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Immunologie et Inflammation

Immunologie et Inflammation

Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.

Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"

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3035 produits trouvés pour "Immunologie et Inflammation"

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  • 3-(3-Methoxyphenyl)acrylic acid

    CAS :
    <p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>
    Formule :C10H10O3
    Degré de pureté :99.91%
    Couleur et forme :Solid
    Masse moléculaire :178.19
  • Pterisolic acid B


    <p>Pterisolic acid B is a useful organic compound for research related to life sciences and the catalog number is T125924.</p>
    Formule :C20H26O4
    Couleur et forme :Solid
    Masse moléculaire :330.424
  • TPNA10168

    CAS :
    <p>Compound Fr13590, with CAS No. 957942-34-6, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13590 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Formule :C9H9ClO2S2
    Couleur et forme :Solid
    Masse moléculaire :248.75
  • Dithianon

    CAS :
    <p>Dithianon: broad-spectrum anthraquinone fungicide; sticks to leaves/fruits; controls various fungi in some produce.</p>
    Formule :C14H4N2O2S2
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :296.32
  • MJ210


    <p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>
    Couleur et forme :Odour Solid
  • iNOs-IN-6


    <p>iNOs-IN-6 is an anti-inflammatory agent known for inhibiting the expression of NF-κB, iNOS, and MAPK with an IC50 ranging from 0.2 to 0.62 μM. Additionally, it decreases the levels of pro-inflammatory mediators, such as IL-6, TNF-α, and IL-1β, with an IC50 ranging from 0.4 to 0.69 μM.</p>
    Couleur et forme :Odour Solid
  • NLRP3-IN-49


    <p>NLRP3-IN-49 (compound Z48) is a potent and specific inhibitor of NLRP3, displaying IC50 values of 0.26 μM in THP-1 cells and 0.21 μM in mouse bone marrow-derived macrophages. It directly binds to the NLRP3 protein with a dissociation constant (Kd) of 1.05 μM, effectively preventing the assembly and activation of the NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 is utilized in the research of inflammatory bowel disease.</p>
    Couleur et forme :Odour Solid
  • NOD1/2-IN-1


    <p>NOD1/2-IN-1 (Compound 18) is a potent RIPK2 inhibitor, demonstrating an IC50 value of 1.4 nM in the ADP-Glo assay. It blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathway (IC50 values are 18 nM and 170 nM for NOD1 and NOD2, respectively), thereby reducing inflammatory responses. This compound is utilized in research related to colitis.</p>
    Couleur et forme :Odour Solid
  • Isoxaben

    CAS :
    <p>Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into</p>
    Formule :C18H24N2O4
    Degré de pureté :98.84%
    Couleur et forme :Solid
    Masse moléculaire :332.39
  • diABZI-4

    CAS :
    <p>DiABZI-4 is an orally active STING agonist that exhibits broad-spectrum antiviral activity. It functions by activating STING to induce the production of pro-inflammatory cytokines and activation of lymphocytes. This action inhibits the replication of Influenza A virus (IAV), SARS-CoV-2, and Human Rhinovirus (HRV), with an EC50 range of 11.8-199 nM.</p>
    Formule :C40H51Cl2N13O6
    Couleur et forme :Solid
    Masse moléculaire :880.82
  • PROTAC IRAK4 degrader-2

    CAS :
    <p>PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.</p>
    Formule :C57H68FN11O8S
    Couleur et forme :Solid
    Masse moléculaire :1086.28
  • Tri(TLR4-IN-C34-C2-amide-C3-amide-PEG1)-amide-C3-COOH


    <p>Tri(TLR4-IN-C34) linker reduces inflammation by inhibiting TLR4 in cells, shown effective in mouse endotoxemia and enterocolitis.</p>
    Formule :C84H134N10O39
    Couleur et forme :Solid
    Masse moléculaire :1908.01
  • Amaroswerin

    CAS :
    <p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>
    Formule :C29H30O14
    Couleur et forme :Solid
    Masse moléculaire :602.54
  • Sirtuin modulator 2

    CAS :
    <p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>
    Formule :C19H15N3O2S
    Degré de pureté :99.67%
    Couleur et forme :Solid
    Masse moléculaire :349.41
  • NLRP3-IN-75


    <p>NLRP3-IN-75 is an orally effective inhibitor of NLRP3, capable of suppressing IL-1β secretion with an IC50 of 23 nM. It selectively inhibits NLRP3 activation by disrupting inflammasome assembly without affecting the assembly of NLRC4 or AIM2 inflammasomes. NLRP3-IN-75 demonstrates excellent anti-inflammatory effects in models of acute peritonitis, diabetic nephropathy, and inflammatory bowel disease (IBD).</p>
    Couleur et forme :Odour Solid
  • AM-103 Free Acid

    CAS :
    <p>AM-103 Free Acid is a bio-active chemical.</p>
    Formule :C36H39N3O4S
    Couleur et forme :Solid
    Masse moléculaire :609.78
  • ADP-β-S trisodium


    <p>ADP-β-S (trisodium) is an analog of ADP and acts as a partial agonist. It can induce human platelet aggregation and inhibit PGE1-stimulated adenylate cyclase.</p>
    Formule :C10H12N5Na3O9P2S
    Couleur et forme :Solid
    Masse moléculaire :508.95241
  • Butan-1-amine hydrochloride

    CAS :
    <p>1-Butylamine hydrochloride,butylamine, a potential agonist of Nrf2/ARE (Nuclear Factor Erythroid 2 Associated Factor 2/Antioxidant Response Element).</p>
    Formule :C4H12ClN
    Couleur et forme :Solid
    Masse moléculaire :109.6
  • CAY10512

    CAS :
    <p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>
    Formule :C15H13FO
    Couleur et forme :Solid
    Masse moléculaire :228.266
  • PMX 205

    CAS :
    <p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>
    Formule :C45H62N10O6
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :839.04