Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(142 produits)
- CXCR(159 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(110 produits)
- IκB/IKK(59 produits)
- LTR(3 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(434 produits)
- NOD(18 produits)
- NOS(61 produits)
- Nrf2(82 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(61 produits)
- TLR(75 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3373 produits trouvés pour "Immunologie et Inflammation"
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E 5090
CAS :E5090 is a novel orally active inhibitor of IL-1 generation. It also has anti-inflammatory properties.Formule :C19H20O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :328.36KBD4466
CAS :KBD4466 is a potent oral inhibitor of TLR7 and TLR8, with IC50 values of 0.9 nM and 2.8 nM, respectively. This compound effectively suppresses the inflammatory cytokines IL-6 and IFN-α. KBD4466 has shown to improve disease progression and increase survival rates in the BXSB/MpJ mouse model of systemic lupus erythematosus (SLE). It is suitable for research into autoimmune diseases.Formule :C24H23F3N6OCouleur et forme :SolidMasse moléculaire :468.47SARM1-IN-5
CAS :SARM1-IN-5 (compound 1-23-a) is an inhibitor of SARM1, useful for researching diseases related to axonal degeneration, including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS).Formule :C18H17FN6OCouleur et forme :SolidMasse moléculaire :352.37Antibacterial agent 259
CAS :Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.Formule :C7H6ClN3O2SCouleur et forme :SolidMasse moléculaire :231.659COX-2/15-LOX-IN-5
CAS :COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-κB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.Formule :C25H21N3O3SCouleur et forme :SolidMasse moléculaire :443.52Refinicopan
CAS :Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM, demonstrating an inhibition activity on rabbit erythrocyte hemolysis with an IC50 of 41 nM. It possesses excellent pharmacokinetic and pharmacodynamic properties.Formule :C29H32N2O3Couleur et forme :SolidMasse moléculaire :456.58hDDAH-1-IN-2 sulfate
hDDAH-1-IN-2: selective oral hDDAH-1 inhibitor with low cell toxicity.Formule :C8H24N4O10S2Couleur et forme :SolidMasse moléculaire :400.43STING agonist-43
CAS :STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41CYP1B1-IN-10
CAS :CYP1B1-IN-10 (Compound 15C) is a highly selective inhibitor of human cytochrome P450 1B1 (hCYP1B1) with an IC50 value of 0.11 μM. It shows promise for use in research focused on hormone-dependent tumors, including breast and ovarian cancers.Formule :C23H18N2Couleur et forme :SolidMasse moléculaire :322.40Factor B-IN-4
CAS :Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.Formule :C27H32N2O4Couleur et forme :SolidMasse moléculaire :448.55COX-2/PI3K-IN-2
COX-2/PI3K-IN-2 (5f): anti-inflammatory & anti-cancer, selectively inhibits COX-2 (Ki=3.02nM), potently blocks PI3K (IC50=2.78nM).Formule :C16H17N5O2Couleur et forme :SolidMasse moléculaire :311.34Antifungal agent 134
CAS :Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.Formule :C18H12F4N2O4Couleur et forme :SolidMasse moléculaire :396.29TrxR-IN-5
TrxR-IN-5 (compound 4f) is an effective inhibitor of thioredoxin reductase (TrxR) with an IC₅₀ of 0.16 μM. anti-proliferative and anti-metastatic.Formule :C26H22O3Couleur et forme :SolidMasse moléculaire :382.46NOTA-FAPI
CAS :NOTA-FAPI is a FAP inhibitor and FAPI-4 analogue used in PET imaging and targeted therapy for FAP-overexpressing pathological conditions.Formule :C36H47F2N9O8Degré de pureté :99.748%Couleur et forme :SolidMasse moléculaire :771.81IL-6-IN-2
CAS :IL-6-IN-2 (Compound 15) is an inhibitor of the interaction between IL-6 and IL-6R proteins. The compound's binding free energy (∆G) is −36.50 kcal/mol. In its binding with IL-6, the contributions from Lys66, Phe74, Gln175, Ser176, and Arg179 are -1.10, -8.68, -6.91, -3.69, and -1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption rates.Formule :C26H24N4O3Couleur et forme :SolidMasse moléculaire :440.49Numidargistat
CAS :CB-1158 is a potent and orally bioavailable inhibitor of arginase (IC50s: 86 and 296 nM for recombinant human arginase 1 and 2).Formule :C11H22BN3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :287.12ABZI
CAS :(S)-2-(1-Ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1-(2-hydroxy-2-phenylethyl)-1H-benzo[d]imidazole-5-carboxamide (compound 4) is a STING agonist containing the crucial amide benzimidazole (ABZI) component. It consistently inhibits the binding of 3 H-cGAMP to STING, with an apparent inhibition constant (IC50) of 14 μM. This compound is applicable in tumor research.Formule :C23H24N6O3Masse moléculaire :432.48Cyazofamid
CAS :Cyazofamid functions as a fungicide by impairing the production of ATP. It inhibits Organic Cation Transporter 3 (OCT3) and OAT1 with IC50 values of 1.54 and 17.3 μM, respectively.Formule :C13H13ClN4O2SCouleur et forme :SolidMasse moléculaire :324.79Z-Val-Val-Nle-diazomethylketone
CAS :Z-Val-Val-Nle-diazomethylketone is an inhibitor of cathepsin S (CATS). It significantly suppresses the upregulation of IFNg-induced MHCII molecules, specifically HLA-DR and Ii-p33/35, while increasing the protein level of Ii-p10. This compound can be utilized for research into skin disorders such as psoriasis, atopic dermatitis, and actinic keratosis.Formule :C25H37N5O5Couleur et forme :SolidMasse moléculaire :487.59AMC-04
CAS :AMC-04 is a protein response (UPR) activator that initiates the UPR pathway via ROS and p38 MAPK signaling, leading to apoptotic cell death. It is used in cancer research [1].Formule :C26H28N2O3Couleur et forme :SolidMasse moléculaire :416.51AS2690168 hydrochloride
CAS :AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.Formule :C17H15Cl2F3N4OCouleur et forme :SolidMasse moléculaire :419.228IRAK1/4/pan-FLT3 Kinase-IN-2
CAS :IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent dual inhibitor of IRAK1/4 and FLT3 with IC50 values of 10 nM, 0.7 nM, and < 0.5 nM, respectively. This compound enhances survival in mice models of acute myeloid leukemia.Formule :C20H22F3N5OCouleur et forme :SolidMasse moléculaire :405.42IRAK4-IN-31
CAS :IRAK4-IN-31 is a crystalline inhibitor of IRAK4. It is applicable in research related to myelodysplastic syndromes (MDS).Formule :C27H33N5O5Couleur et forme :SolidMasse moléculaire :507.58DEG-35
CAS :DEG-35 is a CRBN-dependent bifunctional degrader targeting IKZF2 and CK1α, with DC50 values of 1.4 nM and 4.4 nM for CK1α and IKZF2, respectively. It activates the p53 apoptotic pathway and is applicable for research related to acute myeloid leukemia (AML).Formule :C25H21N3O5Couleur et forme :SolidMasse moléculaire :443.45a15:0-i15:0 PE
CAS :a15:0-i15:0 PE is a dia-cyl phosphatidylethanolamine with two branched chains. It functions as an atypical TLR2-TLR1 heterodimer agonist and is immunogenic. This compound activates T cell and dendritic cell (DC) signaling, exhibiting anti-inflammatory properties. Additionally, a15:0-i15:0 PE induces the production of TNFα and IL-6. It is a major component of the A. muciniphila lipid membrane, constituting approximately 50%.Formule :C35H70NO8PCouleur et forme :SolidMasse moléculaire :663.91COX-2-IN-7
COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.Formule :C15H13N3O2S2Couleur et forme :SolidMasse moléculaire :331.41TBK1/IKKε-IN-1
CAS :TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).Formule :C28H26N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :498.53MIF2-IN-1
MIF2-IN-1, potent inhibitor of MIF2 (IC50: 1μM), halts non-small cell lung cancer growth via MAPK pathway.Formule :C26H19F3N2O2SCouleur et forme :SolidMasse moléculaire :480.5IRAK4 modulator-1
CAS :IRAK4 Modulator-1 (example 161), an IRAK4 modulator with an IC50 of 4.647 μM, is employed in the investigation of IRAK-mediated disorders [1].Formule :C19H13ClN4O2Couleur et forme :SolidMasse moléculaire :364.79meso-Zeaxanthin
CAS :meso-Zeaxanthin accumulates in the central retina and, together with lutein and zeaxanthin, forms the macular pigment, which functions as a light filter. meso-Zeaxanthin can quench reactive oxygen species (ROS), thereby exhibiting antioxidant properties.Formule :C40H56O2Couleur et forme :SolidMasse moléculaire :568.871IKZF1-degrader-2
CAS :IKZF1-degrader-2 (Compound 3), an IKZF1 degrader, exhibits anticancer activity and low toxicity [1].Formule :C33H30FN5O5Couleur et forme :SolidMasse moléculaire :595.62Dazostinag disodium
CAS :<p>Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.</p>Formule :C21H20F2N8Na2O10P2S2Degré de pureté :98.84% - 99.96%Couleur et forme :SolidMasse moléculaire :754.48Antiproliferative agent-22
CAS :Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.Formule :C17H13N3O3Degré de pureté :99.20% - 99.27%Couleur et forme :SolidMasse moléculaire :307.3UBS109
CAS :UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.Formule :C18H17N3ODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :291.35Ref: TM-T88314
2mg38,00€5mg57,00€10mg92,00€25mg166,00€50mg254,00€100mg389,00€200mg566,00€1mL*10mM (DMSO)63,00€AM103
CAS :AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).Formule :C36H38N3NaO4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :631.76Evixapodlin
CAS :Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.Formule :C34H36Cl2N8O4Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :691.61Ref: TM-T36487
1mg111,00€5mg264,00€10mg424,00€25mg747,00€50mg1.008,00€100mg1.359,00€200mg1.833,00€1mL*10mM (DMSO)405,00€HOIPIN-8 sodium
CAS :HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.Formule :C23H15F2N4NaO3Degré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :456.38Ref: TM-T62826
1mg70,00€5mg154,00€10mg235,00€25mg378,00€50mg540,00€100mg747,00€200mg1.026,00€1mL*10mM (DMSO)155,00€KI696
CAS :KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Formule :C28H30N4O6SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :550.63Ref: TM-T11758L
1mg144,00€5mg298,00€10mg445,00€25mg747,00€50mg1.074,00€100mg1.549,00€200mg2.072,00€1mL*10mM (DMSO)360,00€VVD-130037
CAS :VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Formule :C17H17ClN4O2Degré de pureté :99.01% - 99.92%Couleur et forme :SolidMasse moléculaire :344.8Ref: TM-T88838
1mg148,00€5mg357,00€10mg522,00€25mg833,00€50mg1.103,00€100mg1.508,00€1mL*10mM (DMSO)390,00€2-Selenouracil
CAS :2-Selenouracil is a specialized photosensitizer for photodynamical therapy.Formule :C4H4N2OSeCouleur et forme :SolidMasse moléculaire :175.05PSB-12379
CAS :PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).Formule :C18H23N5O9P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.35NSC23925
CAS :NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Formule :C22H26Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.36Veledimex
CAS :Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.Formule :C27H38N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.69a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS :Formule :C22H29FO5Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :392.4611α-Terpineol
CAS :<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.2511β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS :Formule :C21H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.459911β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS :Formule :C21H28O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.4440(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS :Formule :C24H31FO6Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :434.4977DEXAMETHASONE
CAS :Formule :C22H29FO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.4611RIDR-PI-103
CAS :RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug featuring an autocyclized portion connected to the pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhibited synergistic inhibition of cancer cell proliferation.Formule :C27H25N7O4Couleur et forme :SolidMasse moléculaire :511.53Xibornol
CAS :Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formule :C18H26OCouleur et forme :SolidMasse moléculaire :258.4Aurothioglucose
CAS :Aurothioglucose is a active-site TrxR1 inhibitor.Formule :C6H11AuO5SDegré de pureté :98%Couleur et forme :Yellow Crystals SolidMasse moléculaire :392.18Nogapendekin alfa inbakicept
CAS :Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).Couleur et forme :SolidSTING agonist-22
CAS :<p>STING agonist-22 (CF501) boosts vaccines by activating STING, inducing IFN-I and cytokines, aiding in SARS-CoV-2 research.</p>Formule :C40H48N14O6Couleur et forme :SolidMasse moléculaire :820.9Di-O-methyldemethoxycurcumin
CAS :Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.Formule :C22H22O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41gp91ds-tat
<p>gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.</p>Degré de pureté :98%Couleur et forme :SolidTacalcitol
CAS :Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.Formule :C27H44O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.64Racemic Naproxen
CAS :Racemic Naproxen is a biochemical substance.Formule :C14H14O3Degré de pureté :98%Couleur et forme :Crystals From Acetone-Hexane White SolidMasse moléculaire :230.26Icatolimab
<p>Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.</p>Degré de pureté :98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaTripeptide-41
CAS :Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.Formule :C29H30N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.57TLQP-21 TFA
<p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>Degré de pureté :98%Couleur et forme :Liquid2,3-Bis(3-indolylmethyl)indole
CAS :2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.Formule :C26H21N3Couleur et forme :SolidMasse moléculaire :375.475JH-X-119-01 hydrochloride
CAS :JH-X-119-01 hydrochloride is a potent, selective inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) that effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.Formule :C25H21ClN6O3Couleur et forme :SolidMasse moléculaire :488.93Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Formule :C67H127F3N10O14SDegré de pureté :99.90%Couleur et forme :SoildMasse moléculaire :1385.84Magnesium citrate
CAS :Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.Formule :C12H10Mg3O14Couleur et forme :SolidMasse moléculaire :451.113TLR7/8/9 antagonist 2
CAS :TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.Formule :C23H31N7Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :405.54Elamipretide acetate
<p>Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.</p>Formule :C34H53N9O7Degré de pureté :99.76%Couleur et forme :SoildMasse moléculaire :699.84TLQP-21 TFA
<p>TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。</p>Degré de pureté :98%ARGX-112
CAS :<p>Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.</p>Couleur et forme :Odour LiquidL-NIO dihydrochloride
CAS :L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.Formule :C7H16ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :209.67ALPK1-IN-1
CAS :<p>ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.</p>Formule :C25H32N6O2SCouleur et forme :SolidMasse moléculaire :480.63ALPK1-IN-2
CAS :<p>ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).</p>Formule :C20H18F2N4O2SCouleur et forme :SolidMasse moléculaire :416.44ALPK1-IN-3
CAS :<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Formule :C20H16F2N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.43
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