Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(148 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(112 produits)
- IκB/IKK(60 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(444 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(79 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3045 produits trouvés pour "Immunologie et Inflammation"
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3′-Hydroxy-4′-O-methylglabridin
CAS :<p>3′-Hydroxy-4′-O-methylglabridin effectively prevents NADH-dependent peroxidation, exhibiting potent antioxidant properties [1].</p>Formule :C21H22O5Couleur et forme :SolidMasse moléculaire :354.47-Deoxy-trans-dihydronarciclasine
CAS :<p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>Formule :C14H15NO6Couleur et forme :SolidMasse moléculaire :293.27Glutathione ethyl ester acetate
<p>Glutathione ethyl ester acetate is an antioxidant and cell-permeable Glutathione (GSH) donor that restore oxidative stress and TGase up-regulation.</p>Formule :C14H25N3O8SDegré de pureté :97.49%Couleur et forme :SolidMasse moléculaire :395.43Antifungal agent 123
<p>Antifungalagent 123 (Compound 4b) demonstrates strong affinity for the oxidoreductase of Staphylococcus aureus or membrane proteins of Candida albicans, exhibiting both antibacterial and antifungal properties. Additionally, it is capable of scavenging free radicals, showcasing antioxidant effects. Antifungalagent 123 also inhibits the TLR signaling pathway and possesses anti-inflammatory activity.</p>Formule :C21H20N4O3Couleur et forme :SolidMasse moléculaire :376.409Vensobafusp alfa
CAS :<p>Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.</p>Couleur et forme :Liquid(R)-Zadavotide guraxetan
CAS :<p>Zadavotide guraxetan (PSMAI&T; PNT-2002) is an inhibitor of prostate-specific membrane antigen (PSMA) with potential antitumor activity, and it is useful for research targeting prostate cancer.</p>Formule :C63H92IN11O23Couleur et forme :SolidMasse moléculaire :1498.37RGB097
<p>RGB097 is an efficacious inhibitor of D-dopachrome tautomerase (D-DT), with an IC50 value of 0.5 µM. It holds potential for applications in cancer research.</p>Formule :C26H22F3N5O3Masse moléculaire :509.16747Corza6
<p>Corza6 is a potent and selective peptide inhibitor of the human voltage-gated proton channel (hHv1). It binds to the external voltage sensor domain (VSD) loop in hHv1 at a resting membrane potential (RMP) of natural hyperpolarization in mammalian cells with a Kd of approximately 1 nM. Corza6 facilitates sperm capacitation and permits sustained production of reactive oxygen species (ROS) in leukocytes (WBC).</p>Formule :C203H293N55O61S7Couleur et forme :SolidMasse moléculaire :4704.29Clivatuzumab
CAS :<p>Clivatuzumab is a humanized anti-myxinomab, which can target the MUC1 epitope highly expressed on the surface of most pancreatic cancer cells, and has a good</p>Degré de pureté :SDS-PAGE:95% SEC-HPLC:99.99%Couleur et forme :LiquidMasse moléculaire :145.42 kDaEritoran
CAS :<p>Eritoran: TLR4 antagonist; shields mice from lethal influenza, EBOV, MARV; reduces granulocytosis, eases cytokine storm.</p>Formule :C66H126N2O19P2Couleur et forme :SolidMasse moléculaire :1313.66Pegaldesleukin
CAS :<p>Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.</p>Couleur et forme :LiquidCD19 CAR mRNA
<p>CD19 CAR mRNA expresses a protein for use in CAR-CD19 T cell therapy, targeting B cell antigen for cancer treatment.</p>Couleur et forme :SolidBiotin-labeled ODN 2395 sodium
<p>Biotin-labeled ODN 2395 (sodium), a Class C oligodeoxynucleotide and TLR9 agonist, serves to assess cellular uptake and localization of CpG ODN through a biotin</p>Couleur et forme :Odour SolidAra-F-NAD+
CAS :<p>Ara-F-NAD+, an arabino analogue of NAD + , is a potent, slow-binding CD38 NADase inhibitor, with a K i of 169 nM.</p>Formule :C21H26FN7O13P2Couleur et forme :SolidMasse moléculaire :665.421NLRP3-IN-35
<p>NLRP3-IN-35 (compound 11) is an NLRP3 inhibitor with an IC50 of less than 1 μM.</p>Formule :C26H25FN4O2Masse moléculaire :444.19615cGAMP diammonium
<p>cGAMP is a second messenger that triggers interferon production via STING activation upon detecting cytosolic DNA.</p>Formule :C20H30N12O13P2Couleur et forme :SolidMasse moléculaire :708.47Reltecimod
CAS :Reltecimod, a CD28 antigen inhibitor, is used potentially for the treatment of necrotizing soft tissue infection.Formule :C46H72N10O15SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1037.19Dihydromyristicin
CAS :<p>Dihydromyristicin, a plant flavonoid, curbs inflammation by inhibiting ROS and PI3K/Akt/NF-κB pathways.</p>Formule :C11H14O3Couleur et forme :SolidMasse moléculaire :194.23Ibritumomab
<p>Ibritumomab is a murine-derived anti-CD20 monoclonal antibody that kills tumor cells by forming free radicals in target cells and surrounding tissues.</p>Degré de pureté :96% (SDS-PAGE); 95.9% (SEC-HPLC) - 96% (SDS-PAGE); 95.9% (SEC-HPLC)Couleur et forme :Odour LiquidModakafusp alfa
CAS :<p>Modakafusp alfa (TAK-573): Humanized anti-CD38 monoclonal antibody with IFNα2b for multiple myeloma research.</p>Couleur et forme :LiquidPROTAC IRAK4 degrader-2
CAS :<p>PROTAC IRAK4 degrader-2 reduces IRAK4 in PBMCs with a DC50 of 36 nM and inhibits cytokines.</p>Formule :C57H68FN11O8SCouleur et forme :SolidMasse moléculaire :1086.28Keap1-Nrf2-IN-9
CAS :<p>Keap1-Nrf2-IN-9 inhibits Keap1-Nrf2 PPI with 0.575 µM IC50, boosts Nrf2 genes, non-toxic in ARPE19 cells.</p>Formule :C31H30N2O11S2Couleur et forme :SolidMasse moléculaire :670.71KRN7000 analog 1
<p>KRN7000 analog 1 stimulates a strong Th1-biased immune response by inducing interferon-γ (IFN-γ) and reducing interleukin-4 (IL-4). This compound shows potential as an antitumor agent and vaccine adjuvant.</p>Formule :C47H76FNO9SMasse moléculaire :849.52248Cafestol palmitate
CAS :<p>Cafestol palmitate is an active compound found in green coffee beans. It can enhance the activity of glutathione S-transferase (GST) in mice and also exhibits weak COX-2 inhibitory activity.</p>Formule :C36H58O4Couleur et forme :SolidMasse moléculaire :554.843CTT2274
<p>CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.</p>Formule :C119H159N17O33P2Couleur et forme :SolidMasse moléculaire :2417.58AM-103 Free Acid
CAS :<p>AM-103 Free Acid is a bio-active chemical.</p>Formule :C36H39N3O4SCouleur et forme :SolidMasse moléculaire :609.78PMX 205
CAS :<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Formule :C45H62N10O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.04Anti-inflammatory agent 88
Anti-inflammatory agent 88 (compound 6) is a carbazole derivative found in marine Streptomyces with anti-inflammatory properties. It exerts its effects by inhibiting pro-inflammatory factors and enhancing the expression of anti-inflammatory factors within the Myd88/Nf-κB pathway. This compound holds potential for the development of anti-inflammatory drugs.Formule :C13H10BrNO2Masse moléculaire :290.98949BCL6 PROTAC 1
CAS :<p>BCL6 PROTAC 1: Selective BCL6 degrader, IC50 8.8 µM, used in DLBCL research.</p>Formule :C45H52ClN9O12Couleur et forme :SolidMasse moléculaire :946.43-(3-Methoxyphenyl)acrylic acid
CAS :<p>3-(3-Methoxyphenyl)acrylic acid can inhibit free radical generation, has antioxidant potential, and can be used in biochemical experiments and drug synthesis.</p>Formule :C10H10O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :178.19TMV-IN-7
<p>TMV-IN-7 (compound G2) is a potent inhibitor of Tobacco Mosaic Virus (TMV). It exhibits strong hydrophobic interactions that prevent the virus from self-assembling.</p>Formule :C17H15ClN6OSMasse moléculaire :386.07166Antibacterial agent 273
<p>Antibacterialagent 273 (Compound 15e) is an antimicrobial agent targeting bacterial cell membranes, effectively disrupting them with a MIC value of 4 μg/mL against Staphylococcus aureus. It causes the leakage of intracellular nucleic acids and proteins, inhibits bacterial metabolic activity, and induces the accumulation of reactive oxygen species (ROS) within bacteria. Antibacterialagent 273 is applicable in research on infections caused by Staphylococcus aureus.</p>Couleur et forme :Odour SolidFAPI-46
CAS :<p>FAPI-46 is a radiotracer for fibroblast activation protein (FAP),conjugated with 68Ga or 177Lu tracer for FAP tumours in positron emission tomography (PET).</p>Formule :C41H57F2N11O9Couleur et forme :SolidMasse moléculaire :885.96RDR03785
CAS :<p>The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.</p>Formule :C19H18F3NO4Degré de pureté :98.92%Couleur et forme :SolidMasse moléculaire :381.35Complement C1s-IN-1
CAS :<p>Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexes</p>Formule :C22H20F2N6ODegré de pureté :97.77%Couleur et forme :SoildMasse moléculaire :422.43ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Couleur et forme :SolidMasse moléculaire :120702.76KTX-497
CAS :<p>KTX-497, an IRAK4 degrader, demonstrates a potent DC50 value of 3 nM. It is utilized in oncology research[1].</p>Formule :C45H49F3N8O6Couleur et forme :SolidMasse moléculaire :854.92Topramezone
CAS :<p>Topramezone is a 4-HPPD inhibitor herbicide for post-emergence weed control in corn.</p>Formule :C16H17N3O5SCouleur et forme :SolidMasse moléculaire :363.3912-Oxo phytodienoic acid
CAS :<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formule :C18H28O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.41Amaroswerin
CAS :<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formule :C29H30O14Couleur et forme :SolidMasse moléculaire :602.54Inflexuside B
CAS :<p>Inflexuside B, an abietane diterpenoid derived from the aerial parts of Isodon inflexus, effectively inhibits lipopolysaccharide (LPS)-activated NO Synthase in</p>Formule :C35H48O11Couleur et forme :SolidMasse moléculaire :644.75Ac-macropa
Ac-macropa is a conjugate of Actinium-225 that targets PSMA, and it is useful for researching prostate cancer.Formule :C39H52AcN6O9SMasse moléculaire :1007.37943-Methoxycatechol
CAS :<p>3-Methoxycatechol: lignin-based, esophageal carcinogen. 1,2-Dihydroxy-3-methoxybenzene: potent anti-EMCV.</p>Formule :C7H8O3Degré de pureté :99.31%Couleur et forme :SolidMasse moléculaire :140.14Chitohexaose hexahydrochloride
CAS :<p>Chitohexaose hexahydrochloride, a TLR4-inhibiting chitosan derivative, blocks LPS-induced inflammation.</p>Formule :C36H74Cl6N6O25Couleur et forme :SolidMasse moléculaire :1203.71Maritimetin
CAS :<p>Maritimein, an aurone from Coreopsis tinctoria, has potent antioxidant activity (IC50: 4.12 μM) and is used in cardiovascular research.</p>Formule :C15H10O6Couleur et forme :SolidMasse moléculaire :286.24NH2-UAMC1110 TFA
CAS :<p>NH2-UAMC1110 TFA, a derivative of the fibroblast activation protein (FAP) inhibitor UAMC1110, serves as a precursor in the formation of FAPI-QS, a chelating</p>Formule :C23H24F5N5O5Degré de pureté :99.02%Couleur et forme :SolidMasse moléculaire :545.46PROTAC IRAK4 degrader-6
CAS :<p>PROTAC IRAK4 degrader-6, potent, targets Cereblon to degrade IRAK4, detailed in US20190192668A1.</p>Formule :C42H41F3N12O8Couleur et forme :SolidMasse moléculaire :898.861Pratensein
CAS :<p>Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.</p>Formule :C16H12O6Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :300.26TMV-IN-6
<p>TMV-IN-6 (Compound 4g) serves as a novel antiviral and fungicidal agent that impedes tobacco mosaic virus (TMV) assembly, functioning by attachment to TMV coat</p>Formule :C29H27N3OSCouleur et forme :SolidMasse moléculaire :465.61PROTAC IRAK4 degrader-1
CAS :<p>PROTAC IRAK4 degrader-1 is a Cereblon based PROTAC, PROTAC IRAK4 ligand-1, the E3 ligase ligand Pomalidomide and the PROTAC linker AM-Imidazole-PA-Boc.</p>Formule :C44H39F3N12O7Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :904.85
