Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(148 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(112 produits)
- IκB/IKK(60 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(444 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3044 produits trouvés pour "Immunologie et Inflammation"
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17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS :<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495LC-MI-3
<p>LC-MI-3 is an orally active and potent PROTAC degrader of interleukin-1 receptor-associated kinase 4 (IRAK4), with a DC50 value of 47.3 nM. It effectively inhibits the activation of downstream NF-κB signaling. LC-MI-3 is applicable for research in both acute and chronic inflammatory skin conditions.</p>Formule :C39H36N8O8Masse moléculaire :744.26561UNC9036
<p>UNC9036 is a PROTAC degrader of STING, with a DC50 value of 227 nM. The degradation of STING mediated by UNC9036 is dependent on the proteasomal VHL pathway.</p>Formule :C73H95N17O11SMasse moléculaire :1417.71177SARS-CoV-2-IN-39
CAS :<p>SARS-CoV-2-IN-39 is a SARS-CoV-2 inhibitor with an EC50 of 1 μM.</p>Formule :C14H8ClF4NO3Degré de pureté :99.86%Couleur et forme :SoildMasse moléculaire :349.66H2-D b restricted epitopes VSV Nucleoprotein (52-59)
CAS :<p>H2-D b restricted epitopesVSVNucleoprotein (52-59) is a nonapeptide derived from the nucleoprotein of Vesicular Stomatitis Virus (VSV). It binds to MHC class I molecules to present itself to CD8+ T cells, thereby activating cytotoxic T lymphocytes (CTLs) that recognize and destroy cells expressing the corresponding antigen. This epitope is instrumental in the development of CTL vaccines against the Ebola virus.</p>Formule :C44H66N12O12Masse moléculaire :955.07mPGES-1/5-LOX-IN-1
<p>mPGES-1/5-LOX-IN-1 (compound 3j) is a potent, orally active dual inhibitor of mPGES-1 and 5-LOX, with IC50 values of 0.92 and 1.89 µM, respectively. Additionally, mPGES-1/5-LOX-IN-1 exhibits anti-inflammatory properties.</p>Formule :C20H22N4O6SMasse moléculaire :446.12601Taplitumomab paptox
CAS :<p>Taplitumomab paptox is an anti-CD19 monoclonal antibody utilized in cancer research.</p>Couleur et forme :LiquidCalcitriol Impurities D
CAS :<p>Calcitriol Impurities D: Vitamin hormone, promotes cell differentiation, has bone activity, inhibits HIV, and aids in treating AIDS/viral infections.</p>Formule :C28H46O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :430.66cGAS-IN-3
<p>cGAS-IN-3 (compound 30d-S) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) that exhibits excellent plasma exposure and low clearance rate. It demonstrates anti-inflammatory properties, significantly reducing pulmonary inflammation in rats.</p>Formule :C21H20Cl2F2N4O2Masse moléculaire :468.09314CP-447697
CAS :<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Formule :C29H26ClF2N3O2SDegré de pureté :99.90%Couleur et forme :SoildMasse moléculaire :554.05(-)-10,11-Dihydroxyfarnesol
CAS :<p>(-)-10,11-Dihydroxyfarnesol, from Cryptomarasmius aucubae, inhibits NO production.</p>Formule :C15H28O3Couleur et forme :SolidMasse moléculaire :256.38NOD1 antagonist-1
<p>NOD1antagonist-1 (compound 37) acts as an antagonist to NOD1 and exhibits a slight selectivity between NOD1 and NOD2, with IC50 values of 9.18 μM and 20.8 μM, respectively.</p>Formule :C24H32N4O2SMasse moléculaire :440.2246Antibiofilm agent-8
<p>Antibiofilm agent-8 (compound Ru2) boosts antibacterial activity under visible light (400-700 nm, 10 J cm-2). It induces oxidative stress by promoting NADH oxidation and reactive oxygen species (ROS) generation, which disrupts the bacterial cell wall.</p>Formule :C35H23ClF6N7PRuMasse moléculaire :823.03887Glutaminase C-IN-2
<p>Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.</p>Formule :C24H23N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.55Mifamurtide TFA
<p>Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.</p>Formule :C61H110F3N6O21PCouleur et forme :SolidMasse moléculaire :1351.52Ezeprogind
CAS :<p>Ezeprogind, TLR9 inhibitor for Alzheimer's. Affordable Excellence: Reliable Quality You Can Trust</p>Formule :C25H44N6Degré de pureté :99.28%Couleur et forme :SolidMasse moléculaire :428.66MUC1, mucin core
CAS :<p>MUC1: Type I transmembrane glycoprotein, overexpressed and abnormally glycosylated in cancer, binds ICAM-1 domain 1.</p>Formule :C61H101N19O24Couleur et forme :SolidMasse moléculaire :1484.588β-Amyrin acetate
CAS :<p>Beta-Amyrin acetate: HMGCR & sEH inhibitor (IC50 3.4 μM), anti-inflammatory, antifungal, antioxidant, anti-hyperlipidemic.</p>Formule :C32H52O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :468.75PROTAC IRAK4 degrader-5
CAS :<p>PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.</p>Formule :C41H40F3N11O9Couleur et forme :SolidMasse moléculaire :887.8346Lac[6]Met
CAS :<p>6Lac[6]Met is a galectin-4 inhibitor with an IC50 value of 5 μM [1].</p>Formule :C126H180N12O66S6Couleur et forme :SolidMasse moléculaire :3111.21VEN-02XX
<p>VEN-02XX is an orally active NLRP3 inhibitor capable of penetrating the brain. It effectively suppresses the release of IL-1β and IL-18, with IC50 values of 0.3 and 0.28 μM, respectively. In the 5XFAD/Rubicon KO mouse model, VEN-02XX aids in restoring memory and cognition, inhibits microgliosis, and alleviates neuroinflammation and tau protein pathology. This compound is valuable for Alzheimer's disease (AD) research.</p>Formule :C18H16ClF3N4OCouleur et forme :SolidMasse moléculaire :396.79CAY10512
CAS :<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formule :C15H13FOCouleur et forme :SolidMasse moléculaire :228.266Suc-Tyr-Val-Ala-Asp-pNA
CAS :<p>Suc-YVAD-pNA, a chromogenic caspase-1 substrate.</p>Formule :C31H38N6O12Couleur et forme :SolidMasse moléculaire :686.675HSV-60mer sodium
<p>HSV-60mer sodium is a 60 bp double-stranded oligonucleotide that includes viral DNA motifs from the herpes simplex virus 1 (HSV-1) genome. Transfection of HSV-60mer effectively induces IFN-β in a manner dependent on STING, TBK1, and IFN regulatory factor 3 (IRF3).</p>Lonazolac Calcium
CAS :<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Formule :C34H24CaCl2N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :663.56Mitoquinone mesylate
CAS :<p>Mitoquinone mesylate (MitoQ10 mesylate) is a potent TRAP1 inhibitor (IC50=0.2 μM). Mitoquinone mesylate is an antioxidant. High-Quality, Low-Cost!</p>Formule :C38H47O7PSDegré de pureté :98.36%Couleur et forme :SolidMasse moléculaire :678.81Benz-AP
CAS :<p>Benz-AP: potent photosensitizer, creates singlet oxygen, more toxic in low hCES2 cancer cells, generates ROS via TPE to kill tumors.</p>Formule :C20H13NO2Couleur et forme :SolidMasse moléculaire :299.32TMX-201
CAS :<p>TMX-201: TLR7 ligand-phospholipid with potent immune-boosting effect; for breast cancer & melanoma study.</p>Formule :C57H93N6O12PCouleur et forme :SolidMasse moléculaire :1085.36M-TriDAP TFA
<p>M-TriDAP (N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid) TFA is a bioactive peptide that functions as an agonist for NOD1/2.</p>Formule :C26H43N5O15·xC2HF3O2HPK1-IN-57
<p>HPK1-IN-57 (Compound 10c) is an inhibitor of hematopoietic progenitor kinase 1 (HPK1) with an IC50 of 0.09 nM. It suppresses the activity of HPK1 kinase, inhibits the phosphorylation of downstream adaptor protein SLP76 (IC50 of 33.74 nM), and effectively induces the secretion of the T cell activation marker IL-2 (EC50 of 84.24 nM). HPK1-IN-57 holds promise for research in tumor immunotherapy.</p>Formule :C30H36F2N8O3Couleur et forme :SolidMasse moléculaire :594.655BCOR(498-514), biotinylated
<p>BCOR(498-514), biotinylated, is the smallest BCL6 binding domain with a KD of 1.32 µM. It can block BCL6-mediated transcriptional repression and induce cell death in lymphoma cells.</p>Formule :C98H155N25O29SMasse moléculaire :2178.11433WAY-605471
CAS :<p>WAY-605471 is a AHR antagonist with IC50 of 0.5 - 1 μM.</p>Formule :C14H15NO3S2Degré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :309.4STING modulator-5
CAS :<p>STING modulator-5: pIC50 9.5, antagonizes PBMC (pIC50 8.1), THP-1 cell antagonist, for immunology research.</p>Formule :C43H45F4N11O5Couleur et forme :SolidMasse moléculaire :871.88NOD1 antagonist-2
<p>NOD1antagonist-2 (compound 66) is an orally active and selective inhibitor that can suppress NOD1 in both humans and mice. It effectively blocks the NOD1-induced NF-κB and MAPK pathways.</p>Formule :C21H13Cl2F2N3O5S2Couleur et forme :SolidMasse moléculaire :560.378Ara-F-NAD+ sodium
<p>Ara-F-NAD+ sodium, an arabino analogue of NAD+, serves as a potent, reversible, and slow-binding inhibitor of the CD38 NADase [1] [2].</p>Formule :C21H25FN7NaO13P2Couleur et forme :SolidMasse moléculaire :687.4MyD88-IN-2
<p>MyD88-IN-2 (compound A5S) is a MyD88 inhibitor with a Kd value of 15 μM. It demonstrates protective effects in mouse models of acute lung injury induced by LPS and sepsis.</p>Formule :C22H26BrN3O2Couleur et forme :SolidMasse moléculaire :444.365GB2095
<p>GB2095 is an orally effective and selective inhibitor of galectin-3, exhibiting binding affinities (Kd) of 36 nM for human galectin-3 and 0.35 μM for mouse galectin-3. In mouse models, GB2095 demonstrates antitumor activity.</p>Formule :C20H17BrClF2N3O4SCouleur et forme :SolidMasse moléculaire :548.785Bifarcept
CAS :<p>Bifarcept, a recombinant antibody targeting the interferon receptor type I (IFN-RI), enhances the serum half-life of IFN-β by facilitating its binding.</p>Couleur et forme :LiquidChitoheptaose heptahydrochloride
CAS :<p>Chitoheptaose heptahydrochloride, a chitosan derivative, enhances wheat growth and photosynthesis, with health-protective traits.</p>Formule :C42H80ClN7O29Couleur et forme :SolidMasse moléculaire :1182.57Z-VRPR-FMK TFA
<p>Z-VRPR-FMK (TFA), a tetrapeptide, irreversibly inhibits MALT1, protecting against influenza A.</p>Formule :C33H50F4N10O8Couleur et forme :SolidMasse moléculaire :790.81Porphyra 334
CAS :<p>Porphyra 334 is a mycosporine-like amino acid.</p>Formule :C14H22N2O8Couleur et forme :SolidMasse moléculaire :346.336ROS-ERS inducer 1
<p>Type II ICD agent, ROS-ERS inducer 1, is a Pt(II)-NHC from 4,5-diarylimidazole, boosting ER stress, ROS, and DAMPs in HCC, outperforming Cisplatin.</p>Formule :C24H23F2I2N3PtCouleur et forme :SolidMasse moléculaire :840.35OATD-02 hydrochloride
<p>OATD-02 hydrochloride is the hydrochloride salt form of OATD-02. It is an orally effective, competitive, reversible, and non-covalent dual inhibitor of Arginase1 and Arginase2. OATD-02 hydrochloride serves as a sustained-release inhibitor that efficiently blocks the activity of intracellular arginases, with IC50 values of 20 nM (hARG1), 39 nM (hARG2), 39 nM (mARG1), and 28 nM (rARG1). It effectively eliminates tumor-induced immunosuppression caused by both types of arginases. This compound is utilized in research studies on melanoma.</p>Couleur et forme :Odour SolidHuman Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Couleur et forme :Odour SolidMitoquinol
CAS :<p>Mitoquinol is a mitochondria-targeted antioxidant used in the study of cardiovascular disease by modulating the mitochondrial antioxidant defense system.</p>Formule :C38H49O7PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :680.83RDR 02308
CAS :<p>RDR 02308 is a TLR4-MyD88 binding inhibitor that inhibits full-length β-lactamase [1] .</p>Formule :C19H15N3O3Couleur et forme :SolidMasse moléculaire :333.34POT-4 acetate
<p>POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.</p>Formule :C74H106N22O20S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1687.9InsB (9-23)
CAS :<p>InsB (9-23) (InsulinB chain (9-23)) is an insulin B chain peptide capable of binding to the class II major histocompatibility complex (MHC) allele I-Ag7. It holds potential for research into various autoimmune diseases, including type 1 diabetes.</p>Formule :C72H116N20O22SMasse moléculaire :1645.88UNC8900
<p>UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.</p>Formule :C75H99N17O15SMasse moléculaire :1509.72273ADU-S100 disodium salt
CAS :<p>ADU-S100 (MIW815) disodium salt is an activator of stimulator of interferon genes (STING).</p>Formule :C20H22N10Na2O10P2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :734.51
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