Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(142 produits)
- CXCR(159 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(110 produits)
- IκB/IKK(58 produits)
- LTR(3 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(429 produits)
- NOD(20 produits)
- NOS(61 produits)
- Nrf2(82 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(61 produits)
- TLR(75 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3382 produits trouvés pour "Immunologie et Inflammation"
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Refinicopan
CAS :Refinicopan is a complement factor D inhibitor with an IC50 of 10 nM, demonstrating an inhibition activity on rabbit erythrocyte hemolysis with an IC50 of 41 nM. It possesses excellent pharmacokinetic and pharmacodynamic properties.Formule :C29H32N2O3Couleur et forme :SolidMasse moléculaire :456.58PVTX-405
CAS :PVTX-405 is a selective oral IKZF2 molecular glue degrader with a DC50 of 0.7 nM and a maximum degradation (Dmax) of 91%. It enhances degradation efficiency, significantly reduces off-target degradation, and minimizes hERG inhibition with an IC50 of 48 µM. PVTX-405 effectively inhibits MC38 tumor growth in Crbn391VC57BL/6 mouse xenograft models and shows superior synergistic anticancer effects when combined with immune checkpoint therapies (ICTs) such as anti-PD1 or anti-LAG3 antibodies.Formule :C30H31N5O4Couleur et forme :SolidMasse moléculaire :525.60hDDAH-1-IN-2 sulfate
hDDAH-1-IN-2: selective oral hDDAH-1 inhibitor with low cell toxicity.Formule :C8H24N4O10S2Couleur et forme :SolidMasse moléculaire :400.43STING agonist-43
CAS :STINGagonist-43 (Compound 67) is a selective STING agonist with an EC50 of 20.53 μM. It selectively enhances the cGAMP-dependent STING pathway activation by modulating STING oligomerization. STINGagonist-43 demonstrates antitumor activity in a B16.F10 mouse melanoma model and can be utilized in cancer immunotherapy research.Formule :C21H23NO4Couleur et forme :SolidMasse moléculaire :353.41CYP1B1-IN-10
CAS :CYP1B1-IN-10 (Compound 15C) is a highly selective inhibitor of human cytochrome P450 1B1 (hCYP1B1) with an IC50 value of 0.11 μM. It shows promise for use in research focused on hormone-dependent tumors, including breast and ovarian cancers.Formule :C23H18N2Couleur et forme :SolidMasse moléculaire :322.40PSB-0963
CAS :PSB-0963 is a selective competitive extracellular 5'-nucleotidase (eN/CD73) inhibitor with a Ki value of 150 nM for rat extracellular 5'-nucleotidase. It exhibits greater selectivity compared to other extracellular nucleotidases (NTPDases 1-3) and P2Y receptors. PSB-0963 is applicable in cancer research.Formule :C28H17N2NaO5SCouleur et forme :SolidMasse moléculaire :516.50Antifungal agent 134
CAS :Antifungalagent 134 (Compound B13) is an antifungal agent effective against Botrytis cinerea, Alternaria solani, Fusarium graminearum, Rhizoctonia solani, Colletotrichum orbiculare, and Alternaria alternata with EC50 values of 3.24, 1.89, 1.70, 0.36, 4.27, and 1.50 μg/mL, respectively. It disrupts the fungal cell membranes and mitochondria, leading to substantial accumulation of reactive oxygen species (ROS). Additionally, Antifungalagent 134 exhibits significant herbicidal activity on field weeds such as Amaranthus retroflexus L and Abutilon theophrasti Medicus, and is applicable in crop disease and field weed research.Formule :C18H12F4N2O4Couleur et forme :SolidMasse moléculaire :396.29ZM514
ZM514 inhibits CD73 (hCD73 IC50: 1.39 μM, mCD73 IC50: 14.65 μM) with low cytotoxicity, suitable for cancer research.Formule :C36H57NO4Couleur et forme :SolidMasse moléculaire :567.84C5aR-IN-3
CAS :C5aR-IN-3, a potent C5aR inhibitor, may treat autoimmune and inflammatory diseases.Formule :C36H40FN5O3Couleur et forme :SolidMasse moléculaire :609.73TrxR-IN-5
TrxR-IN-5 (compound 4f) is an effective inhibitor of thioredoxin reductase (TrxR) with an IC₅₀ of 0.16 μM. anti-proliferative and anti-metastatic.Formule :C26H22O3Couleur et forme :SolidMasse moléculaire :382.46AM679
CAS :AM679 is a potent, selective FLAP inhibitor with strong leukotriene suppression in vivo, minimal CYP3A4 interaction, and excellent pharmacokinetics in rodent models.Formule :C40H44N4O5SDegré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :692.87Gardiquimod hydrochloride
CAS :Gardiquimod (hydrochloride) is an imidazoquinoline class TLR7/8 agonist. It can inhibit HIV-1 infection in macrophages and activated peripheral blood mononuclear cells (PBMCs). At concentrations below 10 μM, Gardiquimod (hydrochloride) specifically activates TLR7.Formule :C17H24ClN5OCouleur et forme :SolidMasse moléculaire :349.858IL-6-IN-2
CAS :IL-6-IN-2 (Compound 15) is an inhibitor of the interaction between IL-6 and IL-6R proteins. The compound's binding free energy (∆G) is −36.50 kcal/mol. In its binding with IL-6, the contributions from Lys66, Phe74, Gln175, Ser176, and Arg179 are -1.10, -8.68, -6.91, -3.69, and -1.72 kcal/mol, respectively. IL-6-IN-2 exhibits low gastrointestinal (GI) absorption rates.Formule :C26H24N4O3Couleur et forme :SolidMasse moléculaire :440.49Ocipumaltib
CAS :Ocipumaltib (Example 2) is an inhibitor of mucosa-associated lymphoid tissue protein 1 (MALT1). It functions as an antineoplastic agent and is utilized in the study of cancer, infections, neurological disorders, and hematological diseases.Formule :C20H16ClF3N8O2Couleur et forme :SolidMasse moléculaire :492.84Anti-inflammatory agent 23
Anti-inflammatory agent 23 blocks LPS-induced NO (IC50: 0.449 μM) and binds p65 well.Formule :C34H49NO6Couleur et forme :SolidMasse moléculaire :567.76Cyazofamid
CAS :Cyazofamid functions as a fungicide by impairing the production of ATP. It inhibits Organic Cation Transporter 3 (OCT3) and OAT1 with IC50 values of 1.54 and 17.3 μM, respectively.Formule :C13H13ClN4O2SCouleur et forme :SolidMasse moléculaire :324.79EGR-1-IN-3
CAS :EGR-1-IN-3 (Compound 36) is an inhibitor of early growth response 1 (EGR-1) binding to DNA. It effectively suppresses the binding of EGR-1 to DNA and the expression of inflammation-related genes (such as TSLP, IL-31, IL-6, and CCL2) induced by TNFα. This compound is applicable to the study of inflammatory diseases.Formule :C31H31N3O6SCouleur et forme :SolidMasse moléculaire :573.659α-Hydroxy alprazolam
CAS :α-Hydroxy alprazolam (U 40125), the primary metabolite of α-Hydroxy alprazolam, possesses pharmacological activity accounting for 60% of that of Alprazolam.Formule :C17H13ClN4OCouleur et forme :SolidMasse moléculaire :324.76Z-Val-Val-Nle-diazomethylketone
CAS :Z-Val-Val-Nle-diazomethylketone is an inhibitor of cathepsin S (CATS). It significantly suppresses the upregulation of IFNg-induced MHCII molecules, specifically HLA-DR and Ii-p33/35, while increasing the protein level of Ii-p10. This compound can be utilized for research into skin disorders such as psoriasis, atopic dermatitis, and actinic keratosis.Formule :C25H37N5O5Couleur et forme :SolidMasse moléculaire :487.59TMV-IN-8
CAS :TMV-IN-8 (compound 7d) is an anti-tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL. TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppresses TMV coat protein gene expression and biosynthesis process [1].Formule :C26H22N6O4Couleur et forme :SolidMasse moléculaire :482.49AS2690168 hydrochloride
CAS :AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.Formule :C17H15Cl2F3N4OCouleur et forme :SolidMasse moléculaire :419.228Creatine ethyl ester
CAS :Creatine ethyl ester (CEE) is a readily available form of creatine commonly used in supplements. It can upregulate TLRs (TLR2, 3, 4, and TLR7) over a short period.Formule :C6H13N3O2Couleur et forme :SolidMasse moléculaire :159.186Pelecopan
CAS :Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).Formule :C23H19FN2O4Couleur et forme :SolidMasse moléculaire :406.41Galectin-3-IN-3
CAS :Galectin-3-IN-3 (Compound 4) serves as a selective and orally active inhibitor targeting Gal-3. It exhibits IC50 values of 11 nM for mGal-3 and 84 nM for hGal-3 [1].Formule :C25H22ClF2N7O4SCouleur et forme :SolidMasse moléculaire :590.00HTS05585
CAS :HTS05585 (Compound Hit-1) is a selective inhibitor of macrophage migration inhibitory factor (MIF) with a Kd value of 0.29 μM determined by microscale thermophoresis (MST) and confirmed through isothermal titration calorimetry (ITC) at 0.32 μM. It suppresses the release of pro-inflammatory factors (TNF-α, IL-6, IL-1β) in macrophages induced by LPS, making it a promising candidate for the study of inflammatory diseases such as sepsis.Formule :C18H15N3OCouleur et forme :SolidMasse moléculaire :289.33MALT1-IN-11
CAS :MALT1-IN-11: MALT1 inhibitor, IC50 <10-100 nM, reduces IL10, for cancer/autoimmune research.Formule :C20H16F4N8OCouleur et forme :SolidMasse moléculaire :460.39COX-2-IN-7
COX-2-IN-7: potent, orally active COX-2 inhibitor with higher selectivity than Celecoxib, IC50 6.585 uM, anti-inflammatory, low ulcer risk.Formule :C15H13N3O2S2Couleur et forme :SolidMasse moléculaire :331.41ODN 2088
CAS :ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.Couleur et forme :SolidALR-6
CAS :<p>ALR-6, an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP, possesses anti-inflammatory properties. It significantly inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without substantially affecting direct inhibition of 5-LOX [1].</p>Formule :C18H14O5Couleur et forme :SolidMasse moléculaire :310.3Corannulene
CAS :<p>Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.</p>Formule :C20H10Couleur et forme :SolidMasse moléculaire :250.293Indeno[1,2,3-cd]pyrene
CAS :Indeno[1,2,3-cd]pyrene, a polycyclic aromatic hydrocarbon, exhibits moderate cytotoxicity to human alveolar epithelial cells (HPAEpiC). Additionally, it enhances allergic pulmonary inflammation responses through the activation of the aryl hydrocarbon receptor.Formule :C22H12Couleur et forme :SolidMasse moléculaire :276.33AhR agonist 7
CAS :Compound 8, an AhR agonist 7, demonstrates potent activation of AhR with an EC50 of 13nM [1].Formule :C16H15ClFNO2Couleur et forme :SolidMasse moléculaire :307.75MAY0132
CAS :MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.Formule :C16H15ClF3NCouleur et forme :SolidMasse moléculaire :313.745COX-2-IN-12
COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.Formule :C17H19NO3Couleur et forme :SolidMasse moléculaire :285.342-Guanidinobezimidazole
CAS :<p>2-Guanidinobenzimidazole (2GBI) is a selective agonist of NLRP3, with a KD value of 1.29 μM for His-GFP-NLRP3. It directly binds to the LRR domain of NLRP3, facilitating the assembly and activation of the inflammasome. Additionally, 2-Guanidinobenzimidazole enhances antitumor immunity, inhibits tumor growth, and overcomes resistance to immune checkpoint blockade (ICB).</p>Formule :C8H9N5Couleur et forme :SolidMasse moléculaire :175.191STING agonist-21
CAS :STING agonist-21 (compound 1), possessing an EC 50 of 592.8 nM, functions as a STING agonist. It is applicable in cancer research [1].Formule :C17H11F6N5O2Couleur et forme :SolidMasse moléculaire :431.29TLR7 agonist 28
CAS :TLR7 agonist28 (compound 3) is a potent TLR7 agonist. This compound can be combined with anti-tumor monoclonal antibodies (mAb) for use in cancer immunotherapy.Formule :C26H25N9O7Couleur et forme :SolidMasse moléculaire :575.533AMS-17
AMS-17, a strong NLRP3 inhibitor, quells microglia activation and cytokines like caspase-1, TNF-α, IL-1β, iNOS in studies.Formule :C15H13F3N4O3SCouleur et forme :SolidMasse moléculaire :386.35YM-I-26
CAS :YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of β-amyloid in murine microglial BV2 cells and reduces the production of IL-1β and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.Formule :C28H33ClN2O5S2Couleur et forme :SolidMasse moléculaire :577.164-Octylphenol
CAS :4-Octylphenol is an endocrine disruptor with gender-specific effects on male germ cells, significantly reducing the mitotic index and the number of spermatogonia. It also causes inflammatory damage in the gills of carp by activating the complement system through the C3a/C3a receptor (C3a/C3aR) axis and C5a/C5a receptor 1 (C5a/C5aR1) axis. Furthermore, 4-Octylphenol induces immune suppression by disrupting the balance between helper T (Th) cells 1/Th2 and regulatory T (Treg)/Th17 cells, and triggers inflammatory damage through the Toll-like receptor 7 (Toll-like Receptor (TLR))/inhibitor κBα/nuclear factor κB (TLR7/IκBα/NF-κB) pathway.Formule :C14H22OCouleur et forme :SolidMasse moléculaire :206.32AM103
CAS :AM103 is an effective and selective inhibitor of FLAP (IC50 = 4.2 nM).Formule :C36H38N3NaO4SDegré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :631.76KI696
CAS :KI696 is a high-affinity probe that potently inhibits the interaction of Keap1 and NRF2.Formule :C28H30N4O6SDegré de pureté :99.74%Couleur et forme :SolidMasse moléculaire :550.63Ref: TM-T11758L
1mg144,00€5mg298,00€10mg445,00€25mg747,00€50mg1.074,00€100mg1.549,00€200mg2.072,00€1mL*10mM (DMSO)360,00€UBS109
CAS :UBS109, a curcumin analog, is a DNA demethylating agent in pancreatic cancer that promotes osteoblast differentiation and mineralization.Formule :C18H17N3ODegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :291.35Ref: TM-T88314
2mg38,00€5mg57,00€10mg92,00€25mg166,00€50mg254,00€100mg389,00€200mg566,00€1mL*10mM (DMSO)63,00€Evixapodlin
CAS :Evixapodlin (PD-1/PD-L1-IN 7) is a human PD-1/PD-L1 protein/protein interaction inhibitor (IC50: 0.213).Evixapodlin has anticancer and antiviral activities.Formule :C34H36Cl2N8O4Degré de pureté :97.02%Couleur et forme :SolidMasse moléculaire :691.61Ref: TM-T36487
1mg111,00€5mg264,00€10mg424,00€25mg747,00€50mg1.008,00€100mg1.359,00€200mg1.833,00€1mL*10mM (DMSO)405,00€Dazostinag disodium
CAS :<p>Dazostinag disodium (TAK-676) is a synthetic novel interferon gene (STING) agonist.Cost-effective and quality-assured.</p>Formule :C21H20F2N8Na2O10P2S2Degré de pureté :98.84% - 99.96%Couleur et forme :SolidMasse moléculaire :754.48VVD-130037
CAS :VVD-130037 is a KEAP1 activator with potential antitumor activity.VVD-130037 inhibits tumor growth in advanced solid tumors by degrading NRF2.Formule :C17H17ClN4O2Degré de pureté :99.01% - 99.92%Couleur et forme :SolidMasse moléculaire :344.8Ref: TM-T88838
1mg148,00€5mg357,00€10mg522,00€25mg833,00€50mg1.103,00€100mg1.508,00€1mL*10mM (DMSO)390,00€HOIPIN-8 sodium
CAS :HOIPIN-8 sodium is a LUBAC inhibitor for the study of inflammatory and immune diseases.Formule :C23H15F2N4NaO3Degré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :456.38Ref: TM-T62826
1mg70,00€5mg154,00€10mg235,00€25mg378,00€50mg540,00€100mg747,00€200mg1.026,00€1mL*10mM (DMSO)155,00€Antiproliferative agent-22
CAS :Antiproliferative agent-22 is an anticancer compound that shows antiproliferative activity on MCF-7, MDA-MB-231 and MDA-MB-468 cells.Formule :C17H13N3O3Degré de pureté :99.20% - 99.27%Couleur et forme :SolidMasse moléculaire :307.32-Selenouracil
CAS :2-Selenouracil is a specialized photosensitizer for photodynamical therapy.Formule :C4H4N2OSeCouleur et forme :SolidMasse moléculaire :175.05NSC23925
CAS :NSC23925 is a selective and effective inhibitor of P-glycoprotein (Pgp).Formule :C22H26Cl2N2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :421.36Veledimex
CAS :Veledimex is an oral activator ligand for a proprietary gene therapy promoter system. It is also a moderate inhibitor of and substrate for CYP3A4/5.Formule :C27H38N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.6PSB-12379
CAS :PSB-12379 is a potent inhibitor of Ecto-5'-Nucleotidase (CD73)(Kis of 9.03 nM (rat) and 2.21 nM (human)).Formule :C18H23N5O9P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :515.3511β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione
CAS :Formule :C21H28O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :360.4440(11β,16α)-9-Fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregna-1,4-diene-3,20-dione
CAS :Formule :C24H31FO6Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :434.49779a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione
CAS :Formule :C22H29FO5Degré de pureté :99%Couleur et forme :SolidMasse moléculaire :392.4611α-Terpineol
CAS :<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Formule :C10H18ODegré de pureté :97.55%Couleur et forme :Colorless LiquidMasse moléculaire :154.2511β,17α,21-Trihydroxypregn-4-ene-3,20-dione
CAS :Formule :C21H30O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.4599DEXAMETHASONE
CAS :Formule :C22H29FO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :392.4611JH-X-119-01 hydrochloride
CAS :JH-X-119-01 hydrochloride is a potent, selective inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) that effectively alleviates lipopolysaccharide (LPS)-induced sepsis in mice.Formule :C25H21ClN6O3Couleur et forme :SolidMasse moléculaire :488.93TLR7/8/9 antagonist 2
CAS :TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. It inhibits HEK/hTLR7, HEK/hTLR8, and HEK/hTLR9 with IC50s of 0.011 μM, 0.029 μM, and 0.052 μM, respectively. TLR7/8/9 antagonist 2 can be used to study auto-inflammatory diseases such as systemic lupus erythematosus or lupus nephritis.Formule :C23H31N7Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :405.54Elamipretide acetate
<p>Elamipretide acetate (MTP 131), a small tetrapeptide, targets mitochondria to reduce toxic species and stabilize cardiolipin.</p>Formule :C34H53N9O7Degré de pureté :99.76%Couleur et forme :SoildMasse moléculaire :699.84Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, and can be used to study the effects of lipoproteins on the periodontium.Formule :C67H127F3N10O14SDegré de pureté :99.90%Couleur et forme :SoildMasse moléculaire :1385.84RIDR-PI-103
CAS :RIDR-PI-103 is a reactive oxygen species (ROS)-induced drug release prodrug featuring an autocyclized portion connected to the pan-PI3K inhibitor (PI-103). In MDA-MB-361 and MDA-MB-231 cells, Doxorubicin and RIDR-PI-103 exhibited synergistic inhibition of cancer cell proliferation.Formule :C27H25N7O4Couleur et forme :SolidMasse moléculaire :511.53Racemic Naproxen
CAS :Racemic Naproxen is a biochemical substance.Formule :C14H14O3Degré de pureté :98%Couleur et forme :Crystals From Acetone-Hexane White SolidMasse moléculaire :230.26Icatolimab
<p>Icatolimab (JS-004) is a humanized antibody targeting BTLA/CD272 for the study of lymphomas and solid tumors.</p>Degré de pureté :98.7% (SDS-PAGE); 95.6% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaTripeptide-41
CAS :Tripeptide-41 (CG-Lipoxyn) is a bioactive peptide known for its ability to reduce fat accumulation.Formule :C29H30N4O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.57Di-O-methyldemethoxycurcumin
CAS :Di-O-methyldemethoxycurcumin is a Curcumin analog isolated from medicinal plant turmeric di-orthomethyldemethoxycurcumin, anti-inflammatory and antioxidant properties Inhibition of IL-6 production, EC50 is 16.20μg/mL.Formule :C22H22O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :366.41Magnesium citrate
CAS :Magnesium citrate is a useful organic compound for research related to life sciences. The catalog number is T64455 and the CAS number is 3344-18-1.Formule :C12H10Mg3O14Couleur et forme :SolidMasse moléculaire :451.113gp91ds-tat
<p>gp91ds-tat is a useful organic compound for research related to life sciences and the catalog number is T35393.</p>Degré de pureté :98%Couleur et forme :SolidNogapendekin alfa inbakicept
CAS :Nogapendekin alfa inbakicept is an IL-15 superagonist that enhances anti-tumor immune responses by activating NK cells and T cells. It is being studied for use in non-muscle invasive bladder cancer (NMIBC).Couleur et forme :SolidTacalcitol
CAS :Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) promotes normal bone development by regulating calcium and modulates immunological and inflammatory processes.Formule :C27H44O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :416.642,3-Bis(3-indolylmethyl)indole
CAS :2,3-Bis(3-indolylmethyl)indole exhibits a concentration-dependent inhibition of RANKL-induced osteoclastogenesis, actin ring formation, and bone resorption.Formule :C26H21N3Couleur et forme :SolidMasse moléculaire :375.475Aurothioglucose
CAS :Aurothioglucose is a active-site TrxR1 inhibitor.Formule :C6H11AuO5SDegré de pureté :98%Couleur et forme :Yellow Crystals SolidMasse moléculaire :392.18Xibornol
CAS :Xibornol (Nanbacine) 具有广谱的抗菌和抗病毒活性，可用于研究革兰氏阳性菌感染和人呼吸道合胞病毒与人冠状病毒229E感染。Formule :C18H26OCouleur et forme :SolidMasse moléculaire :258.4TLQP-21 TFA
<p>TLQP-21 TFA is a VGF-derived peptide, C3aR1 agonist (mouse EC50: 10.3μM; human EC50: 68.8μM), that raises intracellular Ca2+ for nociception research.</p>Degré de pureté :98%Couleur et forme :LiquidSTING agonist-22
CAS :<p>STING agonist-22 (CF501) boosts vaccines by activating STING, inducing IFN-I and cytokines, aiding in SARS-CoV-2 research.</p>Formule :C40H48N14O6Couleur et forme :SolidMasse moléculaire :820.9TLQP-21 TFA
<p>TLQP-21 TFA （TLQP-21 Trifluoroacetate） 是一种 VGF 衍生肽，可通过结合后折叠机制激活C3aR1 受体。</p>Degré de pureté :98%ARGX-112
CAS :<p>Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.</p>Couleur et forme :Odour LiquidL-NIO dihydrochloride
CAS :L-NIO dihydrochloride, a potent and non-selective NADPH-dependent nitric oxide synthase (NOS) inhibitor, consistently induces focal ischemic infarct in rats. It exhibits inhibitory constants (Kis) of 1.7, 3.9, and 3.9 μM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS) forms, respectively.Formule :C7H16ClN3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :209.67ALPK1-IN-1
CAS :<p>ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.</p>Formule :C25H32N6O2SCouleur et forme :SolidMasse moléculaire :480.63ALPK1-IN-2
CAS :<p>ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).</p>Formule :C20H18F2N4O2SCouleur et forme :SolidMasse moléculaire :416.44ALPK1-IN-3
CAS :<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Formule :C20H16F2N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.43
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