Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(114 produits)
- CDK(546 produits)
- Arrêt du cycle cellulaire(5 produits)
- Chk(48 produits)
- DYRK(47 produits)
- Dynamine(27 produits)
- Ferroptose(226 produits)
- HSP(179 produits)
- Intégrine(251 produits)
- Kinésine(87 produits)
- LIM Kinase(20 produits)
- Microtubules associés(274 produits)
- PKC(124 produits)
- PLK(25 produits)
- ROCK(62 produits)
- Rho(6 produits)
- Wee1(14 produits)
- c-Myc(76 produits)
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3870 produits trouvés pour "Cycle cellulaire/point de contrôle"
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AB-3PRGD2
CAS :AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.
Formule :C137H215IN30O45SCouleur et forme :SolidMasse moléculaire :3161.32TLR7 agonist 12
CAS :TLR7 agonist 12, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Formule :C14H19N5O8Couleur et forme :SolidMasse moléculaire :385.33Rifalazil
CAS :Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.Formule :C51H64N4O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :941.07Garenoxacin
CAS :Garenoxacin (BMS284756) is a novel oral des-fluoro(6) quinolone for the treatment of Gram-positive and Gram-negative bacterial infections.Formule :C23H20F2N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :426.41Chk1-IN-6
CAS :Chk1-IN-6 is a potent, selective, and orally bioavailable CHK1 inhibitor candidate.
Formule :C16H18F3N7Couleur et forme :SolidMasse moléculaire :365.364Uridine-5-(N-Fmoc-methylamino)-acetyl (9-fluorenylmethyl) ester
Uridine derivative with antitumor properties blocks DNA synthesis and induces apoptosis in lymphoid cancers.Formule :C41H37N3O10Couleur et forme :SolidMasse moléculaire :731.75αVβ8-IN-1
CAS :αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.015'-ODMT cEt G Phosphoramidite (Amidite)
CAS :5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.Formule :C46H56N7O9PCouleur et forme :SolidMasse moléculaire :881.95Rev dC(Bz)-5'-amidite
Rev dC(Bz)-5'-amidite, a purine nucleoside analog with antitumor effects, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.Formule :C46H52N5O8PCouleur et forme :SolidMasse moléculaire :833.91Ac-MRGDH-NH2
Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.Formule :C25H41N11O8SCouleur et forme :SolidMasse moléculaire :655.727Sarecycline hydrochloride
CAS :Sarecycline hydrochloride is a narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity.Formule :C24H30ClN3O8Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :523.96Confidential-2
Confidential-2: a purine nucleoside analog with antitumor effects on lymphoid cancers, inhibits DNA synthesis, induces apoptosis.Formule :C20H25N5O8Couleur et forme :SolidMasse moléculaire :463.44PLK1-IN-14
PLK1-IN-14 (Compound Hit-4) is a selective PLK1 inhibitor with an IC50 of 22.61 pM for PLK1, and an IC50 of 0.09 nM for inhibiting the proliferation of DU-145 prostate cancer cells. It is applicable in prostate cancer research.Couleur et forme :Odour SolidEFdA-TP
CAS :EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.Formule :C12H15FN5O12P3Couleur et forme :SolidMasse moléculaire :533.195LB80317
CAS :LB-80317, a DNA polymerase inhibitor, is used potentially for the potential treatment of hepatitis B virus infection.Formule :C10H14N5O5PCouleur et forme :SolidMasse moléculaire :315.222'-β-C-Methyl-3-deazauri dine
CAS :2’-β-C-Methyl-3-deazauridine, a purine nucleoside analogue, exhibits wide antitumor activity specifically against indolent lymphoid malignancies.Formule :C11H15NO6Couleur et forme :SolidMasse moléculaire :257.24Heliquinomycin
CAS :Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.Formule :C33H30O17Couleur et forme :SolidMasse moléculaire :698.5865'-O-Benzoyl-3'-O-(4-methoxybenzyl)-2'-O,4'-C-methyleneuridine
5’-O-Benzoyl-3’-O-(4-methoxybenzyl)-2’-O,4’-C-methyleneuridine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolentFormule :C25H24N2O8Couleur et forme :SolidMasse moléculaire :480.47N1-Methyl-2'-β-C-methyl inosine
N1-Methyl-2’-beta-C-methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies through mechanisms thatFormule :C12H16N4O5Couleur et forme :SolidMasse moléculaire :296.28N4-(3,3,3-Trifluoropropanoyl)cytidine
N4-(3,3,3-Trifluoropropanoyl)cytidine, a cytidine analog, inhibits DNA methyltransferases, possibly anti-metabolic and anti-cancer.Formule :C12H14F3N3O6Couleur et forme :SolidMasse moléculaire :353.25T-2513
CAS :T-2513 inhibits topoisomerase I by covalently bonding to its DNA complex, blocking DNA replication and causing cell death.Formule :C25H27N3O5Couleur et forme :SolidMasse moléculaire :449.5072-Diethoxymethyl adenosine
2-Diethoxymethyl adenosine, an adenosine analog, dilates smooth muscle, inhibits cancer, and leads to drugs like Acadesine.Formule :C23H31N5O10Couleur et forme :SolidMasse moléculaire :537.523'-β-C-ethynyl-N6-iso-pentenyl adenosine
3’-Beta-C-ethynyl-N6-iso-pentenyl adenosine is an adenosine analog.Formule :C17H21N5O4Couleur et forme :SolidMasse moléculaire :359.38Eesperamicin A1
CAS :Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.Formule :C59H80N4O22S4Couleur et forme :SolidMasse moléculaire :1325.54Chrysomycin A
CAS :Chrysomycin A is an antibiotic that can be derived from Streptomyces.Formule :C28H28O9Couleur et forme :SolidMasse moléculaire :508.522'-O-Methyladenosine 5'-monophosphate triethyl ammonium
2’-O-Methyladenosine 5’-monophosphate triethyl ammonium is an adenosine analog.Formule :C11H14N5O7P2Couleur et forme :SolidMasse moléculaire :359.23Rachelmycin
CAS :Rachelmycin, a potent antibiotic and antitumor agent from Streptomyces zelensis, binds to DNA's minor groove.Formule :C37H33N7O8Couleur et forme :SolidMasse moléculaire :703.712Nogalamycin
CAS :Nogalamycin is an anthracycline antibiotic with antitumor properties produced by soil bacteria Streptomyces nogalater.Formule :C39H49NO16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :787.812CDK7-IN-2 hydrochloride hydrate
CAS :CDK7-IN-2 HCl hydrate is a potent, specific CDK7 enzyme inhibitor with significant anti-cancer effects.Formule :C26H42ClN7O4Couleur et forme :SolidMasse moléculaire :552.125'-O-DMTr-2'-O-MOE inosine 3'-P-methyl phosphonamidite
5’-O-DMTr-2’-O-MOE inosine 3’-P-methyl phosphonamidite, a purine nucleoside analog, exhibits extensive antitumor activity specific to indolent lymphoidFormule :C41H52N5O8PCouleur et forme :SolidMasse moléculaire :773.85THK01
CAS :THK01: ROCK2 inhibitor (IC50=5.7nM), less effective on ROCK1 (923nM). Hinders breast cancer spread via ROCK2-STAT3. For cancer research.Formule :C20H13N3O2Couleur et forme :SolidMasse moléculaire :327.34XT17
XT17 is an anthrone compound with broad-spectrum antibacterial activity, exerting its effects by disrupting the cell wall and inhibiting DNA synthesis. It demonstrates weak hemolytic activity, low cytotoxicity to mammalian cell lines, and a low rate of resistance development. Additionally, XT17 shows in vivo efficacy in a mouse corneal infection model induced by Staphylococcus aureus or Pseudomonas aeruginosa. Further docking studies confirm that XT17 forms a stable complex with bacterial gyrase. XT17 is suitable for research in the field of anti-infective agents.Couleur et forme :Odour SolidJB300
CAS :JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.Formule :C43H45ClFN7O10SCouleur et forme :SolidMasse moléculaire :906.3758-Chloro-2'-deoxy-2'-fluoro-arabino adenosine
8-Chloro-2’-deoxy-2’-fluoro-arabino adenosine, a purine nucleoside analog, demonstrates broad antitumor activity against indolent lymphoid malignancies.Formule :C10H11ClFN5O3Couleur et forme :SolidMasse moléculaire :303.68PLK1-IN-12
PLK1-IN-12 is a highly selective, orally active PLK1 inhibitor with an IC50 of 20 nM. It demonstrates greater selectivity for PLK1 over PLK2 (IC50: >10000 nM) and PLK3 (IC50: 3953 nM). PLK1-IN-12 exhibits anticancer efficacy across a wide range of cell lines and is applicable to anti-leukemia research.Couleur et forme :Odour Solid2-(3-Methyln-propylidene hydrazino) adenosine
2-(3-Methyln-propylidene hydrazino) adenosine: a purine analog with antitumor properties, inhibits DNA synthesis, induces apoptosis.Formule :C15H23N7O4Couleur et forme :SolidMasse moléculaire :365.395'-O-TBDMS-dA
CAS :5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.
Formule :C16H27N5O3SiCouleur et forme :SolidMasse moléculaire :365.509Lorutengitide
CAS :Lorutengitide is a transcription-regulating peptide with antiproliferative activity.Formule :C30H50N8O12Couleur et forme :SolidMasse moléculaire :714.764WAY-647802
CAS :WAY-647802 is a CDK inhibitor.Formule :C11H14N4O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :250.25N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine
N3-(2S)-propyluridine is a uridine analog with potential as an antiepileptic and for antihypertensive agent research.Formule :C22H35N3O10Couleur et forme :SolidMasse moléculaire :501.53Anticancer agent 263
Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.Formule :C13H20N2O6Couleur et forme :SolidMasse moléculaire :300.308Mumefural
CAS :Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.
Formule :C12H12O9Couleur et forme :SolidMasse moléculaire :300.22JH-XVI-178
CAS :JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.Formule :C22H22ClN7OCouleur et forme :SolidMasse moléculaire :435.92Cytidine 5'-diphosphate trisodium salt
CAS :CDP, a trisodium salt, helps synthesize DNA/RNA by aiding phosphoryl transfer from ATP to CMP via UMPK.Formule :C9H15N3Na3O11P2Degré de pureté :99.55%Couleur et forme :White Crystalline PowderMasse moléculaire :472.15IBU-DC Phosphoramidite
CAS :IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.Formule :C43H54N5O8PCouleur et forme :SolidMasse moléculaire :799.9065'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl) inosine
5’-O-(4,4’-Dimethoxytrityl)-2’-O-(2-methoxyethyl)inosine is a purine nucleoside analog with broad antitumor activity, primarily targeting indolent lymphoidFormule :C34H36N4O8Couleur et forme :SolidMasse moléculaire :628.67CDK2-IN-43
CDK2-IN-43 (Compound 3a) is a CDK2-cyclin E2 inhibitor with an IC50 value of 6.0 nM. It is applicable to cancer research.Formule :C19H27N7OCouleur et forme :SolidMasse moléculaire :369.464N1-Methylxylo-guanosine
N1-Methylxylo-guanosine, a purine analog, targets lymphoid cancer via DNA synthesis inhibition and apoptosis.Formule :C11H15N5O5Couleur et forme :SolidMasse moléculaire :297.275-Iminodaunorubicin
CAS :5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.Formule :C27H30N2O9Couleur et forme :SolidMasse moléculaire :526.542'-Deoxy-2'-fluorouridine 5'-monophosphate triethyl ammonium
2’-Deoxy-2’-fluorouridine 5’-monophosphate triethyl ammonium, a purine nucleoside analog, exhibits extensive antitumor effects against indolent lymphoidFormule :C21H42FN4O7PCouleur et forme :SolidMasse moléculaire :512.553'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
3’-O-DMT-N2-isobutyryl-2’-O-(2-methoxyethyl)guanosine, a purine nucleoside analog, exhibits broad antitumor activity particularly against indolent lymphoidFormule :C38H43N5O9Couleur et forme :SolidMasse moléculaire :713.785'-O-DMT-N4-Ac-2'-F-dC
CAS :5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.Formule :C32H32FN3O7Couleur et forme :SolidMasse moléculaire :589.615'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.Formule :C44H49F2N4O7PCouleur et forme :SolidMasse moléculaire :814.85α2β1 Integrin Ligand Peptide TFA
α2β1 Integrin Ligand Peptide TFA interacts with the integrin receptor on the cell membrane and enters the cell to mediate extracellular signaling.It is aFormule :C16H23F3N4O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.37HDAC-IN-85
HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.49Brr2-IN-2
Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.Formule :C21H25FN4O2Couleur et forme :SolidMasse moléculaire :384.45Apcin A HCL
CAS :Apcin A HCL is an Apcin-derived APC inhibitor that binds Cdc20 and hinders ubiquitination, useful for synthesizing PROTAC CP5V.
Formule :C10H15Cl4N5O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :379.07[pThr3]-CDK5 Substrate
CAS :[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate.[pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1].Formule :C53H100N15O15PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1218.4313-TP
13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23(1S,3R,5R)-PIM447 dihydrochloride
(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).Formule :C24H25Cl2F3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.38CDK7-IN-21
CAS :CDK7-IN-21 (compound A22) is a potent CDK7 inhibitor [1] .Formule :C33H36FN9O2Couleur et forme :SolidMasse moléculaire :609.7Trimethoprim hydrochloride
CAS :Trimethoprim hydrochloride: oral, broad-spectrum antibiotic, DHFR inhibitor, treats UTIs, shigellosis, pneumocystis pneumonia, may block Influenza A with zinc.Formule :C14H19ClN4O3Couleur et forme :SolidMasse moléculaire :326.78Obtustatin
Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.Formule :C184H284N52O57S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4393.07CDK4/6-IN-5
CAS :CDK4/6-IN-5 inhibits CDK4/6; Ki: 0.2 nM (CDK4/D1) & 4.4 nM (CDK6/D3). (WO2019207463A1, A93)Formule :C22H28ClFN6O4SCouleur et forme :SolidMasse moléculaire :527.01Gly-Arg-Gly-Asp-Ser
CAS :Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.Formule :C17H30N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.47Solidagonic acid
CAS :Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.Formule :C22H34O4Couleur et forme :SolidMasse moléculaire :362.5Rev 2'-O-MOE-A(Bz)-5'-amidite
'Rev 2’-O-MOE-A(Bz)-5’-amidite is a nucleoside analog specifically categorized within the purine subset, renowned for its wide-ranging antitumor efficacyFormule :C50H58N7O9PCouleur et forme :SolidMasse moléculaire :932.01MS7131
MS7131 is a DUBTAC inhibitor that recruits USP1. It effectively reduces histone H3 lysine 27 trimethylation and significantly inhibits the proliferation and colony-forming ability of cancer cells.Couleur et forme :Odour SolidMYC-IN-2
CAS :MYC-IN-2 is a protein-protein inhibitor targeting the MYC protein, designed for use in cancer research.Formule :C25H17N3O2SCouleur et forme :SolidMasse moléculaire :423.49Pseudorabies virus-IN-1
Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.Formule :C27H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :508.947ONX 0801 trisodium
CAS :ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.Formule :C32H30N5Na3O10Couleur et forme :SolidMasse moléculaire :713.58DHFR-IN-11
DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.Couleur et forme :Odour Solid5'-O-TBDMS-Bz-dA
CAS :5’-O-TBDMS-Bz-dA is a nucleoside with protective and modification effects.Formule :C23H31N5O4SiCouleur et forme :SolidMasse moléculaire :469.617BIO5192 hydrate
BIO5192 hydrate: potent α4β1 inhibitor, binds selectively (Kd<10 pM, IC50=1.8 nM), boosts murine HSPC mobilization 30x.Couleur et forme :SolidN4-(n-Palmitoyl)-4'-azido-2'-deoxy-2'-fluoro-arabinocytidine
N4-(n-Palmitoyl)-4’-azido-2’-deoxy-2’-fluoro-arabinocytidine is a cytidine nucleoside analog.Formule :C25H41FN6O5Couleur et forme :SolidMasse moléculaire :524.63WAY-322243
CAS :WAY-322243 has antibacterial and anti-inflammatory activity and has an inhibitory effect on CLK-1, which can be used to study Alzheimer's disease.Formule :C18H18N2O2SDegré de pureté :99.88%Couleur et forme :SoildMasse moléculaire :326.41Ganodermaones B
Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.433'-β-C-ethynyl-N6-(m-trifluoromethyl benzyl)adenosine
3’-Beta-C-ethynyl-N6-(m-trifluoromethyl benzyl)adenosine is an adenosine analog.Formule :C20H18F3N5O4Couleur et forme :SolidMasse moléculaire :449.38L-5-Methyluridine
CAS :L-5-Methyluridine, an L-configuration of 5-Methyluridine, is an endogenous methylated nucleoside present in human fluids.Formule :C10H14N2O6Couleur et forme :SolidMasse moléculaire :258.23S-MGB-234
CAS :S-MGB-234 treats AAT, effective against T. congolense and T. vivax, no cross-resistance or shared transport with diamidines.Formule :C30H32N8O4Couleur et forme :SolidMasse moléculaire :568.638EFdA-TP tetraammonium
EFdA-TP tetraammonium is a potent HIV-1 RT inhibitor and DNA synthesis blocker, acting as an ICT or DCT.Formule :C12H27N9O12P3Couleur et forme :SolidMasse moléculaire :601.31Evybactin
Evybactin: a selective DNA gyrase inhibitor for Mycobacterium tuberculosis (MIC 0.25 µg/mL), first of its kind.Formule :C64H89N21O21Couleur et forme :SolidMasse moléculaire :1488.52DSPE-PEG2000-iRGD
DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.Couleur et forme :Odour SolidFF-10502
CAS :FF-10502, a pyrimidine analog of Gemcitabine, inhibits DNA polymerases α/β, targeting dormant cancer cells.Formule :C9H12FN3O3SCouleur et forme :SolidMasse moléculaire :261.27N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS :N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].
Formule :C21H35N12O17P3Couleur et forme :SolidMasse moléculaire :820.49STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Degré de pureté :97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :Odour LiquidRNA splicing modulator 1
CAS :RNA Splicing Modulator 1 (Compound 233) is a modulator of RNA splicing, exhibiting an AC50 value of less than 100 nM [1].
Formule :C19H20N6OSCouleur et forme :SolidMasse moléculaire :380.47R-1479
CAS :R-1479 (4'-Azidocytidine) is an RdRp inhibitor with an IC50 value of 1.28 μM for HCV RNA replication in the HCV subgenomic replicon system.Formule :C9H12N6O5Degré de pureté :98.11% - 99.95%Couleur et forme :SolidMasse moléculaire :284.23Ref: TM-TQ0162
1mg104,00€5mg258,00€10mg358,00€25mg595,00€50mg842,00€100mg1.134,00€200mg1.521,00€1mL*10mM (DMSO)318,00€AD16
CAS :AD16 (Acetamide) acts as an inhibitor of LINE-1 retrotransposon endonuclease, exhibiting an IC50 value of 4.7 μM. It decreases LINE-1 retrotransposition in senescent cells and mitigates the resulting DNA damage and inflammation.Formule :C24H20N14O3S2Couleur et forme :SolidMasse moléculaire :616.64CBP501 Affinity Peptide
CAS :CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].Formule :C68H119N21O25SCouleur et forme :SolidMasse moléculaire :1662.86ROCK-IN-32
CAS :ROCK-IN-32 is an effective Rho-kinase inhibitor.Formule :C20H17Cl2N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.27Bimosiamose disodium
CAS :Bimosiamose disodium (TBC-1269Z), a pan-selectin inhibitor, has IC50s: E-selectin 88 μM, P-selectin 20 μM, L-selectin 86 μM; anti-inflammatory.Formule :C46H52Na2O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :906.88RP-1664
CAS :RP-1664,PLK4 inhibitor (IC50=3 nM). Disrupts centriole biogenesis. Antitumor activity in breast cancer, neuroblastoma.Formule :C23H24F2N8O2SDegré de pureté :99.04%Couleur et forme :SoildMasse moléculaire :514.55dCeMM3
CAS :dCeMM3 is a glue degrader that induces ubiquitination and degradation of cyclin K by promoting CDK12-cyclin K interaction with CRL4B ligase.
Formule :C14H11ClN4OSDegré de pureté :98.48% - 99.41%Couleur et forme :SolidMasse moléculaire :318.78Aclacinomycin A
CAS :Aclacinomycin A has a wide range of applications in life science related research.Formule :C42H53NO15Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :811.87(S)-DI-87
CAS :(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.Formule :C23H30N6O3S2Degré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :502.65Ref: TM-T39550L
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€5'(R)-C-Methyl-5-fluorouridine
5’(R)-C-Methyl-5-fluorouridine, a uridine analogue, possesses potential antiepileptic properties.Formule :C10H13FN2O6Couleur et forme :SolidMasse moléculaire :276.22CPS2
CAS :CPS2: potent, selective PROTAC CDK2 degrader. IC50=24nM, targets acute myeloid leukemia research.Formule :C38H42N12O10S2Couleur et forme :SolidMasse moléculaire :890.94BLINK15
BLINK15 is a blood-brain barrier-permeable Cdk5 inhibitor. It reduces CDK5 activity in CDK5/p35 (IC50= 29.34 nM) and CDK5/p25 (IC50= 12.08 nM) complexes. Additionally, BLINK15 exhibits antidiabetic and neuroprotective effects. It lowers blood glucose levels in type 2 diabetes (T2D) mice, enhances cognitive abilities, and diminishes neurodegenerative lesions.Couleur et forme :Odour SolidUridine triphosphate 13C9,15N2 sodium
CAS :Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04
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