Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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GPCR Compound Library
<p>A unique collection of xnum GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target</p>Couleur et forme :Odour SolidDeacetylgedunin
CAS :<p>Deacetylgedunin is a limonoid that is the 7-deacetyl derivative of gedunin. It has been isolated from Azadirachta indica.</p>Formule :C26H32O6Couleur et forme :SolidMasse moléculaire :440.53HNW005
<p>HNW005 is a dual inhibitor targeting the NLRP3 inflammasome and urate transporter 1 (URAT1). It exhibits an inhibition constant (KD) of 204.6 nM and an IC50 of 1.7 μM for NLRP3 inflammasome activation, while demonstrating an IC50 of 6.4 μM for inhibiting uric acid transmembrane transport. At an administered dose of 2 mg/kg in vivo, HNW005 achieves a uric acid reduction rate of 64.8%, effectively providing anti-inflammatory, analgesic, and urate-lowering effects by inhibiting NLRP3 inflammasome activation and uric acid transport. HNW005 is applicable for research in gouty arthritis.</p>Couleur et forme :Odour SolidFletikumab
CAS :<p>Fletikumab (NNC0109-0012) is a monoclonal antibody against IL-20 that is often used as an IL-20 inhibitor.Fletikumab is used in the study of rheumatoid</p>Degré de pureté :100% (SEC-HPLC) - > 95%Couleur et forme :LiquidMasse moléculaire :146.48 kDaGuretolimod hydrochloride
<p>Guretolimod hydrochloride acts as an agonist for Toll-like receptor 7 (TLR7) [1].</p>Formule :C24H35ClF3N5O4Couleur et forme :SolidMasse moléculaire :550.01MAPK-IN-4
<p>MAPK-IN-4 (Compound c1) is an orally active anti-inflammatory agent that inhibits the expression and release of pro-inflammatory cytokines IL-6 and TNF-α induced by LPS. It interacts with IRAK4 to exert its anti-inflammatory effects by inhibiting the MAPK pathway.</p>Couleur et forme :Odour SolidEftilagimod alfa
CAS :<p>Eftilagimod alfa (IMP321), a recombinant LAG-3Ig fusion protein, binds to MHC class II and mediates the activation of antigen-presenting cells (APCs), which in</p>Couleur et forme :LiquidAnti-PSMA Antibody
<p>Anti-PSMA Antibody is a humanized IgG1 monoclonal antibody targeting PSMA. It serves as the antibody component of the ADC molecule ARX517.</p>Couleur et forme :Odour LiquidImmunology/Inflammation Compound Library
<p>A unique collection of xnum anti-inflammation compounds effective for high throughput screening and high content screening.</p>Couleur et forme :Odour SolidMTvkPABC-P5
<p>MTvkPABC-P5d, functioning as a TLR7 agonist, serves as an immune stimulant and is utilized in the synthesis of immune-stimulating antibody conjugates (ISACs) [1</p>Formule :C52H73N11O14Couleur et forme :SolidMasse moléculaire :1076.2SN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Formule :C129H230N36O29S·XCF3COOHCouleur et forme :SolidMasse moléculaire :2781.5 (free base)HPPD-IN-1
<p>HPPD-IN-1 (compound II-3), a potent HPPD inhibitor, exhibits inhibitory activity against Arabidopsis thaliana HPPD (AtHPPD) with an IC50 of 0.248 μM, surpassing</p>Formule :C12H6F3NO4Couleur et forme :SolidMasse moléculaire :285.18Rucosopasem manganese
CAS :<p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>Formule :C27H45MnN5O4Couleur et forme :SolidMasse moléculaire :558.626Melredableukin alfa
CAS :<p>Melredableukin alfa, a human IgG1-κ fused with IL2 mutein, is studied for autoimmune hepatitis and ulcerative colitis.</p>Couleur et forme :LiquidSacituzumab tirumotecan
CAS :<p>Sacituzumab tirumotecan (SKB264) is an antibody-drug conjugate (ADC) targeting TROP2 (trophoblast cell surface antigen 2), capable of releasing the active payload KL610023 within TROP2-positive tumour cells. an effective topoisomerase I inhibitor that induces DNA damage and leads to cell cycle arrest and apoptosis, for use in non-small cell lung cancer (NSCLC) and triple-negative breast cancer (TNBC).</p>Degré de pureté :99%Couleur et forme :LiquidPyroptosis Compound Library
<p>xnum types of active small molecules associated with pyroptosis for high-throughput and high-content screening.</p>Couleur et forme :LiquidTranscription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Couleur et forme :Odour SolidKeap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Couleur et forme :Odour SolidNonsteroidal Anti-Inflammatory Compound Library
<p>xnum non-steroidal anti-inflammatory compounds for high-throughput and high-content screening.</p>Couleur et forme :Odour SolidHNGF6A
CAS :<p>increases glucose stimulated insulin secretion and glucose metabolism</p>Formule :C112H198N34O31S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2581.11Biotin-labeled ODN 1018 sodium
<p>Biotin-labeled ODN 1018 (sodium), a TLR-9 agonist oligodeoxynucleotide, serves as a tool for assessing cellular uptake and localization of CpG ODNs through</p>Couleur et forme :Odour SolidPost-Translational Modification Compound Library
<p>Contains xnum active small molecules for research related to post-translational modifications (PTMs);</p>Couleur et forme :Odour SolidPIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Formule :C71H123N19O21S2·xC2HF3O2Couleur et forme :SolidhCYP1B1-IN-1
<p>hCYP1B1-IN-1 (compound B18) is an inhibitor of hCYP1B1 with an IC50 value of 3.6 nM and also acts as an antagonist of the Aryl Hydrocarbon Receptor.</p>Formule :C18H14ClF3O3Couleur et forme :SolidMasse moléculaire :370.75JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Formule :C45H73N3O13Couleur et forme :SolidMasse moléculaire :864.073Anti-inflammatory agent 59
<p>Anti-inflammatory agent 58 is characterized by its ability to inhibit IL-1β with an IC50 value of 2.28 μM.</p>Couleur et forme :Odour SolidProstaglandin D synthase
CAS :<p>Prostaglandin D synthase is a biomarker for meningioma cells and coronary artery disease. Lipocalin-type prostaglandin D synthase (L-PGDS) is found in human coronary atherosclerotic plaques and can be detected in human serum.</p>Couleur et forme :SolidL-156,602
CAS :<p>L-156,602 has a wide range of applications in life science related research.</p>Formule :C38H64N8O13Couleur et forme :SolidMasse moléculaire :840.973Ziltivekimab
CAS :<p>Ziltivekimab (MEDI 5117) is a CHO-expressed humanized monoclonal antibody targeting IL-6/IFNb2 for use in immune system diseases.</p>Degré de pureté :95% - 97.9% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :SoildDovanvetmab
CAS :<p>Dovanvetmab (ZTS-00521505) is an IgG1-κ monoclonal antibody that targets feline interleukin 31 (Felcat IL31), primarily produced in Chinese Hamster Ovary (CHO)</p>Couleur et forme :LiquidSDH-IN-23
<p>SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.</p>Formule :C19H11ClF6N2O2Couleur et forme :SolidMasse moléculaire :448.75IKZF-IN-1
<p>IKZF-IN-1 (Compound I) is a molecular glue that degrades the karos zinc finger family proteins (IKZF) IKZF 1/2/3/4 and is used as an immune modulator in cancer and viral infection research.</p>Formule :C26H28FN5O4Couleur et forme :SolidMasse moléculaire :493.53Modakafusp alfa
CAS :<p>Modakafusp alfa (TAK-573): Humanized anti-CD38 monoclonal antibody with IFNα2b for multiple myeloma research.</p>Couleur et forme :LiquidPROTAC IRAK4 degrader-3
CAS :<p>PROTAC IRAK4 degrader-3 is a PROTAC-induced IRAK4 degrader based on von Hippel-Lindau.</p>Formule :C57H68FN11O8SCouleur et forme :SolidMasse moléculaire :1086.3Endoplasmic Reticulum Stress Compound Library
<p>A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);</p>Couleur et forme :Odour SolidArginase inhibitor 9
<p>Arginase inhibitor9 (Compound 12a) is a type of arginase enzyme inhibitor with IC50 values of 9 μM for bovine and 55 μM for human arginase I. It also exhibits antioxidant activity by scavenging free radicals. Moreover, Arginase inhibitor9 effectively regulates collagen and procollagen levels, thereby exerting an anti-fibrotic effect.</p>Formule :C13H11NO4SCouleur et forme :SolidMasse moléculaire :277.38-Nitroguanine
CAS :<p>8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant</p>Formule :C5H4N6O3Couleur et forme :SolidMasse moléculaire :196.12IL-1β-IN-1
CAS :<p>IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].</p>Formule :C22H34O2Couleur et forme :SolidMasse moléculaire :330.5Nuclear Receptor Compound Library
<p>A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;</p>Couleur et forme :Odour SolidENUM006
<p>ENUM006 is a human monoclonal antibody (mAb) that targets CD223/LAG3.</p>Couleur et forme :Odour LiquidDOPAL
CAS :<p>DOPAL, a neurotoxic aldehyde from dopamine metabolism, is linked to Parkinson's and can convert to DOPAC or DOPET.</p>Formule :C8H8O3Couleur et forme :SolidMasse moléculaire :152.15Nasunin
CAS :<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formule :C42H47ClO23Couleur et forme :SolidMasse moléculaire :955.26Isuventatug
CAS :<p>Isuventatug is a monoclonal antibody that targets human MICA (MHC I chain-related molecule A) and MICB (MHC I chain-related molecule B). By binding to MICA and MICB, Isuventatug modulates the interaction between immune cells and tumor cells, exhibiting anti-tumor activity. This compound holds potential for research in cancer immunotherapy.</p>Couleur et forme :LiquidMyD88-IN-1
CAS :<p>MyD88-IN-1: Potent MyD88 inhibitor with anti-inflammatory effects, blocking NF-κB and TLR/IL-1 pathways; potential for cancer and inflammation treatment.</p>Formule :C23H24N6O7SDegré de pureté :>99.99%Couleur et forme :SoildMasse moléculaire :528.54Fraxinellone analog 1
<p>Fraxinellone analog 1 (compound 2) is an effective and rapid activator of the Nrf2-mediated antioxidative defense system, providing protection against glutamate-mediated excitotoxicity. It induces the expression of antioxidative genes Gpx4, Sod1, and Nqo1. Additionally, Fraxinellone analog 1 exerts neuroprotective effects and modulates oxidative stress and inflammation, making it suitable for research on neurodegenerative diseases.</p>Couleur et forme :Odour Solid(±)11(12)-EET
CAS :<p>(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higher</p>Formule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47Lemnalol
CAS :<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formule :C15H24ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.35Kinase Inhibitor Library
<p>A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;</p>Couleur et forme :Odour SolidExosome Compound Library
<p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>Couleur et forme :Odour SolidODN 2395
CAS :<p>ODN 2395, a class C oligodeoxynucleotide and TLR9 agonist, serves as a vaccine adjuvant. Its sequence is 5'-tcgtcgttttcggcgc:gcgccg-3' [1].</p>Couleur et forme :SolidMasse moléculaire :7035
