Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(136 produits)
- CXCR(147 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(113 produits)
- IκB/IKK(61 produits)
- LTR(3 produits)
- MALT(23 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(445 produits)
- NOD(17 produits)
- NOS(63 produits)
- Nrf2(78 produits)
- PGE Synthase(31 produits)
- ROS(69 produits)
- TGF-beta/Smad(58 produits)
- TLR(66 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3035 produits trouvés pour "Immunologie et Inflammation"
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STING modulator-3
CAS :<p>STING modulator-3, a 43.1 nM R232 STING inhibitor, doesn't affect IRF-3 or TNF-β in THP-1 cells.</p>Formule :C18H17N9OCouleur et forme :SolidMasse moléculaire :375.39cGAS-IN-1
CAS :<p>cGAS-IN-1 (compound C20), a flavonoid that acts as a Cyclic GMP-AMP Synthase (cGAS) inhibitor, demonstrates IC50 values of 2.28 μM for human cGAS and 1.44 μM</p>Formule :C18H19NO8Couleur et forme :SolidMasse moléculaire :377.35Nrf2-IN-3
CAS :<p>Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.</p>Formule :C22H26N4O4SDegré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :442.53ABR-238901
CAS :<p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>Formule :C11H9BrClN3O4SDegré de pureté :98.63% - 98.71%Couleur et forme :SolidMasse moléculaire :394.63LTβR-IN-1
CAS :<p>LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.</p>Formule :C18H16N4O2Degré de pureté :98.93%Couleur et forme :SolidMasse moléculaire :320.35Iptacopan
CAS :<p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>Formule :C25H30N2O4Degré de pureté :99.07% - >99.99%Couleur et forme :SolidMasse moléculaire :422.52Xanthine oxidase-IN-10
CAS :<p>Xanthine oxidase-IN-10 (XO8 analog) is a xanthine oxidase (XO) inhibitor for the study of gout.</p>Formule :C10H8N2OSDegré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :204.25AVP-13358
CAS :<p>AVP-13358: a CD23/IgE inhibitor for treating immune, infection, and ENT disorders.</p>Formule :C30H29N5O2Degré de pureté :98.42%Couleur et forme :SolidMasse moléculaire :491.58ERDRP-0519
CAS :<p>ERDRP-0519 is an oral measles polymerase inhibitor, preventing disease in monkeys, with potent nanomolar efficacy against morbilliviruses.</p>Formule :C23H30F3N5O4SDegré de pureté :98.64% - 98.71%Couleur et forme :SolidMasse moléculaire :529.58CU-CPD107
CAS :<p>CU-CPD107 selectively activates TLR8 and ssRNA, inhibits TLR8 with R848 (IC50=13.7 μM), and coactivates with ssRNA.</p>Formule :C16H21IN2O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.25Sembragiline
CAS :<p>Sembragiline (EVT-302) is a selective MAO-B inhibitor for the study of Alzheimer's disease (AD).</p>Formule :C19H19FN2O3Degré de pureté :99.49% - 99.49%Couleur et forme :SolidMasse moléculaire :342.36RIPK1-IN-4
CAS :<p>RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s</p>Formule :C23H23N5O2Degré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :401.46Netakimab
CAS :<p>Netakimab (BCD 085) is a monoclonal antibody targeting interleukin-17A and can be used to study spondyloarthritis.</p>Degré de pureté :95%Couleur et forme :LiquidMasse moléculaire :145.74 kDaGW274150
CAS :<p>GW274150: selective oral iNOS inhibitor (Kd=40 nM), low activity on eNOS/nNOS, protective in acute lung injury.</p>Formule :C8H17N3O2SDegré de pureté :96.43%Couleur et forme :SolidMasse moléculaire :219.3IL-17 modulator 4
CAS :<p>IL-17 modulator 4 is a prodrug of IL-17 modulator 1, which acts as a potent modulator of IL-17.Cost-effective and quality-assured.</p>Formule :C27H34N6O2Degré de pureté :99.59%Couleur et forme :SolidMasse moléculaire :474.6Piflufolastat
CAS :<p>Piflufolastat (DCFPYL) is a PET imaging agent for prostate cancer PSMA.</p>Formule :C18H23FN4O8Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :442.4Antiviral agent 34
CAS :<p>Antiviral Agent 34 is an antiviral compound that inhibits influenza virus and inhibits the proliferation of influenza virus by modulating RNA polymerase.</p>Formule :C29H33N3O2SDegré de pureté :99.51%Couleur et forme :SoildMasse moléculaire :487.66Usnoflast
CAS :<p>Usnoflast (ZYIL1) is an NLRP3 inhibitor, inhibiting NLRP3 inflammasome activation, used in neurological disease research.</p>Formule :C21H29N3O3SDegré de pureté :98.79%Couleur et forme :SolidMasse moléculaire :403.54Supercinnamaldehyde
CAS :<p>Supercinnamaldehyde is a potent activator of transient receptor potential ankyrin 1 (TRPA1), exhibiting an EC50 of 0.8 μM, and induces activation of TRPA1 ion</p>Formule :C12H11NO2Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :201.22GB1107
CAS :<p>GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.</p>Formule :C20H16Cl2F3N3O4SDegré de pureté :98.33% - 99.87%Couleur et forme :SolidMasse moléculaire :522.32Oditrasertib
CAS :<p>Oditrasertib, a RIPK1 inhibitor characterized by an IC50 value below 100 nM, is employed in inflammation research.</p>Formule :C14H15F2N3O2Degré de pureté :98.65% - 99.65%Couleur et forme :SolidMasse moléculaire :295.28ADS032
CAS :<p>ADS032 (BT-032) is an NLRP1 and NLRP3 inhibitor with anti-inflammatory activity for the study of respiratory inflammation or infection.</p>Formule :C22H29NO4SDegré de pureté :98.37%Couleur et forme :SolidMasse moléculaire :403.54(±)-CPSI-1306
CAS :<p>(±)-CPSI-1306 (2-(3-(2,4-Difluorophenyl)-4,5-dihydroisoxazol-5-yl)-1-morpholinoethan-1-one) is a macrophage migration inhibitory factor (MIF) antagonist and can</p>Formule :C15H16F2N2O3Degré de pureté :97.46%Couleur et forme :SolidMasse moléculaire :310.3COX-2/15-LOX-IN-5
CAS :<p>COX-2/15-LOX-IN-5 (Compound 4f) functions as a dual inhibitor of COX-2 and 15-LOX, demonstrating both anti-inflammatory and antioxidant properties [1]. This compound effectively reduces NF-κB activation in RAW 264.7 macrophages that is induced by lipopolysaccharide.</p>Formule :C25H21N3O3SCouleur et forme :SolidMasse moléculaire :443.52MG-T-19
CAS :<p>MG-T-19, a TIM-3 inhibitor, inhibit the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs.</p>Formule :C18H8Br2ClF3N4O2SDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :596.6CVN293
CAS :<p>CVN293 is a inhibitor of the potassium channel KCNK13,BBB,It inhibits the production of the pro-inflammatory cytokine IL-1β induced by NLRP3 in microglia</p>Formule :C14H10FN7ODegré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :311.27Heme Oxygenase-1-IN-2
<p>Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.</p>Formule :C19H18ClN3OCouleur et forme :SolidMasse moléculaire :339.82C-di-IMP
CAS :<p>Cyclic-di-IMP (C-di-IMP), a STING agonist, serves as a research tool in tumor studies.</p>Formule :C20H22N8O14P2Couleur et forme :SolidMasse moléculaire :660.38NLRP3-IN-80
CAS :<p>NLRP3-IN-80 (Compound 1) is an NLRP3 inhibitor useful for research into inflammatory aging.</p>Formule :C24H22F2N4O3Couleur et forme :SolidMasse moléculaire :452.45Galectin-3-IN-3
CAS :<p>Galectin-3-IN-3 (Compound 4) serves as a selective and orally active inhibitor targeting Gal-3. It exhibits IC50 values of 11 nM for mGal-3 and 84 nM for hGal-3 [1].</p>Formule :C25H22ClF2N7O4SCouleur et forme :SolidMasse moléculaire :590.00MMG-11 quarterhydrate
<p>MMG-11 quarterhydrate, a potent hTLR2 antagonist, inhibits TLR2/1 and TLR2/6 with IC50s of 1.7μM and 5.7μM; low toxicity.</p>Formule :C15H16O8Couleur et forme :SolidMasse moléculaire :310.78PB01
CAS :<p>PB01 is a DPP-4 inhibitor with an IC50 of 15.66 nM. It effectively suppresses high glucose-induced ROS generation and mitochondrial superoxide production while significantly reducing the cellular expression of DPP-4. Additionally, PB01 notably lowers blood glucose levels in diabetic mice. It demonstrates excellent safety, exhibiting almost no cytotoxicity at a concentration of 100 μM. PB01 holds promise for research in the diabetes field.</p>Formule :C18H21N5O3Couleur et forme :SolidMasse moléculaire :355.391ALR-6
CAS :<p>ALR-6, an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP, possesses anti-inflammatory properties. It significantly inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM without substantially affecting direct inhibition of 5-LOX [1].</p>Formule :C18H14O5Couleur et forme :SolidMasse moléculaire :310.3AhR agonist 7
CAS :<p>Compound 8, an AhR agonist 7, demonstrates potent activation of AhR with an EC50 of 13nM [1].</p>Formule :C16H15ClFNO2Couleur et forme :SolidMasse moléculaire :307.75(Rel)-Factor B-IN-5
CAS :<p>(Rel)-Factor B-IN-5 is a complement factor B inhibitor that can be used to study diseases associated with activation of the alternative complement pathway.</p>Formule :C27H32N2O4Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :448.55COX-2-IN-12
<p>COX-2-IN-12: Potent, selective COX-2 inhibitor, IC50=19.98μM, safe anti-inflammatory with low acute toxicity.</p>Formule :C17H19NO3Couleur et forme :SolidMasse moléculaire :285.34XO/COX/LOX-IN-1
<p>XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.</p>Formule :C24H20N4O2SCouleur et forme :SolidMasse moléculaire :428.51Ac5GalNTGc
CAS :<p>Ac5GalNTGc, an analog of hexosamine, inhibits mucin-type O-linked glycosylation biosynthesis [1].</p>Formule :C18H25NO11SCouleur et forme :SolidMasse moléculaire :463.46Factor B-IN-4
CAS :<p>Factor B-IN-4 is a potent inhibitor (IC50: 1 μM) of complement factor B. Factor B-IN-4 can be used to study inflammatory and immune-related diseases.</p>Formule :C27H32N2O4Couleur et forme :SolidMasse moléculaire :448.55Polvitolimod
CAS :<p>Polvitolimod is a TLR7 agonist used to treat infectious disease and cancer.</p>Formule :C13H14FN5O4Couleur et forme :SolidMasse moléculaire :323.28ODN 2088
CAS :<p>ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.</p>Couleur et forme :SolidTLR7/8 antagonist 2
<p>TLR7/8 antagonist 2: potent, orally active, IC50: 4.9 nM (TLR7), 0.6 nM (TLR8); potential for lupus therapy research.</p>Formule :C22H26FN5Couleur et forme :SolidMasse moléculaire :379.47YE6144
CAS :<p>YE6144, IRF5 phosphorylation blocker. Affordable Excellence: Reliable Quality You Can Trust</p>Formule :C21H27ClFN7OCouleur et forme :SolidMasse moléculaire :447.94Anti-inflammatory agent 10
<p>Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.</p>Formule :C17H13BrN4O3S2Couleur et forme :SolidMasse moléculaire :465.34COX-2-IN-13
<p>COX-2-IN-13 is a potent, selective COX-2 inhibitor with 0.98 μM IC50; shows strong anti-inflammatory properties and low acute toxicity.</p>Formule :C19H18N2O5SCouleur et forme :SolidMasse moléculaire :386.42Galectin-3-IN-4
CAS :<p>Galectin-3-IN-4 (compound 5), a carboxamide analog, effectively and selectively inhibits both human and mouse galectin-3. This compound demonstrates notable potency with IC50 values of 21 nM for hGal-3 and 167 nM for mGal-3. It is also orally bioavailable. For other galectins, Galectin-3-IN-4 shows IC50 values of 1580 nM for hGal-1 and 2750 nM for hGal-9, respectively [1].</p>Formule :C24H22ClF2N5O5SCouleur et forme :SolidMasse moléculaire :565.98IKZF1-degrader-1
CAS :<p>IKZF1-degrader-1 (Compound 9-B) serves as a potent degrader of the IKZF1 protein, exhibiting a DC50 of 0.134 nM. It is applicable in the degradation of tumors [1].</p>Formule :C35H29F2N5O3Couleur et forme :SolidMasse moléculaire :605.63Corannulene
CAS :<p>Corannulene is an agonist of the aromatic hydrocarbon receptor (AhR). It induces a lower cytotoxic response in liver cancer cells compared to Benzo[a]pyrene and shows potential for use in cancer research.</p>Formule :C20H10Couleur et forme :SolidMasse moléculaire :250.293AS2690168 hydrochloride
CAS :<p>AS2690168 hydrochloride is an orally active inhibitor of RANKL signaling that can suppress RANKL-induced osteoclastogenesis in RAW264 cells. AS2690168 is applicable in research related to pathological bone resorption.</p>Formule :C17H15Cl2F3N4OCouleur et forme :SolidMasse moléculaire :419.228MAY0132
CAS :<p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>Formule :C16H15ClF3NCouleur et forme :SolidMasse moléculaire :313.745
