Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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GPCR Compound Library
<p>A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target</p>Couleur et forme :Odour SolidDeacetylgedunin
CAS :<p>Deacetylgedunin is a limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica.</p>Formule :C26H32O6Couleur et forme :SolidMasse moléculaire :440.53HNW005
<p>HNW005 is a dual inhibitor targeting the NLRP3 inflammasome and urate transporter 1 (URAT1). It exhibits an inhibition constant (KD) of 204.6 nM and an IC50 of 1.7 μM for NLRP3 inflammasome activation, while demonstrating an IC50 of 6.4 μM for inhibiting uric acid transmembrane transport. At an administered dose of 2 mg/kg in vivo, HNW005 achieves a uric acid reduction rate of 64.8%, effectively providing anti-inflammatory, analgesic, and urate-lowering effects by inhibiting NLRP3 inflammasome activation and uric acid transport. HNW005 is applicable for research in gouty arthritis.</p>Couleur et forme :Odour SolidFletikumab
CAS :<p>Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :146.48 kDaPS 1145 dihydrochloride
CAS :<p>IκB kinase (IKK) inhibitor</p>Formule :C17H13Cl3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.67Topramezone
CAS :<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Formule :C16H17N3O5SCouleur et forme :SolidMasse moléculaire :363.39Itolizumab
CAS :<p>Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6.</p>Degré de pureté :> 95%Couleur et forme :LiquidMasse moléculaire :144.82 kDaPterisolic acid B
<p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>Formule :C20H26O4Couleur et forme :SolidMasse moléculaire :330.424Xanthine oxidase-IN-12
<p>Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally</p>Degré de pureté :98%Couleur et forme :Odour SolidMTvkPABC-P5
<p>MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1</p>Formule :C52H73N11O14Couleur et forme :SolidMasse moléculaire :1076.2MAPK Inhibitor Library
<p>A unique collection of 365 compounds targeting MAPK signaling for drug discovery in MAPK related diseases;</p>Couleur et forme :Odour SolidGuretolimod hydrochloride
<p>Guretolimod hydrochloride acts as an agonist for Toll-like receptor 7 (TLR7) [1].</p>Formule :C24H35ClF3N5O4Couleur et forme :SolidMasse moléculaire :550.01Biotin-labeled ODN 2216 sodium
<p>Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour Solid3-Hydroxykynurenamine
CAS :<p>3-Hydroxykynurenamine (3-HKA) is a tryptophan metabolite with anti-inflammatory effects, reducing cytokines and aiding in models of psoriasis and nephritis.</p>Formule :C9H12N2O2Couleur et forme :SolidMasse moléculaire :180.2N(G)-Nitroarginine-4-nitroanilide
CAS :<p>N(G)-Nitroarginine-4-nitroanilide is an anti-nociceptive in mice.</p>Formule :C12H17N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.31DA-E 5090
CAS :<p>DA-E 5090, an active metabolite of E 5090, inhibits IL-1 production in human monocytes.</p>Formule :C17H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.32Sacituzumab tirumotecan
CAS :<p>Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).</p>Degré de pureté :99%Couleur et forme :LiquidSTING agonist-17
CAS :<p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>Formule :C43H53N13O8Couleur et forme :SolidMasse moléculaire :879.96Nonsteroidal Anti-Inflammatory Compound Library
<p>xnum non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.</p>Couleur et forme :Odour Solid3-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Formule :C30H42O6Couleur et forme :SolidMasse moléculaire :498.66Biotin-labeled ODN 1018 sodium
<p>Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through</p>Couleur et forme :Odour SolidPost-Translational Modification Compound Library
<p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>Couleur et forme :Odour SolidPIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Formule :C71H123N19O21S2·xC2HF3O2Couleur et forme :SolidFITC-labeled ODN 1668 sodium
<p>FITC-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN), functions as a TLR9 agonist.</p>Couleur et forme :Odour SolidInhibitor Library
<p>A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>Couleur et forme :Odour SolidAnti-inflammatory agent 59
<p>Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM.</p>Couleur et forme :Odour SolidProstaglandin D synthase
CAS :<p>Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type prostaglandin D synthase (L-PGDS) is found in human coronary atherosclerotic plaques and can be detected in human serum.</p>Couleur et forme :SolidL-156,602
CAS :<p>L-156,602 has a wide range of applications in life science related research.</p>Formule :C38H64N8O13Couleur et forme :SolidMasse moléculaire :840.973Ziltivekimab
CAS :<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Degré de pureté :95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :SoildSDH-IN-23
<p>SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.</p>Formule :C19H11ClF6N2O2Couleur et forme :SolidMasse moléculaire :448.75PROTAC IRAK4 degrader-3
CAS :<p>PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.</p>Formule :C57H68FN11O8SCouleur et forme :SolidMasse moléculaire :1086.3Endoplasmic Reticulum Stress Compound Library
<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>Couleur et forme :Odour SolidArginase inhibitor 9
<p>Arginase inhibitor9 (Compound 12a) is a type of arginase enzyme inhibitor with IC50 values of 9 μM for bovine and 55 μM for human arginase I. It also exhibits antioxidant activity by scavenging free radicals. Moreover, Arginase inhibitor9 effectively regulates collagen and procollagen levels, thereby exerting an anti-fibrotic effect.</p>Formule :C13H11NO4SCouleur et forme :SolidMasse moléculaire :277.3Nuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Couleur et forme :Odour SolidODN D-SL03
CAS :<p>ODN D-SL03, a C class CpG oligonucleotide, stimulates PBMCs, activating B cells, NK cells & monocytes, and can inhibit tumor growth.</p>Couleur et forme :SolidMasse moléculaire :9345Amfenac sodium
CAS :<p>Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.</p>Formule :C15H12NNaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.268-Nitroguanine
CAS :<p>8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant</p>Formule :C5H4N6O3Couleur et forme :SolidMasse moléculaire :196.12IL-1β-IN-1
CAS :<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Formule :C22H34O2Couleur et forme :SolidMasse moléculaire :330.5(±)11(12)-EET
CAS :<p>(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47ENUM006
<p>ENUM006 is a human monoclonal antibody (mAb) that targets CD223/LAG3.</p>Couleur et forme :Odour LiquidBavunalimab
CAS :<p>Bavunalimab: bispecific anti-CTLA-4/LAG-3 antibody, T-cell activator in NSG mice, for cancer research.</p>Couleur et forme :LiquidNasunin
CAS :<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formule :C42H47ClO23Couleur et forme :SolidMasse moléculaire :955.26Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Couleur et forme :Odour SolidMyD88-IN-1
CAS :<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formule :C23H24N6O7SDegré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :528.54Inflexuside B
CAS :<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Formule :C35H48O11Couleur et forme :SolidMasse moléculaire :644.75Antiparasitic agent-26
<p>Antiparasitic agent-26 (Compound 8) is an antiparasitic compound that effectively inhibits the growth of Naegleria fowleri, with an IC50 of 22.87 μM (trophozoite stage) and 25.16 μM (cyst stage). It exerts its antiparasitic effects by inducing programmed cell death, which includes cytosolic calcium accumulation, mitochondrial membrane potential collapse, ATP synthesis inhibition, ROS accumulation, and chromatin condensation. Antiparasitic agent-26 can be utilized in research on primary amoebic meningoencephalitis (PAM).</p>Couleur et forme :Odour Solid1-Hydroxy-ibuprofen
CAS :<p>1-Hydroxy Ibuprofen, a metabolite in P. australis, targets COX-1/COX-2 with IC50s: 13 μM/370 μM.</p>Formule :C13H18O3Couleur et forme :SolidMasse moléculaire :222.2802Antibacterial agent 119
<p>Antibacterialagent 119 (Compound 21 g) is a potential antibacterial agent effective against methicillin-resistant Staphylococcus aureus, with a minimum inhibitory concentration (MIC) of less than 1 μg/mL against tested strains. It induces reactive oxygen species (ROS) generation and disrupts bacterial cell membranes, causing their rupture. Antibacterialagent 119 exhibits strong antimicrobial activity, low cytotoxicity, rapid bactericidal action, and favorable in vivo antibacterial efficacy.</p>Formule :C42H54BrClN2O4Couleur et forme :SolidMasse moléculaire :766.246Exosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Couleur et forme :Odour SolidLemnalol
CAS :<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formule :C15H24ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.35TGF-β/Smad Compound Library
<p>A unique collection of xnum TGF-beta/Smad signaling targeted compounds for high throughput and high content screening;</p>Couleur et forme :Odour SolidFSL-1
CAS :<p>TLR2/6 agonist, may bind TLR10. Activates NF-κB, triggers IL-8, IL-1β, CCL20, TNF-α. Boosts IFNγ-induced CXCL10 in melanoma.</p>Formule :C84H140N14O18SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1666.16Nurulimab
CAS :<p>Nurulimab (BCD-145) is an anti-CTLA-4 antibody with anti-cancer activity for the study of skin and musculoskeletal diseases.</p>Degré de pureté :95.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 95.5% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :LiquidBRCA2-IN-1
<p>BRCA2-IN-1 (Compound 3j) is a potential BRCA2 inhibitor with antiproliferative activity against the breast cancer MCF-7 cell line. This compound also demonstrates DPPH radical scavenging ability, with an IC50 value of 12.36 µM.</p>Couleur et forme :Odour SolidTLR4-IN-C34-C2-amide-C6-OH
<p>TLR4-IN-C34-C2-amide-C6-OH: a linker with TLR4-IN-C34 that curbs TLR4 and inflammation in mice.</p>Formule :C25H42N2O11Couleur et forme :SolidMasse moléculaire :546.61Perfluorododecanoic acid
CAS :<p>Perfluorododecanoic acid (PFDoA) is a PFAS pollutant causing ROS increase, mitochondrial damage, and neuronal cytotoxicity.</p>Formule :C12HF23O2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :614.1COX-2/15-LOX-IN-3
<p>COX-2/15-LOX-IN-3 (compound 5k) serves as a dual inhibitor for COX-2 and 15-LOX, demonstrating inhibitory concentrations (IC50) of 0.075 μM and 1.97 μM,</p>Formule :C25H24FN3O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :465.54Noraramtide
CAS :<p>Noraramtide (BHV-1100) is an antibody recruiting molecule that specifically binds to the CD38 molecule to recruit natural killer (NK) cells. This interaction enhances the NK cells' ability to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while preventing mutual NK cell destruction. Noraramtide is utilized in research on autologous cancer immunotherapy.</p>Formule :C210H300N48O65S3Couleur et forme :SolidMasse moléculaire :4633.11Lonazolac Calcium
CAS :<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Formule :C34H24CaCl2N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :663.56iNOs-IN-6
<p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>Couleur et forme :Odour SolidCOX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Couleur et forme :Odour SolidBMS-986251
CAS :<p>BMS-986251: Oral RORγt inverse agonist, EC50 12 nM; inhibits IL-17 (EC50 24 nM); effective in mouse psoriasis models.</p>Formule :C30H29F8NO5SCouleur et forme :SolidMasse moléculaire :667.61TSR-033
CAS :<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Couleur et forme :LiquidDithianon
CAS :<p>Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.</p>Formule :C14H4N2O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.32TPNA10168
CAS :<p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C9H9ClO2S2Couleur et forme :SolidMasse moléculaire :248.75Aspulvinone O
CAS :<p>Aspulvinone O, from P. variotti, is an antioxidant with anticancer properties, inhibits GOT1, and reduces SW1990 pancreatic tumor growth in mice.</p>Formule :C27H28O6Couleur et forme :SolidMasse moléculaire :448.515iE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Formule :C12H23Cl2N3O7Couleur et forme :SolidMasse moléculaire :391.09131CD73-IN-16
<p>CD73-IN-16 (compound 18) acts as an inhibitor of hCD73, exhibiting an IC50 value of 0.28 μM.</p>Couleur et forme :Odour SolidNLRP3-IN-46
<p>NLRP3-IN-46 (Compound 3k) activates the cholinergic anti-inflammatory pathway involved in neuro-immune modulation, thereby inhibiting the activation of the NLRP3 inflammasome. Furthermore, NLRP3-IN-46 suppresses the production of IL-1β in THP-1 cells induced by Uric acid sodium, making it relevant for research in gouty arthritis.</p>Couleur et forme :Odour SolidAllyl methyl trisulfide
CAS :<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Formule :C4H8S3Couleur et forme :SolidMasse moléculaire :152.3Anti-Human MSLN Antibody (Clone HN1)
<p>Anti-Human MSLN Antibody (Clone HN1) is a humanised monoclonal antibody targeting MSLN (Mesothelin), , blocks the interaction between MSLN and CA125, cancer .</p>Degré de pureté :95%Couleur et forme :Odour LiquidFITC-labeled ODN 1018 sodium
<p>FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal</p>Couleur et forme :SolidMasse moléculaire :8171Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.409Huangjiangsu A
CAS :<p>Huangjiangsu A, from D. villosa, may protect the liver from H2O2 damage and reduce ROS, showing therapeutic promise.</p>Formule :C51H82O22Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1047.18Polyinosinic acid
CAS :<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Formule :(C10H13N4O8P)xCouleur et forme :SolidUbletamig
CAS :<p>Ubletamig is a humanized IgG4κ monoclonal antibody that targets MUC16.</p>Couleur et forme :LiquidSTING agonist-25
CAS :<p>STING agonist-25 is a non-nucleotide that activates STING, enhances immune response, and is active against SARS-CoV strains.</p>Formule :C36H41N13O6Couleur et forme :SolidMasse moléculaire :751.79KYN-101
CAS :<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formule :C22H19FN6Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :386.43cGAMP disodium
CAS :<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Formule :C20H24N10O13P2·2NaCouleur et forme :SoildMasse moléculaire :720.39CD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Couleur et forme :SolidPhytoene desaturase-IN-1
CAS :<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Formule :C18H13ClF3N3O2SCouleur et forme :SolidMasse moléculaire :427.83MAO-B-IN-39
<p>MAO-B-IN-39 (compound11) is a potent inhibitor of monoamine oxidase B (MAO-B), with an IC50 of 3.61 μM. It demonstrates strong NRF2 induction capabilities and exhibits significant anti-inflammatory and neuroprotective effects in oxidative stress-related in vitro models. Additionally, MAO-B-IN-39 shows high liver microsomal stability and favorable pharmacokinetic properties in mice, making it a valuable compound for Parkinson's disease research.</p>Formule :C17H13FN2OCouleur et forme :SolidMasse moléculaire :280.3Valeriandoid F
CAS :<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Formule :C23H34O9Couleur et forme :SolidMasse moléculaire :454.516COX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Formule :C27H26N6OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.66Feeblin
CAS :<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Formule :C27H33N3O2Degré de pureté :99.58% - 99.88%Couleur et forme :SoildMasse moléculaire :431.57Biotin-labeled ODN 2088 sodium
<p>Biotin-labeled ODN 2088 (sodium) acts as a potent inhibitor of TLR3, TLR7, and TLR9.</p>Couleur et forme :Odour SolidCbl-b-IN-28
<p>Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.</p>Couleur et forme :Odour SolidCarboxy-PTIO
CAS :<p>Carboxy-PTIO rapidly scavenges NO, forming NO2, key in preventing hypotension and shock in rats.</p>Formule :C14H17N2O4Couleur et forme :SolidMasse moléculaire :277.3PROTAC STING Degrader-1
CAS :<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Formule :C34H33N7O10Couleur et forme :SolidMasse moléculaire :699.67Sacituzumab MMAE
<p>Sacituzumab-MMAE (CHB295) Anti-TROP2 Reference Antibody is produced in CHO cells and consists of a huIgG1 heavy chain and a hukappa light chain. This compound has a predicted molecular weight (MW) of 146.06 kDa.</p>Couleur et forme :LiquidMasse moléculaire :150 kDaNF-κΒ activator 1
CAS :<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formule :C16H11FN2O2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :314.33Anti-inflammatory agent 78
<p>Anti-inflammatory agent 78 (compound L-37) is a potent anti-inflammatory agent. It effectively inhibits PGE2, PGE1, COX-2, and COX-1. Additionally, Anti-inflammatory agent 78 suppresses the release of NO in LPS-stimulated RAW 264.7 cell lines.</p>Formule :C19H14ClNO4Masse moléculaire :355.061143-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
CAS :<p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>Formule :C28H24ClN3O6Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :533.96PNT2001
CAS :<p>PNT2001 (LY4181530) is an effective prostate-specific membrane antigen (PSMA) ligand with an IC50 of 3.1 nM. It enhances cellular internalization and, when labeled with 177Lu and 225Ac, is applicable for prostate cancer research.</p>Formule :C85H107N15O32Couleur et forme :SolidMasse moléculaire :1850.84β-Amyrin acetate
CAS :<p>Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>Formule :C32H52O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :468.75IL-17-IN-3
<p>IL-17-IN-3 (compound 11) is an IL-17A inhibitor with an IC50 value of 35 nM. In a rat tolerance study, it showed no adverse reactions when administered at doses up to 300 mg/kg/day for four consecutive days.</p>Formule :C22H25F6N5O3SCouleur et forme :SolidMasse moléculaire :553.521[12]-Dehydrogingerdione
CAS :<p>[12]-Dehydrogingerdione is a natural product found in ginger that has anti-neuroinflammatory activity.Cost-effective and quality-assured.</p>Formule :C23H34O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :374.51Aminopicoline
CAS :<p>Compound Fr16695, with CAS No. 695-34-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr16695 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Formule :C6H8N2Couleur et forme :White To Pale Yellow Solid FlakesMasse moléculaire :108.14Cyclic-di-GMP disodium
CAS :<p>Cyclic-di-GMP disodium (5GP-5GP disodium) is a STING agonist and a second messenger in bacteria.Cost-effective and quality-assured.</p>Formule :C20H22N10Na2O14P2Degré de pureté :98.98% - 99.93%Couleur et forme :SolidMasse moléculaire :734.38XJB-5-131
CAS :<p>XJB-5-131: synthetic, bi-functional antioxidant; targets mitochondria, scavenges ROS/electrons, protects CB MNCs from irradiation.</p>Formule :C53H80N7O9Couleur et forme :SolidMasse moléculaire :959.263
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