Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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PROTAC IRAK4 degrader-4
CAS :<p>PROTAC IRAK4 degrader-4 is a targeted Cereblon-based molecule for degrading IRAK4.</p>Formule :C41H38F3N11O10Couleur et forme :SolidMasse moléculaire :901.817CAY10614
CAS :<p>CAY10614 is a TLR4 antagonist.</p>Formule :C42H78INO2Couleur et forme :SolidMasse moléculaire :755.995N188 TFA
<p>N188 TFA is a radiolabeled ligand based on a bicyclic peptide scaffold, targeting the protein nectin-4, which is overexpressed in various tumors. It can be efficiently labeled with the radioactive isotope 68Ga to form 68Ga-N188, suitable for positron emission tomography (PET) imaging. The development of N188 TFA and its radiolabeled form, 68Ga-N188, holds potential for the diagnosis and treatment of cancers such as urothelial carcinoma.</p>Couleur et forme :Odour SolidNoraramtide
CAS :<p>Noraramtide (BHV-1100) is an antibody recruiting molecule that specifically binds to the CD38 molecule to recruit natural killer (NK) cells. This interaction enhances the NK cells' ability to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while preventing mutual NK cell destruction. Noraramtide is utilized in research on autologous cancer immunotherapy.</p>Formule :C210H300N48O65S3Couleur et forme :SolidMasse moléculaire :4633.11Moxilubant HCl
CAS :<p>Moxilubant HCl: small molecule LTB4R antagonist for immune, skin, musculoskeletal disorders, and research in psoriasis, arthritis.</p>Formule :C26H38ClN3O4Degré de pureté :99.94%Couleur et forme :SoildMasse moléculaire :492.054-hydroperoxy 2-Nonenal
CAS :<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Formule :C9H16O3Couleur et forme :SolidMasse moléculaire :172.224ROS-IN-1
CAS :<p>ROS-IN-1 is a mitochondrial ROS inhibitor that can be used to reduce oxidative stress or inhibit reactive oxygen species (ROS) production.</p>Formule :C13H17NO3SDegré de pureté :97.53%Couleur et forme :SolidMasse moléculaire :267.34OT-551 HCl
CAS :<p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>Formule :C13H24ClNO3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :277.79BQ0413
CAS :<p>BQ0413 exhibits high affinity for PSMA, with a dissociation constant (KD) of 89 pM. It demonstrates effective uptake and internalization, with an internalization rate of 44% in PC3-pip cells. After being labeled with [99mTc], BQ0413 can serve as an imaging agent for tumors.</p>Formule :C69H96N12O24SCouleur et forme :SolidMasse moléculaire :1509.63PSMA-ALB-56
CAS :<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Formule :C66H95N11O18Couleur et forme :SolidMasse moléculaire :1330.52Spirohexenolide A
CAS :<p>Spirohexenolide A is an inhibitor of human macrophage migration inhibitory factor (hMIF) with a dissociation constant (Kd) of 35.9 μM. It is employed in the study of cellular transport.</p>Couleur et forme :SolidTomaralimab
CAS :<p>Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS).</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :145.32 kDaPSB-12379 disodium
<p>PSB-12379 disodium is a nucleotide analogue acting as a potent inhibitor of Ecto-5'-Nucleotidase (CD73), demonstrating inhibitory constants (Ki) of 9.03 nM in</p>Formule :C18H21N5Na2O9P2Couleur et forme :SolidMasse moléculaire :559.31Keap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Couleur et forme :Odour SolidKD014
<p>KD014 (DX-2400) is a human monoclonal antibody (mAb) that targets MMP14, with a Ki of 0.9 nM. It inhibits TGFβ and SMAD2/3 signaling, increases macrophage count and iNOS expression, and shifts macrophage phenotype towards an antitumor M1-like type. KD014 exhibits antitumor activity in three tumor models (MDA-MB-231, MDA-MB-435, and PC3) and is applicable in breast cancer research.</p>Couleur et forme :Odour LiquidTorudokimab
<p>Torudokimab (ZB-880) is a monoclonal antibody that neutralizes interleukin 33 and can be used to study immune system diseases.</p>Degré de pureté :95.8% (SDS-PAGE); 96.2% (SEC-HPLC) - 95.8% (SDS-PAGE); 96.2% (SEC-HPLC)Couleur et forme :Odour LiquidSARS-CoV-2 Mpro-IN-41
<p>SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.</p>Formule :C27H23ClN4O3SCouleur et forme :SolidMasse moléculaire :518.11794TLR8 agonist 2 hydrochloride
CAS :<p>TLR8 agonist 2 hydrochloride: potent for human TLR8 (EC50 3 nM), weak for TLR7 (EC50 33.33 μM).</p>Formule :C16H22N8·xHClCouleur et forme :SolidEC1169
CAS :<p>EC1169 is a targeted PSMA ligand that acts to inhibit the proliferation of cells expressing PSMA.</p>Formule :C78H112N14O28S3Couleur et forme :SolidMasse moléculaire :1790.00Anticonvulsant agent 10
<p>Anticonvulsant agent 10 (Compound 6d) is an inhibitor targeting the Keap1-Nrf2 interaction, with a strong activity showing an ED50 of 0.04 mmol/kg. By inhibiting the Keap1-Nrf2 binding, it activates the Nrf2/ARE pathway, providing anticonvulsant and neuroprotective effects, making it useful for research in epilepsy and neuroprotection.</p>Couleur et forme :Odour SolidRH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Formule :C28H25N3O4Couleur et forme :SolidMasse moléculaire :467.52Inbakicept
CAS :<p>Inbakicept (ALT 803) is a fusion protein of the IL-15 receptor 伪-sushi binding domain IL-15R伪Su and immunoglobulin G1 (human Fc fragment).</p>Degré de pureté :98.94%Couleur et forme :LiquidKeap1/Nrf2/ARE activator 1
<p>Keap1/Nrf2/ARE activator 1 (compound HT-3) functions as an activator of the Keap1/Nrf2/ARE pathway. This compound has antioxidant properties and offers neuroprotective effects.</p>Formule :C19H20O6Couleur et forme :SolidMasse moléculaire :344.12599Perfluorododecanoic acid
CAS :<p>Perfluorododecanoic acid (PFDoA) is a PFAS pollutant causing ROS increase, mitochondrial damage, and neuronal cytotoxicity.</p>Formule :C12HF23O2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :614.1Tempone
CAS :<p>Tempone, an aminooxyalkane, scavenges free radicals and lowers arterial pressure in hypertensive rats.</p>Formule :C9H16NO2Degré de pureté :98.18%Couleur et forme :Dark Red Munsell 10 R 3/6 LiquidMasse moléculaire :170.23Prifelone
CAS :<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Formule :C19H24O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :316.464-ACETAMIDOANTIPYRINE
CAS :<p>4-ACETAMIDOANTIPYRINE, with CAS No. 83-15-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 4-ACETAMIDOANTIPYRINE provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C13H15N3O2Couleur et forme :SolidMasse moléculaire :245.28Clazakizumab
CAS :<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Couleur et forme :LiquidAc-LDEETGEFL-NH2
CAS :<p>Ac-LDEETGEFL-NH2 is a fluorescent molecule designed to target the interaction between the Kelch-like ECH-associated protein 1 (Keap1) and nuclear factor</p>Formule :C48H72N10O19Couleur et forme :SolidMasse moléculaire :1093.14GHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Formule :C41H56N2O14Couleur et forme :SolidMasse moléculaire :800.89AM-103 Free Acid
CAS :<p>AM-103 Free Acid is a bio-active chemical.</p>Formule :C36H39N3O4SCouleur et forme :SolidMasse moléculaire :609.78PSMA-IN-2
CAS :<p>PSMA-IN-2, an inhibitor of PSMA with a K i value of 1.07 nM, exhibits favorable in vivo NIR imaging (λ EM = 1088 nm, λ ex = 808 nm) and is useful for NIRII image-guided tumor resection surgery in PSMA-positive tumor-bearing mice [1].</p>Formule :C54H60N14O18S2Couleur et forme :SolidMasse moléculaire :1257.27STING agonist-28
CAS :<p>STING agonist-28 (CF510), a non-nucleotide, boosts STING, TBK1, IRF3 phosphorylation, and cytokines; active against SARS-CoV.</p>Formule :C39H46N14O6Couleur et forme :SolidMasse moléculaire :806.87IFN-γ Antagonist 1 acetate
<p>IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate, an interferon γ (IFN γ) antagonist, effectively inhibits the expression of HLR/DR antigen in Colon 205</p>Formule :C117H198N34O36SCouleur et forme :SolidMasse moléculaire :2689.1N(G)-Nitroarginine-4-nitroanilide
CAS :<p>N(G)-Nitroarginine-4-nitroanilide is an anti-nociceptive in mice.</p>Formule :C12H17N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.31Anti-inflammatory agent 38
<p>Compound 23d, an Nrf2/HO-1 inhibitor, with IC50 of 0.38 μM for NO, reduces cellular ROS for anti-inflammatory research.</p>Formule :C36H46N2O13SCouleur et forme :SolidMasse moléculaire :746.82AB-680 ammonium
<p>AB-680: potent, reversible CD73 inhibitor, Ki=4.9 pM, >10,000-fold selectivity vs CD39, anti-tumor.</p>Formule :C20H30ClFN6O9P2Couleur et forme :SolidMasse moléculaire :614.89Anti-inflammatory agent 36
CAS :<p>Anti-inflammatory compound inhibits TNF-a/IL-6 in mouse macrophages; IC50=3.69/3.68uM.</p>Formule :C25H27NO7Degré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :453.48PU23
CAS :<p>PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).</p>Formule :C21H19N3O3S2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :425.52IFN-γ Antagonist 1
CAS :<p>IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells</p>Formule :C115H194N34O34SCouleur et forme :SolidMasse moléculaire :2629.04Mifamurtide
CAS :<p>Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects.</p>Formule :C59H109N6O19PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1237.5IACS-8803 diammonium
<p>IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].</p>Formule :C20H29FN12O9P2S2Couleur et forme :SolidMasse moléculaire :726.6Varokibart
CAS :<p>Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].</p>Couleur et forme :LiquidDA-E 5090
CAS :<p>DA-E 5090, an active metabolite of E 5090, inhibits IL-1 production in human monocytes.</p>Formule :C17H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.32Pegaldesleukin
CAS :<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Couleur et forme :LiquidCannabigerolic acid
CAS :<p>Cannabigerolic acid has antiviral activity and inhibits the TRPM7 ion channel, and is used in the study of acute respiratory syndrome.</p>Formule :C22H32O4Couleur et forme :SolidMasse moléculaire :360.49NLRP3-IN-63
CAS :<p>NLRP3-IN-63 (Compound 7) is an inhibitor of NLRP3, effectively suppressing NLRP3 activation with an EC50 of 13 nM.</p>Formule :C20H22F3N5OCouleur et forme :SolidMasse moléculaire :405.42FITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour SolidBMX-010
CAS :<p>BMX-010, also known as AEOL-10113, is Porphyrin-Based SOD Mimic.</p>Formule :C48H44Cl5MnN8Couleur et forme :SolidMasse moléculaire :965.12Anti-MRC2/CD280 Antibody
<p>Anti-MRC2/CD280 Antibody is a humanized anti-MRC2/CD280 antibody that can be used in immunoblotting (WB) and immunohistochemistry experiments.</p>Degré de pureté :99.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 99.1% (SDS-PAGE); 98.7% (SEC-HPLC)Couleur et forme :Odour LiquidCDD-3290
<p>CDD-3290 (Compound 20) is an inhibitor of prostate-specific antigen (PSA) with a Ki value of 216 nM. This compound also exhibits inhibitory effects on α-chymotrypsin and elastase.</p>Couleur et forme :Odour SolidZ-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Formule :C33H50F4N10O8Couleur et forme :SolidMasse moléculaire :790.81TLR7/8 agonist 4 TFA
CAS :<p>TLR7/8 agonist 4 TFA (compound 41) is a highly potent TLR7/8 agonist that exhibits significant anti-cancer activity.</p>Formule :C20H25F3N6O2Couleur et forme :SolidMasse moléculaire :438.45RDR 02308
CAS :<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Formule :C19H15N3O3Couleur et forme :SolidMasse moléculaire :333.34Dectrekumab
CAS :<p>Dectrekumab (QAX576) is a humanized monoclonal antibody targeting IL-13.</p>Degré de pureté :96.5% (SDS-PAGE); 97.1% (SEC-HPLC) - 96.5% (SDS-PAGE); 97.1% (SEC-HPLC)Couleur et forme :LiquidTP508
CAS :<p>TP508 (Chrysalin), a 23-amino-acid peptide from human prothrombin, aids in tissue repair, targeting thrombin receptors.</p>Formule :C97H146N28O36SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2312.44IKKγ NBD Inhibitory Peptide
CAS :<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Formule :C170H259N49O42S1Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3693.3Vemircopan
CAS :<p>Vemircopan is a complement factor D inhibitor.</p>Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493NC318
<p>NC318 is a humanized antibody targeting Siglec-15/CD33L3 for the study of non-small cell lung cancer.</p>Degré de pureté :98.6% (SDS-PAGE); 99% (SEC-HPLC) - 98.6% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :Odour LiquidDamnacanthol
<p>Damnacanthol is a useful organic compound for research related to life sciences and the catalog number is T131609.</p>Formule :C16H12O5Couleur et forme :SolidMasse moléculaire :284.267cyclo(RLsKDK) TFA
<p>Cyclo(RLsKDK) TFA (BK-1361 TFA) is a cyclic peptide and selective ADAM8 metalloproteinase inhibitor, used in research on inflammation and cancer.</p>Formule :C33H58F3N11O11Degré de pureté :98.54%Couleur et forme :SolidMasse moléculaire :841.88TBK1/IKKε-IN-6
CAS :<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formule :C31H36F2N8O4Couleur et forme :SolidMasse moléculaire :622.678DOPAL
CAS :<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Formule :C8H8O3Couleur et forme :SolidMasse moléculaire :152.15MAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Couleur et forme :Odour SolidFITC-labeled Agatolimod sodium
<p>FITC-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour SolidChitoheptaose heptahydrochloride
CAS :<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formule :C42H80ClN7O29Couleur et forme :SolidMasse moléculaire :1182.57HuMax-IL8
<p>HuMax-IL8 (MDX 018) is a humanized anti-IL-8 monoclonal antibody for the study of metastatic or unresectable solid tumors.</p>Degré de pureté :98.8% (SDS-PAGE); 97.4% (SEC-HPLC) - 98.8% (SDS-PAGE); 97.4% (SEC-HPLC)Couleur et forme :Odour LiquidEfmarodocokin alfa
CAS :<p>Efmarodocokin alfa, IL-22/IgG4 fusion protein, activates IL-22 pathways, researched for severe COVID-19 pneumonia.</p>Couleur et forme :LiquidIFN-α Receptor Recognition Peptide 1
CAS :<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formule :C35H59N13O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :885.99Septeremophilane E
<p>Septeremophilane E, from Septoria rudbeckiae fungus, inhibits NO production.</p>Formule :C21H26O5Couleur et forme :SolidMasse moléculaire :358.43ROS inducer 6
<p>ROS inducer 6 (compound 9) acts as a reactive oxygen species (ROS) inducer by depleting intracellular glutathione, thereby functioning as an antitumor agent.</p>Formule :C32H26N2O3Couleur et forme :SolidMasse moléculaire :486.56Neuroprotective agent 8
<p>Neuroprotective agent 8 (compound AA-9) is an orally active neuroprotective agent that functions through antioxidant stress reduction and anti-inflammatory mechanisms. In a rat model of MCAO ischemic stroke, it activates PGC-1α and inhibits the NLRP3 inflammasome.</p>Couleur et forme :Odour Solid17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS :<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495WAY-605471
CAS :<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formule :C14H15NO3S2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :309.4ODN 2395
CAS :<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Couleur et forme :SolidMasse moléculaire :7035RC529-MDP
<p>RC529-MDP is an immunological adjuvant that couples Toll-like receptors (TLR4a) and NOD-like receptors (NOD2a) to enhance the innate immune response through the TLR4 and NOD2 signaling pathways. In mouse models, RC529-MDP induces high levels of the cytokine interleukin-related factor (IL-6), highlighting its immunostimulatory activity. Additionally, when injected into mice models with ovalbumin (OVA), RC529-MDP elevates OVA-specific antibody responses, T cell responses, and the proportion of memory T cells.</p>Formule :C118H215N10O28PCouleur et forme :SolidMasse moléculaire :2252.99JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Formule :C45H73N3O13Couleur et forme :SolidMasse moléculaire :864.073Ripertamab
CAS :<p>Ripertamab (SCT-400) is a recombinant human-mouse chimeric monoclonal antibody that targets CD20 and is cytotoxic.</p>Degré de pureté :97.8% (SEC-HPLC) - 97.8% (SEC-HPLC)Couleur et forme :Liquid3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formule :C30H44O7SCouleur et forme :SolidMasse moléculaire :548.73Biotinoyl tripeptide-1
CAS :<p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>Formule :C24H38N8O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :566.67Bavunalimab
CAS :<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Couleur et forme :LiquidLadanetin-6-O-β-D-glucopyranoside
CAS :<p>Ladanetin-6-O-β-D-glucopyranoside, an active flavonoid, exhibits antioxidative effects and has potential for research into cardioprotective effects [1].</p>Formule :C22H22O11Couleur et forme :SolidMasse moléculaire :462.4SARS-CoV-2-IN-107
<p>SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.</p>Formule :C15H11FO4Couleur et forme :SolidMasse moléculaire :274.244IL-17A inhibitor 2
CAS :<p>IL-17A inhibitor 2 is an IL-17A inhibitor for treating psoriasis, rheumatoid arthritis, and multiple sclerosis.</p>Formule :C24H25F7N8O4Couleur et forme :SolidMasse moléculaire :622.505CAY10512
CAS :<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formule :C15H13FOCouleur et forme :SolidMasse moléculaire :228.266Romilkimab
CAS :<p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>Couleur et forme :LiquidCLIP (86-100)
CAS :<p>Amino acids 86-100 of CLIP, replaced by DM to allow MHC class II to present foreign peptides, triggering immune response.</p>Formule :C72H128N20O19S3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1674.1Factor B-IN-1
CAS :<p>Factor B-IN-1 is a Factor B inhibitor.</p>Formule :C19H16N4O2Couleur et forme :SolidMasse moléculaire :332.3559PROTAC IRAK4 degrader-5
CAS :<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formule :C41H40F3N11O9Couleur et forme :SolidMasse moléculaire :887.834Mifamurtide sodium
CAS :<p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>Formule :C59H108N6NaO19PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1259.48KTX-955
CAS :<p>KTX-955, a potent IRAK4 degrader, exhibits DC50 values of 5 nM for IRAK4 and 130 nM for Ikaros. It is primarily utilized in anticancer research [1] [2].</p>Formule :C46H51F3N8O7Couleur et forme :SolidMasse moléculaire :884.94STING agonist-17
CAS :<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formule :C43H53N13O8Couleur et forme :SolidMasse moléculaire :879.96MCC950
CAS :<p>MCC950 (CP-456773) is a NLRP3 inflammasome inhibitor (IC50=7.5-8.1 nM). MCC950 can be used to treat inflammatory diseases. High-Quality, Low-Cost!</p>Formule :C20H24N2O5SDegré de pureté :97% - 98%Couleur et forme :SolidMasse moléculaire :404.48CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Couleur et forme :SolidNosantine racemate
CAS :<p>Nosantine racemate is the racemate of Nosantine which is a IL-2 inducer or enhancer of IL-2 induction by phytohemagglutinin (PHA).</p>Formule :C14H22N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :278.35Nω-Propyl-L-arginine
CAS :<p>Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM.</p>Formule :C9H20N4O2Couleur et forme :SolidMasse moléculaire :216.28Bivalirudin TFA
CAS :<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Formule :C98H138N24O33·C2HF3O2Couleur et forme :SolidMasse moléculaire :2294.34G3-C12
CAS :<p>G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.</p>Formule :C74H115N23O23S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1758.99PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06Bengamide B
CAS :<p>Potent NF-κB inhibitor, IC50 at 85 nM. Reduces IκBα phosphorylation, NO, TNF-α, IL-6, MCP. Inhibits HeLa, HCT116 cell growth. Anti-inflammatory, antitumor.</p>Formule :C32H58N2O8Couleur et forme :SolidMasse moléculaire :598.81
