Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(148 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(112 produits)
- IκB/IKK(60 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(444 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3034 produits trouvés pour "Immunologie et Inflammation"
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Biotin-labeled ODN TTAGGG sodium
<p>Biotin-labeled ODN TTAGGG (sodium) is an inhibitory oligonucleotide (ODN) that functions as an antagonist to TLR9, AIM2, and cGAS.</p>Couleur et forme :Odour SolidSARS-CoV-2 Mpro-IN-41
<p>SARS-CoV-2 Mpro-IN-41 (Compound 7e) is an orally active inhibitor targeting COX-2 and SARS-CoV-2 Mpro, with respective IC50 values of 9.66 μM and 13.24 μM. It also demonstrates inhibitory activity against COX-1 (IC50: 46.11 μM). This compound significantly suppresses the expression of inflammation-related cytokines such as TNF-α, IL-6, and IL-1β, exhibiting anti-inflammatory properties. By selectively inhibiting COX-2 and SARS-CoV-2 Mpro, SARS-CoV-2 Mpro-IN-41 exerts both anti-inflammatory and antiviral effects, making it a potential candidate for research in inflammation and COVID-19 treatment.</p>Formule :C27H23ClN4O3SCouleur et forme :SolidMasse moléculaire :518.11794GHN105
<p>GHN105 is an orally active STING inhibitor that suppresses STING-dependent IFN-β secretion in THP-1 human monocytes with an IC50 of 4.4 μM. In mice, GHN105 reduces serum levels of IFN-β, IL-6, and CXCL10, and alleviates colitis in a DSS-induced acute colitis mouse model. Additionally, GHN105 demonstrates favorable pharmacokinetic properties in mice, with an oral bioavailability of 43% and a half-life of 1.1 hours.</p>Formule :C41H56N2O14Couleur et forme :SolidMasse moléculaire :800.89CD19 CAR circRNA
<p>CD19 CAR circRNA expresses a CD19 car protein for CAR-T immunotherapy targeting B-cell antigens.</p>Couleur et forme :SolidTSR-033
CAS :<p>TSR-033 is a human IgG4 antibody with high affinity for LAG-3 (lymphocyte activation gene-3), a co-receptor linked to diminished T cell activity, frequently co-</p>Couleur et forme :LiquidFentiazac
CAS :<p>Fentiazac (BR-700) is an oral NSAID for pain, inflammation, fever, studied for arthritis and tendonitis.</p>Formule :C17H12ClNO2SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :329.8Prifelone
CAS :<p>Prifelone (R 830) is a non-steroidal anti-inflammatory compound with antioxidant activity.</p>Formule :C19H24O2SDegré de pureté :99.8%Couleur et forme :SolidMasse moléculaire :316.46RH-EDA
<p>RH-EDA, a rhodamine-based turn-on fluorescent probe, detects hydroxyl radicals ([OH]) in living systems.</p>Formule :C28H25N3O4Couleur et forme :SolidMasse moléculaire :467.52MC4762
<p>MC4762 is an inhibitor of NOX2 and MAOB, with IC50 values of 0.155 μM and 0.182 μM, respectively. It exhibits anti-inflammatory properties by suppressing the production of ROS and downregulating the expression of pro-inflammatory cytokines such as iNOS, IL-1β, and IL-6.</p>Couleur et forme :Odour SolidSTING ligand-4
<p>STING ligand-4 (Compound 2) is a nitro-free covalent STING inhibitor with an IC50 of less than 0.2 μM. It can be utilized in the synthesis of PROTACSTINGdegrader-4.</p>Formule :C18H18Cl2N6OCouleur et forme :SolidMasse moléculaire :404.09191α-Glucosidase/NLRP3-IN-1
<p>α-Glucosidase/NLRP3-IN-1 (Compound 8) acts as a dual inhibitor targeting both α-glucosidase and NLRP3. It features an IC50 value of 6.6 μM for α-glucosidase and inhibits NLRP3 across multiple cell lines at a concentration of 100 μM. This compound demonstrates neuroprotective and antidiabetic properties, making it suitable for related research.</p>Formule :C38H54O4Couleur et forme :SolidMasse moléculaire :574.83Zomiradomide
CAS :<p>Zomiradomide is a PROTAC degradation agent targeting IRAK4,oral, Ikaros (IKZF1) and Aiolos (IKZF3), NF-κB type I interferon, B-cell lymphoma.</p>Formule :C45H48F3N7O6SDegré de pureté :98.41%Couleur et forme :SolidMasse moléculaire :871.97Fianlimab
CAS :<p>Fianlimab (REGN3767) is a monoclonal antibody targeting LAG-3, exhibiting anti-tumor activity, and can be used in melanoma research.</p>Degré de pureté :>95%Couleur et forme :LiquidCartap hydrochloride
CAS :<p>Cartap hydrochloride is an insecticidal derivative. It is used to control chewing and sucking insects on many crops.</p>Formule :C18H33Cl2CuN3O3Couleur et forme :Colorless Crystalline Slightly Hygroscopic Solid CoaMasse moléculaire :473.93N(G)-Nitroarginine-4-nitroanilide
CAS :<p>N(G)-Nitroarginine-4-nitroanilide is an anti-nociceptive in mice.</p>Formule :C12H17N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :339.31Amfenac sodium
CAS :<p>Amfenac is a nonsteroidal anti-inflammatory drug. Amfenac also has acetic acid moiety.</p>Formule :C15H12NNaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :277.26Aβ-IN-6
<p>Aβ-IN-6 is an orally active compound exhibiting anti-inflammatory, antioxidant, and anti-oligomeric activities, with significant implications for Alzheimer's</p>Formule :C28H31N3O4Couleur et forme :SolidMasse moléculaire :473.56Perfluorododecanoic acid
CAS :<p>Perfluorododecanoic acid (PFDoA) is a PFAS pollutant causing ROS increase, mitochondrial damage, and neuronal cytotoxicity.</p>Formule :C12HF23O2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :614.1DA-E 5090
CAS :<p>DA-E 5090, an active metabolite of E 5090, inhibits IL-1 production in human monocytes.</p>Formule :C17H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.32PSMA-ALB-56
CAS :<p>PSMA-ALB-56: radioactive, PSMA-targeted ligand, antitumor, combines glutamic urea, DOTA, albumin, with iodophenyl or tolyl fragments.</p>Formule :C66H95N11O18Couleur et forme :SolidMasse moléculaire :1330.52RS 09 TFA
<p>RS 09 TFA is a TLR4 agonist and LPS peptide analogue, promotes NF-κB nuclear translocation, induces inflammatory cytokine secretion in RAW264.7 macrophages.</p>Formule :C33H50F3N9O11Degré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :805.8Varokibart
CAS :<p>Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1].</p>Couleur et forme :Liquid4-hydroperoxy 2-Nonenal
CAS :<p>4-HNE, a marker of oxidative stress, arises from oxidized ω-6 fats like linoleic acid and shows cytotoxic and genotoxic effects.</p>Formule :C9H16O3Couleur et forme :SolidMasse moléculaire :172.224BMS-986148
<p>BMS-986148 is a CHO-expressed humanized antibody-drug coupling targeting mesothelin-expressing cells for cytotoxic load delivery.</p>Degré de pureté :98.1% (SDS-PAGE); 99% (SEC-HPLC) - 98.1% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :Odour LiquidZuberitamab
CAS :<p>Zuberitamab (HS006) is a monoclonal antibody targeting CD20, utilized in cancer research, notably in diffuse large B-cell lymphoma [1].</p>Couleur et forme :LiquidLonazolac Calcium
CAS :<p>Lonazolac Calcium, a nonsteroidal anti-inflammatory drug (NSAID), is used to treat inflammation and pain.</p>Formule :C34H24CaCl2N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :663.56Schisanchinin D
CAS :<p>Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.</p>Formule :C23H30O6Couleur et forme :SolidMasse moléculaire :402.487PSMA-D5
CAS :<p>PSMA-D5 exhibits a binding affinity for PSMA with a Ki of 0.21 nM and becomes useful for PSMA tracing following radiolabeling. When marked with [68Ga], PSMA-D5 contains a DOTA chelator, facilitating the convenient labeling with therapeutic radionuclides such as 177Lu and 225Ac. Additionally, [68Ga]-labeled PSMA-D5 demonstrates exceptional pharmacokinetic properties and significant tumor uptake in 22Rv1 tumors. This compound can be employed in the synthesis and research of radiolabeled conjugates (RDC).</p>Formule :C57H80N12O24Couleur et forme :SolidMasse moléculaire :1317.31DZ-837
<p>DZ-837 is a PROTAC that targets the BCL6 protein. The composition of DZ-837 includes the BCL6 ligand-2, the E3 ubiquitin ligase ligand Thalidomide-4-OH, and a PROTAC Linker. The configuration notably features a conjugate of the E3 ubiquitin ligase ligand and the Linker, designated as 2-(2,6-Dioxopiperidin-3-yl)-4-((2-(2-hydroxyethoxy)ethyl)amino)isoindoline-1,3-dione.</p>Formule :C42H44FN9O7SCouleur et forme :SolidMasse moléculaire :837.924-Methylamino antipyrine hydrochloride
CAS :<p>4-Methylamino antipyrine hydrochloride is an active metabolite of Metamizole.</p>Formule :C12H16ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :253.73Factor B-IN-5
CAS :<p>Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.</p>Formule :C27H32N2O4Degré de pureté :98.19%Couleur et forme :SoildMasse moléculaire :448.55Axinelline A
CAS :<p>Axinelline A: COX inhibitor, IC50 of 2.22 μM (COX-2) & 8.89 μM (COX-1), anti-inflammatory.</p>Formule :C12H15NO6Couleur et forme :SolidMasse moléculaire :269.25N-Acetyldopamine dimer-2
CAS :<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Formule :C20H20N2O6Couleur et forme :SolidMasse moléculaire :384.38Biotin-labeled Agatolimod sodium
<p>Biotin-labeled Agatolimod (sodium), a class B CpG ODN (oligodeoxynucleotide) and TLR9 agonist, facilitates the assessment of cellular uptake and localization of</p>Couleur et forme :Odour SolidIFN-α Receptor Recognition Peptide 1
CAS :<p>IFN-α Receptor Recognition Peptide 1, associated with receptor interactions, is a peptide of IFN-α.</p>Formule :C35H59N13O12SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :885.99(Rac)-γ-Tocopherol
CAS :<p>(Rac)-γ-Tocopherol (DMPBQ) is an isoform of Vitamin E that undergoes conversion to γ-Tocopherol through the action of tocopherol cyclase.</p>Formule :C28H48O2Couleur et forme :SolidMasse moléculaire :416.68Guignardone L
CAS :<p>Guignardone L, a metabolite extracted from the endophytic fungus Guignardia mangiferae, possesses toll-like receptor 3 (TLR3) regulating activity [1].</p>Formule :C17H24O4Couleur et forme :SolidMasse moléculaire :292.37Amaroswerin
CAS :<p>Amaroswerin, a secoiridoid glucoside, has anti-inflammatory, antidiabetic, and other medicinal properties; it inhibits NO release at IC50 of 5.42 μg/mL.</p>Formule :C29H30O14Couleur et forme :SolidMasse moléculaire :602.54Pelgifatamab
CAS :<p>Pelgifatamab (BAY-2315497) is a prostate-specific membrane antigen (PSMA) antibody with potential anticancer activity that can be used to study prostate cancer.</p>Degré de pureté :97.9% (SDS-PAGE); 95.1% (SEC-HPLC) - 97.9% (SDS-PAGE); 95.1% (SEC-HPLC)Couleur et forme :LiquidPepinh-MYD
CAS :<p>Pepinh-MYD, a MyD88 inhibitor, incorporates both a domain sequence from MyD88 TIR and a protein transduction sequence to facilitate cell membrane penetration. This compound disrupts MyD88-mediated TLR signaling pathways, effectively inhibiting associated immune responses. Its design is particularly useful for investigating MyD88's function in viral infections.</p>Formule :C151H248N50O35S2Couleur et forme :SolidMasse moléculaire :3388.032-Iminobiotin
CAS :<p>2-Iminobiotin inhibits iNOS/nNOS; Ki: 21.8 μM (mouse iNOS), 37.5 μM (rat nNOS).</p>Formule :C10H17N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :243.33Antitumor agent-185
<p>Antitumor agent-185 (compound 3) exhibits significant antitumor effects, effectively inhibiting tumor growth and extending the survival period of mice in vivo.</p>Formule :C109H199N5O36P2Couleur et forme :SolidMasse moléculaire :2217.71AMG 108
<p>AMG 108 (MEDI 8968) is a fully human monoclonal antibody targeting IL-1R1, used in rheumatoid arthritis research.</p>Couleur et forme :LiquidMasse moléculaire :145.5kDaVadastuximab
<p>Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized anti-CD33 monoclonal antibody for the study of acute myeloid leukemia (AML).</p>Degré de pureté :98.5% (SDS-PAGE); 97.3% (SEC-HPLC) - 98.5% (SDS-PAGE); 97.3% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :145.5 kDaCHBO4
CAS :<p>CHBO4 is an hMAO-B inhibitor that is potent, reversible, competitive and selective.The IC50 value of CHBO4 against hMAO-B in the CHBO assay was 0.031 μM, and</p>Formule :C15H10BrFODegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :305.14SN50
CAS :<p>SN50 is a cell-permeable inhibitor of NF-κB nuclear translocation that protects against ventilator-induced acute lung injury in rats.</p>Formule :C129H230N36O29SDegré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :2781.5JH-FK-08
<p>JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.</p>Formule :C45H73N3O13Couleur et forme :SolidMasse moléculaire :864.073StemRegenin 1 Hydrochloride
CAS :<p>StemRegenin 1 Hydrochloride is an AhR antagonist (IC₅₀ = 127 nM) that inhibits RANKL-induced osteoclast generation and differentiation.</p>Formule :C24H24ClN5OSDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :466Somantadine
CAS :<p>Somantadine has antiviral activities and can be used for research on preventing and treating coronavirus-related diseases.</p>Formule :C14H25NDegré de pureté :99.9%Couleur et forme :SolidMasse moléculaire :207.35PSMα3
CAS :<p>PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies.</p>Formule :C128H192N28O30SCouleur et forme :SolidMasse moléculaire :2635.17
