Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(143 produits)
- CXCR(158 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(110 produits)
- IκB/IKK(57 produits)
- LTR(3 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(2 produits)
- NF-κB(386 produits)
- NOD(25 produits)
- NOS(61 produits)
- Nrf2(81 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(60 produits)
- TLR(76 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3433 produits trouvés pour "Immunologie et Inflammation"
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NOD2 agonist 2
NOD2 agonist 2 (compound 23) enhances antigen presentation in murine bone marrow-derived dendritic cells (BMDCs), highlighting its potential as a vaccine adjuvant.Formule :C46H65N3O10Couleur et forme :SolidMasse moléculaire :820.02Vensobafusp alfa
CAS :Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.Couleur et forme :LiquidSIIVFEKL TFA
SIIVFEKL TFA is a variant of the principal MHC class I-restricted epitope, SIINFEKL. This antigenic peptide stimulates specific T cells in experimental settings to study competitive interactions among T cells. SIIVFEKL TFA exhibits lower affinity for the OT-I T cell receptor (TCR) and can be utilized to detect CD8+ T cells.Couleur et forme :Odour SolidTri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH
Tri(TLR4-IN-C34-PEG2/PEG1)-amide-C3-COOH is a TLR4 inhibiting linker, reducing inflammation in endotoxemia and enterocolitis mouse models.Formule :C78H125N7O42Couleur et forme :SolidMasse moléculaire :1832.85Biotin-labeled ODN 2216 sodium
Biotin-labeled ODN 2216 (sodium) serves as a specific agonist for human TLR9 (toll-like receptor 9), facilitating the assessment of CpG ODN cellular uptake andCouleur et forme :Odour SolidAloenin aglycone
CAS :Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate.Formule :C13H12O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.23PROTAC IRAK4 degrader-5
CAS :PROTAC IRAK4 degrader-5 is a Cereblon-based IRAK4 degrader.Formule :C41H40F3N11O9Couleur et forme :SolidMasse moléculaire :887.834TLR8 agonist 8
CAS :TLR8 agonist8 (Compound II-72) is an agonist of Toll-like receptor 8 (TLR8) with an EC50 of 0.25-1 μM. It demonstrates stability in both human and mouse plasma and induces the secretion of the cytokine TNFα with an EC50 of less than 1 μM. In the MC38-HER2 xenograft mouse model, TLR8 agonist8 exhibits antitumor activity, achieving a tumor growth inhibition (TGI) rate of 89%.Formule :C53H63N11O10Couleur et forme :SolidMasse moléculaire :1014.14EX-A5758
CAS :EX-A5758: novel nNOS-NOS1AP inhibitor, reduces pain & enhances paclitaxel's anti-tumor effect.Formule :C10H17NO5Degré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :231.25HNW005
HNW005 is a dual inhibitor targeting the NLRP3 inflammasome and urate transporter 1 (URAT1). It exhibits an inhibition constant (KD) of 204.6 nM and an IC50 of 1.7 μM for NLRP3 inflammasome activation, while demonstrating an IC50 of 6.4 μM for inhibiting uric acid transmembrane transport. At an administered dose of 2 mg/kg in vivo, HNW005 achieves a uric acid reduction rate of 64.8%, effectively providing anti-inflammatory, analgesic, and urate-lowering effects by inhibiting NLRP3 inflammasome activation and uric acid transport. HNW005 is applicable for research in gouty arthritis.Couleur et forme :Odour SolidTimosaponin E2
CAS :Timosaponin E2 is an anti-inflammatory agent that inhibits active oxygen production [1].Formule :C46H78O20Couleur et forme :SolidMasse moléculaire :951.1CTT2274
CTT2274 is a prodrug of MMAE. It consists of a prostate-specific membrane antigen (PSMA) binding scaffold, a biphenyl motif, a pH-sensitive phosphoramidate linker, and an MMAE payload. CTT2274 selectively targets and binds to PSMA to deliver MMAE and has the capability to inhibit prostate cancer.Formule :C119H159N17O33P2Couleur et forme :SolidMasse moléculaire :2417.58Ulevostinag
CAS :Ulevostinag (MK-1454) is a STING agonist.Formule :C20H22F2N10O9P2S2Couleur et forme :SolidMasse moléculaire :710.52Schisanchinin D
CAS :Schisanchinin D is a useful organic compound for research related to life sciences. The catalog number is T125682 and the CAS number is 1614245-13-4.Formule :C23H30O6Couleur et forme :SolidMasse moléculaire :402.487IACS-8803 diammonium
IACS-8803 diammonium, a potent cyclic dinucleotide STING agonist, demonstrates robust systemic antitumor efficacy [1].Formule :C20H29FN12O9P2S2Couleur et forme :SolidMasse moléculaire :726.6Eramkafusp Alfa
Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].Couleur et forme :Odour LiquidSTING agonist-44
STINGagonist-44 (Compound 4) is a potent and selective STING agonist with an EC50 value of 5.68 μM in THP1 cells and 2.212 μM in RAW cells for inducing IRF. It activates the STING pathway, leading to the production of type I interferons and pro-inflammatory cytokines (e.g., CXCL10, TNFα). STINGagonist-44 holds promise for cancer research.Couleur et forme :Odour Solid3-Hydroxykynurenamine
CAS :3-Hydroxykynurenamine (3-HKA) is a tryptophan metabolite with anti-inflammatory effects, reducing cytokines and aiding in models of psoriasis and nephritis.Formule :C9H12N2O2Couleur et forme :SolidMasse moléculaire :180.2OVA peptide
CAS :Ovalbumin (OVA) peptide, primarily found in egg white, is a class I (Kb)-restricted peptide epitope presented by H-2Kb, the mouse MHC (major histocompatibilityFormule :C74H121N27O24Masse moléculaire :1772.92MSA-2-Pt
MSA-2-Pt is an orally active STING agonist with excellent cell membrane permeability. It can induce cell death via Pt, releasing damaged DNA to activate the cGAS-STING pathway. Additionally, MSA-2-Pt can directly activate the STING pathway through MSA-2. This compound is applicable in cancer research.Formule :C28H32N2O10PtS2Masse moléculaire :815.11463
