Cycle cellulaire/point de contrôle
Les inhibiteurs du cycle cellulaire/des points de contrôle sont des composés qui perturbent la progression normale du cycle cellulaire, en particulier aux points de contrôle régulateurs clés. Ces inhibiteurs sont cruciaux pour étudier la division cellulaire, comprendre la prolifération des cellules cancéreuses et développer des thérapies anticancéreuses. En ciblant des phases spécifiques du cycle cellulaire, ces inhibiteurs peuvent induire un arrêt du cycle cellulaire, conduisant à l'apoptose ou à la sénescence des cellules à division rapide. Chez CymitQuimica, nous offrons une large gamme d'inhibiteurs de haute qualité du cycle cellulaire/des points de contrôle pour soutenir vos recherches en biologie du cancer, biologie cellulaire et développement de médicaments.
Sous-catégories appartenant à la catégorie "Cycle cellulaire/point de contrôle"
- Aurora Kinase(94 produits)
- CDK(500 produits)
- Arrêt du cycle cellulaire(4 produits)
- Chk(42 produits)
- DYRK(48 produits)
- Dynamine(23 produits)
- Ferroptose(215 produits)
- HSP(169 produits)
- Intégrine(224 produits)
- Kinésine(66 produits)
- LIM Kinase(19 produits)
- Microtubules associés(261 produits)
- PKC(102 produits)
- PLK(28 produits)
- ROCK(70 produits)
- Rho(2 produits)
- Wee1(15 produits)
- c-Myc(69 produits)
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3477 produits trouvés pour "Cycle cellulaire/point de contrôle"
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N1-Methylpseudouridine-5′-triphosphate tetralithium
<p>N1-Methylpseudouridine-5′-triphosphate tetralithium, also known as 1-Methylpseudouridine-5′-triphosphate tetralithium, is a nucleobase-modified nucleotide.</p>Formule :C10H13Li4N2O15P3Couleur et forme :SolidMasse moléculaire :521.9PAT-LM1
<p>PAT-LM1 is a human monoclonal antibody that targets NRB54/NONO. It is applicable in the study of hematological malignancies.</p>Couleur et forme :Odour LiquidMethylcarbamyl PAF C-8
<p>Methylcarbamyl PAF C-8 is resistant to degradation by PAF-AH and has a half-life of over 100 minutes in platelet-poor plasma, exhibiting platelet aggregation activity. In NRK-49 cells overexpressing PAF receptor, it induces the expression of c-myc, c-fos, and activates mitogen-activated protein kinase (MAPK). Furthermore, Methylcarbamyl PAF C-8 can induce G1 phase cell cycle arrest. This compound shows potential for research in cardiovascular and anti-cancer applications.</p>Couleur et forme :Odour Solidm7GpppGpG
CAS :<p>m7GpppGpG, a trinucleotide cap, protects mRNA from 5′ exonucleases & aids splicing and translation.</p>Formule :C31H41N15O25P4Couleur et forme :SolidMasse moléculaire :1147.64MRK-952
<p>MRK-952 is a NUDIX hydrolase inhibitor. NUDIX enzymes play a role in cellular metabolism, homeostasis, and mRNA processing.</p>Formule :C20H20ClF3N6Couleur et forme :SolidMasse moléculaire :436.861N3,5-Dimethyl-2'-O-(2-methoxyethyl) uridine
<p>N3,5-Dimethyl-2’-O-(2-methoxyethyl) uridine, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid malignancies.</p>Formule :C14H22N2O7Couleur et forme :SolidMasse moléculaire :330.33Stigmatellin
CAS :<p>Stigmatellin is an antibiotic derived from the cell mass of the myxobacterium, effective against yeasts (yeasts), filamentous fungi (filamentous fungi), and several Gram-positive bacteria (Gram-positive bacteria). Additionally, it serves as a potent inhibitor of photosynthetic electron (photosynthetic electron) transfer. Stigmatellin utilizes various sugars, polysaccharides, and acids from the citric acid cycle as substrates, inhibiting RNA and protein synthesis. It has two different inhibitory sites: one located on the reducing side of photosystem II and the other at the cytochrome b6/f complex. Stigmatellin holds potential for use in antimicrobial and photosynthesis research.</p>Formule :C30H42O7Couleur et forme :SolidMasse moléculaire :514.65PP-C8
<p>PP-C8: PROTAC CDK12-Cyclin K degrader with DC50s 416/412 nM; synergizes with PARP inhibitor against TNBC.</p>Formule :C43H51FN12O7Couleur et forme :SolidMasse moléculaire :866.94CDK5-IN-1
CAS :<p>CDK5-IN-1: Potent CDK5 inhibitor (<10 nM) used in kidney disease research.</p>Formule :C24H25FN6O3SCouleur et forme :SolidMasse moléculaire :496.56Ribonuclease T1
CAS :<p>Rnase T1, an endonuclease, degrades single-stranded RNA to yield 3'-GMP oligonucleotides.</p>Couleur et forme :SolidPD-1/PD-L1-IN-50
<p>Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.</p>Couleur et forme :Odour SolidRemdesivir nucleoside monophosphate
CAS :<p>Remdesivir metabolite, antiviral nucleoside analog, effective against SARS-CoV and MERS-CoV.</p>Formule :C12H14N5O7PCouleur et forme :SolidMasse moléculaire :371.24Sarecycline hydrochloride
CAS :<p>Sarecycline hydrochloride is a narrow-spectrum tetracycline antibiotic with antimicrobial and anti-inflammatory activity.</p>Formule :C24H30ClN3O8Degré de pureté :99.23%Couleur et forme :SolidMasse moléculaire :523.96CDK2/PIM1-IN-1
<p>CDK2/PIM1-IN-1 is an inhibitor of the kinases CDK2 (IC50: 0.27 μM) and PIM1 (IC50: 0.67 μM). It can induce apoptosis (cell death) and reduce the expression of TNF-α, which promotes tumors. CDK2/PIM1-IN-1 exhibits antitumor activity.</p>Couleur et forme :Odour SolidRifalazil
CAS :<p>Rifalazil (KRM-1648) is a benzophenazine antibiotic with antibacterial activity, useful for research on chlamydia infections.</p>Formule :C51H64N4O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :941.07JB-11 isethionate
CAS :<p>JB-11 isethionate is a bioactive chemical.</p>Formule :C21H29N5O7SCouleur et forme :SolidMasse moléculaire :495.55N1-Methyl-2'-O-(2-methoxyethyl) guanosine
<p>N1-Methyl-2’-O-(2-methoxyethyl) guanosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Formule :C14H21N5O6Couleur et forme :SolidMasse moléculaire :355.35Anticancer agent 84
CAS :<p>Anticancer agent 84 inhibits c-MYC transcription by stabilizing G4 structures, aiding cancer research.</p>Formule :C57H67N7O9Couleur et forme :SolidMasse moléculaire :994.18ROCK-IN-5
CAS :<p>ROCK-IN-5 (I-B-37) inhibits kinases like ROCK/ERK/GSK; may aid in cardiac and neuro disease studies.</p>Formule :C16H11ClFN3OSDegré de pureté :99.72% - 99.83%Couleur et forme :SolidMasse moléculaire :347.79L-Inosine
CAS :<p>L-Inosine, an endogenous purine nucleoside from adenosine metabolism, has anti-inflammatory, antinociceptive, immunomodulatory, and neuroprotective properties.</p>Formule :C10H12N4O5Couleur et forme :SolidMasse moléculaire :268.23PKMYT1-IN-3
<p>PKMYT1-IN-3 (compound 8ma) is a potent, selective inhibitor of PKMYT1, demonstrating an IC50 of 16.5 nM and exhibiting antitumor activity.</p>Formule :C24H26FN5O2Couleur et forme :SolidMasse moléculaire :435.49AB-3PRGD2
CAS :<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formule :C137H215IN30O45SCouleur et forme :SolidMasse moléculaire :3161.323'-Deoxyuridine-5'-triphosphate trisodium
<p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>Formule :C9H12N2Na3O14P3Couleur et forme :SoildMasse moléculaire :534.08TLR7 agonist 12
CAS :<p>TLR7 agonist 12, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis in lymphoid cancers.</p>Formule :C14H19N5O8Couleur et forme :SolidMasse moléculaire :385.332-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Formule :C12H24ClNO4Couleur et forme :SolidMasse moléculaire :281.783'-Deoxy-N1-Methyl inosine
<p>3’-Deoxy-N1-Methyl inosine, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Formule :C11H14N4O4Couleur et forme :SolidMasse moléculaire :266.25AURKA against 1
<p>Compound Ac13, also termed AURKA against 1, acts as an inhibitor of the Aurora kinase (AURKA) with an IC50 of less than 0.5 nM, targeting the acetylation of endogenous lysine (K162) and exhibiting anti-tumor cell proliferation activity. The kinase activity of AURKA, acetylated at K162 and induced by AURKA against 1, is reversibly restored in HCT116 cells transfected with SIRT3.</p>Formule :C28H32FN9O2Couleur et forme :SolidMasse moléculaire :545.612'-O-Methyl-5-methyluridine 5'-triphosphate triethylammonium
<p>2’-O-Methyl-5-methyluridine 5’-triphosphate (triethylammonium), a thymidine analog, exhibits insertional activity in replicated DNA.</p>Formule :C29H64N5O15P3Couleur et forme :SolidMasse moléculaire :815.76Pseudouridimycin
CAS :<p>Pseudouridimycin: a C-nucleoside antibiotic, inhibits bacterial RNAP, targets Gram-negative and Gram-positive bacteria.</p>Formule :C17H26N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :486.44BTO-1
CAS :<p>BTO-1: Plk inhibitor effective in regulating phosphorylation.</p>Formule :C9H4N4O4SCouleur et forme :SolidMasse moléculaire :264.22Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formule :C25H41N11O8SCouleur et forme :SolidMasse moléculaire :655.727Diguanosine 5′-triphosphate
CAS :<p>Diguanosine 5′-triphosphate (Gp3G) is a kind of homodinucleotide from by GTP:GTP guanylyltransferase.</p>Formule :C20H27N10O18P3Couleur et forme :SolidMasse moléculaire :788.409N3-(2S)-[2-(tert-Butoxycarbonyl)amino-3-(tert-butoxy carbonyl)]propyluridine
<p>N3-(2S)-propyluridine is a uridine analog with potential as an antiepileptic and for antihypertensive agent research.</p>Formule :C22H35N3O10Couleur et forme :SolidMasse moléculaire :501.53Mulnitorsen
CAS :<p>Mulnitorsen acts as an inhibitor of antisense non-coding mitochondrial RNA (ASncmtRNA) synthesis and serves as an antitumor agent [1].</p>Formule :C172H217N74O82P17S17Couleur et forme :SolidMasse moléculaire :5704.66EFdA-TP
CAS :<p>EFdA-TP: potent HIV-1 RT inhibitor; acts via immediate/delayed chain termination (ICT/DCT) and multiple pathways.</p>Formule :C12H15FN5O12P3Couleur et forme :SolidMasse moléculaire :533.1953'-O-(4,4'-Dimethoxy trityl)-2'-O-(2-methoxyethyl)-5-methyluridine
<p>3’-O-(4,4’-Dimethoxy trityl)-2’-O-(2-methoxyethyl)-5-methyluridine, a purine nucleoside analog, exhibits extensive antitumor properties against indolent</p>Formule :C34H38N2O9Couleur et forme :SolidMasse moléculaire :618.67Ascochlorin A
CAS :<p>Ascochlorin A, a compound with a dissociation constant (K D) of 3.29 μM, serves as a novel and potent human dihydroorotate dehydrogenase (hDHODH) inhibitor</p>Formule :C23H31ClO4Couleur et forme :SolidMasse moléculaire :406.955'-O-DMT-N4-Ac-2'-F-dC
CAS :<p>5’-O-DMT-N4-Ac-2’-F-dC is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C32H32FN3O7Couleur et forme :SolidMasse moléculaire :589.615'-O-DMT-PAC-dA
CAS :<p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>Formule :C39H37N5O7Couleur et forme :SolidMasse moléculaire :687.74CDK12-IN-6
CAS :<p>CDK12-IN-6, a pyrazolotriazine, strongly inhibits CDK12 (IC50 1.19 μM at 2 mM ATP), but not CDK2/Cyclin E or CDK9/Cyclin T1 (both IC50 >20 μM).</p>Formule :C20H21F2N9Couleur et forme :SolidMasse moléculaire :425.448Nuclease S1
CAS :<p>Nuclease S1 breaks down ssDNA and RNA, trims protruding ends of dsDNA.</p>Couleur et forme :Solid5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine
<p>5-(2-Hydroxyethyl)-2',3'-di-O-toluoyl-2'-deoxyuridine, a purine nucleoside analog, exhibits widespread antitumor activity specifically against indolent lymphoid</p>Formule :C27H28N2O8Couleur et forme :SolidMasse moléculaire :508.52JH-XVI-178
CAS :<p>JH-XVI-178: potent CDK8/19 inhibitor with good pharmacokinetics, low clearance, moderate oral bioavailability.</p>Formule :C22H22ClN7OCouleur et forme :SolidMasse moléculaire :435.92Trimethoprim hydrochloride
CAS :<p>Trimethoprim hydrochloride: oral, broad-spectrum antibiotic, DHFR inhibitor, treats UTIs, shigellosis, pneumocystis pneumonia, may block Influenza A with zinc.</p>Formule :C14H19ClN4O3Couleur et forme :SolidMasse moléculaire :326.78Eesperamicin A1
CAS :<p>Esperamicin A1, a powerful antitumor drug, comes from Actinomadura verrucosospora.</p>Formule :C59H80N4O22S4Couleur et forme :SolidMasse moléculaire :1325.542-Amino-6-O-methyl-2'-O-methyl purine riboside
<p>2-Amino-6-O-methyl-2’-O-methyl purine riboside, a purine nucleoside analog, exhibits broad antitumor activity, particularly against indolent lymphoid</p>Formule :C12H17N5O5Couleur et forme :SolidMasse moléculaire :311.29Carbazole
CAS :<p>Carbazole belongs to the class of carbazole-based organic compounds. Carbazole can form novel DNA small groove complexes, inhibiting the synthesis of new DNA or RNA.</p>Formule :C12H9NDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :167.211Fradafiban hydrochloride
<p>Fradafiban (BIBU-52) is a nonpeptide GPIIb/IIIa antagonist with Kd 148 nM for human platelets.</p>Formule :C20H22ClN3O4Couleur et forme :SolidMasse moléculaire :403.86m7GpppAmpG
CAS :<p>M7GpppAmpG is a trinucleotide 5′ cap analog, exhibiting capping efficiencies of 90% for the produced RNAs [1].</p>Formule :C32H43N15O24P4Couleur et forme :SolidMasse moléculaire :1145.66Rev 2'-O-MOE-A(Bz)-5'-amidite
<p>'Rev 2’-O-MOE-A(Bz)-5’-amidite is a nucleoside analog specifically categorized within the purine subset, renowned for its wide-ranging antitumor efficacy</p>Formule :C50H58N7O9PCouleur et forme :SolidMasse moléculaire :932.01SR15006
CAS :<p>SR15006 is Krüppel-like factor 5 (KLF5) inhibitor (IC50 = 41.6 nM).</p>Formule :C16H20ClN3O4SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :385.87cis-Lomibuvir
CAS :<p>cis-Lomibuvir (cis-VX-222) is a selective HCV NS5B RdRp inhibitor with a Kd of 17 nM and an EC50 of 5.2 nM, targeting thumb pocket 2.</p>Formule :C25H35NO4SCouleur et forme :SolidMasse moléculaire :445.61Heliquinomycin
CAS :<p>Heliquinomycin, a Streptomyces metabolite, inhibits DNA helicase (Ki=6.8 μM) and fights Gram-positive bacteria and various cancer cells.</p>Formule :C33H30O17Couleur et forme :SolidMasse moléculaire :698.586USP7-IN-10 hydrochloride
<p>USP7-IN-10 hydrochloride, also known as compound 1, is a potent inhibitor of the enzyme ubiquitin-specific protease 7 (USP7), exhibiting an IC50 value of 13.39</p>Formule :C26H30Cl2N4O3SCouleur et forme :SolidMasse moléculaire :549.51(1S,3R,5R)-PIM447 dihydrochloride
<p>(1S,3R,5R)-PIM447 (dihydrochloride) an inhibitor of PIM(IC50 of 0.095 μM for Pim1, 0.522 μM for Pim2 and 0.369 μM for Pim3).</p>Formule :C24H25Cl2F3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :513.385-O-TBDMS-N4-Benzoyl-2-deoxycytidine
CAS :<p>5-O-TBDMS-N4-Benzoyl-2-deoxycytidine is a modified nucleoside utilized in the synthesis of deoxyribonucleic acid (DNA) or nucleic acid.</p>Formule :C22H31N3O5SiCouleur et forme :SolidMasse moléculaire :445.581-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine
<p>1-(β-D-Xylofuranosyl)-N6-(m-methoxybenzyl)adenine is an adenosine analog.</p>Formule :C18H21N5O5Couleur et forme :SolidMasse moléculaire :387.396-Mthoxy-9-β-D-(2-C-ethynyl-ribofuranosyl) purine
<p>6-Methoxy-9-β-D-ethynyl-purine: a purine analog with antitumor action, impeding DNA synthesis and inducing apoptosis.</p>Formule :C13H14N4O5Couleur et forme :SolidMasse moléculaire :306.27N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-5-methyl-2'-deoxycytidine
<p>N4-Acetyl-5’-O-(4,4’-dimethoxytrityl)-5-methyl-2’-deoxycytidine, a purine nucleoside analog, exhibits broad antitumor activity particularly against indolent</p>Formule :C33H35N3O7Couleur et forme :SolidMasse moléculaire :585.65Ganodermaones B
<p>Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43Chrysomycin A
CAS :<p>Chrysomycin A is an antibiotic that can be derived from Streptomyces.</p>Formule :C28H28O9Couleur et forme :SolidMasse moléculaire :508.52Xylocytidine
CAS :<p>Xylocytidine is a biochemical.</p>Formule :C9H13N3O5Couleur et forme :SolidMasse moléculaire :243.22Biotin-PEG7-C2-NH-Vidarabine-S-CH3
<p>Biotin-PEG7-C2-NH-Vidarabine-S-CH3 is a PEG linker with Vidarabine, an anti-herpes/zoster antiviral.</p>Formule :C37H62N8O12S2Couleur et forme :SolidMasse moléculaire :875.06Mumefural
CAS :<p>Mumefural, from Prunus mume fruit, hinders platelets, has anti-thrombotic properties, and boosts cognition.</p>Formule :C12H12O9Couleur et forme :SolidMasse moléculaire :300.22Uridine-5-oxo-acetyl-(9-fluorenylmethyl) ester
<p>Uridine analogue with antitumor effects; inhibits DNA synthesis, induces apoptosis in lymphoid cancers.</p>Formule :C24H24N2O9Couleur et forme :SolidMasse moléculaire :484.4623-Oxa-OSW-1
CAS :<p>23-Oxa-OSW-1 (SBF-1), a derivative of OSW-1, serves as a potent inhibitor of the osterol-binding protein (OSBP) with demonstrated antitumor activity [1] [2].</p>Formule :C54H82O16Couleur et forme :SolidMasse moléculaire :987.22Rev 2'-O-MOE-C(Bz)-5'-amidite
<p>'Rev 2’-O-MOE-C(Bz)-5’-amidite, a purine nucleoside analog, exhibits broad antitumor activity against indolent lymphoid malignancies.</p>Formule :C49H58N5O10PCouleur et forme :SolidMasse moléculaire :907.99GSK299423
CAS :<p>GSK299423: Antibiotic possibly effective against bacteria with New Delhi metal-β-lactamase, targeting topoisomerases.</p>Formule :C25H27N5O2SDegré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :461.58JB300
CAS :<p>JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.</p>Formule :C43H45ClFN7O10SCouleur et forme :SolidMasse moléculaire :906.3755-Iminodaunorubicin
CAS :<p>5-Iminodaunorubicin: a quinone-altered anthracycline with antitumor effects, causing DNA breaks in cancer.</p>Formule :C27H30N2O9Couleur et forme :SolidMasse moléculaire :526.546-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
<p>6-Amino-4-hydrozino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue with broad antitumor activity, particularly against</p>Formule :C10H15N7O4Couleur et forme :SolidMasse moléculaire :297.27IBU-DC Phosphoramidite
CAS :<p>IBU-DC Phosphoramidite is used for synthesis of oligonucleotides.</p>Formule :C43H54N5O8PCouleur et forme :SolidMasse moléculaire :799.9065'-O-TBDMS-dA
CAS :<p>5’-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.</p>Formule :C16H27N5O3SiCouleur et forme :SolidMasse moléculaire :365.5095'-O-DMTr-2',2'-difluoro-dC(Bz)-methyl phosphonamidite
<p>5’-O-DMTr-2’,2’-difluoro-dC(Bz)-methyl phosphonamidite is a purine nucleoside analog with extensive antitumor activity against indolent lymphoid malignancies.</p>Formule :C44H49F2N4O7PCouleur et forme :SolidMasse moléculaire :814.85WAY-647802
CAS :<p>WAY-647802 is a CDK inhibitor.</p>Formule :C11H14N4O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :250.25Brr2-IN-2
<p>Brr2-IN-2 (Compound 30) is an inhibitor of Brr2, exhibiting an IC50 of 42 nM against Brr2 ATPase.</p>Formule :C21H25FN4O2Couleur et forme :SolidMasse moléculaire :384.45Anticancer agent 263
<p>Anticanceragent 263 (compound 7) is an effective anticancer agent. It binds with the G-quadruplex DNA (G4) sequence 22-mer Pu22 (a c-Myc DNA analog). As a structural modulator, Anticanceragent 263 significantly enhances the formation of protein α-helices and has the capacity to form a supramolecular network. Furthermore, Anticanceragent 263 exhibits no cytotoxicity.</p>Formule :C13H20N2O6Couleur et forme :SolidMasse moléculaire :300.308N2-Acetylguanine
CAS :<p>Compound 19962-37-9, with CAS No. 19962-37-9, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound 19962-37-9 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C7H7N5O2Degré de pureté :99.90%Couleur et forme :White SolidMasse moléculaire :193.166Obtustatin
<p>Potent α1β1 integrin inhibitor, 0.8 nM IC50 for IV collagen binding. Selective over other integrins. Inhibits FGF2 angiogenesis; antitumor in mouse models.</p>Formule :C184H284N52O57S8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :4393.0713-TP
<p>13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.</p>Formule :C12H19F2N6O12P3Couleur et forme :SolidMasse moléculaire :570.23CBP501 Affinity Peptide
CAS :<p>CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].</p>Formule :C68H119N21O25SCouleur et forme :SolidMasse moléculaire :1662.86CDK2/4-IN-1
<p>CDK2/4-IN-1 (compound B-4a) serves as both a CDK2/4 inhibitor and a microtubule polymerization inhibitor, making it useful in cancer research.</p>Couleur et forme :Odour Solid2'-Deoxy-2'-fluoroguanosine 5'-monophosphate triethyl ammonium
<p>2’-Deoxy-2’-fluoroguanosine 5’-monophosphate triethyl ammonium, a purine nucleoside analog, exhibits broad antitumor activity specifically targeting indolent</p>Formule :C22H43FN7O7PCouleur et forme :SolidMasse moléculaire :567.59Lysidine
CAS :<p>Lysidine (2-Methyl-2-iMidazoline) is a nucleoside rarely seen outside of tRNA. Lysidine has better translation fidelity.</p>Formule :C4H8N2Degré de pureté :98%Couleur et forme :Light Yellow To Off-White CrystallineMasse moléculaire :84.12Dafsolimab
CAS :<p>Dafsolimab (SPV-T3a), an IgG2a murine monoclonal antibody (anti-CD3), induces cell death by modulating and activating the CD3/T cell receptor complex and is</p>Couleur et forme :LiquidCGP-74514
CAS :<p>CGP-74514,CDK1 inhibitor (IC50=25 nM). Induces G2/M arrest, apoptosis. Used in bladder cancer research.</p>Formule :C19H24ClN7Degré de pureté :98.54%Couleur et forme :SoildMasse moléculaire :385.89DNA Gyrase-IN-17
<p>DNA Gyrase-IN-17 (Compound 5C) is an inhibitor of DNA gyrase. It demonstrates significant antimicrobial activity against a range of Gram-positive and Gram-negative strains, including Enterococcus faecium, Escherichia coli, and Pseudomonas aeruginosa, with a MIC value of 62.5 μg/mL. By inhibiting bacterial DNA gyrase, DNA Gyrase-IN-17 disrupts DNA replication. This compound can be useful in the development of antibiotics, particularly for studying resistant strains.</p>Formule :C18H15ClFN5OCouleur et forme :SolidMasse moléculaire :371.094925'-O-DMT-rI
CAS :<p>5’-O-DMT-Ri can be used in the synthesis of oligoribonucleotides[1].</p>Formule :C31H30N4O7Couleur et forme :SolidMasse moléculaire :570.59N6-Methyladenine
CAS :<p>N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants.</p>Formule :C6H7N5Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :149.15CDK9/EZH2-IN-1
CAS :<p>CDK9/EZH2-IN-1 is a dual-target inhibitor of CDK9 and EZH2 with IC50 values of 83.9 nM and 108.6 nM, respectively. It induces apoptosis and causes DNA double-strand breaks (DSB). Additionally, CDK9/EZH2-IN-1 inhibits the proliferation of MKN45, MDA-MB-453, and SW620 cancer cells, with respective IC50 values of 136.3 nM, 171.3 nM, and 315.7 nM.</p>Formule :C47H59N11O4S2Couleur et forme :SolidMasse moléculaire :906.17Pseudorabies virus-IN-1
<p>Pseudorabies virus-IN-1 is a potent inhibitor of pseudorabies virus (PRV) with an EC50 of 0.29 nM, acting by targeting PRV deoxyribonucleic acid polymerase (DNA pol) to suppress PRV replication. It effectively inhibits PRV replication even at low concentrations (MIC80: 1.6-8 nM) and is useful for research on PRV infections.</p>Formule :C27H23ClF2N4O2Couleur et forme :SolidMasse moléculaire :508.947ONX 0801 trisodium
CAS :<p>ONX 0801 (BGC 945) trisodium is a targeted thymidylate synthase (TS) inhibitor specifically designed to act against tumors overexpressing the α-folate receptor.</p>Formule :C32H30N5Na3O10Couleur et forme :SolidMasse moléculaire :713.582'-Fluoro-2'-deoxy-arabinoadenosine 5'-triphosphate triethylamine
<p>2’-Fluoro-2’-deoxy-arabinoadenosine 5’-triphosphate (triethylamine) is a purine nucleoside analog with significant antitumor properties, particularly effective</p>Formule :C34H75FN9O12P3Couleur et forme :SolidMasse moléculaire :913.93P8RI acetate
<p>P8RI acetate mimics CD31, activates CDP8RI, and suppresses the immune response by restoring CD31 pathway.</p>Formule :C53H81N13O11Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :1076.29N6-Ethyl-2'-β-C-ethynyl adenosine
<p>N6-Ethyl-2’-beta-C-ethynyl adenosine is a purine nucleoside analog.</p>Formule :C14H17N5O4Couleur et forme :SolidMasse moléculaire :319.32Py-MAA-Val-Cit-PAB-DX8951
CAS :<p>Py-MAA-Val-Cit-PAB-DX8951, a purine toxin, serves as an intermediate in the synthesis of antibody-drug conjugates [1].</p>Formule :C57H66FN11O13SCouleur et forme :SolidMasse moléculaire :1164.26MS133
<p>MS133 is a human bispecific antibody targeting CD133/PROM1 and CD3E. It is used in the study of colon cancer.</p>Couleur et forme :Odour LiquidDitercalinium chloride
CAS :<p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>Formule :C46H50Cl2N6O2Couleur et forme :SolidMasse moléculaire :789.83MAP3K5-IN-1
CAS :<p>Compound 7, also known as 3′-O-Demethyl-4′-N-demethyl-4′-N-acetyl-4′-epi-staurosporine, serves as an inhibitor of protein kinases, displaying IC50 values of 0.092 μM for PKC-α, 0.26 μM for ROCK, and 0.77 μM for ASK1. Additionally, this compound exhibits significant cytotoxicity towards PC-3 cancer cells, with an IC50 of 0.16 μM [1].</p>Formule :C28H24N4O4Couleur et forme :SolidMasse moléculaire :480.51A20FMDV2
CAS :<p>A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.</p>Formule :C93H163N31O28Couleur et forme :SolidMasse moléculaire :2163.486-Thioguanosine
CAS :<p>6-Thioguanosine (6-Mercaptoguanosine) is an active nucleoside and low molecular weight gel.6-Thioguanosine has immunosuppressive properties.</p>Formule :C10H13N5O4SDegré de pureté :97.05%Couleur et forme :Yellow-Green PowderMasse moléculaire :299.31Integrin Binding Peptide
CAS :<p>Integrin Binding Peptide, derived from fibronectin, holds the potential as an essential component for preparing PEG hydrogels.</p>Formule :C42H63N15O16SCouleur et forme :SolidMasse moléculaire :1066.12PROTAC CDK9 degrader 4
CAS :<p>PROTAC CDK9 degrader 4 is a CDK9 degrader that targets transcriptional regulation and has potential anticancer activity.</p>Formule :C43H56N10O5Couleur et forme :SolidMasse moléculaire :792.97Filanesib TFA
CAS :<p>Filanesib (ARRY-520) inhibits KSP, triggering mitotic arrest and cell death in dividing tumor cells.</p>Formule :C22H23F5N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5ML-60218
CAS :<p>ML-60218 inhibits RNA pol III in yeast/humans with IC50s of 32/27 μM; disrupts and prevents viroplasms.</p>Formule :C19H15Cl2N3O2S2Degré de pureté :98.1%Couleur et forme :SolidMasse moléculaire :452.38N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium
CAS :<p>N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].</p>Formule :C21H35N12O17P3Couleur et forme :SolidMasse moléculaire :820.49STX-100
<p>PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.</p>Degré de pureté :97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :Odour LiquidHEMTAC WEE1 degrader-1
CAS :<p>HEMTACWEE1degrader-1 is a WEE1-targeting heterobifunctional chimeric degrader (HEMTAC) facilitated by HSP90, exhibiting an HSP90 enzyme inhibitory activity with an IC50 of 16.76 nM. It enhances the ubiquitination and subsequent degradation of WEE1, effectively blocking the G2/M cell cycle transition. This compound shows anticancer properties in patient-derived xenograft (PDX) models of acute myeloid leukemia (AML). HEMTACWEE1degrader-1 is utilized in AML research.</p>Formule :C57H71N15O6Couleur et forme :SolidMasse moléculaire :1062.27TS-002266
CAS :<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Formule :C31H32Cl2N6O5Degré de pureté :98.18%Couleur et forme :SoildMasse moléculaire :639.53GSK-1070916
CAS :<p>GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.</p>Formule :C30H33N7ODegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :507.63dAURK-4
CAS :<p>dAURK-4, a derivative of Alisertib, functions as a potent and selective degrader of AURKA (Aurora A), exhibiting anticancer properties [1].</p>Formule :C52H52ClFN8O12Couleur et forme :SolidMasse moléculaire :1035.473,6-DMAD hydrochloride
<p>3,6-DMAD hydrochloride functions as an inhibitor for the IRE1α-XBP1 pathway within the unfolded protein response mechanism.</p>Formule :C22H31N5xHClDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.52DG1
<p>DG1 (Compound 8Nc), a Thymidylate Synthase (TS) inhibitor, impedes angiogenesis and alters metabolic reprogramming in NSCLC cells, while effectively suppressing</p>Formule :C19H17N5O5SCouleur et forme :SolidMasse moléculaire :427.43Adenosine 5′-O-1-thiotriphosphate (disodium)
<p>Adenosine 5′-O-(1-thiotriphosphate) (disodium) is an adenosine nucleotide modified at the alpha-phosphate.</p>Formule :C10H14N5Na2O12P3SMasse moléculaire :566.93679MUS81-IN-1
<p>MUS81-IN-1 (compound 23) is an MUS81 inhibitor, utilized in cancer research.</p>Formule :C23H21N3O5Masse moléculaire :419.14812DHFR-IN-18
<p>DHFR-IN-18 (compound 19D) is a DHFR inhibitor utilized in leukemia-related research.</p>Formule :C24H22ClN7Masse moléculaire :443.16252dsDNase
<p>dsDNase is a highly specific endonuclease for double-stranded DNA (dsDNA) that can rapidly and efficiently eliminate contaminant DNA from PCR master mixes.</p>(Gly0.8Nap0.2)20
<p>(Gly0.8Nap0.2)20 is a dual-target compound effective against fungal membranes and DNA. It exhibits antimicrobial properties.</p>Formule :C139H236N38O24·16(C2F3O2)K34c hydrochloride
CAS :<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formule :C26H30ClN3O4Degré de pureté :99.76% - 99.89%Couleur et forme :SoildMasse moléculaire :483.995'-O-DMT-N2-DMF-dG
CAS :<p>5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.</p>Formule :C34H36N6O6Couleur et forme :SolidMasse moléculaire :624.698Lamifiban trifluoroacetate
CAS :<p>Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa).</p>Formule :C26H29F3N4O8Couleur et forme :SolidMasse moléculaire :582.533NUAK1-IN-1
<p>NUAK1-IN-1 (Compound 9) is an inhibitor of NUAK1 with an IC50 of 5.012 nM, as well as a CDK4 inhibitor. It is suitable for research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.</p>Formule :C25H30N6OCouleur et forme :SolidMasse moléculaire :430.5457-TFA-ap-7-Deaza-ddA
CAS :<p>Compound 19c is a nucleotide derivative for DNA sequencing dye terminators.</p>Formule :C16H16F3N5O3Couleur et forme :SolidMasse moléculaire :383.331CDK12/13-IN-2
<p>CDK12/13-IN-2 (Compound 24) is a covalent inhibitor of CDK12 and CDK13, exhibiting IC50 values of 15.5 nM and 12.2 nM, respectively. It effectively inhibits the proliferation of breast cancer cells and can be utilized in the research of triple-negative breast cancer.</p>Formule :C24H22FN7O2Couleur et forme :SolidMasse moléculaire :459.48USP7-IN-16
CAS :<p>USP7-IN-16 (Compound 61) is a selective inhibitor of USP7, with IC50 values of 5.5 nM in the FLINT assay and 2.1 nM in MM.1S cells. This compound exhibits antitumor activity in mice and holds potential for research in the field of oncology.</p>Formule :C43H45N7O6SCouleur et forme :SolidMasse moléculaire :787.93PKMYT1-IN-6
<p>PKMYT1-IN-6 (compound 98) is an inhibitor of PKMYT1, exhibiting an IC50 of less than 50nM.</p>Couleur et forme :Odour SolidAV-153
CAS :<p>AV-153, a 1,4-dihydropyridine, reduces DNA damage, stimulates repair, and has anti-cancer properties.</p>Formule :C14H19NNaO6Couleur et forme :SolidMasse moléculaire :320.297N1-Benzoyl pseudouridine
<p>N1-Benzoyl pseudouridine, a purine nucleoside analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Formule :C16H16N2O7Couleur et forme :SolidMasse moléculaire :348.314-Amino-1-(2-C-methyl-β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS :<p>4-Amino-5-cyano-1-(2-β-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine, a purine nucleoside analogue, exhibits widespread antitumor efficacy,</p>Formule :C13H15N5O4Couleur et forme :SolidMasse moléculaire :305.29ICAM-1988
CAS :<p>ICAM-1988 is a LFA-1 antagonist.</p>Formule :C22H22Cl2N4O6SCouleur et forme :SolidMasse moléculaire :541.4DHFR-IN-11
<p>DHFR-IN-11 (compound 6b) is a DHFR inhibitor with demonstrated inhibitory efficacy against the M.</p>Couleur et forme :Odour SolidCW-2
<p>CW-2 is a PARP1 PROTAC degrader known for its potent antiproliferative effects against MDA-MB-231 cells (IC50 = 0.72 μM) and cisplatin-resistant cells (A549/CDDP: IC50 = 3.52 μM). It exhibits synergistic antitumor activity and enhanced membrane permeability. CW-2 exerts its antitumor effects by inducing DNA damage, disrupting DNA repair, and triggering mitochondrial-dependent apoptosis (apoptosis).</p>Formule :C43H42Cl2FN11O10PtCouleur et forme :SolidMasse moléculaire :1156.21251PROTAC CDK9 degrader-5
CAS :<p>PROTAC CDK9 degrader-5 selectively degrades CDK9 isoforms 42, 55 with DC50 of 0.10μM, 0.14μM via proteasome.</p>Formule :C42H48Cl2N8O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :879.78Nusinersen
CAS :<p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>Degré de pureté :98.62%Couleur et forme :Solid(S)-DI-87
CAS :<p>(S)-DI-87 is an isomer of DI-87, a oral dCK inhibitor，reduce dNTP production and cell cycle arrest. significantly inhibits tumor growth with thymidine.</p>Formule :C23H30N6O3S2Degré de pureté :99.42%Couleur et forme :SoildMasse moléculaire :502.65Cdk2/Cyclin Inhibitory Peptide I
<p>CDK2, a Ser/Thr kinase, is akin to yeast cdc28 and human Cdk1, crucial for cell division.</p>Formule :C111H196N48O23Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2571.05TS-002902
<p>TS-002902 is a small molecule inhibitor of TUT4/7, exhibiting antiproliferative activity. It holds potential for use in cancer research.</p>Couleur et forme :Odour Solid8-NH2-ATP
CAS :<p>8-NH2-ATP is an inactive derivative of adenosine triphosphate (ATP), synthesized from 8-NH2-Ado.</p>Formule :C10H17N6O13P3Couleur et forme :SolidMasse moléculaire :522.20CDK8-IN-12
CAS :<p>CDK8-IN-12: selective CDK8 inhibitor (Ki 14 nM), oral anticancer, blocks GSK-3α/β, PCK-θ, halts MV4-11 cell growth.</p>Formule :C21H20ClN3O2Degré de pureté :99.46% - 99.83%Couleur et forme :SoildMasse moléculaire :381.86HDAC-IN-85
<p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>Formule :C24H27FN4O5Couleur et forme :SolidMasse moléculaire :470.49YL-5092
<p>YL-5092 is an inhibitor of YT521-B homology (YTH) domain-containing protein 1 (YTHDC1). It inhibits acute myeloid leukemia cells with an IC50 of 0.28-2.87 μM. YL-5092 exhibits antitumor activity in xenograft mice models using MOLM-13 or U937 cells.</p>Formule :C22H14F3N3O2SCouleur et forme :SolidMasse moléculaire :441.43Vanoxonin
CAS :<p>Vanoxonin is a new thymidylate synthetase inhibitor.</p>Formule :C18H25N3O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :427.41Guanosine triphosphate
CAS :<p>Guanosine triphosphate (GTP), a native nucleotide, and its derivatives may serve as specific inhibitors against COVID-19 [1].</p>Formule :C10H16N5O14P3Couleur et forme :SolidMasse moléculaire :523.185'-ODMT cEt G Phosphoramidite (Amidite)
CAS :<p>5'-ODMT cEt G Amidite is a safe, effective nucleic acid analog with strong antisense activity.</p>Formule :C46H56N7O9PCouleur et forme :SolidMasse moléculaire :881.95Cytarabine triphosphate
CAS :<p>Ara-CTP, active Cytarabine metabolite, inhibits DNA synthesis, predicts leukemic chemosensitivity.</p>Formule :C9H16N3O14P3Couleur et forme :SolidMasse moléculaire :483.16FR901463
CAS :<p>FR 901463 is a biochemical.</p>Formule :C27H42ClNO8Couleur et forme :SolidMasse moléculaire :544.08LDV FITC
CAS :<p>fluorescent ligand that binds to the α4β1 integrin (VLA-4)</p>Formule :C69H81N11O17SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1368.53PROTAC MPS1 degrader 2
<p>PROTAC MPS1 Degrader 2 (Compound 15) is a potent degrader of monopolar spindle 1 (Mps1, TTK), AURKA, and AURKB with DC50 values of 42.0, 2.1, and 154.0 nM respectively. It is utilized in the research of acute myeloid leukemia.</p>Formule :C41H41N11O8SCouleur et forme :SolidMasse moléculaire :847.90Carboxy pyridostatin trifluoroacetate salt
<p>Carboxy pyridostatin trifluoroacetate salt exhibits higher molecular specificity for RNA over DNA G4s.</p>Formule :C37H35F3N10O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :820.73dCeMM3
CAS :<p>dCeMM3 is a glue degrader that induces ubiquitination and degradation of cyclin K by promoting CDK12-cyclin K interaction with CRL4B ligase.</p>Formule :C14H11ClN4OSDegré de pureté :98.48% - 99.41%Couleur et forme :SolidMasse moléculaire :318.78DENV-IN-2
CAS :<p>DENV-IN-2 inhibits dengue virus replication (EC50: 0.016 nM), affects all serotypes (EC50: 0.013-0.029 nM). Derived from WO2018215315A1 6AB.</p>Formule :C29H26ClF3N2O6Couleur et forme :SolidMasse moléculaire :590.98TMX-2138
CAS :<p>TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.</p>Formule :C40H43BrFN9O11SCouleur et forme :SolidMasse moléculaire :956.791Uridine triphosphate 13C9,15N2 sodium
CAS :<p>Uridine triphosphate 13C9,15N2 sodium is an isotopically labeled.UTP is a key in RNA synthesis molecule a substrate for RNA polymerase.</p>Formule :C9H1415N2NaO15P3Couleur et forme :SolidMasse moléculaire :517.04Activated Protein C (390-404), human TFA
<p>APC's 390-404 peptide region key to anticoagulation, binds antibodies/proteins, inactivates cofactors Va/VIIIa.</p>Formule :C93H131F3N22O25Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2014.165-Caroxy uracil-1-yl acetic acid benzyl ester
<p>5-Caroxy uracil-1-yl acetic acid benzyl ester, a purine analog, inhibits DNA synthesis and induces apoptosis to combat lymphoid cancers.</p>Formule :C14H12N2O6Couleur et forme :SolidMasse moléculaire :304.25Etrolizumab
CAS :<p>MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.</p>Degré de pureté :98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidBesufetamig
CAS :<p>Besufetamig is a bispecific antibody targeting programmed cell death protein 1 (PD-1) and the CD3ε chain. It modulates immune cell activity, exerting both immunosuppressive and antitumor effects. Besufetamig holds promise for cancer research.</p>Couleur et forme :Liquid2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)
CAS :<p>dGMP is a substrate for DNA synthesis, phosphorylated to dGDP and dGTP, and linked to mitochondrial DNA depletion syndrome in humans.</p>Formule :C10H14N5Na2O8PCouleur et forme :SolidMasse moléculaire :409.202DSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidCDK9-IN-25
<p>CDK9-IN-25 (compound 4a), an imidazopyrazine derivative, functions as a CDK9 inhibitor with an IC50 of 0.24 μM.</p>Formule :C15H16FN5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :285.32Risuteganib
CAS :<p>Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.</p>Formule :C22H39N9O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :637.66TH1085
CAS :<p>TH1085 is an enhancer of OGG1. TH1085 stimulates DNA repair and protects cells from the environmental hazard paraquat (PQ).</p>Formule :C17H21N3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :267.37DHODH-IN-16
CAS :<p>DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).</p>Formule :C24H25FN4O3Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :436.487-TFA-ap-7-Deaza-ddG
CAS :<p>Compound 19d, a nucleotide derivative, is used to make thiotriphosphate dye terminators for DNA sequencing.</p>Formule :C16H16F3N5O4Couleur et forme :SolidMasse moléculaire :399.33Cotylenin A
CAS :<p>Cotylenin A is a phenanthraquinone compound that synergistically works with vitamin K2 to induce monocyte differentiation and growth arrest. It also inhibits c-Myc expression while inducing cyclin G2 expression in human leukemia HL-60 cells. Cotylenin A is applicable in acute myeloid leukemia research.</p>Formule :C33H50O11Couleur et forme :SolidMasse moléculaire :622.744Erythromycin A dihydrate
CAS :<p>Erythromycin dihydrate, a macrolide antibiotic from Streptomyces erythreus, targets 50S ribosomal subunits, blocking protein synthesis.</p>Formule :C37H69NO14Couleur et forme :SolidMasse moléculaire :751.94CDK2-IN-7
CAS :<p>CDK2-IN-7 is a CDK2 inhibitor for treating cancer ( IC 50 < 50 nM).</p>Formule :C24H30N6O4SCouleur et forme :SolidMasse moléculaire :498.6wrwycr-NH2 TFA
<p>wrwycr-NH2 (TFA) is a peptide that exhibits cytotoxic properties against various cancer cells, inducing DNA damage and cell cycle arrest without causing endoplasmic reticulum stress. It possesses antitumor activity, and its efficacy is enhanced when used in combination with DNA-damaging agents.</p>Couleur et forme :Odour SolidEmicoron
CAS :<p>Importazole is an inhibitor of the transport receptor importin-β. It specifically inhibits importin-β likely by altering its interaction with RanGTP.</p>Formule :C52H58N6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :831.055'-DMT-3'-TBDMS-Bz-rA
CAS :<p>5'-DMT-3'-TBDMS-Bz-rA is a nucleoside with protective and modification effects.</p>Formule :C44H49N5O7SiCouleur et forme :SolidMasse moléculaire :787.975-O-benzoyl-1,2-O-isopropylidene-α-D-erythro-pent-3-ulofuranose
CAS :<p>5-O-benzoyl-1,2-O-isopropylidene-alpha-D-erythro-pent-3-ulofuranose is a Carbohydrate; Used for modified nucleoside.</p>Formule :C15H16O6Couleur et forme :SolidMasse moléculaire :292.282',3'-Dideoxy-3'-fluorouridine
CAS :<p>Nucleoside Derivatives - 2’,3’-Dideoxy nucleosides, Fluoro-modified nucleosides, 3’-Modified nucleosides; Drugs and Inhibitors; Anti-HIV agent</p>Formule :C9H11FN2O4Couleur et forme :SolidMasse moléculaire :230.193'-O-(2-Azidoethyl)adenosine
<p>Nucleoside Derivatives - 3’-Modified nucleosides; Azido-nucleosides</p>Couleur et forme :Soild3'-O-t-Bulyldimethylsilyl thymidine
CAS :<p>Nucleosides - 2’-deoxynucleoside</p>Formule :C16H28N2O5SiCouleur et forme :SolidMasse moléculaire :356.492'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine
CAS :<p>2'-Deoxy-2'-fluoro-b-D-arabino-6-azauridine is a Nucleoside Derivative - 6-Aza-uridine; Fluoro-modified nucleoside; Arabino nucleoside.</p>Formule :C8H10FN3O5Couleur et forme :SolidMasse moléculaire :247.18N6-Acetyl adenosine
CAS :<p>Nucleoside Derivatives –Naturally modified ribo-nucleosides;Other modified nucleosides</p>Formule :C12H15N5O5Couleur et forme :SolidMasse moléculaire :309.28N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine
<p>N1-Methyl-2'-deoxy-2'-fluoroarabinoadenosine is a Nucleoside Derivative - 2'-Modified nucleoside, N-Methylated/alkylated nucleoside, Fluoro-modified nucleoside.</p>Couleur et forme :Soild2'-O-(2-Methoxyethyl) inosine
CAS :<p>2'-O-(2-Methoxyethyl) inosine is a Nucleoside Derivative - 2'-Modified nucleoside.</p>Formule :C13H18N4O6Couleur et forme :SolidMasse moléculaire :326.312'-O-Acetyl-3'-azido-5'-O-(p-Toluoyl))-3'-deoxyuridine
CAS :<p>Nucleoside Derivatives - 3’-Modified nucleoside, Azido-nucleosides</p>Formule :C19H19N5O7Couleur et forme :SolidMasse moléculaire :429.382'-β-C-Methyl inosine
CAS :<p>2'-beta-C-Methyl inosine (2'-C-Methyl inosine) is an HCV RNA polymerase inhibitor with antiviral activity and may be used in studies to treat hcv infections.</p>Formule :C11H14N4O5Couleur et forme :SolidMasse moléculaire :282.252'-Deoxy-5,N4-dimethylcytidine
CAS :<p>2'-Deoxy-5,N4-dimethylcytidine is a Nucleoside Derivative - N-Methylated nucleoside.</p>Formule :C11H17N3O4Couleur et forme :SolidMasse moléculaire :255.275-(2,3,5-Tri-O-benzyl-β-D-ribofuranosyl)-3-methyl-2-benzyloxypyridine
CAS :<p>Nucleoside Derivatives - C-Nucleosides, Pyridine nucleosides</p>Formule :C39H39NO5Couleur et forme :SolidMasse moléculaire :601.736-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine
CAS :<p>6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine is a Nucleoside Derivative - Other modified nucleoside.</p>Formule :C10H13N5O3Couleur et forme :SolidMasse moléculaire :251.248-Nitroguanosine
CAS :<p>8-Nitroguanosine is a Nucleoside Derivative - 8-Modified purine nucleoside.</p>Formule :C10H12N6O7Couleur et forme :SolidMasse moléculaire :328.243'-deoxy-3'-fluoro-β-D-xylo-inosine
CAS :<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 3’-Modified nucleosides; Xylo-nucleosides</p>Formule :C10H11FN4O4Couleur et forme :SolidMasse moléculaire :270.222'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine
CAS :<p>2'-O-Acetyl-5'-O-(p-toluoyl)-3'-deoxy-3'-fluoro-5-fluorouridine is a Nucleoside Derivative - Fluoro-modified nucleoside, 5-modified pyrimidine nucleoside, 3'-</p>Formule :C19H18F2N2O7Couleur et forme :SolidMasse moléculaire :424.352'-Deoxy-2'-fluoro-5-hydroxymethyl arabinouridine
CAS :<p>Nucleoside Derivatives - Fluoro-modified nucleosides; 2’-Modified nucleosides; 5-Modified pyrimidine nucleosides; Metabolite of FMAU</p>Formule :C10H13FN2O6Couleur et forme :SolidMasse moléculaire :276.222'-Deoxy-6-azauridine
CAS :<p>2’-Deoxy-6-azauridine is a useful organic compound for research related to life sciences. The catalog number is TNU1081 and the CAS number is 20500-29-2.</p>Formule :C8H11N3O5Couleur et forme :SolidMasse moléculaire :229.192',3',5'-Tri-O-Benzoyl-4'-thiouridine
CAS :<p>2',3',5'-Tri-O-Benzoyl-4'-thiouridine is a Thio-nucleoside.</p>Formule :C30H24N2O8SCouleur et forme :SolidMasse moléculaire :572.593'-O-t-Butyldimethylsilyl adenosine
CAS :<p>3'-O-t-Butyldimethylsilyl adenosine is a Nucleoside; Used for special nucleoside modification.</p>Formule :C16H27N5O4SiCouleur et forme :SolidMasse moléculaire :381.56-Deoxo-8-oxo-3'-deoxy-guanosine
<p>6-Deoxo-8-oxo-3’-deoxy-guanosine is a useful organic compound for research related to life sciences and the catalog number is TNU1451.</p>Couleur et forme :Soild(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol
CAS :<p>(1S)-1,4-Anhydro-1-C-(2,4-difluorophenyl)-D-ribitol is a Nucleoside Derivative - C-nucleoside; Fluoro-modified nucleoside.</p>Formule :C11H12F2O4Couleur et forme :SolidMasse moléculaire :246.21DMTr-LNA-G(iBu)-3'-CED-phosphoramidite
CAS :<p>Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phosphoramidites</p>Formule :C45H54N7O9PCouleur et forme :SolidMasse moléculaire :867.935-(Aminomethyl)-2-thiouridine
CAS :<p>Nucleoside Derivatives - 5-Modified pyrimidine nucleosides; Thio-nucleosides; Amino nucleosides; Naturally modified ribo-nucleosides</p>Formule :C10H15N3O5SCouleur et forme :SolidMasse moléculaire :289.31N6-Methyl-xylo-adenosine
CAS :<p>N6-Methyl-xylo-adenosine is a Nucleoside Derivative - Xylo-nucleoside;6-Substituted purine nucleoside.</p>Formule :C11H15N5O4Couleur et forme :SolidMasse moléculaire :281.272-Deoxy-2'-deoxyuridine
CAS :<p>2-Deoxy-2'-deoxyuridine is a Nucleoside Derivative - 2-Deoxy uridine.</p>Formule :C9H12N2O4Couleur et forme :SolidMasse moléculaire :212.22-Methoxy-2'-deoxyadenosine
CAS :<p>2-Methoxy-2'-deoxyadenosine is a Nucleoside Derivative - 2-Modified purine nucleoside.</p>Formule :C11H15N5O4Couleur et forme :SolidMasse moléculaire :281.272'-Deoxy-2'-iodouridine
CAS :<p>2'-Deoxy-2'-iodouridine is a Halo-nucleoside.</p>Formule :C9H11IN2O5Couleur et forme :SolidMasse moléculaire :354.1DHPS-IN-1
CAS :<p>DHPS-IN-1, a chemical compound, demonstrates exceptional inhibitory potency against melanoma cells, as evidenced by its IC50 value of 0.014 μM.</p>Formule :C17H13BrClN3O2Couleur et forme :SolidMasse moléculaire :406.668-Chloroguanosine
CAS :<p>8-Chloroguanosine is a Nucleoside Derivative - Halo-nucleoside, 8-Modified purine nucleoside.</p>Formule :C10H12ClN5O5Couleur et forme :SolidMasse moléculaire :317.69
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