoptosis and late-apoptosis phases, demonstrating cytotoxic effectsFormule :C49H55ClN2O7Couleur et forme :SolidMasse moléculaire :819.42Anticancer agent 52
CAS :Anticancer agent 52 exhibits potent cytotoxicity, induces apoptosis, and has potential in bladder cancer research.Formule :C50H43Br2N2PCouleur et forme :SolidMasse moléculaire :862.67
