Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(143 produits)
- CXCR(158 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(110 produits)
- IκB/IKK(57 produits)
- LTR(3 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(2 produits)
- NF-κB(386 produits)
- NOD(25 produits)
- NOS(61 produits)
- Nrf2(81 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(60 produits)
- TLR(76 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3435 produits trouvés pour "Immunologie et Inflammation"
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Smcy HY Peptide (738-746)
CAS :Smcy HY Peptide (738-746) is an H2-Db-restricted peptide, derived from the amino acid sequence 738 to 746 of the Smcy protein.Formule :C48H82N18O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1167.34G3-YSD
CAS :G3-YSD is a G3 terminal Y-shaped short DNA and functions as a cyclic guanosine-adenosine monophosphate synthase (cGAS) agonist. It serves as a minimal immunostimulatory DNA motif, capable of activating the DNA sensor cGAS, which induces type I interferon in a manner dependent on structure and sequence. G3-YSD is applicable for detecting HIV-1 single-stranded DNA.Couleur et forme :SolidNOTA-Pep-1L
NOTA-Pep-1L specifically targets the IL13RA2 receptor and is utilized for tumor imaging. Additionally, it is employed in the synthesis and research of radiolabeled conjugates (RDC).Formule :C84H139N27O25S3Masse moléculaire :2021.95976BuChE-IN-20
BuChE-IN-20 is a selective hBuChE inhibitor (IC50= 0.13 μM) with the ability to cross the blood-brain barrier (BBB). This compound, a derivative of L-Tryptophan, exhibits neuroprotective effects by inhibiting nitric oxide (NO) production and reducing reactive oxygen species (ROS) levels. It effectively suppresses the self-aggregation of amyloid-beta (Aβ) peptides and is applicable in Alzheimer's disease research.Couleur et forme :Odour SolidFLY26
FLY26 is a selective partial antagonist of GluN2B, with an IC50 value of 0.64 μM. FLY26 inhibits the GluN2B subunit of NMDA receptors, reducing calcium ion influx and reactive oxygen species (ROS) production. It also activates the BDNF/TrkB/CREB neuroprotective signaling pathway, mitigating excitotoxicity and mitochondrial dysfunction. FLY26 holds potential for treating neurological deficits caused by cerebral ischemia-reperfusion injury.Formule :C22H23N5O3Couleur et forme :SolidMasse moléculaire :405.18009KTX-612
CAS :KTX-612 is a compound that serves as an orally active IRAK4 degrader, exhibiting a DC50 value of 7 nM. It is primarily utilized in oncology research [1].Formule :C46H51F3N8O6Couleur et forme :SolidMasse moléculaire :868.942,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside
CAS :2,4,6-Trichlorol-3-methyl-5-methoxy-phenol 1-O-β-d-glucopyranosyl-(1 → 6)-β-d-glucopyranoside is a chlorophenyl glycoside that is commonly found in the bulbs ofFormule :C20H27Cl3O12Couleur et forme :SolidMasse moléculaire :565.78Immunology/Inflammation Compound Library
A unique collection of xnum anti-inflammation compounds effective for high throughput screening and high content screening.Couleur et forme :Odour SolidRef: TM-L4700
1mgÀ demander30μL*10mM (DMSO)À demander50μL*10mM (DMSO)À demander100μL*10mM (DMSO)À demander250μL*10mM (DMSO)À demanderE7766 disodium
CAS :E7766 disodium, a macrocycle-bridged STING agonist, exhibits a binding affinity (Kd) of 40 nM, demonstrating potent pan-genotypic and antitumor effects.Formule :C24H26F2N10Na2O8P2S2Couleur et forme :SolidMasse moléculaire :792.58(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA
CAS :(6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA ((6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-coenzyme A) acts as an NLRX1 modulator. This compound shows potential for research into immune and metabolism-related diseases.Formule :C45H70N7O17P3SCouleur et forme :SolidMasse moléculaire :1106.06Adrenomedullin (rat)
CAS :Adrenomedullin (rat), a potent vasodilator peptide, is secreted by both endothelial cells (EC) and vascular smooth muscle cells (VSMC) [1].Couleur et forme :SolidChemokine Inhibitor Library
A unique collection of xnum chemokines or chemokine receptors targeted compounds for high throughput and high content screening;
Couleur et forme :Odour SolidSTING agonist-3 trihydrochloride
STING agonist-3 is a selective, non-nucleotide small-molecule with anti-tumor properties and potential in cancer therapy.Formule :C37H45Cl3N12O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :860.19DC 07090
CAS :DC 07090 is a human enterovirus 71 3C protease inhibitor with antiviral activity for the study of nucleic acid virus infections.Formule :C18H14N4ODegré de pureté :97.34%Couleur et forme :SolidMasse moléculaire :302.33Hispaglabridin A
CAS :Hispaglabridin A, an effective antioxidant, inhibits lipid peroxidation [1].Formule :C25H28O4Couleur et forme :SolidMasse moléculaire :392.49Keap1-Nrf2-IN-25
Keap1-Nrf2-IN-25 (Compound 19) is a potent Keap1-Nrf2 inhibitor with an IC50 of 0.55 μM and exhibits a Keap1 binding affinity (Kd of 0.50 μM). This compound activates Nrf2, reducing reactive oxygen species (ROS) and pro-inflammatory cytokines (IL-1β, IL-6). Additionally, Keap1-Nrf2-IN-25 provides protective effects against DSS-induced colitis.Formule :C25H28N2O6SCouleur et forme :SolidMasse moléculaire :484.565Eritoran Tetrasodium
CAS :Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.Formule :C66H122N2Na4O19P2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1401.58ROS inducer 8
ROS inducer 8 (Compound 11g) acts as an inhibitor of glutathione (GSH) and promotes the accumulation of reactive oxygen species (ROS) in Enterococcus faecalis, exhibiting antibacterial properties. It is capable of disrupting biofilms and inhibiting S. aureus and E. faecalis with minimum inhibitory concentrations (MICs) of 8 μg/mL and 2 μg/mL, respectively, demonstrating a post-antibiotic effect. Additionally, ROS inducer 8 shows low hemolytic toxicity on sheep red blood cells with an HC50 greater than 1280 μg/mL.Formule :C26H31FN6O6Couleur et forme :SolidMasse moléculaire :542.56Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.Formule :C78H125N7O42Couleur et forme :SolidMasse moléculaire :1832.85PROTAC IRAK4 degrader-5
CAS :PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.Formule :C41H40F3N11O9Couleur et forme :SolidMasse moléculaire :887.834
