Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(140 produits)
- CXCR(153 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(109 produits)
- IκB/IKK(58 produits)
- LTR(2 produits)
- MALT(24 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(446 produits)
- NOD(17 produits)
- NOS(62 produits)
- Nrf2(82 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(59 produits)
- TLR(74 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3244 produits trouvés pour "Immunologie et Inflammation"
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Modakafusp alfa
CAS :Modakafusp alfa (TAK-573): Humanized anti-CD38 monoclonal antibody with IFNα2b for multiple myeloma research.Couleur et forme :LiquidSTING agonist-17
CAS :STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.Formule :C43H53N13O8Couleur et forme :SolidMasse moléculaire :879.96R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formule :C22H19N3O2S2Couleur et forme :SolidMasse moléculaire :421.54CRX 527
CAS :<p>CRX 527 is a TLR4 ligand and serves as an adjuvant for peptide cancer vaccines, enhancing anti-tumor immune responses. CRX 527 also induces hematopoietic stem cell (HSC) differentiation, increasing the proportion and number of LSK cells, and promotes their differentiation into macrophages. This activation bolsters immune defense and protects intestinal epithelium from radiation damage.</p>Formule :C81H151N2O19PCouleur et forme :SolidMasse moléculaire :1488.04Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Formule :C24H23N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.557-O-Methylaloeasinol
CAS :7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.Formule :C20H26O9Couleur et forme :SolidMasse moléculaire :410.419SN50
CAS :<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Formule :C129H230N36O29SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :2781.5Melredableukin alfa
CAS :Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.Couleur et forme :LiquidPMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06Neuroprotective agent 5
<p>Neuroprotective agent 5 (compound 28) acts as a brain-penetrating agent with anti-neuroinflammatory, antioxidant, and neuroprotective properties. It exhibits potent inhibition of nitric oxide (NO) with an EC50 of 0.49 μM and suppresses the release of pro-inflammatory mediators PGE2 and TNF-α. Additionally, it downregulates the expression of iNOS and COX-2 proteins, facilitating the polarization of BV-2 cells from a pro-inflammatory M1 phenotype to an anti-inflammatory M2 phenotype. Neuroprotective agent 5 also dose-dependently inhibits acetylcholinesterase (AChE) activity and the aggregation of Aβ42. This compound is useful for research into Alzheimer's disease.</p>Couleur et forme :Odour SolidSIN 14
<p>SIN 14 is an HO-1 activator that targets and activates HO-1 through an allosteric mechanism. Additionally, SIN 14 can induce the polarization of macrophages from the M1 phenotype to the M2 phenotype.</p>Formule :C20H22ClNO4Couleur et forme :SolidMasse moléculaire :375.12374BRD5075
BRD5075 is an effective activator of GPR65, stimulating the production of cAMP in a GPR65-dependent manner. Additionally, it reduces the gene expression of IL-1, IL-2, TNF, and chemokines. BRD5075 holds potential for researching multiple sclerosis and inflammatory bowel disease (IBD).Couleur et forme :Odour SolidFM-303
<p>FM-303 is a monoclonal antibody inhibitor that targets interleukin-23 (IL-23). It shows promise for research in immune system and digestive system diseases.</p>Couleur et forme :Odour LiquidTLR7 agonist 17
CAS :TLR7 agonist 17 (compound 20) functions as a highly effective TLR7 agonist, exhibiting EC 50 values of 12 nM for hTLR7 and 17 nM for mTLR7. Additionally, this compound has demonstrated anticancer activity [1].Formule :C25H37N7O3Couleur et forme :SolidMasse moléculaire :483.61PROTAC IRAK4 degrader-2
CAS :<p>PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.</p>Formule :C57H68FN11O8SCouleur et forme :SolidMasse moléculaire :1086.28CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Formule :C28H28N2O6SCouleur et forme :SolidMasse moléculaire :520.6Dihydrorhodamine 6G
CAS :DHR 6G, nonfluorescent reduced Rhodamine 6G, permeates cells, indicating ROS by oxidizing to fluorescent form in mitochondria.Formule :C28H32N2O3Couleur et forme :SolidMasse moléculaire :444.57NF-κB-IN-9
NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dualFormule :C62H50N4O4SCouleur et forme :SolidMasse moléculaire :947.15Clazakizumab
CAS :<p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>Couleur et forme :LiquidPROTAC STING Degrader-2
CAS :<p>PROTAC STING Degrader-2 is a protein degrader targeting the Stimulator of interferon genes (STING) with a DC50 of 0.53 μM. It induces STING protein degradation by covalently binding to both the STING protein and an E3 ubiquitin ligase. This compound is useful for studying the role of STING in autoinflammatory and autoimmune diseases.</p>Formule :C74H79FN10O15S3Couleur et forme :SolidMasse moléculaire :1463.67
