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Immunologie et Inflammation

Immunologie et Inflammation

Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.

Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"

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3035 produits trouvés pour "Immunologie et Inflammation"

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  • BR102910 

    CAS :
    <p>BR102910: Selective FAP inhibitor, features 4-thiazolecarboxamide with cyano-difluoro-pyrrolidine and dichlorophenyl elements.</p>
    Formule :C18H14Cl2F2N4O2S
    Degré de pureté :97%
    Couleur et forme :Solid
    Masse moléculaire :459.3
  • ENUM006


    <p>ENUM006 is a human monoclonal antibody (mAb) that targets CD223/LAG3.</p>
    Couleur et forme :Odour Liquid
  • JAK-STAT Compound Library


    <p>A unique collection of 252 JAK/STAT signaling targeted compounds for high throughput and high content screening;</p>
    Couleur et forme :Odour Solid
  • Xanthine oxidase-IN-12


    <p>Xanthine oxidase-IN-12 (Compound 11), an inhibitor of xanthine oxidase (XO), possesses an IC50 value of 91 nM and exhibits antioxidant properties, additionally</p>
    Degré de pureté :98%
    Couleur et forme :Odour Solid
  • Iromycin A

    CAS :
    <p>Iromycin A: a bacterial metabolite inhibiting NOS III over NOS I, blocks NADH oxidation, IC50 = 0.461 µM.</p>
    Formule :C19H29NO2
    Couleur et forme :Solid
    Masse moléculaire :303.44
  • Histamine & Melatonin Receptor-Targeted Compound Library


    <p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>
    Couleur et forme :Odour Solid
  • Biotin-labeled ODN 1018 sodium


    <p>Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through</p>
    Couleur et forme :Odour Solid
  • Guignardone L

    CAS :
    <p>Guignardone L, a metabolite extracted from the endophytic fungus Guignardia mangiferae, possesses toll-like receptor 3 (TLR3) regulating activity [1].</p>
    Formule :C17H24O4
    Couleur et forme :Solid
    Masse moléculaire :292.37
  • NLRP3-IN-12


    <p>NLRP3-IN-12 inhibits NLRP3 inflammasome, curbing IL-1β release with 0.45 μM IC50, for inflammatory bowel disease research.</p>
    Formule :C27H32ClNO7
    Couleur et forme :Solid
    Masse moléculaire :518
  • IL-17A inhibitor 2

    CAS :
    <p>IL-17A inhibitor 2 is an IL-17A inhibitor for treating psoriasis, rheumatoid arthritis, and multiple sclerosis.</p>
    Formule :C24H25F7N8O4
    Couleur et forme :Solid
    Masse moléculaire :622.505
  • Ziltivekimab

    CAS :
    <p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>
    Degré de pureté :95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)
    Couleur et forme :Soild
  • Tetrachlorohydroquinone

    CAS :
    <p>TCHQ, a pentachlorophenol metabolite, toxic to trout liver cells, increases ROS, disrupts mitochondria, and causes necrosis in splenocytes. EC50: 1.55 μM.</p>
    Formule :C6H2Cl4O2
    Couleur et forme :Solid
    Masse moléculaire :247.89
  • Inhibitor Library


    <p>A unique collection of 8328 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>
    Couleur et forme :Odour Solid
  • JAB-BX102


    <p>JAB-BX102 is a human monoclonal antibody (mAb) that targets NT5E/CD73. It is applicable in research studies involving breast cancer, pancreatic cancer, prostate cancer, and other cancers.</p>
    Couleur et forme :Odour Liquid
  • C6 L-threo Ceramide (d18:1/6:0)

    CAS :
    <p>C6 L-threo Ceramide: bioactive sphingolipid, cytotoxic to U937 cells (IC50=18μM), non-metabolic, boosts IL-4 in T cells at 10μM.</p>
    Formule :C24H47NO3
    Couleur et forme :Solid
    Masse moléculaire :397.63
  • Post-Translational Modification Compound Library


    <p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>
    Couleur et forme :Odour Solid
  • Nonsteroidal Anti-Inflammatory Compound Library


    <p>xnum non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.</p>
    Couleur et forme :Odour Solid
  • Transcription Factor-Targeted Compound Library


    <p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>
    Couleur et forme :Odour Solid
  • Pyroptosis Compound Library


    <p>xnum types of active small molecules associated with pyroptosis for high-throughput and high-content screening.</p>
    Couleur et forme :Liquid
  • NF-κB-IN-9


    <p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>
    Formule :C62H50N4O4S
    Couleur et forme :Solid
    Masse moléculaire :947.15
  • FITC-labeled ODN 1585 sodium


    <p>FITC-labeled ODN 1585 (sodium) effectively induces IFN and TNFα production and serves to assess CpG ODN cellular uptake and localization through confocal laser-</p>
    Couleur et forme :Odour Solid
  • Chemokine Inhibitor Library


    <p>A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;</p>
    Couleur et forme :Odour Solid
  • Sericin


    <p>Sericin is a globular protein isolated from silkworm cocoons. It has cognitive enhancement and pain-relieving properties. Additionally, Sericin serves as a cryoprotectant, potentially replacing fetal bovine serum or dimethyl sulfoxide (DMSO). It helps reduce oxidative stress and reactive oxygen species (ROS). Sericin aids in wound repair by promoting collagen production and exhibits activities such as antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, moisturizing, wound healing promotion, antibacterial, and antitumor effects.</p>
    Couleur et forme :Odour Solid
  • Immunology/Inflammation Compound Library


    <p>A unique collection of xnum anti-inflammation compounds effective for high throughput screening and high content screening.</p>
    Couleur et forme :Odour Solid
  • Anti-PSMA Antibody


    <p>Anti-PSMA Antibody is a humanized IgG1 monoclonal antibody targeting PSMA. It serves as the antibody component of the ADC molecule ARX517.</p>
    Couleur et forme :Odour Liquid
  • PMX 205 Trifluoroacetate


    <p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>
    Formule :C47H63F3N10O8
    Couleur et forme :Solid
    Masse moléculaire :953.06
  • Fletikumab

    CAS :
    <p>Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid</p>
    Degré de pureté :100% (SEC-HPLC) - > 95%
    Couleur et forme :Liquid
    Masse moléculaire :146.48 kDa
  • AMG-424


    <p>AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 and CD3E. It effectively kills cancer cells that express CD38, stimulates T cell proliferation, and reduces cytokine release. AMG-424 exhibits antitumor activity in mouse cancer models with bone marrow invasion and induces peripheral B cell depletion in cynomolgus monkeys. It is used in studies of multiple myeloma. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3.</p>
    Couleur et forme :Odour Liquid
  • GPCR Compound Library


    <p>A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target</p>
    Couleur et forme :Odour Solid
  • Deacetylgedunin

    CAS :
    <p>Deacetylgedunin is a limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica.</p>
    Formule :C26H32O6
    Couleur et forme :Solid
    Masse moléculaire :440.53
  • KL-A289


    <p>KL-A289 is a human monoclonal antibody (mAb) that targets CD223/LAG3. It can be utilized in research related to metastatic gastric cancer.</p>
    Couleur et forme :Odour Liquid
  • Ginger extract

    CAS :
    <p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>
    Couleur et forme :Solid
  • Carotuximab

    CAS :
    <p>Carotuximab (DE-122), an antibody, inhibits CD105 to reduce angiogenesis, inflammation, and tumor growth.</p>
    Degré de pureté :> 95%
    Couleur et forme :Liquid
    Masse moléculaire :144.8 kDa
  • Daclizumab

    CAS :
    <p>Daclizumab (Zenapax), a humanized antibody, blocks IL-2 by targeting CD25, used in multiple sclerosis.</p>
    Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%
    Couleur et forme :Liquid
    Masse moléculaire :144.12 kDa
  • IMP-761


    <p>IMP-761 is a human IgG4 monoclonal antibody (mAb) that targets CD223/LAG3. It binds to the D1 domain of human LAG32. The recommended isotype control is Human IgG4 kappa, Isotype Control.</p>
    Couleur et forme :Odour Liquid
  • DNV-3


    <p>DNV-3 is a human monoclonal antibody (mAb) that targets CD223/LAG3.</p>
    Couleur et forme :Odour Liquid
  • STING agonist-17

    CAS :
    <p>STING agonist-17 (compound 4a) is a highly potent stimulator of the STING pathway, exhibiting an IC 50 of 0.062 nM.</p>
    Formule :C43H53N13O8
    Couleur et forme :Solid
    Masse moléculaire :879.96
  • IPH5301


    <p>IPH5301 is a human IgG1 monoclonal antibody (mAb) that targets NT5E/CD73. It features a functionally silenced Fc domain and specifically inhibits the enzymatic activity of both soluble and membrane-bound CD73, thereby restoring the proliferation of immune T cells. IPH5301 is applicable for research in anti-tumor immunotherapy. Recommended isotype control: HumanIgG1kappa, Isotype Control.</p>
    Couleur et forme :Odour Liquid
  • Siegesbeckialide I


    <p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>
    Formule :C20H28O6
    Couleur et forme :Solid
    Masse moléculaire :364.43
  • Biotin-labeled ODN 1668 sodium


    <p>Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>
    Couleur et forme :Odour Solid
  • NLRP3-IN-14

    CAS :
    <p>NLRP3-IN-14, potent selective NLRP3 inhibitor, KD 5.87μM; IC50 0.131μM for IL-1β; for inflammation research.</p>
    Formule :C27H28N2O4
    Couleur et forme :Solid
    Masse moléculaire :444.52
  • Pascolizumab

    CAS :
    <p>Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis.</p>
    Degré de pureté :> 95%
    Couleur et forme :Liquid
    Masse moléculaire :147.18 kDa
  • NVP-DKY709

    CAS :
    <p>NVP-DKY709 is a potent IKZF2 inhibitor for the treatment of cancers.</p>
    Formule :C25H27N3O3
    Degré de pureté :99%
    Couleur et forme :Solid
    Masse moléculaire :417.5
  • Romilkimab

    CAS :
    <p>Romilkimab (SAR156597) is a chimeric humanized immunoglobulin (Ig) antibody designed to specifically target interleukins 4 and 13 (IL-4 and IL-13) [1].</p>
    Couleur et forme :Liquid
  • FITC-labeled ODN 1018 sodium


    <p>FITC-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, facilitates the assessment of CpG ODN cellular uptake and localization through confocal</p>
    Couleur et forme :Solid
    Masse moléculaire :8171
  • Basiliximab

    CAS :
    <p>Basiliximab: chimeric IgG1 antibody inhibiting interleukin-2 receptor, used for kidney transplant immunosuppression.</p>
    Degré de pureté :SDS-PAGE:94.1%;SEC-HPLC:95.3%
    Couleur et forme :Liquid
    Masse moléculaire :144.01 kDa
  • Cyclo(L-Pro-L-Val)

    CAS :
    <p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>
    Formule :C10H16N2O2
    Degré de pureté :98.18%
    Couleur et forme :Solid
    Masse moléculaire :196.25
  • Mifamurtide sodium

    CAS :
    <p>Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.</p>
    Formule :C59H108N6NaO19P
    Degré de pureté :98%
    Couleur et forme :Solid
    Masse moléculaire :1259.48
  • Clazakizumab

    CAS :
    <p>Clazakizumab: monoclonal antibody targeting IL-6, may inhibit COVID-19 cytokine response, researched for PsA and renal rejection.</p>
    Couleur et forme :Liquid
  • Diprovocim-1

    CAS :
    <p>Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 &amp; CTLs against tumors with anti-PD-L1 in mice.</p>
    Formule :C56H56N6O6
    Couleur et forme :Solid
    Masse moléculaire :909.1