Immunologie et Inflammation
Les inhibiteurs en immunologie et inflammation sont des composés qui modulent la réponse immunitaire et les processus inflammatoires. Ces inhibiteurs sont cruciaux pour étudier les mécanismes de la régulation immunitaire, l'auto-immunité et l'inflammation chronique, ainsi que pour développer des traitements pour les maladies inflammatoires, les allergies et les troubles immunitaires. En ciblant des voies clés du système immunitaire, ces inhibiteurs peuvent aider à réduire les réponses immunitaires excessives ou inappropriées. Chez CymitQuimica, nous offrons une large sélection d'inhibiteurs de haute qualité en immunologie et inflammation pour soutenir vos recherches en immunologie, inflammation et développement thérapeutique.
Sous-catégories appartenant à la catégorie "Immunologie et Inflammation"
- RCC(143 produits)
- CXCR(158 produits)
- Paroi cellulaire(5 produits)
- Récepteur IL(105 produits)
- IκB/IKK(58 produits)
- LTR(3 produits)
- MALT(25 produits)
- MRP(6 produits)
- NADPH-oxydase(2 produits)
- NF-κB(389 produits)
- NOD(25 produits)
- NOS(61 produits)
- Nrf2(82 produits)
- PGE Synthase(31 produits)
- ROS(70 produits)
- TGF-beta/Smad(59 produits)
- TLR(74 produits)
- Thioredoxine(12 produits)
- gp120/CD4(4 produits)
Affichez 11 plus de sous-catégories
3397 produits trouvés pour "Immunologie et Inflammation"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
IL-1β-IN-1
CAS :IL-1β-IN-1, a cannabidiol derivative, acts as a potent inhibitor of IL-1β, exhibiting significant anti-inflammatory and pain relief properties [1].Formule :C22H34O2Couleur et forme :SolidMasse moléculaire :330.5UNC8900
UNC8900 is a VHL-recruiting STINGPROTAC degrader with a DC50 of 0.924 μM. It is applicable for the study of bacterial and viral infections.Formule :C75H99N17O15SMasse moléculaire :1509.72273GS-9191 PM
GS-9191 PM: novel antitumorviral bis-amide prodrug, inhibits MDR1/BCRP, has antiproliferative activity.Formule :C11H16N6ODegré de pureté :99.79%Couleur et forme :SoildMasse moléculaire :248.28Galectin-8-IN-2
CAS :Galectin-8-IN-2 (Compound 10) acts as an inhibitor of galectin-8N [1].Formule :C15H20O7Couleur et forme :SolidMasse moléculaire :312.32N188 TFA
N188 TFA is a radiolabeled ligand based on a bicyclic peptide scaffold, targeting the protein nectin-4, which is overexpressed in various tumors. It can be efficiently labeled with the radioactive isotope 68Ga to form 68Ga-N188, suitable for positron emission tomography (PET) imaging. The development of N188 TFA and its radiolabeled form, 68Ga-N188, holds potential for the diagnosis and treatment of cancers such as urothelial carcinoma.Couleur et forme :Odour SolidIFN-γ Antagonist 1
CAS :IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI), an interferon γ (IFN γ) antagonist, effectively inhibits IFN-γ induced HLR/DR antigen expression in Colon 205 cellsFormule :C115H194N34O34SCouleur et forme :SolidMasse moléculaire :2629.04Antitumor agent-185
Antitumor agent-185 (compound 3) exhibits significant antitumor effects, effectively inhibiting tumor growth and extending the survival period of mice in vivo.Formule :C109H199N5O36P2Couleur et forme :SolidMasse moléculaire :2217.71BQ7859
BQ7859 is a probe designed to target PSMA, equipped with a NOTA chelator, offering exceptional imaging capabilities. It can be labeled with various radionuclides such as [68Ga], [18F], [55Co], and [111In]. In mouse prostate cancer xenograft models, BQ7859 (labeled with [111In]) effectively accumulates in tumor regions through a PSMA-dependent mechanism, providing high-contrast tumor imaging. This compound holds promise for research in prostate cancer imaging, particularly in the areas of positron emission tomography (PET) and single-photon emission computed tomography (SPECT). Additionally, BQ7859 can be used in the synthesis or study of radionuclide conjugate drugs (RDC).Formule :C62H89N11O18Couleur et forme :SolidMasse moléculaire :1276.43Nasunin
CAS :Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.Formule :C42H47ClO23Couleur et forme :SolidMasse moléculaire :955.26cGAS-IN-3
cGAS-IN-3 (compound 30d-S) is an orally active inhibitor of cyclic GMP-AMP synthase (cGAS) that exhibits excellent plasma exposure and low clearance rate. It demonstrates anti-inflammatory properties, significantly reducing pulmonary inflammation in rats.Formule :C21H20Cl2F2N4O2Masse moléculaire :468.09314BNTA
CAS :BNTA is a potent extracellular matrix (ECM) modulator.Formule :C17H11BrClNO3S2Degré de pureté :99.79% - 99.82%Couleur et forme :SolidMasse moléculaire :456.76Ref: TM-T40795
1mg87,00€5mg178,00€1mL*10mM (DMSO)178,00€10mg295,00€25mg573,00€50mg802,00€100mg1.099,00€500mg2.205,00€Noraramtide
CAS :Noraramtide (BHV-1100) is an antibody recruiting molecule that specifically binds to the CD38 molecule to recruit natural killer (NK) cells. This interaction enhances the NK cells' ability to kill tumor cells through antibody-dependent cellular cytotoxicity (ADCC). This mechanism allows NK cells to more effectively recognize and eliminate tumor cells while preventing mutual NK cell destruction. Noraramtide is utilized in research on autologous cancer immunotherapy.Formule :C210H300N48O65S3Couleur et forme :SolidMasse moléculaire :4633.11OT-551 HCl
CAS :OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macularFormule :C13H24ClNO3Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :277.79Ref: TM-T28273L
1mg109,00€5mg233,00€1mL*10mM (DMSO)279,00€10mg344,00€25mg532,00€50mg760,00€100mg1.054,00€200mg1.414,00€Nrf2 degrader 1
CAS :Nrf2 degrader 1 (compound 1), a PROTAC Nrf2 degrader, exhibits anticancer properties by inhibiting the growth of cancer cells. It demonstrates IC 50 values of 100 nM for A549 cells and 40 nM for LK-2 cells, indicating potent efficacy [1].Formule :C45H42N6O8SCouleur et forme :SolidMasse moléculaire :826.92Anti-inflammatory agent 62
Anti-inflammatory agent 62 mitigates acetaminophen-induced hepatotoxicity in HepG2 cells by modulating inflammatory and oxidative stress pathways [1].Couleur et forme :Odour SolidBivalirudin TFA
CAS :Bivalirudin TFA, a 20-residue synthetic peptide, reversibly inhibits thrombin, affecting platelet aggregation and thrombin generation.Formule :C98H138N24O33·C2HF3O2Couleur et forme :SolidMasse moléculaire :2294.34IKZF3 degrader 1
IKZF3 Degrader 1 (compound 19a) acts as an effective IKZF3 degrader with an EC50 of 0.012 μM and a minimal yield of 9.2%. It enhances the association of IKZF3 with Cereblon (CRBN), subsequently facilitating the ubiquitination and degradation of IKZF3.Formule :C25H18BrCl3N2O5Couleur et forme :SolidMasse moléculaire :612.68NLRP3-IN-63
CAS :NLRP3-IN-63 (Compound 7) is an inhibitor of NLRP3, effectively suppressing NLRP3 activation with an EC50 of 13 nM.Formule :C20H22F3N5OCouleur et forme :SolidMasse moléculaire :405.42NP3-253
CAS :NP3-253 is an orally active NLRP3 inhibitor that can cross the blood-brain barrier. It serves as a tool for further exploring the biological properties of NLRP3 in models of peripheral and neuroinflammation.Formule :C19H23F3N4OCouleur et forme :SolidMasse moléculaire :380.41FV-100
CAS :FV-100 (Valnivudine HCl), API for CF-1743, is a potent, oral anti-vaxx-zoster drug with low in vivo toxicity.Formule :C27H36ClN3O6Degré de pureté :98.52%Couleur et forme :SolidMasse moléculaire :534.04
