Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(114 produits)
- CDK(545 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(47 produits)
- Dynamine(27 produits)
- Ferroptose(226 produits)
- HSP(179 produits)
- Intégrine(249 produits)
- Kinésine(87 produits)
- LIM Kinase(20 produits)
- Microtubules associés(274 produits)
- PKC(124 produits)
- PLK(25 produits)
- ROCK(62 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(76 produits)
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3859 produits trouvés pour "Cycle cellulaire/point de contrôle"
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NLS (PKKKRKV)
CAS :NLS (PKKKRKV) peptide from SV40 big T antigen boosts nuclear entry for gene transfer studies.Formule :C40H78N14O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :883.145'-ODMT cEt G Phosphoramidite (Amidite)
CAS :5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.Formule :C46H56N7O9PCouleur et forme :SolidMasse moléculaire :881.955'-O-DMT-rI
CAS :5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].Formule :C31H30N4O7Couleur et forme :SolidMasse moléculaire :570.59DNA Gyrase-IN-17
DNA Gyrase-IN-17 (Compound 5C) is an inhibitor of DNA gyrase. It demonstrates significant antimicrobial activity against a range of Gram-positive and Gram-negative strains, including Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa, with a MIC value of 62.5 μg/mL. By inhibiting bacterial DNA gyrase, DNA Gyrase-IN-17 disrupts DNA replication. This compound can be useful in the development of antibiotics, particularly for studying resistant strains.Formule :C18H15ClFN5OCouleur et forme :SolidMasse moléculaire :371.09492HSDVHK-NH2
CAS :Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.Formule :C30H48N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :720.7813-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.235'-O-DMT-PAC-dA
CAS :5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].Formule :C39H37N5O7Couleur et forme :SolidMasse moléculaire :687.743'-Deoxyuridine-5'-triphosphate trisodium
3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).Formule :C9H12N2Na3O14P3Couleur et forme :SoildMasse moléculaire :534.08Dihydro-5-azacytidine
CAS :Dihydro-5-azacytidine (DHAC) is a nucleoside analog that interrupts DNA methylation by integrating into DNA. It also exhibits notable antitumor properties.Formule :C8H14N4O5Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :246.22Risuteganib
CAS :Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.
Formule :C22H39N9O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :637.665-Caroxy uracil-1-yl acetic acid benzyl ester
5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.Formule :C14H12N2O6Couleur et forme :SolidMasse moléculaire :304.25Rev 2'-O-MOE-C(Bz)-5'-amidite
'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.Formule :C49H58N5O10PCouleur et forme :SolidMasse moléculaire :907.99αvβ5 integrin-IN-1
CAS :αvβ5 integrin-IN-1, a potent and selective αvβ5 integrin inhibitor, exhibits a high inhibitory potency with a pIC50 value of 8.2.Formule :C25H28F3N3O3Couleur et forme :SolidMasse moléculaire :475.5126-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine, a purine nucleoside analogue, exhibits broad antitumor activity byFormule :C15H17N5O6Couleur et forme :SolidMasse moléculaire :363.333'Ome-m7GpppAmpG
CAS :3'Ome-m7GpppAmpG is a trinucleotide cap with LNA, boosting translation; useful in mRNA vaccines and gene therapy.Formule :C33H45N15O24P4Couleur et forme :SolidMasse moléculaire :1159.695'-O-TBDMS-dU
CAS :5'-O-TBDMS-dU can be used in the synthesis of oligoribonucleotides.Formule :C15H26N2O5SiCouleur et forme :SolidMasse moléculaire :342.467LDV FITC
CAS :fluorescent ligand that binds to the α4β1 integrin (VLA-4)Formule :C69H81N11O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1368.53Thailanstatin C
CAS :Thailanstatin C from Burkholderia thailandensis blocks pre-mRNA splicing, IC50 6.84 μM.Formule :C30H46ClNO9Couleur et forme :SolidMasse moléculaire :600.15PROTAC CDK9 degrader-5
CAS :PROTAC CDK9 degrader-5 selectively degrades CDK9 isoforms 42, 55 with DC50 of 0.10μM, 0.14μM via proteasome.Formule :C42H48Cl2N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :879.78CDK2-IN-43
CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. It is applicable to cancer research.Formule :C19H27N7OCouleur et forme :SolidMasse moléculaire :369.4645'-O-TBDMS-Bz-dA
CAS :5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.Formule :C23H31N5O4SiCouleur et forme :SolidMasse moléculaire :469.617ROCK-IN-32
CAS :ROCK-IN-32 is an effective Rho-kinase inhibitor.Formule :C20H17Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.27N1-Benzoyl pseudouridine
N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.Formule :C16H16N2O7Couleur et forme :SolidMasse moléculaire :348.31LY2812223
CAS :LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).Formule :C10H12N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :284.29dUTP trisodium
CAS :dUTP trisodium (Deoxyuridine triphosphate) is a deoxyuridine phosphate having a triphosphate group at the 5'-position and can be used for PCR.
Formule :C9H12N2Na3O14P3Degré de pureté :100.00%Couleur et forme :SolidMasse moléculaire :534.09CPS2
CAS :CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.Formule :C38H42N12O10S2Couleur et forme :SolidMasse moléculaire :890.942'-Deoxy-2'-fluoro-N3-(n-dodecyl)uridine
2’-Deoxy-2’-fluoro-N3-(n-dodecyl)uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C21H35FN2O5Couleur et forme :SolidMasse moléculaire :414.51Emofolin sodium
CAS :Emofolin sodium, a synthetic folate analogue, inhibits DNA/RNA/protein synthesis by blocking dihydrofolate reductase.Formule :C21H25N7Na2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :517.45Deoxythymidine-5'-triphosphate
CAS :Deoxythymidine-5'-triphosphate (dTTP) is a nucleoside triphosphate involved in DNA synthesis.Formule :C10H17N2O14P3Couleur et forme :SolidMasse moléculaire :482.167Aclacinomycin A
CAS :Aclacinomycin A has a wide range of applications in life science related research.Formule :C42H53NO15Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :811.87AV-153
CAS :AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.Formule :C14H19NNaO6Couleur et forme :SolidMasse moléculaire :320.297Cy5-dATP
Cy5-dATP is a Cy5 -labeled dATP . Cy5-dATP can be incorporated into a DNA primer [1] [2] .
Formule :C47H58N7O19P3S2Couleur et forme :SolidMasse moléculaire :1182.05CDK8-IN-12
CAS :CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.Formule :C21H20ClN3O2Degré de pureté :98.55% - 99.22%Couleur et forme :SoildMasse moléculaire :381.86Ref: TM-T72048
1mg52,00€5mg101,00€10mg150,00€25mg250,00€50mg363,00€100mg509,00€200mg695,00€1mL*10mM (DMSO)116,00€AR-13324 analog mesylate
AR-13324 analog mesylate is an inhibitor of Rho-kinase and a norepinephrine transporter and reduces intraocular pressure in normotensive monkey eyes.Formule :C29H33N3O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :631.72TMX-2138
CAS :TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.Formule :C40H43BrFN9O11SCouleur et forme :SolidMasse moléculaire :956.791PROTAC CDK9 degrader-2
CAS :PROTAC CDK9 degrader-2, potent, selective, IC50 17 μM in MCF-7, wogonin-derived, targets CRBN.Formule :C39H36N6O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :748.74DHODH-IN-16
CAS :DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).Formule :C24H25FN4O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :436.48N1-(2-Methyl)propyl pseudouridine
N1-(2-Methyl)propyl pseudouridine, a purine analog, targets lymphoid cancer by inhibiting DNA synthesis and inducing apoptosis.Formule :C13H20N2O6Couleur et forme :SolidMasse moléculaire :300.313,6-DMAD hydrochloride
3,6-DMAD hydrochloride functions as an inhibitor for the IRE1α-XBP1 pathway within the unfolded protein response mechanism.Formule :C22H31N5xHClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.52Antibacterial agent 144
Antibacterial Agent 144 (compound 8e) exhibits superior efficacy against multi-resistant Staphylococcus aureus compared to Chloromycin and Amoxicillin.Formule :C26H23N7O3Couleur et forme :SolidMasse moléculaire :481.51Tirandamycin A
Tirandamycin A is a useful organic compound for research related to life sciences and the catalog number is T124996.Formule :C22H27NO7Couleur et forme :SolidMasse moléculaire :417.458EC0489
CAS :EC0489, Small molecule-drug conjugate (SMDC) ,a conjugate of folic acid and desacetyl vinblastine hydrazide, is a high-affinity ligand for the folate receptor (Formule :C111H156N22O43S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2550.7Rachelmycin
CAS :Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.Formule :C37H33N7O8Couleur et forme :SolidMasse moléculaire :703.71211H-Benzo[a]carbazole
CAS :11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.Formule :C16H11NDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :217.2712R-LOX-IN-2
CAS :12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.Formule :C19H13NODegré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :271.31Anti-EMMPRIN/CD147 Antibody
Anti-EMMPRIN/CD147 Antibody is a human-derived antibody expressed in CHO cells, targeting Basigin. For an isotype control, refer to HumanIgG1kappa, Isotype Control.Couleur et forme :Odour LiquidDSPE-PEG2000-cRGD
DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.Couleur et forme :Odour SolidIBU-DC Phosphoramidite
CAS :IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.Formule :C43H54N5O8PCouleur et forme :SolidMasse moléculaire :799.906DG1
DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressingFormule :C19H17N5O5SCouleur et forme :SolidMasse moléculaire :427.43CDK7-IN-5
CAS :CDK7-IN-5, a CDK7 inhibitor with an IC 50 value of less than 100 nM, exhibits potent anticancer properties (WO2015154022A1, Compound 104).Formule :C34H45N9O2Couleur et forme :SolidMasse moléculaire :611.795SP27
CAS :SP27, a selective PROTAC, degrades PLK4 with a DC50 of 19.5 nM and may be utilized in breast cancer research [1].Formule :C40H40F2N12O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :806.82Fibronectin CS1 Peptide
CAS :Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.Formule :C38H64N8O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.96Cdk2/Cyclin Inhibitory Peptide I
CDK2, a Ser/Thr kinase, is akin to yeast cdc28 and human Cdk1, crucial for cell division.Formule :C111H196N48O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2571.055'-O-TBDMS-dG
CAS :5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.Formule :C16H27N5O4SiCouleur et forme :SolidMasse moléculaire :381.50CD532 hydrochloride
CD532 hydrochloride, potent Aurora A inhibitor (IC50=45 nM), hampers MYCN protein, changes AURKA's shape, aids cancer research.Couleur et forme :SolidKIF2C-IN-1
KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.Formule :C36H39ClN4O9SCouleur et forme :SolidMasse moléculaire :738.21263Chrexanthomycin C
Chrexanthomycin C, orally active, binds DNA (G4C2)4 G4, Kd 2.8 mM, potential in ALS research.Formule :C31H24O15Couleur et forme :SolidMasse moléculaire :636.51N6-Methyl-2'-O-(2-methoxyethyl) adenosine
N6-Methyl-2’-O-(2-methoxyethyl) adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H21N5O5Couleur et forme :SolidMasse moléculaire :339.35Pyrindamycin A
CAS :Pyrindamycin A is an antibiotic that inhibits DNA synthesis,and shows antitumor activities against murine leukemia.Formule :C26H26ClN3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :543.95[pSer2, pSer5, pSer7]-CTD TFA
Substrate '[pSer2, pSer5, pSer7]-CTD (TFA)' for CDK7 phosphorylates RNA Pol II CTD at ser2, 5, 7.Formule :C98H138F3N21O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2291.25PROTAC CDK9 degrader-7
CAS :PROTAC CDK9 degrader-7 is a proteolysis-targeting chimera (PROTAC) specifically designed to target and mediate the degradation of Cyclin-Dependent Kinase 9 (Formule :C43H50Cl2N8O9Couleur et forme :SoildMasse moléculaire :893.81BAY-728
BAY-728 serves as a negative control for BAY-805, a potent and selective inhibitor of USP21 [1].Formule :C24H28F3N5O2SCouleur et forme :SolidMasse moléculaire :507.57MYC-IN-2
CAS :MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.Formule :C25H17N3O2SCouleur et forme :SolidMasse moléculaire :423.49CDK2/PIM1-IN-1
CDK2/PIM1-IN-1 is an inhibitor of the kinases CDK2 (IC50: 0.27 μM) and PIM1 (IC50: 0.67 μM). It can induce apoptosis (cell death) and reduce the expression of TNF-α, which promotes tumors. CDK2/PIM1-IN-1 exhibits antitumor activity.
Couleur et forme :Odour SolidPAT-LM1
PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.Couleur et forme :Odour LiquidDSPE-PEG1000-iRGD
DSPE-PEG1000-iRGD is a PEG compound made from DSPE and the αv-integrin-targeting peptide (iRGD). The iRGD peptide initially binds to αv-integrins and undergoes proteolytic cleavage within tumors to produce CRGDK/R, which interacts with neuropilin-1, thereby facilitating tumor targeting and penetration. DSPE-PEG1000-iRGD is useful for drug delivery applications.Couleur et forme :Odour SolidBLINK15
BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.Couleur et forme :Odour SolidFlurocitabine HCl
CAS :Fluorocitabine HCl, a cytarabine analog, hydrolyzes into ara-FC and ara-FU, showing antitumor effects in leukemia and solid cancers.Formule :C9H11ClFN3O4Degré de pureté :99.23% - 99.76%Couleur et forme :SoildMasse moléculaire :279.65MRK-952
MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.Formule :C20H20ClF3N6Couleur et forme :SolidMasse moléculaire :436.861THK01
CAS :THK01: ROCK2 inhibitor (IC50=5.7nM), less effective on ROCK1 (923nM). Hinders breast cancer spread via ROCK2-STAT3. For cancer research.Formule :C20H13N3O2Couleur et forme :SolidMasse moléculaire :327.34DHFR-IN-8
DHFR-IN-8 (compound 6r), a dihydrofolate reductase (DHFR) inhibitor, disrupts purine and thymidylate biosynthesis critical for cell proliferation and growth.Formule :C18H14N6SCouleur et forme :SolidMasse moléculaire :346.413'-β-C-Methyl-2-thiouridine
3’-β-C-Methyl-2-thiouridine, a purine nucleoside analog, exhibits extensive antitumor activity, particularly against indolent lymphoid malignancies.Formule :C10H14N2O5SCouleur et forme :SolidMasse moléculaire :274.29CDK5-IN-1
CAS :CDK5-IN-1: Potent CDK5 inhibitor (<10 nM) used in kidney disease research.Formule :C24H25FN6O3SCouleur et forme :SolidMasse moléculaire :496.56DSPE-PEG5000-cRGD
DSPE-PEG5000-cRGD is a PEG compound composed of DSPE and an αvβ3 targeting peptide (cRGD). The cRGD peptide has the ability to specifically bind to the αvβ3 present on the surfaces of numerous cancer cells and new vascular cells. DSPE-PEG5000-cRGD is useful for drug delivery applications.Couleur et forme :Odour Solid5'-O-DMT-N2-DMF-dG
CAS :5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.Formule :C34H36N6O6Couleur et forme :SolidMasse moléculaire :624.698GRGDSP
CAS :Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.Formule :C22H37N9O10Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :587.58dAURK-4
CAS :dAURK-4, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].Formule :C52H52ClFN8O12Couleur et forme :SolidMasse moléculaire :1035.47K34c hydrochloride
CAS :K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.Formule :C26H30ClN3O4Degré de pureté :99.76% - 99.89%Couleur et forme :SoildMasse moléculaire :483.99HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.49Isocytosine
CAS :Compound PDK0016, with CAS No. 108-53-2, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0016 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.Formule :C4H5N3OCouleur et forme :White To Off-White SolidMasse moléculaire :111.17-TFA-ap-7-Deaza-ddA
CAS :Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.Formule :C16H16F3N5O3Couleur et forme :SolidMasse moléculaire :383.331ROCK-IN-5
CAS :ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.Formule :C16H11ClFN3OSDegré de pureté :99.72% - 99.86%Couleur et forme :SolidMasse moléculaire :347.795-Methylcytidine 5′-triphosphate trisodium
5-Methylcytidine 5′-triphosphate trisodium (5-Methyl-CTP trisodium), a modified nucleoside triphosphate, enhances translational properties and stability, while
Formule :C10H15N3Na3O14P3Couleur et forme :SolidMasse moléculaire :563.13N1-Methylpseudouridine-5′-triphosphate tetralithium
N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.Formule :C10H13Li4N2O15P3Couleur et forme :SolidMasse moléculaire :521.9N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.Formule :C14H22N2O7Couleur et forme :SolidMasse moléculaire :330.33Stigmatellin
CAS :Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.Formule :C30H42O7Couleur et forme :SolidMasse moléculaire :514.655'-O-TBDMS-N2-ibu-dG
CAS :5'-O-TBDMS-N2-ibu-dG: a nucleoside derivative with strong anti-BVDV activity, useful in lead compound synthesis.Formule :C20H33N5O5SiCouleur et forme :SolidMasse moléculaire :451.592'-Chloro-N6-(3-trifluoromethyl)benzyl adenosine
2’-Chloro-N6-(3-trifluoromethyl)benzyl adenosine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoidFormule :C18H17ClF3N5O4Couleur et forme :SolidMasse moléculaire :459.81LDV
CAS :α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.Formule :C48H70N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :979.13Biotin-PEG7-C2-NH-Vidarabine-S-CH3
Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG linker with Vidarabine, an anti-herpes/zoster antiviral.Formule :C37H62N8O12S2Couleur et forme :SolidMasse moléculaire :875.06Remdesivir nucleoside monophosphate
CAS :Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.Formule :C12H14N5O7PCouleur et forme :SolidMasse moléculaire :371.24N1-Methylxylo-guanosine
N1-Methylxylo-guanosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Formule :C11H15N5O5Couleur et forme :SolidMasse moléculaire :297.27Pseudouridimycin
CAS :Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.Formule :C17H26N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.44Eesperamicin A1
CAS :Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.Formule :C59H80N4O22S4Couleur et forme :SolidMasse moléculaire :1325.54PKMYT1-IN-3
PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 nM and exhibiting antitumor activity.Formule :C24H26FN5O2Couleur et forme :SolidMasse moléculaire :435.492'-Deoxy-2'-fluoro-l-uridine
CAS :2'-Deoxy-2'-fluoro-1-uridine: an L-nucleoside, inhibits RNA viruses by blocking viral RNA polymerase.Formule :C9H11FN2O5Couleur et forme :SolidMasse moléculaire :246.19DSPE-PEG2000-iRGD
DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.Couleur et forme :Odour SolidPhen-DC3 Trifluoromethanesulfonate
CAS :Phen-DC3 Trifluoromethanesulfonate targets G-quadruplexes and inhibits FANCJ/DinG helicases; IC50s: 65±6/50±10 nM.Formule :C36H26F6N6O8S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :848.75AURKA against 1
Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.Formule :C28H32FN9O2Couleur et forme :SolidMasse moléculaire :545.614-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS :4-Amino-5-cyano-1-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy,Formule :C13H15N5O4Couleur et forme :SolidMasse moléculaire :305.29
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