NF-κB
Le facteur nucléaire kappa B (NF-κB) est un facteur de transcription qui régule l'expression des gènes impliqués dans les réponses immunitaires, l'inflammation, la survie cellulaire et la prolifération. Le NF-κB est activé en réponse à divers stimuli, y compris les cytokines, les agents pathogènes et les signaux de stress. La dérégulation de la signalisation du NF-κB est associée à des maladies inflammatoires chroniques, au cancer et aux troubles auto-immuns. Chez CymitQuimica, nous offrons une sélection complète de modulateurs de la voie NF-κB pour soutenir vos recherches en inflammation, oncologie et régulation immunitaire.
445 produits trouvés pour "NF-κB"
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BAY-985
CAS :<p>BAY-985: potent oral TBK1/IKKε inhibitor; IC50s: TBK1 (2/30 nM), IKKε (2 nM); has antitumor properties.</p>Formule :C27H30F3N9ODegré de pureté :99.62%Couleur et forme :SolidMasse moléculaire :553.58Sodium salicylate
CAS :<p>Sodium salicylate (2-Hydroxybenzoic acid sodium salt), a metabolite of acetylsalicylic acid, can inhibit NF-kB and reduce oxidative stress.</p>Formule :C7H5NaO3Degré de pureté :99.36% - 99.92%Couleur et forme :White Solid AmorphousMasse moléculaire :160.11Sulfasalazine
CAS :<p>Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.</p>Formule :C18H14N4O5SDegré de pureté :98.00% - 99.28%Couleur et forme :Minute Brownish-Yellow CrystalsMasse moléculaire :398.39Theophylline monohydrate
CAS :<p>Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium</p>Formule :C7H8N4O2·H2ODegré de pureté :99.78%Couleur et forme :SolidMasse moléculaire :198.184-Hydroxychalcone
CAS :<p>4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.</p>Formule :C15H12O2Degré de pureté :99.75%Couleur et forme :Yellow PowderMasse moléculaire :224.25DRI-C21045
CAS :<p>Dri-c21045 inhibits NF-kB (IC50=17.1μM) and B cell proliferation (IC50=4.5μM), selectively blocking CD40-CD40L interaction (IC50=0.17μM).</p>Formule :C32H24N2O7SDegré de pureté :97.20%Couleur et forme :SolidMasse moléculaire :580.61Theophylline
CAS :<p>Theophylline (1,3-Dimethylxanthine) is a methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central</p>Formule :C7H8N4O2Degré de pureté :99.65% - 99.98%Couleur et forme :White Solid PowderMasse moléculaire :180.16AZ1495
CAS :<p>AZ1495: oral IRAK4 inhibitor (IC50: 5 nM), IRAK1 (23 nM), treats MYD88L265P DLBCL.</p>Formule :C21H31N5O2Degré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :385.5TBK1/IKKε-IN-2
CAS :<p>TBK1/IKKε-IN-2 is a dual inhibitor of TBK1 and IKKε.</p>Formule :C26H27N5O3Degré de pureté :98.89%Couleur et forme :SolidMasse moléculaire :457.52GLPG2534
CAS :<p>GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 can be used in psoriasis and atopic dermatitis.</p>Formule :C21H24N6O4Degré de pureté :99.51% - 99.61%Couleur et forme :SolidMasse moléculaire :424.45Articaine hydrochloride
CAS :<p>Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.</p>Formule :C13H21ClN2O3SDegré de pureté :99.76%Couleur et forme :White Crystalline PowderMasse moléculaire :320.84Urolithin B
CAS :<p>Urolithin B is one of the gut microbial metabolites of ellagitannins and is found in diverse plant foods, including pomegranates, berries, walnuts, tropical</p>Formule :C13H8O3Degré de pureté :99.45%Couleur et forme :SolidMasse moléculaire :212.2Dihydroartemisinin
CAS :<p>Dihydroartemisinin (Artenimol) is an antimalarial drug. High-Quality, Low-Cost!</p>Formule :C15H24O5Degré de pureté :98% - 99.41%Couleur et forme :White SolidMasse moléculaire :284.35Aspirin
CAS :<p>Aspirin (Acetylsalicylic Acid) is a COX inhibitor. Aspirin has anti-inflammatory, antipyretic and analgesic activities. Cost-effective and quality-assured.</p>Formule :C9H8O4Degré de pureté :99.78% - 99.91%Couleur et forme :White Solid CrystallineMasse moléculaire :180.16DCZ0415
CAS :<p>DCZ0415: Potent TRIP13 inhibitor; combats myeloma in vitro, in vivo, and in drug-resistant patients; hinders DNA repair and NF-κB activity.</p>Formule :C23H20N2O2Degré de pureté :99.34% - 99.95%Couleur et forme :SolidMasse moléculaire :356.42CDDO-dhTFEA
CAS :<p>CDDO-dhTFEA, a synthetic oleanane triterpenoid, effectively activates Nrf2 while inhibiting the NF-κB pro-inflammatory transcription factor.</p>Formule :C33H45F3N2O3Degré de pureté :95.61% - 99.59%Couleur et forme :SolidMasse moléculaire :574.72IMD-0560
CAS :<p>IMD-0560 is a novel inhibitor of IκB kinase β.</p>Formule :C15H8BrF6NO2Degré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :428.12Methylthiouracil
CAS :<p>Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and it is used to treat hyperthyroidism.</p>Formule :C5H6N2OSDegré de pureté :99.89% - >99.99%Couleur et forme :Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)Masse moléculaire :142.18Lidocaine Hydrochloride hydrate
CAS :<p>Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.</p>Formule :C14H22N2O·HCl·H2ODegré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :288.82Mevastatin
CAS :<p>Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum.</p>Formule :C23H34O5Degré de pureté :99.12%Couleur et forme :White-Yellowish To Yellow Powder Solid PowderMasse moléculaire :390.51Asatone
CAS :<p>Asatone from Radix et Rhizoma Asari has anti-inflammatory properties, acting on NF-κB and suppressing p-MAPK pathways (ERK, JNK, p38).</p>Formule :C24H32O8Degré de pureté :99.84% - 99.92%Couleur et forme :SolidMasse moléculaire :448.51Lidocaine hydrochloride
CAS :<p>Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.</p>Formule :C14H23ClN2ODegré de pureté :99.81% - 99.92%Couleur et forme :White Crystal PowderMasse moléculaire :270.798(E/Z)-BCI
CAS :<p>(E/Z)-BCI (NSC-150117), a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory properties, reduces LPS-induced inflammatory mediators and ROS</p>Formule :C22H23NODegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :317.42Oxaprozin
CAS :<p>Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.</p>Formule :C18H15NO3Degré de pureté :98.53%Couleur et forme :SolidMasse moléculaire :293.32NIK SMI1
CAS :<p>NIK SMI1 is an effective and selective NF-κB inducing kinase (NIK) inhibitor. It also inhibits NIK-catalyzed hydrolysis of ATP to ADP (IC50: 0.23±0.17 nM).</p>Formule :C20H19N3O4Degré de pureté :99.04% - 99.99%Couleur et forme :SolidMasse moléculaire :365.38Naringin dihydrochalcone
CAS :<p>Naringin dihydrochalcone (Naringin DC) is an inhibitor of CYP enzymes, used as an artificial sweetener.</p>Formule :C27H34O14Degré de pureté :99.07% - 99.73%Couleur et forme :Solid PowderMasse moléculaire :582.55IRAK4-IN-4
CAS :<p>IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4)</p>Formule :C22H16N2O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :340.37Metaxalone
CAS :<p>Metaxalone, sold as Skelaxin by King Pharmaceuticals, is a muscle relaxant for pain from strains and sprains.</p>Formule :C12H15NO3Degré de pureté :98.84% - 99.94%Couleur et forme :White To Almost White Crystalline Powder SolidMasse moléculaire :221.25Mangiferin
CAS :<p>Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.</p>Formule :C19H18O11Degré de pureté :99.78% - 99.86%Couleur et forme :Light Yellow PowderMasse moléculaire :422.34Baicalin
CAS :<p>Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIV</p>Formule :C21H18O11Degré de pureté :90.08% - 99.32%Couleur et forme :Yellow PowderMasse moléculaire :446.365-Aminosalicylic Acid
CAS :<p>5-Aminosalicylic Acid (5-ASA) is a specific PPARγ agonist and also inhibits P21-activated kinase 1 (PAK1) and NF-Κb. High-Quality, Low-Cost!</p>Formule :C7H7NO3Degré de pureté :98.88% - 99.49%Couleur et forme :Purplish-Tan Solid PowderMasse moléculaire :153.14Sulindac
CAS :<p>Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.</p>Formule :C20H17FO3SDegré de pureté :99.09% - 99.15%Couleur et forme :Yellow SolidMasse moléculaire :356.41Lidocaine
CAS :<p>Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.</p>Formule :C14H22N2ODegré de pureté :99.95% - >99.99%Couleur et forme :Needles From Benzene Or Alcohol SolidMasse moléculaire :234.34Nimbolide
CAS :<p>Nimbolide, from neem, inhibits CDK4/6, NF-κB, Wnt, PI3K-Akt, MAPK, JAK-STAT pathways and induces apoptosis.</p>Formule :C27H30O7Degré de pureté :95.84% - 99.4%Couleur et forme :SolidMasse moléculaire :466.52α-Lipoic Acid
CAS :<p>α-Lipoic Acid, a sulfur-containing octanoic acid derivative, is biosynthesized from linoleic acid and used in dietary supplements.</p>Formule :C8H14O2S2Degré de pureté :98.39% - 99.73%Couleur et forme :Forms Yellowish Flakes Light Yellow To Yellow PowderMasse moléculaire :206.33Ergolide
CAS :<p>Ergolide, from Inula Britannica, inhibits iNOS and COX-2 by deactivating NF-κB in macrophages.</p>Formule :C17H22O5Degré de pureté :99.64%Couleur et forme :SolidMasse moléculaire :306.35Erdosteine
CAS :<p>Erdosteine (RV 144), a mucolytic thiol, modulates mucus and aids expectoration, reduces cough, and protects lungs from smoke damage.</p>Formule :C8H11NO4S2Degré de pureté :99.43% - 99.94%Couleur et forme :White Or Almost White Crystalline PowderMasse moléculaire :249.31Indacaterol maleate
CAS :<p>Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.</p>Formule :C28H32N2O7Degré de pureté :99.03% - 99.67%Couleur et forme :SolidMasse moléculaire :508.56Guaiacol
CAS :<p>Guaiacol, a flavorant precursor, has medicinal uses and serves as an oxygen indicator turning yellow-brown at 470 nm.</p>Formule :C7H8O2Degré de pureté :99.95%Couleur et forme :Colourless To Pale Yellow Solid CrystallineMasse moléculaire :124.14GSK3145095
CAS :<p>GSK3145095 is an orally active inhibitor of RIPK1 with IC50 of 5 nM, with potential immunomodulatory activities and antineoplastic.</p>Formule :C20H17F2N5O2Degré de pureté :99.50%Couleur et forme :SolidMasse moléculaire :397.38RIPK1-IN-7
CAS :<p>RIPK1-IN-7: Strong, selective RIPK1 inhibitor (Kd=4 nM, IC50=11 nM) with great antimetastasis effects in B16 melanoma.</p>Formule :C25H22F3N5O2Degré de pureté :98.02% - 98.18%Couleur et forme :SolidMasse moléculaire :481.47SN50 acetate (213546-53-3 free base)
<p>SN50 acetate is a cell permeable inhibitor of NF-κB translocation.</p>Formule :C131H234N36O31SDegré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :2841.55Sinomenine hydrochloride
CAS :<p>Sinomenine hydrochloride (Kukoline hydrochloride) is extracted from Sinomenium Acutum Rehderett Wilson.</p>Formule :C19H24ClNO4Degré de pureté :99.43%Couleur et forme :SolidMasse moléculaire :365.851DMAPT
CAS :<p>DMAPT is a water-soluble PTL analogue, orally active NF-κB inhibitor with 1.7 μM LD50 in acute myeloid leukemia cells.</p>Formule :C17H27NO3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :293.4MJ210
<p>MJ210 is an orally active and blood-brain barrier-permeable modulator of the NF-κB and MAPK pathways, exhibiting neuroprotective properties. In vitro, 5 μM MJ210 can increase the survival rate of rotenone-treated SH-SY5Y cells to 81.9% and reduce levels of ROS. In vivo, 5 mg/kg MJ210 improves motor dysfunction in rat models of Parkinson's disease. MJ210 is useful for research in neurological disorders, including Parkinson's disease.</p>Couleur et forme :Odour SolidTranscription Factor-Targeted Compound Library
<p>Well-chosen xnum compounds with unique structures targeting transcription factor;</p>Couleur et forme :Odour SolidGliotoxin
CAS :<p>Gliotoxin, a mycotoxin, inhibits Wnt pathway, causing apoptosis in mutated colorectal cancer cells and blocks NF-κB by preserving IκB.</p>Formule :C13H14N2O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :326.39Ginger extract
CAS :<p>Ginger extract demonstrates (exhibits) anti-cancer, anti-inflammatory, and chemotherapeutic properties in living organisms (in vivo).</p>Couleur et forme :SolidHelenalin
CAS :<p>Helenalin: anti-inflammatory sesquiterpene, inhibits NF-κB by alkylating p65 cysteine groups, blocks DNA binding.</p>Formule :C15H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.312-Oxo phytodienoic acid
CAS :<p>12-oxo PDA boosts alkaloid production in E. californica, enhances B. dioica tendril curls, and blocks JA-induced cell death in A. fru mutants.</p>Formule :C18H28O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :292.41OT-551 HCl
CAS :<p>OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular</p>Formule :C13H24ClNO3Degré de pureté :99.71%Couleur et forme :SolidMasse moléculaire :277.79CAY10657
CAS :<p>CAY10657 has a wide range of applications in life science related research.</p>Formule :C17H20N4O3SCouleur et forme :SolidMasse moléculaire :360.43CIB-1476
<p>CIB-1476, a caspase-1 inhibitor, effectively reduces joint swelling in mouse models of arthritis and demonstrates lasting anti-inflammatory effects. This compound achieves its benefits by blocking IL-1β production, NF-κB activation, and GSDMD-mediated pyroptosis, all of which are triggered by the NLRP3 inflammasome.</p>Formule :C28H28N2O6SCouleur et forme :SolidMasse moléculaire :520.6IKK-IN-3
CAS :<p>IKK-IN-3: potent IKK2 inhibitor (IC50=19nM), affects IKK1(IC50=400nM).</p>Formule :C17H17N5SCouleur et forme :SolidMasse moléculaire :323.427-O-Methylaloeasinol
CAS :<p>7-O-Methylaloeasinol is a useful organic compound for research related to life sciences. The catalog number is T126468 and the CAS number is 105317-69-9.</p>Formule :C20H26O9Couleur et forme :SolidMasse moléculaire :410.419Cyclo(L-Pro-L-Val)
CAS :<p>Cyclo(L-Pro-L-Val), from Mycobacterium spp., has anti-inflammatory effects, hinders phytopathogens, and suppresses IKKα, NF-κB, iNOS, and COX-2 activation.</p>Formule :C10H16N2O2Degré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :196.25Licoagrochalcone C
CAS :<p>Licoagrochalcone C, a flavonoid, inhibits NF-κB and NO production effectively.</p>Formule :C21H22O5Couleur et forme :SolidMasse moléculaire :354.4Anti-inflammatory agent 7
<p>Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.</p>Formule :C36H40N4O9Couleur et forme :SolidMasse moléculaire :672.72Aloenin aglycone
CAS :<p>Aloenin aglycone (compound 13), an inhibitor of NF-κB, can be sourced from aloe exudate.</p>Formule :C13H12O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :248.2317-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic Acid
CAS :<p>DPA metabolite 17-oxo-DPA, found in fish oil, spurs antioxidant genes, modulates inflammation, and activates PPARγ (EC50 ≈ 200 nM).</p>Formule :C22H32O3Couleur et forme :SolidMasse moléculaire :344.495COX-2-IN-48
<p>COX-2-IN-48 (5-25) serves as an inhibitor of COX-2, exhibiting an IC50 of 51.7 nM against human COX-2. It displays anti-inflammatory and analgesic effects in various rodent models through inhibition of the NF-κB pathway. COX-2-IN-48 (5-25) inhibits the degradation of IκB, phosphorylation and nuclear translocation of NF-κB p65, and the expression of COX-2 and iNOS.</p>Couleur et forme :Odour SolidR1-ICR-5
CAS :<p>R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-κB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.</p>Formule :C54H70N8O7S2Couleur et forme :SolidMasse moléculaire :1007.31SN50 TFA
<p>SN50 TFA is an inhibitor of NF-κB and attenuates alveolar hypercoagulation and fibrinolysis inhibition. SN50 TFA can be used in studies about ARDS.</p>Formule :C129H230N36O29S·XCF3COOHCouleur et forme :SolidMasse moléculaire :2781.5 (free base)N-Acetyldopamine dimer-2
CAS :<p>Compound 2, an N-acetyldopamine dimer from Periostracum Cicadae, exhibits antioxidant and anti-inflammatory properties.</p>Formule :C20H20N2O6Couleur et forme :SolidMasse moléculaire :384.38Salicortin
CAS :<p>Salicortin, a phenolic glycoside from Populus and Salix, has anti-adipogenic, anti-amnesic, and immune effects.</p>Formule :C20H24O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :424.40NLRP3-IN-51
<p>NLRP3-IN-51 (Compound 3q) is an effective activator of the cholinergic anti-inflammatory pathway (CAP). This compound demonstrates potential for treating gouty arthritis as it inhibits the production of IL-1β in THP-1 cells induced by monosodium urate (MSU). Furthermore, NLRP3-IN-51 suppresses the phosphorylation of NF-κBp65 triggered by MSU without impacting the self-cleavage and activation of NLRP3, pro-caspase 1, or the second messenger caspase-1. Therefore, the initial stage of NLRP3 inhibition by NLRP3-IN-51 occurs through the activation of CAP.</p>Couleur et forme :Odour Solid3-(2-Hydroxyethyl) thio withaferin A
<p>3-(2-Hydroxyethyl) thio withaferin A, a steroidal lactone, blocks NF-kB, targets vimentin, and inhibits EPCR shedding.</p>Formule :C30H44O7SCouleur et forme :SolidMasse moléculaire :548.73RIPK1-IN-25
<p>RIPK1-IN-25 (WL8) is a RIPK1 inhibitor with blood-brain barrier permeability, displaying an EC50 of 19.9 nM and a Kd of 25 nM. It is utilized in the research of neurodegenerative diseases.</p>Couleur et forme :Odour SolidSU1261
<p>SU1261, an IKK inhibitor, exhibits Ki values of 10 nM for IKKα and 680 nM for IKKβ. It effectively inhibits non-canonical NF-κB signaling in U2OS osteosarcoma cells.</p>Couleur et forme :Odour SolidDiprovocim-1
CAS :<p>Diprovocim-1: TLR1/2 agonist; triggers TNF-α in THP-1 cells; boosts ovalbumin IgG1 & CTLs against tumors with anti-PD-L1 in mice.</p>Formule :C56H56N6O6Couleur et forme :SolidMasse moléculaire :909.1Siegesbeckialide I
<p>Siegesbeckialide I effectively suppresses LPS-induced NO production in RAW264.7 murine macrophages by directly interacting with IKKα/β.</p>Formule :C20H28O6Couleur et forme :SolidMasse moléculaire :364.43Pratensein
CAS :<p>Pratensein as a novel transcriptional up-regulator of scavenger receptor class B type I in HepG2 cells.</p>Formule :C16H12O6Degré de pureté :99.90%Couleur et forme :SolidMasse moléculaire :300.26SjDX5-271
CAS :<p>SjDX5-271 is a 3 kDa peptide that inhibits the TLR4/MyD88/NF-κB signaling pathway. It induces cell polarization, alleviates liver inflammation, and protects mice from liver ischemia-reperfusion injury.</p>Formule :C137H215N47O49SCouleur et forme :SolidMasse moléculaire :3336.52RIPK2-IN-5
CAS :<p>RIPK2-IN-5 is a receptor-interacting protein kinase 2 (RIPK2) inhibitor with potential anti-inflammatory activity for the study of diseases caused by immune dysfunctions.</p>Formule :C21H14N4SDegré de pureté :98.85%Couleur et forme :SoildMasse moléculaire :354.43IRAK4-IN-26
<p>IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral bioavailability of 21%.</p>Formule :C22H23N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :405.45(−)-N-Hydroxyapiosporamide
CAS :<p>(−)-N-Hydroxyapiosporamide (NHAP), an alkaloid, serves as an NF-κB inhibitor and demonstrates significant antitumor activity both in vitro and in vivo.</p>Formule :C24H31NO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :445.51CTP-NBD
CAS :<p>CTP-NBD is a cell-permeable, specific inhibitor of the NFκB peptide, which has been utilized in studies of colitis [1] [2].</p>Formule :C121H194N46O32Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2805.12NF-κB-IN-10
<p>NF-κB-IN-10 (compound E1) is an inhibitor of NF-κB that mitigates heart failure symptoms through the modulation of the Nrf2/NF-κB signaling pathway, alleviating</p>Formule :C26H30N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.53IVMT-Rx-3
<p>IVMT-Rx-3 is a chemical compound that serves as an inhibitor of SDCBP's targeting of the PDZ1 and PDZ2 domains of MDA-9/Syntenin.</p>Formule :C69H90F3N13O24Degré de pureté :98%Couleur et forme :SoildMasse moléculaire :1542.54RIPK2/3-IN-1
<p>RIPK2/3-IN-1 is a potent inhibitor of both RIPK2 and RIPK3 kinases, exhibiting IC50 values of 3 nM for RIPK2 and 117 nM for RIPK3.</p>Formule :C24H16N4O2S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :456.54NF-κB-IN-12
<p>NF-κB-IN-12 (compound 3h) serves as a potent inhibitor of NF-κB, exhibiting an IC50 value of 1.02 μM. It is applicable for research in acute lung injury [1].</p>Formule :C30H26N6O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :582.63Sanggenon A
CAS :<p>Sanggenon A (Sanggenone A) exhibits anti-inflammatory properties by modulating the NF-κB and HO-1/Nrf2 signaling pathways in BV2 and RAW264.7 cells, and it</p>Formule :C25H24O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :436.45Narlumosbart
CAS :<p>Narlumosbart (JMT103) is an IgG4κ monoclonal antibody that selectively binds to the receptor activator of nuclear factor-κB ligand (RANKL)[1].</p>Degré de pureté :98%Couleur et forme :LiquidIRAK4-IN-25
<p>IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance (Cl = 12 mL/min/kg), effectively suppresses pro-inflammatory</p>Formule :C23H25N5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :435.48Anti-osteoporosis agent-4
<p>Anti-osteoporosis agent-4 (Compound 11h) suppresses the differentiation of primary osteoclasts and attenuates RANKL-induced osteoclastogenesis.</p>Formule :C26H26ClN3O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :560.02Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Degré de pureté :98%Couleur et forme :Odour SolidHOIPIN-1
CAS :<p>HOIPIN-1 (JTP0819958) is a selective and potent inhibitor of linear ubiquitin chain assembly complex (LUBAC) (IC50 >2.8 μM).HOIPIN-1 inhibits LUBAC-mediated NF-</p>Formule :C17H13NaO4Degré de pureté :98.83%Couleur et forme :SoildMasse moléculaire :304.27TBK1/IKKε-IN-6
CAS :<p>TBK1/IKKε-IN-6 (example 110) is a potent inhibitor of TBK1 and IKKε, with IC50 values of less than 100 nM for both enzymes.</p>Formule :C31H36F2N8O4Couleur et forme :SolidMasse moléculaire :622.678Anti-osteoporosis agent-8
<p>Anti-osteoporosis agent-8 (Compound 4aa) is a RANKL inhibitor, capable of preventing RANKL-induced osteoclastogenesis and osteoclast differentiation, with an IC50 of 2.41 μM. Furthermore, Anti-osteoporosis agent-8 has been shown to mitigate bone loss in an ovariectomized (OVX) mouse model.</p>Formule :C18H19F3N2O2SeMasse moléculaire :432.05638NBD peptide
CAS :<p>NBD peptide inhibits the NF-κB signaling pathway by preventing the binding of the NEMO-IKK complex. It exhibits anti-inflammatory activity by blocking the production of pro-inflammatory cytokines. Additionally, NBD peptide demonstrates immunosuppressive effects through the regulation of immune cells. It enhances transmembrane capacity by conjugating with the cell-penetrating peptide HIV-TAT.</p>Formule :C62H88N14O20Couleur et forme :SolidMasse moléculaire :1349.44NF-κB Signaling Compound Library
<p>A unique collection of xnum compounds targeting NF-κB signaling for high throughput screening and high content screening;</p>Couleur et forme :Odour SolidIRAK4-IN-24
<p>IRAK4-IN-24 (compound 16), a potent IRAK4 inhibitor, exhibits high clearance (Cl) and low oral bioavailability.</p>Formule :C19H19N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :365.39Anti-inflammatory agent 48
<p>Anti-inflammatory agent 48 functions by inhibiting the NF-κB signaling pathway and activating HO-1 expression, characterizing its role as an anti-inflammatory</p>Formule :C24H21Cl2NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :442.33NF-κB-IN-9
<p>NF-κB-IN-9, a nuclear factor kappa B (NF-κB) targeting sonosensitizer with excitation and emission wavelengths (λex/λem) of 489/628 nm, features dual</p>Formule :C62H50N4O4SCouleur et forme :SolidMasse moléculaire :947.15Sootepin D
CAS :<p>Sootepin D is a triterpene from the apical bud of Gardenia sootepensis, and is TNF-α-induced NF-κB inhibitor(IC50 of 8.3μM),with anti-inflammatory activity.</p>Formule :C31H48O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :484.71Murrayafoline A
CAS :<p>Murrayafoline A is a useful organic compound for research related to life sciences. The catalog number is T124835 and the CAS number is 4532-33-6.</p>Formule :C14H13NOCouleur et forme :SolidMasse moléculaire :211.264TH023
<p>TH023 is an inhibitor of the TLR4 signaling pathway, specifically targeting the formation of TLR4 homodimers. In HEK-Blue hTLR4 cells, TH023 suppresses the secretion of embryonic alkaline phosphatase with an IC50 of 0.354 μM and inhibits NO expression in RAW264.7 cells, with an IC50 of 1.61 μM. Additionally, TH023 inhibits the activation of NF-κB and reduces the nuclear translocation of NF-κB p65. The compound demonstrates anti-inflammatory effects in a mouse model of LPS-induced acute sepsis and improves lung injury in mice.</p>Formule :C22H21ClF2N4OCouleur et forme :SolidMasse moléculaire :430.88MRT67307
CAS :<p>Through its effects on ULK1 and ULK2, MRT67307 blocks autophagy.</p>Formule :C26H36N6O2Degré de pureté :99.25% - 99.84%Couleur et forme :SolidMasse moléculaire :464.6HS-243
CAS :<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Formule :C17H16N4O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :324.33CAY10512
CAS :<p>CAY10512, a resveratrol analog, is 100x more potent, inhibiting NF-κB with an IC50 of 0.15 μM versus resveratrol's 20 μM.</p>Formule :C15H13FOCouleur et forme :SolidMasse moléculaire :228.266PS 1145 dihydrochloride
CAS :<p>IκB kinase (IKK) inhibitor</p>Formule :C17H13Cl3N4ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :395.67Nasunin
CAS :<p>Delphanin, also known as Nasunin, is an anthocyanin isolated as purple colored crystals from eggplant peels.</p>Formule :C42H47ClO23Couleur et forme :SolidMasse moléculaire :955.26IKKγ NBD Inhibitory Peptide
CAS :<p>A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF</p>Formule :C170H259N49O42S1Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3693.3EN450
CAS :<p>EN450 is a targeted cysteine degrader of NF-κB with antiproliferative activity and potential anticancer activity for the study of leukemia.</p>Formule :C11H13ClN2O3SDegré de pureté :99.72%Couleur et forme :SoildMasse moléculaire :288.75(R)-(-)-Ibuprofen
CAS :<p>(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.</p>Formule :C13H18O2Degré de pureté :99.86%Couleur et forme :SolidMasse moléculaire :206.28NF-κΒ activator 1
CAS :<p>NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.</p>Formule :C16H11FN2O2SDegré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :314.33Coronalolic acid
CAS :<p>Coronalolic acid is a natural product extracted from the Gardenia sootepenesis Hutch. It inhibits TNF-α-induced NF-κB activity and NO production.</p>Formule :C30H46O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :470.68PROTAC STING degrader-3
<p>PROTACSTING degrader-3 (Compound ST9) is a STINGPROTAC-type degrader with a DC50 of 0.62 μM. It induces STING degradation via the ubiquitin-proteasome pathway. This compound exerts anti-inflammatory effects by inhibiting the STING/TBK1/NF-κB signaling. Additionally, it offers renal protection and can be used in research on acute kidney injury.</p>Couleur et forme :Odour SolidLemnalol
CAS :<p>Lemnalol, from Lemnalia cervicorni, has anti-inflammatory and analgesic properties.</p>Formule :C15H24ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :220.35Mesalamine impurity P
CAS :<p>Mesalamine impurity P, a 5-Aminosalicylic acid derivative, is a PPARγ agonist, inhibiting PAK1 and NF-κB.</p>Formule :C13H11NO6SCouleur et forme :SolidMasse moléculaire :309.30Anti-inflammatory agent 51
CAS :<p>Anti-inflammatory agent 51 amide/sulfonamide anti-inflammatory and anti-tumor activity inhibition of NF-κB activation acute lung injury and ulcerative colitis.</p>Formule :C22H22N6O6SDegré de pureté :99.46%Couleur et forme :SoildMasse moléculaire :498.51PROTAC IRAK4 degrader-12
CAS :<p>PROTAC IRAK4 degrader-12, a Cereblon ligand-based PROTAC, induces a maximum degradation of IRAK4 in K562 cells at 108.46% with an IC50 value of 4.87 nM. (Structure Note: Pink, IRAK4 Inhibitor; Blue, E3; Black, linker.)</p>Formule :C46H50ClF2N11O6Couleur et forme :SolidMasse moléculaire :926.41RIPK1-IN-27
<p>RIPK1-IN-27 (compound 19) is an inhibitor of RIPK1.</p>Formule :C27H28N4O3Couleur et forme :SolidMasse moléculaire :456.54PROTAC IRAK4 ligand-4
CAS :<p>PROTAC IRAK4 ligand-4, a Ligand for Target Protein for PROTAC (Ligand for Target Protein for PROTAC), exhibits anti-tumor activity and is utilized in synthesizing PROTAC IRAK4 degrader-12. This compound serves as a targeted ligand with specific applications in the development of cancer therapeutics.</p>Formule :C24H26F2N6O3Couleur et forme :SolidMasse moléculaire :484.5Antidesmone
CAS :<p>Antidesmone from Ajuga decumbens inhibits acute lung injury by modulating MAPK and NF-κB.</p>Formule :C19H29NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.44R-HP210
<p>R-HP210 blocks LPS-triggered IL-1β, IL-6, COX-2 gene transcription and has a 3.80 μM IC50 for NF-κB inhibition without activating GCs.</p>Formule :C22H19N3O2S2Couleur et forme :SolidMasse moléculaire :421.54Mitogen-activated protein kinase 1
CAS :<p>Mitogen-activated protein kinase 1 (MAPK1) activates the p38/NF-κB pathway and regulates cellular processes in sepsis-associated diseases.</p>Degré de pureté :98%Couleur et forme :SolidLY2409881
CAS :<p>LY2409881 is a selective IκB kinase β ( IKK2 ) inhibitor with an IC 50 of 30 nM.</p>Formule :C24H29ClN6OSCouleur et forme :SolidMasse moléculaire :485.05Edecesertib
CAS :<p>Edecesertib (GS 5718) is an IRAK-4 inhibitor with anti-inflammatory activity for the study of rheumatoid arthritis.</p>Formule :C22H22FN7O2Degré de pureté :98.84% - 99.94%Couleur et forme :SolidMasse moléculaire :435.45IRAK4-IN-8
CAS :<p>IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and inflammation.</p>Formule :C23H23F2N7O2SDegré de pureté :99.33%Couleur et forme :SolidMasse moléculaire :499.54IRAK4-IN-10
CAS :<p>IRAK4-IN-10, a potent IRAK4 blocker with IC50 of 1.5 nM, may treat inflammation, autoimmunity, and cancer.</p>Formule :C22H24N8Degré de pureté :98.55%Couleur et forme :SolidMasse moléculaire :400.48ML 120B dihydrochloride
CAS :<p>MLN120B dihydrochloride: oral IKKβ inhibitor with 60 nM IC50, suppresses myeloma growth, used in arthritis research.</p>Formule :C19H17Cl3N4O2Couleur et forme :SolidMasse moléculaire :439.72IRAK inhibitor 2
CAS :<p>IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.</p>Formule :C17H14N4O2Degré de pureté :97.90% - 99.58%Couleur et forme :SolidMasse moléculaire :306.32Hesperidin methylchalcone
CAS :<p>Hesperidin methylchalcone, from Citrus, is a potent antioxidant that inhibits NF-κB to alleviate gout arthritis in mice.</p>Formule :C29H36O15Degré de pureté :99.53%Couleur et forme :Yellow PowderMasse moléculaire :624.59DTP3
CAS :<p>DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.</p>Formule :C26H35N7O5Couleur et forme :SolidMasse moléculaire :525.6BIZ 114
CAS :<p>BIZ 114 potently inhibits the TNF-α activated NF-κΒ pathway. BIZ 114 has the potential to prevent and/or treat ophthalmic disorders.</p>Formule :C24H40O3Couleur et forme :SolidMasse moléculaire :376.57RS 09
CAS :<p>TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.</p>Formule :C31H49N9O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :691.78TOMATIDINE HYDROCHLORIDE
CAS :<p>Tomatidine hydrochloride (Tomatidine HCl) is a steriodal alkaloid structurally similar to Cyclopamine but does not inhibit hedgehog pathway.</p>Formule :C27H46ClNO2Degré de pureté :99.75% - ≥95%Couleur et forme :SolidMasse moléculaire :452.11Convallatoxin
CAS :<p>Convallatoxin is a natural product.</p>Formule :C29H42O10Degré de pureté :99.27% - 99.53%Couleur et forme :Prisms From Methanol + Ether SolidMasse moléculaire :550.64QNZ
CAS :<p>QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.</p>Formule :C22H20N4ODegré de pureté :99.17% - 99.18%Couleur et forme :White SolidMasse moléculaire :356.42BEC hydrochloride
CAS :<p>BEC hydrochloride (BEC HCl) is a competitive arginase inhibitor, which bind slowly. Ki of BEC HCl is 0.31 μM (pH7.5) for Arginase II.</p>Formule :C5H12BNO4S·ClHDegré de pureté :98.65% - 99.28%Couleur et forme :SolidMasse moléculaire :229.49Cornuside
CAS :<p>Cornuside boosts immunity, reduces inflammation, protects heart and liver, and guards against brain injury by modulating stress responses.</p>Formule :C24H30O14Degré de pureté :99.86% - >99.99%Couleur et forme :SolidMasse moléculaire :542.49CAFESTOL
CAS :<p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>Formule :C20H28O3Degré de pureté :97.06% - 99.08%Couleur et forme :SolidMasse moléculaire :316.43Demethyleneberberine
CAS :<p>Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria either</p>Formule :C19H18NO4Degré de pureté :98.08% - 99.18%Couleur et forme :SolidMasse moléculaire :324.35Morusin
CAS :<p>Morusin shows anti-tumor, antioxidant, and anti-inflammatory properties by inhibiting STAT3, NFκB, and inducing apoptosis.</p>Formule :C25H24O6Degré de pureté :98.68% - 99.8%Couleur et forme :SolidMasse moléculaire :420.45EUK-134
CAS :<p>EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.</p>Formule :C18H18ClMnN2O4Degré de pureté :98.39%Couleur et forme :SolidMasse moléculaire :416.74Flavanomarein
CAS :<p>Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.</p>Formule :C21H22O11Degré de pureté :98.63% - 99.54%Couleur et forme :SolidMasse moléculaire :450.39γ-Tocotrienol
CAS :<p>γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E.</p>Formule :C28H42O2Degré de pureté :97.27% - 98.13%Couleur et forme :SolidMasse moléculaire :410.63Quinoclamine
CAS :<p>Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.</p>Formule :C10H6ClNO2Degré de pureté :99.13% - 99.28%Couleur et forme :Orange PowderMasse moléculaire :207.613'-Sialyllactose
CAS :<p>3'-Sialyllactose (3'-SL), a prebiotic, supports immunity, reduces inflammation and arthritis, and is low-toxicity for research.</p>Formule :C23H39NO19Couleur et forme :SolidMasse moléculaire :633.55OPHIOPOGONIN D
CAS :<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Formule :C44H70O16Degré de pureté :99.46% - ≥95%Couleur et forme :SolidMasse moléculaire :855.02Rocaglamide
CAS :<p>Rocaglamide (Roc-A) from Aglaia treats coughs, injuries, asthma, skin issues, and inhibits NF-κB in T-cells.</p>Formule :C29H31NO7Degré de pureté :95.32% - 99.67%Couleur et forme :SolidMasse moléculaire :505.56BI-69A11
CAS :<p>BI-69A11 is a dual AKT/NFkB inhibitor, increasing colon cancer cell sensitivity to mda-7/IL-24.</p>Formule :C25H16ClN3O2Degré de pureté :96.97%Couleur et forme :SolidMasse moléculaire :425.87Bortezomib
CAS :<p>Bortezomib (LDP 341) is a 20S proteasome inhibitor (Ki=0.6 nM) that is reversible and selective.</p>Formule :C19H25BN4O4Degré de pureté :97.79% - >99.99%Couleur et forme :Yellow SolidMasse moléculaire :384.24Curculigoside
CAS :<p>1.</p>Formule :C22H26O11Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :466.44GSK481
CAS :<p>GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.</p>Formule :C21H19N3O4Degré de pureté :98.97%Couleur et forme :SolidMasse moléculaire :377.39IMM-H007
CAS :<p>IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression</p>Formule :C22H23N5O8Degré de pureté :97.73%Couleur et forme :SolidMasse moléculaire :485.45Sulfuretin
CAS :<p>Sulfuretin protects HepG2 cells from oxidative damage by scavenging ROS and activating HO-1 via Nrf2/ARE and JNK/ERK pathways.</p>Formule :C15H10O5Degré de pureté :98.91% - 99.86%Couleur et forme :SolidMasse moléculaire :270.24Benzoyloxypaeoniflorin
CAS :<p>Benzoyloxypaeoniflorin, a natural compound, enhances blood flow by inhibiting platelet aggregation and coagulation.</p>Formule :C30H32O13Degré de pureté :98.52% - 99.96%Couleur et forme :SolidMasse moléculaire :600.57Ethacrynic acid
CAS :<p>Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。</p>Formule :C13H12Cl2O4Degré de pureté :98.61% - 99.85%Couleur et forme :Crystals Physical Description White Solid (Ntp 1992)Masse moléculaire :303.14Flaconitine
CAS :<p>Flaconitine (Acetylaconitine) is an NF-κB inhibitor and an alkaloid.</p>Formule :C36H49NO12Degré de pureté :98% - 99.84%Couleur et forme :SolidMasse moléculaire :687.77Vanillic Acid
CAS :<p>Vanillic Acid (Acide vanillique) is used as a condiment in food, which used in wine. It is an intermediate in the production of vanillin from ferulic acid.</p>Formule :C8H8O4Degré de pureté :99.82%Couleur et forme :White Odourless Crystals Or PowderMasse moléculaire :168.152-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC
CAS :<p>2-AMINO-5-PHENYL-THIOPHENE-3-CARBOXYLIC is Inhibitior of IKKβ.</p>Formule :C11H10N2OSDegré de pureté :99.48%Couleur et forme :SolidMasse moléculaire :218.27BOT-64
CAS :<p>BOT-64 is an IKK-2 inhibitor which targets the Ser177 and/or Ser181 residues in the kinase's activation loop domain.BOT-64 is a cell-permeable benzoxathiole</p>Formule :C15H15NO2SDegré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :273.3518α-Glycyrrhetinic acid
CAS :<p>18α-Glycyrrhetinic acid (Enoxolone) is a pentacyclic triterpenoid derivative of the beta-amyrin type obtained from the hydrolysis of glycyrrhizic acid.</p>Formule :C30H46O4Degré de pureté :98.54% - 99.68%Couleur et forme :SolidMasse moléculaire :470.68(E/Z)-IT-603
CAS :<p>(E/Z)-IT-603 is a cell-permeable c-Rel inhibitor. IT-603 directly and reversibly binds to c-Rel to change its conformation and blocks its DNA binding activity.</p>Formule :C11H9BrN2O3SDegré de pureté :99.35%Couleur et forme :SolidMasse moléculaire :329.17Ginsenoside Rk3
CAS :<p>Ginsenosides Rk3 & Rh4 may treat inflammation and ischemic heart disease.</p>Formule :C36H60O8Degré de pureté :99.33% - 99.88%Couleur et forme :SolidMasse moléculaire :620.86Asperulosidic acid
CAS :<p>Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines.</p>Formule :C18H24O12Degré de pureté :99.47%Couleur et forme :SolidMasse moléculaire :432.38BX795
CAS :<p>BX795 selectively inhibits PDK1 (IC50: 6 nM), 140x over PKA, 1600x over PKC, 100x over GSK3β in cell-free assays.</p>Formule :C23H26IN7O2SDegré de pureté :98% - 99.57%Couleur et forme :SolidMasse moléculaire :591.47Galloylpaeoniflorin
CAS :<p>Galloylpaeoniflorin (6'-O-Galloyl paeoniflorin) may be developed as a cytoprotector against ROS-mediated oxidative stress.</p>Formule :C30H32O15Degré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :632.57AS-2444697
CAS :<p>AS-2444697, an IRAK-4 inhibitor (C50=21 nM), offers renal protection via anti-inflammatory effects on human and rat IRAK-4.</p>Formule :C19H21ClN6O4Degré de pureté :97.17%Couleur et forme :SolidMasse moléculaire :432.86AZD3264
CAS :<p>AZD3264 is a new type IKK2 inhibitor.</p>Formule :C21H23N5O4SDegré de pureté :98.98% - 99.17%Couleur et forme :SolidMasse moléculaire :441.5IRAK4-IN-7
CAS :<p>IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.</p>Formule :C21H19N7O3Degré de pureté :99.5%Couleur et forme :SolidMasse moléculaire :417.42SC-514
CAS :<p>SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.</p>Formule :C9H8N2OS2Degré de pureté :99.88% - >99.99%Couleur et forme :SolidMasse moléculaire :224.3Cyclo(his-pro)
CAS :<p>Cyclo(his-pro) is a cyclic dipeptide that shields against oxidative damage by activating Nrf2.</p>Formule :C11H14N4O2Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :234.25Astaxanthin
CAS :<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Formule :C40H52O4Degré de pureté :95.1% - 99.79%Couleur et forme :Needles From Acetone/Light Petroleum SolidMasse moléculaire :596.847,4'-Dihydroxyflavone
CAS :<p>7,4'-Dihydroxyflavone (4',7-Dihydroxyflavone) can induce transcription of nodulation (nod) genes in Rhizobium meliloti.</p>Formule :C15H10O4Degré de pureté :99.39% - 99.6%Couleur et forme :SolidMasse moléculaire :254.24Rucaparib
CAS :<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Formule :C19H18FN3ODegré de pureté :98.24% - 99.80%Couleur et forme :SolidMasse moléculaire :323.36Avicularin
CAS :<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Formule :C20H18O11Degré de pureté :97.02% - 99.94%Couleur et forme :White PowderMasse moléculaire :434.35Berbamine
CAS :<p>Berbamine is a natural product extracted from Phellodendron amurense.</p>Formule :C37H40N2O6Degré de pureté :98.92% - 99.67%Couleur et forme :White Crystal PowderMasse moléculaire :608.72Tizoxanide
CAS :<p>Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.</p>Formule :C10H7N3O4SDegré de pureté :98.89% - 99.28%Couleur et forme :SolidMasse moléculaire :265.25Micheliolide
CAS :<p>Micheliolide(MCL) is a sesquiterpene lactone which inhibits various inflammatory response.</p>Formule :C15H20O3Degré de pureté :98% - 99.37%Couleur et forme :SolidMasse moléculaire :248.32Ginsenoside Rb3
CAS :<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Formule :C53H90O22Degré de pureté :98% - 99.98%Couleur et forme :SolidMasse moléculaire :1079.27Chelidonic acid
CAS :<p>Chelidonic acid, in Chelidonium majus, acts as an analgesic, antimicrobial, CNS sedative, and has anti-inflammatory properties.</p>Formule :C7H4O6Degré de pureté :99.03%Couleur et forme :SolidMasse moléculaire :184.1Ac2-26 acetate
<p>Ac2-26 acetate is an active N-terminal peptide of annexin A1(AnxA1).</p>Formule :C141H210N32O44SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :3089.43Rhoifolin
CAS :<p>Rhoifolin (Apigenin 7-O-neohesperidoside) is extracted from Turpinia arguya Seem dried leaves.</p>Formule :C27H30O14Degré de pureté :98.11% - 98.58%Couleur et forme :SolidMasse moléculaire :578.52Isoquercetin
CAS :<p>1.</p>Formule :C21H20O12Degré de pureté :98.08% - 99.76%Couleur et forme :SolidMasse moléculaire :464.38Muscone
CAS :<p>Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.</p>Formule :C16H30ODegré de pureté :98.97% - ≥98%Couleur et forme :Colourless Liquid LiquidMasse moléculaire :238.41Eclitasertib
CAS :<p>Eclitasertib is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1, IC50 of <1 µΜ).</p>Formule :C19H18N6O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :378.38Sodium Aescinate
CAS :<p>Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.</p>Formule :C54H83NaO23Degré de pureté :95.17%Couleur et forme :SolidMasse moléculaire :1123.21Ginsenoside Rd
CAS :<p>Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.</p>Formule :C48H82O18Degré de pureté :99.13% - 99.92%Couleur et forme :SolidMasse moléculaire :947.15WITHAFERIN A
CAS :<p>WITHAFERIN A is a novel class of NFkappaB inhibitors, which hold promise as novel anti-inflammatory agents for treatment of various inflammatory disorders and/</p>Formule :C28H38O6Degré de pureté :97.41% - 99.99%Couleur et forme :SolidMasse moléculaire :470.6Dehydroevodiamine
CAS :<p>Dehydroevodiamine (DHED), a constituent of Evodia rutaecarpa, has various biological effects such as hypotensive, negative chronotropic, ion channel depressant</p>Formule :C19H15N3ODegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :301.34Diethylmaleate
CAS :<p>Diethylmaleate (Maleic acid, diethyl ester) is the diethyl ester of maleic acid and a glutathione-depleting compound that inhibits NF-kB.</p>Formule :C8H12O4Degré de pureté :98%Couleur et forme :Colourless LiquidMasse moléculaire :172.18Sinomenine
CAS :<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Formule :C19H23NO4Degré de pureté :99.02% - 99.73%Couleur et forme :White PowderMasse moléculaire :329.392-Hydroxychalcone
CAS :<p>2-Hydroxychalcone (2-(2-Hydroxybenzal)Acetophenone) can be used as antiparasitic hit compounds when Methoxylated. It inhibits invasion of breast cancer cells.</p>Formule :C15H12O2Degré de pureté :99.6%Couleur et forme :SolidMasse moléculaire :224.252,5-Dihydroxyacetophenone
CAS :<p>2,5-Dihydroxyacetophenone has anti-anxiety, neuroprotective, anti-inflammatory properties, and modulates cell signaling and melanogenesis.</p>Formule :C8H8O3Degré de pureté :99.75%Couleur et forme :Yellow PowderMasse moléculaire :152.15Dauricine
CAS :<p>1.</p>Formule :C38H44N2O6Degré de pureté :99.24% - 99.75%Couleur et forme :White PowderMasse moléculaire :624.77Dendrophenol
CAS :<p>Dendrophenol (Moscatilin) is a natural product isolated from the stem of Dendrobium loddigesii Rolfe, act as a NF-κB inhibitor. Antineoplastic activity.</p>Formule :C17H20O5Degré de pureté :98.2% - 99.36%Couleur et forme :SolidMasse moléculaire :304.34GSK8612
CAS :<p>GSK8612 is a highly selective and potent inhibitor of Tank-binding Kinase-1 (TBK1, pIC50: 6.8) .</p>Formule :C17H17BrF3N7O2SDegré de pureté :99.46% - 99.8%Couleur et forme :SolidMasse moléculaire :520.33IRAK inhibitor 6
CAS :<p>IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).</p>Formule :C20H20N4O3SDegré de pureté :99.44%Couleur et forme :SolidMasse moléculaire :396.46Phellodendrine
CAS :<p>Phellodendrine may treat nephritis by blocking macrophage and T cell activity in glomeruli.</p>Formule :C20H24NO4Degré de pureté :98.7% - 99.94%Couleur et forme :SolidMasse moléculaire :342.41yangonin
CAS :<p>Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.</p>Formule :C15H14O4Degré de pureté :98.82% - 99.55%Couleur et forme :Pale Yellow PowderMasse moléculaire :258.27Iron sucrose
CAS :<p>Iron sucrose (Sucroferric oxyhydroxide) is treatment of iron deficiency anemia.</p>Formule :C18H24Fe2O24Degré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :736.1Isovitexin
CAS :<p>1.</p>Formule :C21H20O10Degré de pureté :99.79% - 99.97%Couleur et forme :SolidMasse moléculaire :432.38Neochlorogenic acid
CAS :<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Formule :C16H18O9Degré de pureté :99.12% - 99.54%Couleur et forme :White PowderMasse moléculaire :354.31Denosumab
CAS :<p>Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand</p>Formule :C6404H9912N1724O2004S50Degré de pureté :95.9% (SDS-PAGE); 98.4% (SEC-HPLC) - 99.90%Couleur et forme :LiquidMasse moléculaire :144.71 kDaTriacetylresveratrol
CAS :<p>Triacetylresveratrol (Acetyl-trans-resveratrol) has anti-cancer activity, it inhibits the phosphorylation of STAT3 and NFκB in pancreatic cancer cells.</p>Formule :C20H18O6Degré de pureté :99.81%Couleur et forme :Off White PowderMasse moléculaire :354.35IMD-0354
CAS :<p>IMD-0354 (IKK2 Inhibitor V) is an IKKβ inhibitor and inhibits IκBα phosphorylation in NF-κB pathway.</p>Formule :C15H8ClF6NO2Degré de pureté :99.65% - 99.98%Couleur et forme :SolidMasse moléculaire :383.67Necrostatin-34
CAS :<p>Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) is a RIPK1 kinase inhibitor, stabilizing RIPK1 kinase in an inactive conformation by occupying a</p>Formule :C18H16N4O2S2Degré de pureté :98.66% - 98.8%Couleur et forme :SolidMasse moléculaire :384.48
