Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(143 produits)
- CXCR(158 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(110 produits)
- IκB/IKK(57 produits)
- LTR(3 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(2 produits)
- NF-κB(386 produits)
- NOD(25 produits)
- NOS(61 produits)
- Nrf2(81 produits)
- PGE Synthase(31 produits)
- ROS(71 produits)
- TGF-beta/Smad(60 produits)
- TLR(76 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3442 produits trouvés pour "Immunologie et Inflammation"
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JH-FK-08
JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.
Formule :C45H73N3O13Couleur et forme :SolidMasse moléculaire :864.073(±)11(12)-EET
CAS :(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.[1][2][3[]A higherFormule :C20H32O3Couleur et forme :SolidMasse moléculaire :320.47MT204
MT204 is a humanized IgG1 antibody inhibitor that targets IL-2 from human and rhesus monkey sources. It prevents soluble IL-2 from binding to the intermediate-affinity IL-2 receptor and blocks IL-2 bound to CD25 from interacting with the high-affinity IL-2 receptor. In rhesus monkey allogeneic skin transplant models, MT204 shows excellent tolerability and potent immunosuppressive activity. With linear pharmacokinetics, a reasonable serum half-life, and signs of good safety and efficacy, MT204 holds promise for use in immunotherapy.Couleur et forme :Odour LiquidVemircopan
CAS :Vemircopan is a complement factor D inhibitor.Formule :C29H28BrN7O3Couleur et forme :SolidMasse moléculaire :602.493Cbl-b-IN-28
Cbl-b-IN-28 (Compound B2) is an orally active Cbl-b inhibitor. It enhances the function of immune cells by promoting the secretion of cytokines like IL-2 and modulating the phosphorylation levels of key proteins in the T cell receptor signaling pathway. Cbl-b-IN-28 is applicable in cancer immunology research.Couleur et forme :Odour SolidAnti-HLA-A2 (Hu8F4)
Anti-HLA-A2 (Hu8F4) is a human-derived monoclonal antibody (mAb) that targets HLA-A2. It is applicable in the study of acute myeloid leukemia. The recommended isotype control is Human IgG1 kappa (Isotype Control).Couleur et forme :Odour LiquidMifamurtide TFA
Mifamurtide TFA: muramyl dipeptide analog, boosts immunity, activates macrophages/monocytes, potential osteosarcoma research.Formule :C61H110F3N6O21PCouleur et forme :SolidMasse moléculaire :1351.52α-Glucosidase/NLRP3-IN-1
α-Glucosidase/NLRP3-IN-1 (Compound 8) acts as a dual inhibitor targeting both α-glucosidase and NLRP3. It features an IC50 value of 6.6 μM for α-glucosidase and inhibits NLRP3 across multiple cell lines at a concentration of 100 μM. This compound demonstrates neuroprotective and antidiabetic properties, making it suitable for related research.Formule :C38H54O4Couleur et forme :SolidMasse moléculaire :574.83SDH-IN-23
SDH-IN-23 (Compound B21) is an SDH inhibitor with exceptional nematicidal activity. It can suppress nematode feeding, reproduction, and embryonic development while also inducing lethal effects through mechanisms such as oxidative stress, intestinal damage, and SDH inhibition.Formule :C19H11ClF6N2O2Couleur et forme :SolidMasse moléculaire :448.75TLR8 agonist 7
CAS :TLR8 agonist7 is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of less than 250 nM. It remains stable in human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist7 demonstrates antitumor activity, achieving a tumor growth inhibition (TGI) rate of 98%.Formule :C54H63N9O16Couleur et forme :SolidMasse moléculaire :1094.13C3 Protein (human)
C3 Protein (human) is an intrinsically glycosylated polypeptide composed of two disulfide-linked chains. Complement protein C3 is a pivotal molecule within the complement system, and its activation is fundamental to all essential functions of this system.Couleur et forme :Odour Solid24-Methylenecholesterol
CAS :24-Methylenecholesterol (24 Methylenecholesterol) is a natural marine sterol, which stimulates cholesterol acyl transferase (ACAT) in human macrophages.Formule :C28H46ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :398.66PIC1 PA TFA
PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.Formule :C71H123N19O21S2·xC2HF3O2Couleur et forme :SolidCridanimod sodium
CAS :Cridanimod boosts PR expression and may help treat endometrial cancer by inhibiting estrogen production.Formule :C15H11NNaO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :276.24Glutaminase C-IN-2
Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), exhibits potent inhibitory activity with an IC50 of 10.64 nM.Formule :C24H23N7O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :473.55Englumafusp alfa
Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion protein combining a CD19-specific antibody domain with trimerized extracellular domains of human 4-1BBL,Couleur et forme :Odour LiquidM-5011
CAS :M-5011: NSAID and immunomodulator for pain and inflammation; ED50 0.63mg/kg; reduces bone loss in arthritis; low ulcer risk.Formule :C14H14O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :246.32Biotin-labeled ODN 1668 sodium
Biotin-labeled ODN 1668 (sodium), a class B CpG oligodeoxynucleotide (ODN) and TLR9 agonist, facilitates the assessment of cellular uptake and localization ofCouleur et forme :Odour Solid6-Amyl-2-pyrone
CAS :6-Amyl-2-pyrone exhibits inhibitory activity against tyrosinase, antibacterial and antiviral activity against Penicillium vulpinum and Aspergillus flavus, and antifungal activity against Sclerotinia sp.Formule :C10H14O2Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :166.22PSMA-IN-1
PSMA-IN-1 (compound 23) is an inhibitor of PSMA with a Ki value of 2.49 nM. It inhibits tumor growth with high selectivity and specificity in PSMA+ tumor models. Additionally, PSMA-IN-1 serves as an NIR (λEX: 620 nm; λEM: 670 nm) dye for tumor imaging. PSMA-IN-1 is utilized in prostate cancer research.Formule :C66H80N10O20Masse moléculaire :1332.55504
