Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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FITC-labeled ODN 1826 sodium
<p>FITC-labeled ODN 1826 (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of CpG ODN cellular uptake and</p>Couleur et forme :Odour Solid6-Amyl-2-pyrone
CAS :<p>6-Amyl-2-pyrone exhibits inhibitory activity against tyrosinase, antibacterial and antiviral activity against Penicillium vulpinum and Aspergillus flavus, and antifungal activity against Sclerotinia sp.</p>Formule :C10H14O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :166.22NG-Hydroxy-L-arginine acetate
CAS :<p>NG-Hydroxy-L-arginine acetate (NOHA acetate) acts as a crucial physiological inhibitor of arginase, playing a vital role in the conversion of arginine to nitric oxide and citrulline via nitric oxide synthase.</p>Formule :C6H14N4O3xC2H4O2Couleur et forme :SolidMasse moléculaire :190.20（free base）Licoagrochalcone C
CAS :<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Formule :C21H22O5Couleur et forme :SolidMasse moléculaire :354.4NLRP3-IN-48
<p>NLRP3-IN-48 is an inhibitor of NLRP3. It suppresses the activation of the NLRP3 inflammasome by targeting the NLRP3 protein, thereby interfering with the assembly of the NLRP3 inflammasome. Additionally, NLRP3-IN-48 exhibits anti-inflammatory activity in a DSS-induced acute colitis model in mice.</p>Couleur et forme :Odour SolidMosnodenvir
CAS :<p>Mosnodenvir is a pan-DENV inhibitor effective against all four serotypes of dengue viruses, with the advantage of being highly potent and orally bioavailable, and blocks viral replication by inhibiting the formation of the complex between NS3 and NS4B.</p>Formule :C26H22ClF3N2O6SDegré de pureté :99.72%Couleur et forme :SoildMasse moléculaire :582.98BMS-986179
<p>BMS-986179 is a human monoclonal antibody targeting NT5E/CD73. It inhibits CD73 enzymatic activity both in tumor vasculature and tumor cells. BMS-986179 is applicable for research in advanced solid tumors.</p>Couleur et forme :Odour LiquidBAY-069
CAS :<p>BAY-069 blocks BCAT1 (IC50:31 nM) & BCAT2 (IC50:153 nM), useful for cancer research.</p>Formule :C22H14ClF3N2O3Degré de pureté :99.58%Couleur et forme :SoildMasse moléculaire :446.81GSK2831781
<p>GSK2831781 is a human IgG1 monoclonal antibody (mAb) designed to target CD223/LAG3. This compound is applicable in research studies focused on ulcerative colitis. For experimental controls, the recommended isotype control is Human IgG1 kappa.</p>Couleur et forme :Odour LiquidInbakicept
CAS :<p>Inbakicept (ALT 803) is a fusion protein of the IL-15 receptor 伪-sushi binding domain IL-15R伪Su and immunoglobulin G1 (human Fc fragment).</p>Degré de pureté :98.94%Couleur et forme :LiquidMUC1, mucin core
CAS :<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Formule :C61H101N19O24Couleur et forme :SolidMasse moléculaire :1484.588Anti-inflammatory agent 64
<p>Anti-inflammatory agent 64 (compound 4b) exhibits antioxidant and anti-inflammatory activities, effectively inhibiting the secretion of IL-6 and TNF-α while</p>Degré de pureté :98%Couleur et forme :Odour SolidRucosopasem manganese
CAS :<p>Rucosopasem manganese (GC4711), a selective SOD mimetic, converts superoxide to peroxide for cancer research.</p>Formule :C27H45MnN5O4Couleur et forme :SolidMasse moléculaire :558.626Keap1-Nrf2-IN-27
<p>Keap1-Nrf2-IN-27 is an inhibitor of the Keap1-Nrf2 protein-protein interaction (PPI) with a KD2 value of 0.119 μM. It suppresses the expression of pro-inflammatory cytokines TNF-α and IL-6 in an LPS-induced RAW264.7 cell model.</p>Couleur et forme :Odour SolidiE-DAP dihydrochloride
<p>iE-DAP dihydrochloride is a Nod1 agonist that activates the NF-κB pathway through recognition by Nod1, leading to an inflammatory cytokine response. This compound is useful for studying maternal-fetal inflammation and preterm birth.</p>Formule :C12H23Cl2N3O7Couleur et forme :SolidMasse moléculaire :391.09131AMY-101
CAS :<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Formule :C83H117N23O18S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1789.111-Ethoxycarbonyl-β-carboline
CAS :<p>1-Ethoxycarbonyl-β-carboline is a natural product for research related to life sciences. The catalog number is TN7072 and the CAS number is 72755-19-2.</p>Formule :C28H23N4O4Couleur et forme :SolidMasse moléculaire :479.516Allyl methyl trisulfide
CAS :<p>Allyl methyl trisulfide: a garlic oil compound with antibacterial, antioxidant, and antitumor properties.</p>Formule :C4H8S3Couleur et forme :SolidMasse moléculaire :152.3NOX4-IN-1
<p>NOX4-IN-1 (Compound 14m) is an inhibitor of NADPH oxidase 4 (NOX4) that reduces the production of reactive oxygen species (ROS). It also inhibits the TGF-β1/Smad signaling pathway, leading to decreased expression of fibrosis-related proteins. Additionally, NOX4-IN-1 impedes the migration of NRK-49F cells.</p>Formule :C26H16ClN3O3Couleur et forme :SolidMasse moléculaire :453.877Paneolilludinic acid
CAS :<p>Paneolilludinic acid from Cryptomarasmius aucubae fungus inhibits NO production.</p>Formule :C15H22O3Couleur et forme :SolidMasse moléculaire :250.33Polyinosinic acid
CAS :<p>Polyinosinic acid: single-strand, TLR3 agonist, boosts immune response, has immune regulation uses.</p>Formule :(C10H13N4O8P)xCouleur et forme :SolidSirtuin modulator 2
CAS :<p>Sirtuin modulator 2 (N-(3-(imidazo[2,1-b]thiazol-6-yl)phenyl)-2-methoxybenzamide) exhibits antidiabetic, anti-inflammatory and antitumor activities.</p>Formule :C19H15N3O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :349.41PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Formule :C47H63F3N10O8Couleur et forme :SolidMasse moléculaire :953.06Arginase inhibitor 7
CAS :<p>Arginase Inhibitor 7 (compound A17), an inhibitor of arginase (ARG1), exhibits an IC 50 value of 0.16 μM and possesses high oral bioavailability [1].</p>Formule :C14H29BN6O5Couleur et forme :SolidMasse moléculaire :372.23Bivalirudin TFA
CAS :<p>Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.</p>Formule :C98H138N24O33·C2HF3O2Couleur et forme :SolidMasse moléculaire :2294.34KYN-101
CAS :<p>KYN-101 is an and aryl hydrocarbon receptor (AHR) inhibitor with anticancer activity. KYN-101 is used for the study of breast cancer and acute myeloid leukemia.</p>Formule :C22H19FN6Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :386.43cGAMP disodium
CAS :<p>cGAMP disodium, a bacterial CDN, boosts interferon production and activates STING, enhancing immune responses as a sublingual adjuvant.</p>Formule :C20H24N10O13P2·2NaCouleur et forme :SoildMasse moléculaire :720.39SMRT peptide
CAS :<p>SMRT peptide, one of the corepressor factors interacting with the BCL6 BTB domain, binds to the BTB domain of BCL6 to enhance its transcriptional repression function. Additionally, SMRT peptide is utilized for studying protein-protein interactions.</p>Formule :C82H142N26O24Couleur et forme :SolidMasse moléculaire :1876.16Isoxaben
CAS :<p>Isoxaben (EL 107) is a specific inhibitor of cell wall biosynthesis, often used as a herbicide, that inhibits the incorporation of radiolabeled glucose into</p>Formule :C18H24N2O4Degré de pureté :98.84%Couleur et forme :SolidMasse moléculaire :332.39CAY10614
CAS :<p>CAY10614 is a TLR4 antagonist.</p>Formule :C42H78INO2Couleur et forme :SolidMasse moléculaire :755.995Phytoene desaturase-IN-1
CAS :<p>Potent PDS inhibitor with Kd of 65.9 μM, induces mRNA reduction and ROS accumulation, useful in agriculture.</p>Formule :C18H13ClF3N3O2SCouleur et forme :SolidMasse moléculaire :427.83Valeriandoid F
CAS :<p>Valeriandoid F, an iridoid, strongly inhibits NO production (IC50: 0.88 μM) and has anti-inflammatory, antiproliferative effects.</p>Formule :C23H34O9Couleur et forme :SolidMasse moléculaire :454.516NLRP3-IN-49
<p>NLRP3-IN-49 (compound Z48) is a potent and specific inhibitor of NLRP3, displaying IC50 values of 0.26 μM in THP-1 cells and 0.21 μM in mouse bone marrow-derived macrophages. It directly binds to the NLRP3 protein with a dissociation constant (Kd) of 1.05 μM, effectively preventing the assembly and activation of the NLRP3 inflammasome, thereby exhibiting anti-inflammatory properties. NLRP3-IN-49 is utilized in the research of inflammatory bowel disease.</p>Couleur et forme :Odour SolidCOX-2/15-LOX-IN-2
<p>COX-2/15-LOX-IN-2 is a potent inhibitor of both COX-2 and 15-LOX, demonstrating IC50 values of 0.065 μM for COX-2 and 1.86 μM for 15-LOX.</p>Formule :C27H26N6OS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :514.66MJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Couleur et forme :Odour SolidFeeblin
CAS :<p>Feeblin (IRF5-IN-1) induces protein degradation, inhibits pro-inflammatory pathways, and is used for autoimmune disease research.</p>Formule :C27H33N3O2Degré de pureté :99.58% - 99.88%Couleur et forme :SoildMasse moléculaire :431.57Cartap hydrochloride
CAS :<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formule :C18H33Cl2CuN3O3Couleur et forme :Colorless Crystalline Slightly Hygroscopic Solid CoaMasse moléculaire :473.93TLR4 agonist-1 TEA
<p>TLR4 agonist-1 (TEA, compound 17a) is a potent activator of Toll-like Receptor 4 (TLR4) and prompts the production of MIP-1β in RAW 264.7 and MM6 cells [1].</p>Couleur et forme :Odour SolidMCI
<p>MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation</p>Formule :C45H52ClN7O13Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :934.39CAY10657
CAS :<p>CAY10657 has a wide range of applications in life science related research.</p>Formule :C17H20N4O3SCouleur et forme :SolidMasse moléculaire :360.43NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formule :C62H50N4O4SCouleur et forme :SolidMasse moléculaire :947.15Ginger extract
CAS :<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Couleur et forme :SolidNrf2 degrader 1
CAS :<p>Nrf2 degrader 1 (compound 1), a PROTAC Nrf2 degrader, exhibits anticancer properties by inhibiting the growth of cancer cells. It demonstrates IC 50 values of 100 nM for A549 cells and 40 nM for LK-2 cells, indicating potent efficacy [1].</p>Formule :C45H42N6O8SCouleur et forme :SolidMasse moléculaire :826.92PROTAC STING Degrader-1
CAS :<p>PROTAC STING Degrader-1 (Compound SP23) is a STING-targeted PROTAC degrader exhibiting a DC50 of 3.2 μM and demonstrates anti-inflammatory activity [1].</p>Formule :C34H33N7O10Couleur et forme :SolidMasse moléculaire :699.67NF-κΒ activator 1
CAS :<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formule :C16H11FN2O2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :314.33Guignardone L
CAS :<p>Guignardone L, a metabolite extracted from the endophytic fungus Guignardia mangiferae, possesses toll-like receptor 3 (TLR3) regulating activity [1].</p>Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37IFN-γ Antagonist 1
CAS :<p>IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cells</p>Formule :C115H194N34O34SCouleur et forme :SolidMasse moléculaire :2629.04PSMA-IN-1
<p>PSMA-IN-1 (compound 23) is an inhibitor of PSMA with a Ki value of 2.49 nM. It inhibits tumor growth with high selectivity and specificity in PSMA+ tumor models. Additionally, PSMA-IN-1 serves as an NIR (λEX: 620 nm; λEM: 670 nm) dye for tumor imaging. PSMA-IN-1 is utilized in prostate cancer research.</p>Formule :C66H80N10O20Masse moléculaire :1332.55504Anti-osteoporosis agent-8
<p>Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.</p>Formule :C18H19F3N2O2SeMasse moléculaire :432.056383-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide
CAS :<p>3-(9-Chloro-3-methyl-4-oxoisoxazolo[4,3-c]quinolin-5(4H)-yl)-N-(3,4,5-trimethoxyphenyl)benzeneacetamide inhibits multidrug resistance protein (MRP1).</p>Formule :C28H24ClN3O6Degré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :533.96
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