Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(148 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(112 produits)
- IκB/IKK(60 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(444 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3034 produits trouvés pour "Immunologie et Inflammation"
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BMS-378806
CAS :BMS-378806 (BMS-806) selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in virus.Formule :C22H22N4O4Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :406.43AZD4144
CAS :<p>AZD4144 is a potent and selective NLRP3 inhibitor (IC50 = 54 nM) that reducs IL-1β and IL-18 production for immune disorders.</p>Formule :C18H16F3N3O3Degré de pureté :99.02%Couleur et forme :SoildMasse moléculaire :379.333,4-DAA
CAS :<p>3,4-DAA has anti-inflammatory activity and inhibits EOC20 cell-induced nitric oxide synthase (iNOS) induced by IFN-γ and lipopolysaccharide.</p>Formule :C18H17NO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :343.33(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one
CAS :(9α,13α,14α)-4-Hydroxy-3,7-dimethoxy-7,8-didehydromorphinan-6-one is a major mechanism of Sinomenine.Formule :C18H21NO4Degré de pureté :97.85%Couleur et forme :SoildMasse moléculaire :315.36AHR-10037
CAS :<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Formule :C15H13ClN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :288.73E3330
CAS :<p>E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.</p>Formule :C21H30O6Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :378.46Allopurinol Sodium
CAS :<p>Allopurinol Sodium is a xanthine oxidase inhibitor with an IC50 of 7.82±0.12 μM.</p>Formule :C5H4N4NaODegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :159.1Pelubiprofen
CAS :<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Formule :C16H18O3Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :258.31Catalase
CAS :<p>Catalase, an enzyme, metabolizes H2O2 and ROS; its expression and localization change significantly in tumors.</p>Degré de pureté :≥98%Couleur et forme :Small Colorless Crystals Or Powder At Room Temperature Almost Odourless Small Colourless Crystals Or A White Crystalline PowderiNOs-IN-3
CAS :<p>iNOs-IN-3: oral iNOS inhibitor, IC50 = 3.342 μM, anti-inflammatory, for LPS-induced ALI study.</p>Formule :C27H24N2O5SCouleur et forme :SolidMasse moléculaire :488.55TNF-α-IN-18
CAS :<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Formule :C16H7ClF2O4Degré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :336.67COX-2-IN-22
CAS :<p>COX-2-IN-22 inhibits COX-2 (IC50: 8.6μM) and crosses the blood-brain barrier, also affects AChE, BChE, β-Secretase, LOX-5, DPPH.</p>Formule :C29H24O7Couleur et forme :SolidMasse moléculaire :484.5Fc 11a-2
CAS :<p>Fc 11a-2, an oral benzimidazole, potently inhibits NLRP3 inflammasome and caspase-1 to prevent colitis.</p>Formule :C16H16N2Couleur et forme :SolidMasse moléculaire :236.31Anti-inflammatory agent 21
CAS :<p>Compound 9o: orally active, low-toxicity anti-inflammatory; inhibits NO (IC50: 0.76 μM), blocks NF-κB/MAPK, reduces arthritis symptoms.</p>Formule :C24H21FO6Couleur et forme :SolidMasse moléculaire :424.42STING Agonist C11
CAS :<p>STING agonist C11 activates STING, induces type I IFN in cells, phosphorylates IRF3, and lowers various viral titers via STING/IFNAR pathway.</p>Formule :C19H18N4O3SCouleur et forme :SolidMasse moléculaire :382.44Carboxyamidotriazole
CAS :<p>Carboxyamidotriazole is a cytostatic inhibitor of non-voltage-operated calcium channels and calcium channel-mediated signaling pathways.</p>Formule :C17H12Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.67BCX 1470
CAS :<p>BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.</p>Formule :C14H10N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :302.37HSR1304
CAS :<p>HSR1304 (5d) inhibits NFκB, key in diseases like cancer, offering research potential.</p>Formule :C24H21ClN2O3Couleur et forme :SolidMasse moléculaire :420.89AP-1/NF-κB activation inhibitor 1
CAS :<p>AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basal</p>Formule :C13H11F3N4O4Degré de pureté :99.52% - 99.91%Couleur et forme :SolidMasse moléculaire :344.25U-83836E
CAS :<p>U-83836E (lazaroid ) Possesses neuroprotective activity and anti-tumor activity, inhibits tumor necrosis factor and reverses endotoxin-induced shock.</p>Formule :C30H46Cl2N6O2Degré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :593.63COX-2-IN-28
CAS :<p>COX-2-IN-28 is a potent and selective COX-2 inhibitor capable of acting on COX-2 (IC50: 0.054 μM), 15-LOX (IC50: 2.14 μM) and COX-1 (IC50: 13.21 μM).</p>Formule :C30H27N7S3Couleur et forme :SolidMasse moléculaire :581.78CK-119
CAS :<p>CK-119 inhibits IL-1, blocking corneal/conjunctival cell growth by halting DNA/RNA synthesis.</p>Formule :C21H23ClN4O5Couleur et forme :SolidMasse moléculaire :446.88MIP-1095
CAS :<p>MIP-1095 is the prostate-specific membrane antigen inhibitor.</p>Formule :C19H25IN4O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :564.33MIF-IN-3
CAS :<p>MIF-IN-3 inhibits MIF; useful in immunoinflammation research. (WO2021258272A1, compound 31)</p>Formule :C20H20N4O5SCouleur et forme :SolidMasse moléculaire :428.46BBS-4
CAS :<p>BBS-4 inhibits NOS2 dimerization (IC50: 0.49 nM), guarding mice against sepsis-related heart issues.</p>Formule :C22H24N6O3Couleur et forme :SolidMasse moléculaire :420.46Naproxcinod
CAS :<p>Naproxcinod is a derivative of naproxen, analgesic and anti-inflammatory, a COX-inhibitory nitric oxide donor (CINOD), osteoarthritis and inflammatory.</p>Formule :C18H21NO6Couleur et forme :SolidMasse moléculaire :347.36NOC-5
CAS :<p>NOC-5 is an NO donor that induces airway relaxation and concentration-dependently triggers 10 μM DAF-2 fluorescence.</p>Formule :C6H16N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :176.22NIC-0102
CAS :<p>NIC-0102 is an orally active proteasome inhibitor (pIC50:7.55) that exhibits specific inhibition of NLRP3 inflammatory vesicle activation. Inhibitory effect.</p>Formule :C21H25BF2N2O4Couleur et forme :SolidMasse moléculaire :418.24NBC 19
CAS :<p>Potent NLRP3 inflammasome inhibitor (IC50 = 60-80 nM). Inhibits nigericin- and ATP-induced IL-1β release.</p>Formule :C24H26BCl3N2O2Couleur et forme :SolidMasse moléculaire :491.65Stigmane B
<p>Stigmane B activates Nrf2, decreases apoptosis and ROS, boosts antioxidants, and is neuroprotective.</p>Formule :C21H30O4Couleur et forme :SolidMasse moléculaire :346.46Dibenzo(a,i)pyrene
CAS :<p>Dibenzo(a, i)pyrene is a polycyclic aromatic hydrocarbon with potent carcinogenic activity.</p>Formule :C24H14Couleur et forme :Greenish-Yellow Needles Prisms Or Lamellae Dibenz[A I]Pyrene Is A Colorless Solid Water InsolubleMasse moléculaire :302.37Leptospermone
CAS :<p>Leptospermone is an essential oil from Leptospermum scoparium (manuka oil).</p>Formule :C15H22O4Couleur et forme :SolidMasse moléculaire :266.33NOS1-IN-1
CAS :<p>NOS1-IN-1: selective, potent nNOS inhibitor (Ki: 120 nM), less effective on eNOS/iNOS, for neurological disorder research.</p>Formule :C14H24F9N7O8Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :589.37Nexinhib20
CAS :<p>Nexinhib20 is an inhibitor of exosome synthesis and transport with anti-inflammatory activity, inhibits RAB27A and neutral sphingomyelinase 2 (nSMase2) nsMase2.</p>Formule :C15H16N4O3Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :300.31FK-330 dihydrate
CAS :<p>FK-330 dihydrate (FR-260330 dihydrate), as a NOS inhibitor, prevents tissue damage caused by ischemia and reperfusion. Cost-effective and quality-assured.</p>Formule :C29H32ClF3N6O6Degré de pureté :99.52% - 99.98%Couleur et forme :SolidMasse moléculaire :653.05Feprazone
CAS :<p>Feprazone (DA-2370) possesses anti-inflammatory and antiadipogenic properties. Feprazone can be used in studies about the treatment of joint and muscular pain.</p>Formule :C20H20N2O2Degré de pureté :99.6% - 99.89%Couleur et forme :SolidMasse moléculaire :320.3912(R)-HETE
CAS :<p>12(R)-HETE made in invertebrates by lipoxygenation, in mammals by 12(R)-LOs/CYP450. Mainly proinflammatory, attracts leukocytes, reduces rabbit eye pressure.</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47DPP-4 inhibitor 3
CAS :<p>DPP-4 inhibitor 3 is a powerful DPP-IV blocker with 0.75 nM IC50, boasting antioxidant and insulinotropic effects.</p>Formule :C19H22N6O2Couleur et forme :SolidMasse moléculaire :366.42Imupedone
CAS :<p>Imupedone (LF 1695) is a synthetic immunomodulator that increases the proliferative response of lymphocytes to mitogens, antigens and allogeneic cells.</p>Formule :C19H21ClN2ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :328.84CID-2858522
CAS :<p>CID-2858522 is an effective and specific antigen receptor-mediated NF-κB activation inhibitor (IC50: 70 nM).</p>Formule :C28H39N3O3Degré de pureté :96.12%Couleur et forme :SolidMasse moléculaire :465.63Galectin-3-IN-1
CAS :<p>Galectin-3-IN-1 is a potent Gal-3 inhibitor, key in cancer-related metabolic processes.</p>Formule :C18H26O10SCouleur et forme :SolidMasse moléculaire :434.46Naproxen glucuronide
CAS :<p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>Formule :C20H22O9Couleur et forme :SolidMasse moléculaire :406.38CHD-5
CAS :<p>CHD-5 is a selective antagonist of the aryl hydrocarbon receptor (AhR).</p>Formule :C19H17N3O2Couleur et forme :SolidMasse moléculaire :319.36IRAK4-IN-22
CAS :<p>IRAK4-IN-22: oral IRAK4 inhibitor, IC50: IRAK4-3nM, TAK1-17nM, disrupts IL-23, targets autoimmune diseases.</p>Formule :C28H28FN7O2Couleur et forme :SolidMasse moléculaire :513.57Enflicoxib
CAS :<p>Enflicoxib is an effective treatment for canine osteoarthritis pain and inflammation, with faster onset than mavacoxib, improving veterinary outcomes.</p>Formule :C16H12F5N3O2SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :405.34Ro 106-9920
CAS :<p>Inhibitor of NF-κB activation</p>Formule :C10H7N5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :245.26Tilarginine citrate
CAS :<p>Tilarginine citrate is a competitive nitric oxide synthetase inhibitor.</p>Formule :C13H24N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :380.354HE 3286
CAS :<p>Triolex, an NF-kB inhibitor, is used potentially for the treatment of rheumatoid arthritis, ulcerative colitis.</p>Formule :C21H30O3Couleur et forme :SolidMasse moléculaire :330.46ROS inducer 3
CAS :<p>ROS inducer 3 is a ROS inducer used as a bactericide in the study of resistant plant bacterial diseases, inhibiting Streptomyces.</p>Formule :C22H22F3N3ODegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :401.43ROS inducer 2
CAS :<p>ROS inducer 2 is a reactive oxygen species (ROS) inducer with antibacterial activity, inhibiting Axonobacter species.</p>Formule :C23H24F3N3ODegré de pureté :99.53% - 99.97%Couleur et forme :SolidMasse moléculaire :415.45COX-2-IN-21
CAS :<p>COX-2-IN-21 (Compound 5c) is an orally active, selective COX-2 inhibitor (IC50: 0.039 μM). COX-2-IN-21 has good anti-inflammatory potential.</p>Formule :C21H22N6O4Couleur et forme :SolidMasse moléculaire :422.44IND24
CAS :<p>IND24 has anti-prion activity and can be used to study neurodegenerative diseases.</p>Formule :C21H17N3SDegré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :343.44NF-κB-IN-3
CAS :<p>NF-κB-IN-3 (Compound 2) is an NF-κB inhibitor (IC50: 0.70 μM) and can be used as an anti-tumour agent.</p>Formule :C24H18ClF3N2O2Couleur et forme :SolidMasse moléculaire :458.86AChE/Nrf2 modulator 1
CAS :<p>AChE/Nrf2 modulator 1: oral, targets AChE/Nrf2, IC50s: 0.07 μM (eeAChE), 0.38 μM (hAChE); for Alzheimer's research.</p>Formule :C27H27FN4O2Couleur et forme :SolidMasse moléculaire :458.53Ferric citrate
CAS :<p>Ferric citrate as a source of iron used in cell culture applications can provide iron with a less toxic form compared to free iron salts.</p>Formule :C6H8FeO7Couleur et forme :Limit Its Spread To The Environment It Is Used In Medicine In Making Blueprints And As A FeedMasse moléculaire :247.968Nrf2 activator-5
CAS :<p>Nrf2 activator-5 combats oxidative stress and inflammation in microglia, with potent antioxidant effects.</p>Formule :C25H30Cl2O6Couleur et forme :SolidMasse moléculaire :497.41Antimicrobial agent-2
CAS :<p>Compound V-a: broad-spectrum, low-toxicity antimicrobial with no resistance, high bioavailability, damages membranes, targets MRSA (MIC 1μg/mL).</p>Formule :C16H14N2O4SCouleur et forme :SolidMasse moléculaire :330.36Ophthalmic acid
CAS :<p>Ophthalmic acid is a glutathione analog in which cysteine is substituted by L-aminobutyrate.</p>Formule :C11H19N3O6Couleur et forme :SolidMasse moléculaire :289.29Keap1-Nrf2-IN-11
CAS :<p>Keap1-Nrf2-IN-11 (6k) inhibits Keap1-Nrf2, KD 0.21 nM; reduces ROS, NO, TNF-α; aids anti-inflammatory research.</p>Formule :C36H43N7O8S2Couleur et forme :SolidMasse moléculaire :765.910-Cl-BBQ
CAS :<p>10-Cl-BBQ is a ligand of aryl hydrocarbon receptor (AhR).</p>Formule :C18H9ClN2OCouleur et forme :SolidMasse moléculaire :304.73Antiviral agent 14
CAS :<p>Antiviral agent 14 is an antiviral agent that inhibits tobacco mosaic virus (TMV) (EC50: 135.5 μg/mL), and cucumber mosaic virus (CMV) (EC50: 178.6 μg/mL).</p>Formule :C24H26O7Couleur et forme :SolidMasse moléculaire :426.46NXPZ-2
CAS :<p>NXPZ-2, an oral Keap1-Nrf2 PPI inhibitor (Ki: 95 nM, EC50: 120-170 nM), may improve cognition and neuron health in AD.</p>Formule :C27H27N5O7S2Couleur et forme :SolidMasse moléculaire :597.66APHS
CAS :<p>APHS is a cyclooxygenase-2 (COX-2) inhibitor with anti-inflammatory action. It also more potent than aspirin in the inhibition of COX-1.</p>Formule :C15H18O2SCouleur et forme :SolidMasse moléculaire :262.37S-Isopropylisothiourea hydrobromide
CAS :<p>S-Isopropylisothiourea hydrobromide is an iNOS inhibitor.</p>Formule :C4H11BrN2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :199.11Keap1-Nrf2-IN-12
CAS :<p>eap1-Nrf2-IN-12 is a potent inhibitor of Keap1-Nrf2 (IC50: 2.30 μM). eap1-Nrf2-IN-12 is metabolically stable in human liver microsomes.</p>Formule :C26H28N2O10S2Couleur et forme :SolidMasse moléculaire :592.64Piroxicam cinnamate
CAS :<p>Cinnoxicam is a COX inhibitor used for bone/joint inflammation, rheumatic issues, and varicocele-related oligospermia.</p>Formule :C24H19N3O5SCouleur et forme :SolidMasse moléculaire :461.49IT-901
CAS :<p>IT-901: Oral NF-κB c-Rel inhibitor, IC50 0.1 µM. Blocks c-Rel/DNA binding, IC50 3 µM. Antitumor naphthalene derivative for lymphoma/myeloma therapy.</p>Formule :C17H14N2O4SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :342.37P2X7-IN-2
CAS :<p>P2X7-IN-2 is a P2X7 receptor blocker, halts IL-Iβ release (IC50: 0.01 nM), researched for autoimmunity and heart issues.</p>Formule :C22H21F4N3O2Couleur et forme :SolidMasse moléculaire :435.41PT4
CAS :<p>PT4: treats CL, disrupts parasite mitochondria, kills Leishmania spp., IC50- L. amazonensis 125.18 μM, L. braziliensis 233.18 μM, anti-inflammatory.</p>Formule :C18H14N4O2Couleur et forme :SolidMasse moléculaire :318.33COX-2/5-LOX-IN-2
CAS :<p>COX-2/5-LOX-IN-2, a benzothiophen derivative, inhibits COX-1, COX-2, 5-LOX with IC50s of 5.40, 0.01, 1.78 μM. More effective than Celecoxib, Indomethacin.</p>Formule :C18H13N3O4S2Couleur et forme :SolidMasse moléculaire :399.44DMX-129
CAS :<p>DMX-129 is a chemical compound acting as an inhibitor for both ΙΚΚε and TBK-1, demonstrating efficacy with IC50 values of below 30 nM for each [1].</p>Formule :C19H17FN8Couleur et forme :SolidMasse moléculaire :376.39CAY10589
CAS :<p>CAY10589 is an mPGES-1 inhibitor.</p>Formule :C25H28ClN3O2SCouleur et forme :SolidMasse moléculaire :470.03COX-2-IN-19
CAS :<p>COX-2-IN-19, a potent COX-2 inhibitor, IC50 of 1.76 μM, has strong anti-inflammatory effects in vivo.</p>Formule :C18H18N4O2SCouleur et forme :SolidMasse moléculaire :354.43HPN-01
CAS :<p>HPN-01 (IKK inhibitor XII) is an IKK inhibitor that inhibits IKK-α and IKK-ε, prolongs the lifespan of mice, and can be used to study immune disorders.</p>Formule :C19H16ClN3O3SDegré de pureté :98.07% - 98.17%Couleur et forme :SolidMasse moléculaire :401.87RIP2 Kinase Inhibitor 3
CAS :<p>RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2 with an IC50 of 1 nM.</p>Formule :C19H24N4O3SDegré de pureté :99.32% - 99.52%Couleur et forme :SolidMasse moléculaire :388.48RI-962
CAS :<p>RI-962 is a potent and selective inhibitor of RIPK1 that protects cells from necrotic apoptosis by inhibiting RIPK1, RIPK3, and MLKL phosphorylation.</p>Formule :C28H28N6O2Degré de pureté :99.39%Couleur et forme :SoildMasse moléculaire :480.56TLR7/8 agonist 4
CAS :<p>TLR7/8 agonist 4 (compound 41) is a potent agonist of TLR7/8 with anti-cancer activity [1].</p>Formule :C18H24N6Couleur et forme :SolidMasse moléculaire :324.42NF-κB/PON1-IN-1
CAS :<p>NF-κB/PON1-IN-1 (Compound 16) is an NF-κB/PON1 pathway inhibitor with antioxidant activity (IC50: 45.76 μM) and hepatoprotective activity.</p>Formule :C20H16N6O4S2Couleur et forme :SolidMasse moléculaire :468.51COX-2-IN-24
CAS :<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Formule :C24H24BrN5O3S2Couleur et forme :SolidMasse moléculaire :574.51PPM-18
CAS :<p>PPM-18 (NSC 73233), a potent anti-inflammatory, inhibits iNOS and NF-κB binding; also suppresses bladder cancer cell growth.</p>Formule :C17H11NO3Couleur et forme :SolidMasse moléculaire :277.27IRAK4-IN-13
CAS :<p>IRAK4-IN-13 (compound 21) is a potent IRAK4 inhibitor, IC50 0.6 nM, with high HLM clearance at 96 μL/min/mg.</p>Formule :C24H27N9OCouleur et forme :SolidMasse moléculaire :457.53COX-2-IN-23
CAS :<p>COX-2-IN-23 selectively inhibits COX-2 (IC50=0.28μM), weakly affects COX-1 (IC50=20.14μM), and has anti-inflammatory and low ulcerogenic properties.</p>Formule :C24H25N5O3S2Couleur et forme :SolidMasse moléculaire :495.62Asperbisabolane L
<p>Asperbisabolane L, a sesquiterpenoid, combats inflammation by blocking NF-κB signaling and NO in BV-2 cells.</p>Formule :C12H14O3Couleur et forme :SolidMasse moléculaire :206.24IFN α-IFNAR-IN-1
CAS :<p>Nonpeptidic IFN-α/IFNAR blocker, halts MVA-triggered BM-pDC IFN-α response; IC50: 2-8 μM.</p>Formule :C18H17NSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.4COX-1/2-IN-3
CAS :<p>COX-1/2-IN-3 (Compound 7a) is a dual inhibitor of COX-1 and COX-2. COX-1/2-IN-3 has anti-inflammatory activity with low toxicity [1].</p>Formule :C14H8N2O8Couleur et forme :SolidMasse moléculaire :332.22MIF-IN-1
CAS :<p>MIF-IN-1 (compound 14) inhibits MIF, a cytokine linked to diseases, with pIC50 of 6.87.</p>Formule :C15H13N3O5Couleur et forme :SolidMasse moléculaire :315.28Isofezolac
CAS :<p>Isofezolac (LM 22070), a NSAID, inhibits prostaglandin-synthetase, offering powerful anti-inflammatory and antipyretic effects.</p>Formule :C23H18N2O2Couleur et forme :SolidMasse moléculaire :354.4MSU38225
CAS :<p>MSU38225, an Nrf-2 inhibitor, elevates reactive oxygen species (ROS) levels and suppresses the proliferation of human lung cancer cells.</p>Formule :C21H19N3Couleur et forme :SolidMasse moléculaire :313.43-Bromo-7-nitroindazole
CAS :<p>3-Bromo-7-nitroindazole specifically inhibits nNOS, impacting NO synthesis in brain/body.</p>Formule :C7H4BrN3O2Degré de pureté :98.2%Couleur et forme :Yellowish SolidMasse moléculaire :242.03CU-76
CAS :<p>CU-76 inhibits cGAS (IC50 = 0.24 μM) affecting DNA-induced IFN-β production, not RIG-I-MAVS pathway, in THP-1 cells.</p>Formule :C11H8F2IN5O2Couleur et forme :SolidMasse moléculaire :407.11AN3485 Hydrochloride
CAS :<p>AN3485 Hydrochloride is an anti-inflammatory agent and a TLRs inhibitor, reducing ear swelling induced by PMA.</p>Formule :C14H14BCl2NO3Degré de pureté :98.34%Couleur et forme :SolidMasse moléculaire :325.98Oxyphenbutazone monohydrate
CAS :<p>Oxyphenbutazone monohydrate: Phenylbutazone derivative, anti-inflammatory, non-selective COX inhibitor, kills dormant M. tuberculosis.</p>Formule :C19H22N2O4Couleur et forme :SolidMasse moléculaire :342.39Bay 65-1942 free base
CAS :<p>Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.</p>Formule :C22H25N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.45Z-VRPR-FMK
CAS :<p>Z-VRPR-FMK: irreversible MALT1 inhibitor, halts growth/invasion of diffused B-cell lymphoma by blocking NF-κB activation and MMP expression.</p>Formule :C31H49FN10O6Couleur et forme :SolidMasse moléculaire :676.78COX-1/2-IN-1
CAS :<p>"COX-1/2-IN-2: Strong dual inhibitor of COX-1 (IC50 = 13.9 μM) and COX-2 (IC50 = 6.4 μM)."</p>Formule :C15H10BrClN2OCouleur et forme :SolidMasse moléculaire :349.61β-Nor-lapachone
CAS :<p>β-Nor-lapachone is an antibiofilm agent of Candida glabrata.</p>Formule :C14H12O3Couleur et forme :SolidMasse moléculaire :228.24Keap1-Nrf2-IN-14
CAS :<p>Keap1-Nrf2-IN-14, a KEAP1-NRF2 inhibitor (IC50: 75 nM, Kd: 24 nM), boosts NRF2 gene expression, antioxidative and anti-inflammatory response.</p>Formule :C30H29NO8SCouleur et forme :SolidMasse moléculaire :563.62COX-2/sEH-IN-1
CAS :<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Formule :C23H18F3N5O3SCouleur et forme :SolidMasse moléculaire :501.48Veledimex (S enantiomer)
CAS :<p>Veledimex S is the oral S enantiomer of a gene therapy promoter activator and CYP3A4/5 inhibitor.</p>Formule :C27H38N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.6PNRI-299
CAS :<p>PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).</p>Formule :C21H15N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :401.37
