Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(142 produits)
- CXCR(159 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(110 produits)
- IκB/IKK(59 produits)
- LTR(2 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(1 produits)
- NF-κB(443 produits)
- NOD(18 produits)
- NOS(61 produits)
- Nrf2(82 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(60 produits)
- TLR(76 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3365 produits trouvés pour "Immunologie et Inflammation"
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Glutathione monoethyl ester
CAS :Glutathione monoethyl ester, a derivative of glutathione, can protect motor neuron cells (NSC-34) from TDP-43 pathology caused by mutations, which includes reducing aggregate formation, nuclear clearance, reactive oxygen species (ROS) production, and cell death.Formule :C12H21N3O6SCouleur et forme :SolidMasse moléculaire :335.377Pelecopan
CAS :Pelecopan (BCX9930), an oral complement factor D inhibitor, prevents hemolysis in PNH (IC50=14.3 nM).Formule :C23H19FN2O4Couleur et forme :SolidMasse moléculaire :406.41IL-17 modulator 5
CAS :IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM .Formule :C28H23F6N9O2Couleur et forme :SolidMasse moléculaire :631.53AhR agonist 6
CAS :Compound 6, an AhR agonist, selectively activates the aryl hydrocarbon receptor (AhR) with an EC50 of 0.01 nM [1].Formule :C17H16F2O2Couleur et forme :SolidMasse moléculaire :290.30NOD1/2 antagonist-1
CAS :NOD1/2 antagonist-1 inhibits NOD1 (IC50 1.13 μM) and NOD2 (IC50 0.77 μM), enhances paclitaxel antitumor efficacy and is used to study innate immune signaling.Formule :C32H28ClF5N4O4Degré de pureté :99.69%Couleur et forme :SolidMasse moléculaire :663.03nNOS-IN-5
CAS :nNOS-IN-5 (Compound 9) is a potent inhibitor of human neuronal nitric oxide synthase (nNOS) with a Ki of 22 nM. It exhibits remarkable selectivity, being 900 times more selective for human nNOS over endothelial nitric oxide synthase (eNOS). nNOS-IN-5 is applicable in research related to neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.Formule :C23H22N4OCouleur et forme :SolidMasse moléculaire :370.447ND-2158
CAS :ND-2158 is a potent and selective inhibitor of IRAK4.Formule :C22H30N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :446.56PSMA ligand 1
CAS :PSMAligand 1 (Compound 1c) is a PSMA ligand with an IC50 of 26.74 nM. When labeled with [18F], PSMAligand 1 serves as a PSMAPET tracer for research related to the diagnosis of prostate cancer.Formule :C20H26FN3O9Couleur et forme :SolidMasse moléculaire :471.43(S,R,S)-AHPC-Boc derivative 1
CAS :(S,R,S)-AHPC-Boc derivative 1 (Compound 80-9; VH032-Boc derivative 1) is a selective proteasomal degrader targeting MALT1, which recruits the E3 ubiquitin ligase CRBN to form a ternary complex with MALT1. This interaction leads to the ubiquitination and subsequent proteasomal degradation of MALT1. By disrupting the CBM complex, (S,R,S)-AHPC-Boc derivative 1 inhibits the NF-κB signaling pathway and shows potential in inducing apoptosis in ABC-DLBCL cells. It holds promise for research into MALT1-dependent cancers, such as diffuse large B-cell lymphoma (DLBCL).Formule :C28H40N4O6SCouleur et forme :SolidMasse moléculaire :560.705AhR agonist 2
AhR agonist 2 is aryl hydrocarbon receptor (AhR) agonist,oral, inducing rapid nuclear enrichment of the AhR and facilitating skin barrier repair,psoriasis.Formule :C12H7Br2N3Couleur et forme :SolidMasse moléculaire :353.01Anti-inflammatory agent 10
Tilomisole-derived benzimidazole-thiazole, orally active, favors COX-2 inhibition over COX-1.Formule :C17H13BrN4O3S2Couleur et forme :SolidMasse moléculaire :465.34DPP4-In hydrochloride
CAS :DPP4-In (hydrochloride) is an inhibitor of dipeptidyl peptidase 4 (DPP4) that effectively reduces the expression of DPP4.Formule :C14H21ClN4O2Couleur et forme :SolidMasse moléculaire :312.8Nrf2-ARE/hMAO-B/QR2 modulator 1
CAS :Nrf2-ARE/hMAO-B/QR2 modulator 1 a resveratrol derivative activated the NRF2-ARE inhibit hMAO-B and QR2, promote hippocampal neurogenesis Alzheimer's disease .Formule :C14H12N2O3Degré de pureté :98.5%Couleur et forme :SolidMasse moléculaire :256.26DBMB
CAS :DBMB is a spleen tyrosine kinase (Syk) inhibitor that significantly suppresses Syk enzyme activity. It possesses anti-inflammatory properties by inhibiting NF-κB signaling, thereby reducing the production of inflammatory mediators such as nitric oxide (NO) and prostaglandin E2 (PGE2). DBMB can be utilized in research on inflammatory diseases.Formule :C24H22N4OCouleur et forme :SolidMasse moléculaire :382.458trans-3-(3-Pyridyl)acrylic acid
CAS :Trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid demonstrating antiviral activity against tobacco mosaic virus (TMV) [1].Formule :C8H7NO2Couleur et forme :SolidMasse moléculaire :149.15XO/COX/LOX-IN-1
<p>XO/COX/LOX-IN-1 targets XO/COX/LOX, used in research of inflammation, cancer, and metabolic disorders.</p>Formule :C24H20N4O2SCouleur et forme :SolidMasse moléculaire :428.51PVTX-405
CAS :PVTX-405 is a selective oral IKZF2 molecular glue degrader with a DC50 of 0.7 nM and a maximum degradation (Dmax) of 91%. It enhances degradation efficiency, significantly reduces off-target degradation, and minimizes hERG inhibition with an IC50 of 48 µM. PVTX-405 effectively inhibits MC38 tumor growth in Crbn391VC57BL/6 mouse xenograft models and shows superior synergistic anticancer effects when combined with immune checkpoint therapies (ICTs) such as anti-PD1 or anti-LAG3 antibodies.Formule :C30H31N5O4Couleur et forme :SolidMasse moléculaire :525.60IRAK1/4/pan-FLT3 Kinase-IN-2
CAS :IRAK1/4/pan-FLT3 Kinase-IN-2 (compound 27) is a potent dual inhibitor of IRAK1/4 and FLT3 with IC50 values of 10 nM, 0.7 nM, and < 0.5 nM, respectively. This compound enhances survival in mice models of acute myeloid leukemia.Formule :C20H22F3N5OCouleur et forme :SolidMasse moléculaire :405.42IRAK4-IN-31
CAS :IRAK4-IN-31 is a crystalline inhibitor of IRAK4. It is applicable in research related to myelodysplastic syndromes (MDS).Formule :C27H33N5O5Couleur et forme :SolidMasse moléculaire :507.58TMV-IN-8
CAS :TMV-IN-8 (compound 7d) is an anti-tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL. TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppresses TMV coat protein gene expression and biosynthesis process [1].Formule :C26H22N6O4Couleur et forme :SolidMasse moléculaire :482.49
