Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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Fendosal
CAS :<p>Fendosal (HP-129), NSAID, 6.9-9.5x stronger than aspirin in chronic inflammation models.</p>Formule :C25H19NO3Degré de pureté :99.3%Couleur et forme :SolidMasse moléculaire :381.42TMV-IN-5
CAS :<p>TMV-IN-5 (compound 1a) serves as an antiviral/antifungal agent, specifically targeting and inhibiting the assembly of the tobacco mosaic virus (TMV) by binding</p>Formule :C22H23N3SCouleur et forme :SolidMasse moléculaire :361.5TLR7/8 agonist 9
CAS :<p>TLR7/8 agonist 9 (Compound 25a), exhibiting EC50 values of 40 nM and 23 nM for hTLR7 and hTLR8 respectively, demonstrates anti-tumor properties and enhances the</p>Formule :C20H26N6OCouleur et forme :SolidMasse moléculaire :366.46Veledimex racemate
CAS :<p>Veledimex racemate, the racemic form of veledimex, is an orally available, small-molecule ligand that activates the RheoSwitch Therapeutic System.</p>Formule :C27H38N2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :438.6Caspase-3 activator 1
<p>Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage.</p>Formule :C28H27N6O2RuS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :644.75(S)-BI 665915
CAS :<p>(S)-BI 665915 is an orally active inhibitor of oxadiazole-containing 5-lipoxygenase-activating protein (FLAP)(IC50 of 1.7 nM for FLAP binding)..</p>Formule :C24H26N8O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.52AD 0261
CAS :<p>AD 0261 is a radical scavenger. It has a strong inhibitory action on the generation of lipid peroxides and superoxide anions.</p>Formule :C27H31F2N3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.55STING agonist-10
CAS :<p>STING agonist-10 is a potent activator of the STING small molecule cyclic urea class (EC50: 2600 nM).STING activation is a highly promising immunotherapy.</p>Formule :C25H20ClF4N3O2Couleur et forme :SolidMasse moléculaire :505.89IKK-IN-1
CAS :<p>IKK-IN-1 is an inhibitor of IKK.</p>Formule :C22H26ClN3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.91ACHP Hydrochloride
CAS :<p>ACHP Hydrochloride (IKK-2 Inhibitor VIII) is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.</p>Formule :C21H25ClN4O2Degré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :400.9AHR antagonist 4
CAS :<p>AHR antagonist 4, potent with 82.2 nM IC50, inhibits AHR from patent WO2018146010A1 and shows anti-cancer properties.</p>Formule :C20H14F6N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :488.34BDW568
CAS :<p>BDW568, a prodrug of BDW-OH, serves as a stimulator of interferon genes (STING) agonist.</p>Formule :C12H12N4O2S2Couleur et forme :SolidMasse moléculaire :308.38JNJ-67856633
CAS :<p>JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric inhibitor of MALT1 protease .</p>Formule :C20H11F6N5O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :467.32(Rac)-BAY-985
CAS :<p>(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.</p>Formule :C27H30F3N9ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :553.58TMV-IN-3
CAS :<p>TMV-IN-3 is a chalcone derivative that inhibits TMV with a 120.3 μg/mL EC50, used in research on infection and cancer.</p>Formule :C28H26O4Couleur et forme :SolidMasse moléculaire :426.5α-Pyridoin
CAS :<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Formule :C12H12N2O2Couleur et forme :SolidMasse moléculaire :216.24Lipid peroxidation inhibitor 1
CAS :<p>Lipid peroxidation inhibitor 1 is an inhibitor of lipid peroxidation (IC50: 0.07 μM).</p>Formule :C24H32N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.52GW274150 phosphate
CAS :<p>GW274150 phosphate is a selective, orally active iNOS inhibitor with an IC50 of 0.2 μM. It mitigates experimental renal ischaemia-reperfusion injury.</p>Formule :C8H20N3O6PSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :317.3CCG-63802
CAS :<p>CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.</p>Formule :C26H18N4O2SDegré de pureté :90%Couleur et forme :SolidMasse moléculaire :450.51STING-IN-7
CAS :<p>STING-IN-7 (compound 21) serves as a potent inhibitor of the stimulator of interferon genes (STING) pathway, demonstrating an inhibitory concentration (IC50) of</p>Formule :C16H14ClN3ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :299.76MALT1-IN-6
CAS :<p>MALT1-IN-6 is a MALT1 protease inhibitor (Ki: 9 nM) that exhibits anticancer activity.</p>Formule :C18H12Cl2F3N9OCouleur et forme :SolidMasse moléculaire :498.25PROTAC IRAK4 degrader-8
CAS :<p>PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].</p>Formule :C43H50ClF2N11O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :874.38FEN1-IN-6
CAS :<p>FEN1-IN-6 (compound 9) is a potent Flap endonuclease-1 (FEN1, IC50 = 10 nM) inhibitor, crucial for DNA damage repair in mammalian cells, and additionally</p>Formule :C12H8N2O5S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.33GSK840
CAS :<p>GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase</p>Formule :C21H23N3O3Degré de pureté :99.7%Couleur et forme :SolidMasse moléculaire :365.43Tyrosinase-IN-22
CAS :<p>Tyrosinase-IN-22 (compound 4) serves as a potent inhibitor for tyrosinase substrates, namely L-tyrosine and L-dopa, exhibiting inhibitory concentrations (IC50s) of 60 nM and 30 nM, respectively. Additionally, it demonstrates significant antioxidant and anti-melanogenic properties, making it suitable for related research endeavors [1].</p>Formule :C7H5ClN2SCouleur et forme :SolidMasse moléculaire :184.64Anti-inflammatory agent 65
CAS :<p>Anti-inflammatory agent 65 (compound 29), a Hederagonic acid derivative, exhibits potent activity by inhibiting nitric oxide (NO) release, nuclear translocation</p>Formule :C49H71NO6S2Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :834.22Factor D inhibitor 6
CAS :<p>Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.</p>Formule :C23H22ClFN6O3Couleur et forme :SolidMasse moléculaire :484.92GW274150 dihydrochloride
CAS :<p>GW274150 (dihydrochloride) is a potent, selective inhibitor of human and rat inducible nitric oxide synthase (iNOS), exhibiting oral activity and NADPH-</p>Formule :C8H19Cl2N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.23TLR7 agonist 15
CAS :<p>TLR7 agonist 15 (compound 16b) is a potent activator of mouse macrophages and hPBMCs, demonstrating an EC50 of 18 nM.</p>Formule :C26H31N5OCouleur et forme :SolidMasse moléculaire :429.56CAY10464
CAS :<p>CAY10464 (AHR antagonist 7) is an AHR antagonist for the study of cancer and metabolic diseases.</p>Formule :C15H12Cl2ODegré de pureté :99.96%Couleur et forme :SolidMasse moléculaire :279.16IR-Crizotinib
CAS :<p>IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial</p>Formule :C53H57Cl2FIN7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1024.88Cergutuzumab amunaleukin
CAS :<p>Cergutuzumab amunaleukin (CEA-IL2v) is a CEA-targeted IL-2 variant immunocytokine for combination cancer immunotherapy with anti-tumor activity.</p>Degré de pureté :98% (SDS-PAGE); 99.7% (SEC-HPLC) - 98% (SDS-PAGE); 99.7% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :162.05 kDaIL-17A antagonist 3
CAS :<p>IL-17A antagonist 3 is an IL-17A antagonist.</p>Formule :C33H33ClN6O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :613.11RIPK1-IN-16
CAS :<p>RIPK1-IN-16 is an orally active, potent RIPK1 inhibitor that mitigates excessive inflammation via inhibition of RIPK1-mediated necroptosis in vivo.</p>Formule :C20H19N5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :393.46STING agonist-11
CAS :<p>STING agonist-11 is a potent activator of the small molecule cyclic urea class of STING (EC50: 18 nM).STING activation is a highly promising immunotherapy.</p>Formule :C25H20ClF4N3O2Couleur et forme :SolidMasse moléculaire :505.89Oxidized ATP trisodium salt
CAS :<p>Oxidized ATP trisodium salt (oATP) is a broad-spectrum inhibitor of P2 receptors, irreversibly antagonizing P2X7R activation and inhibiting c-reactive protein (</p>Formule :C10H11N5Na3O13P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.11PDE4-IN-8
CAS :<p>PDE4-IN-8 is a potent PDE4 inhibitor with IC50 0.93 nM for PDE4B2 and minor impact on IL13, IL4, IFNy (IC50: 4.04, 36.33, 2394 nM).</p>Formule :C18H22BNO4Couleur et forme :SolidMasse moléculaire :327.18MKA031
CAS :<p>MKA031 (compound 6y) is a non-competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.7 μM.</p>Formule :C21H17N5O2SCouleur et forme :SolidMasse moléculaire :403.46IRAK4-IN-6
CAS :<p>IRAK4-IN-6 is an oral IRAK4 inhibitor with a 4 nM IC50, targeting MyD88 L265P mutant DLBCL.</p>Formule :C25H32N10O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :504.59TLR9-IN-1
CAS :<p>TLR9-IN-1: selective, potent human TLR9 inhibitor (IC50: 7 nM), useful for researching immune-related diseases.</p>Formule :C23H31N7OCouleur et forme :SolidMasse moléculaire :421.54Leteprinim
CAS :<p>Leteprinim (AIT 082 acid) is an hypoxanthine derivative that stimulates in vitro neurite outgrowth and the production of adenosine and neurotrophins from</p>Formule :C15H13N5O4Degré de pureté :99.08%Couleur et forme :SolidMasse moléculaire :327.29FEN1-IN-7
CAS :<p>FEN1-IN-7 (compound 16), a selective Flap endonuclease-1 (FEN1) inhibitor with an IC50 of 18 nM, plays a role in DNA damage repair in mammalian cells.</p>Formule :C16H14N2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.36Ginsenoside Rk1
CAS :<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Formule :C42H70O12Degré de pureté :98.46% - 99.13%Couleur et forme :SolidMasse moléculaire :767WEHI-345
CAS :<p>WEHI-345 is a potent and selective RIPK2 inhibitor which shows NOD signalling events yet prevents inflammatory cytokine production.</p>Formule :C22H23N7ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :401.46GGTI 2147
CAS :<p>GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.</p>Formule :C28H30N4O3Degré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :470.56BRP-201
CAS :<p>BRP-201: selective mPGES-1 inhibitor (IC50: 0.42 μM), potential next-gen anti-inflammatory drug.</p>Formule :C28H27ClN4OSCouleur et forme :SolidMasse moléculaire :503.06Vipoglanstat
CAS :<p>Vipoglanstat: inhibits prostaglandin E synthase, anti-inflammatory, reduces leukocyte infiltration and lung injury from endotoxin/sepsis.</p>Formule :C30H34Cl2F5N5O3Couleur et forme :SolidMasse moléculaire :678.52FEN1-IN-5
CAS :<p>FEN1-IN-5 (compound 12A) is a potent Flap endonuclease-1 (FEN1) inhibitor with an IC50 value of 12 nM, playing a role in DNA repair mechanisms [1].</p>Formule :C21H17N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.44EG01377
CAS :<p>EG01377 is a NRP1 antagonist with antiangiogenic, antimigratory, and antitumor activity, Kd 1.32 μM, IC50s 609 nM for NRP1-a1/b1, inactive on NRP2.</p>Formule :C26H30N6O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :586.68TLR7 agonist 16
CAS :<p>TLR7 agonist 16 (compound 16d) is a potent activator of TLR7 with an EC50 value of 18 nM.</p>Formule :C25H29N5O2Couleur et forme :SolidMasse moléculaire :431.53
