Étalons pharmaceutiques

<p>Applications 3-Nitrophenylhydrazine Hydrochloride acts as a reagent in the preparation of isosteviol-fused pyrazolines and pyrazoles as potential anticancer agents, preparation of pyrazolobenzothiazines as inhibitors of hepatitis C virus replication.<br>References Zhu, S., et al.: Eur. J. Med. Chem., 65, 70 (2013); Barreca, M. L., et al.: J. Med. Chem., 56, 2270 (2013);<br></p>

<p>Stability Hygroscopic<br>Applications 6-Amidino-2-naphthol Methanesulfonate is a useful N-terminal derivatization reagent for improving peptide fragmentation.<br>References Miyashita, M., et al.: Rapid Commun. Mass Spectrom., 25, 1130 (2011)<br></p>

<p>Applications Testosterone-16,16,17-d3 17-Phenylpropionate, is the labeled analogue of Testosterone 17-Phenylpropionate (T155150), a Testosterone ester being misused by athletes in an attempt to improve sports performance. It can also be used as a therapy in glucocorticoid-treated patients to increase the circulating testosterone concentration.<br>References Shackleton, C. H. L., et al.: Steroids, 62 (7), 523 (1997); Reid, I. R., et al.: Archives Internal Med., 156 (11), 1173 (1996);<br></p>

<p>Applications (+)-trans-Jasmonic Acid is an enantiomer of trans-Jasmonic Acid (J210520) a major constituent of essential oil of Jasmine. Used by the fragrance industry. This product is a clear, colorless to very light yellow oil that adheres to the surface of the vial.<br>References Hamberg, M., et al.: Biochim. Biophys Acta, 1165, 1 (1992), Tizio, R., et al.: Biocell, 20, 1 (1996), Farmer, E., et al.: Science, 276, 912 (1997),<br></p>

<p>Applications Norcamphor is a building block that is used in organic synthesis. Norcamphor has been used as a reactant in the synthesis of cardo-polymers with high gas permeabilities.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Carta, M., et. al.: Polymer Chem., 5, 5255 (2014)<br></p>

<p>Stability Unstable in Solution<br>Applications β-Ketoglutaric Acid is used in the synthesis of benzodiazepine derivatives. Also used in the synthesis of orally available hepatitis C virus polymerase inhibitors.<br>References Jung, D. et al.: Synth. Comm., 29, 1941 (1999); Li, H. et al.: J. Med. Chem., 52, 1255 (2009);<br></p>

<p>Applications 1,3-Diethyl-2-thiourea (cas# 105-55-5) is a useful research chemical.<br></p>

<p>Applications B-1-Naphthalenyl-boronic Acid is a useful synthetic intermediate. It is a reagent used to synthesize potassium aryltrifluoroborates which is a convenient precursor of arylboron difluoride lewis acids. It can also be used to prepare high yields of biaryls via Suzuki coupling.<br>References Vedejs, E., et al.: J. Org. Chem., 60, 3020 (1995); Larhed, M., et al.: Tetrahedron Lett., 37, 8219 (1996); Singh, R., et al.: 7, 1829 (2005)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma.<br>References D’Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994); Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999); Parma, T., et al.: Nat. Med., 5, 582 (1999); Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)<br></p>

<p>Applications 5,8-Dibromo-2-naphthalenecarboxylic Acid is bromo substituted naphthalene carboxylic acid which is a useful research reagent.<br>References Wang, X., et al.: Ultrasound Sonochemistry, 47,57 (2018)<br></p>

<p>Applications β-Cyclogeraniol (cas# 472-20-8) is a compound useful in organic synthesis.<br></p>

<p>Applications N-(2-Chloroethyl)-N'-(4-pyridinyl)urea (cas# 62491-96-7) is a useful research chemical.<br></p>

<p>Applications α-Naphthyl-d7 Glycidyl Ether is an intermediate in the synthesis of rac-Propranolol-d7 (P831803) which is the labeled analogue of Propranolol (P831800), a β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).<br>References Bond, et al.: Nature, 213, 721 (1967), Hansteen, V., et al.: Br. Med. J., 284, 155 (1982), Diamond, S., et al.: J. Clin. Pharmacol., 28, 193 (1988),<br></p>

<p>Applications (2-​Deoxy-​D-​erythro-​pentofuranosyl)​-urea is used as a reactant in the preparation of 2'-deoxyribosylurea by thymidine oxidation.<br>References Dubey, I., et al.: Nucleos. Nucleot. Nucl., 20, 1463 (2001)<br></p>

<p>Applications Anthracene-d10 is an isotope labelled analogue of Anthracene (A678400), an polycyclic aromatic hydrocarbon found readily as an component in coal tar. Anthracene is also used in the preparation of various dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>4'-Chloroacetophenone is a chemical substance that is used in the synthesis of other substances. It has been shown to be an effective tool for cell-specific reactions, such as methyl ketones and benzaldehyde. 4'-Chloroacetophenone reacts with hydrochloric acid and palladium complexes to produce electron reduction, which leads to the activation of methyl ketones. This reaction provides a method for synthesizing molecules with a carbonyl group. The isolated yield of this reaction is dependent on the reaction solution temperature and concentration. The mechanism of this reaction appears to be Suzuki coupling reaction.</p>

<p>Please enquire for more information about N-Cyano-N',S-dimethylisothiourea including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-Nitrophenyl hexanoate is an acyl phosphate monoclonal antibody (aMAb) that binds to the enzyme hydroxylase, which converts 4-nitrophenol to p-nitrophenol. This aMAb has been shown to inhibit the activity of this enzyme and its conversion of 4-nitrophenol to p-nitrophenol, leading to its use in biochemical studies as a model for monooxygenase enzymes. The reaction mechanism for this aMAb is believed to be that it reacts with the acyl chain of hydroxylase and hinders the active site from binding 4-nitrophenol. 4-Nitrophenyl hexanoate also has a cationic surfactant that can bind or react with proteins or nucleic acids by electrostatic interactions or hydrogen bonding. It is also able to form polymers with other monoclonal antibodies and has been used in protein purification processes</p>

<p>Tetramethylurea is a versatile compound that has various applications in different fields. It is commonly used as a monophosphate donor in biochemical reactions and as a reagent for the synthesis of L-sorbose and histidine. In addition, tetramethylurea is employed in the production of herbicides, as well as in the synthesis of zirconium oxide nanoparticles.</p>

<p>9-cisRetinol is a form of vitamin A that plays an important role in the synthesis of lipids and proteins. It has been shown to inhibit acid formation in the liver and to stimulate growth in some types of cancer cells. 9-cisRetinol is converted to all-trans retinoic acid, which is a nuclear hormone receptor that regulates gene expression. It also has been shown to be effective in clinical studies for the treatment of congenital amaurosis and cancer. 9-cisRetinol can inhibit phospholipase A2, which prevents the release of arachidonic acid from membrane phospholipids, as well as inhibit prostaglandin synthesis. The optimum pH for 9-cisRetinol activity is between 7 and 8.</p>

<p>Salbutamol sulphate impurity B is a substance that is an impurity in salbutamol sulfate. It is a white crystalline powder and is soluble in organic solvents. Salbutamol sulfate impurity B can be detected by liquid chromatography, which separates the substances based on their solubility in different phases. The substances are detected at a specific wavelength, and it is possible to identify peaks of the substances on the chromatogram synchronously. Salbutamol sulfate impurity B can be found as a part of other medicines or substances by using this detection method.</p>

<p>L-proline analogue</p>

<p>4'-Hydroxyatomoxetine is a metabolite of atomoxetine, which is a drug that is used to treat attention deficit hyperactivity disorder and narcolepsy. 4'-Hydroxyatomoxetine has been shown to have pharmacological properties similar to those of atomoxetine. However, it does not bind to the κ-opioid receptors, unlike its parent drug. The analytical method for this metabolite has been developed using liquid chromatography with tandem mass spectrometry. The major limitation with the analytical method is that it can be affected by matrix effects and hepatic impairment. This metabolite is glucuronidated and then conjugated with trifluoroacetic acid (TFA) before excretion in urine or bile. It also binds to kappa-opioid receptors, but at a lower affinity than its parent compound.</p>

<p>All-trans-retinol is a form of vitamin A that is found in many animal tissues and some plant oils. It acts as a hormone, binding to the retinoic acid receptors (RARs) in the nucleus and activating gene transcription. All-trans-retinol has been shown to be effective against hyperproliferative diseases such as cancer, both by inducing apoptosis and by inhibiting cell growth. All-trans-retinol may also have therapeutic potential for other diseases, such as intestinal cancers and prostatic hypertrophy. This compound has been shown to induce messenger RNA (mRNA) production in cells that express RARs.</p>

<p>Please enquire for more information about 2N-Boc-2',2''-triaminotriethylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>24(S)-Hydroxycholesterol is a cholesterol metabolite that is synthesized by the liver and can be found in human serum. It has been shown to be an important inducer of transcriptional regulation, as it regulates the expression of genes involved in lipid metabolism and inflammatory response. 24(S)-Hydoxycholesterol is also an activator of the peroxisome proliferator-activated receptor (PPAR) and may cause hepatic steatosis. This molecule has potent activity in inducing polymerase chain reaction (PCR) and protein synthesis in neuronal cells, leading to neuronal death. The molecule also induces apoptosis by caspase-independent cell death, which is mediated by mitochondrial membrane potential. 24(S)-Hydoxycholesterol may serve as a biomarker for nonsteroidal anti-inflammatory drugs (NSAIDs), with low potency against these drugs.br&gt;</p>

<p>2,4,4’-Trichlorobiphenyl is a polychlorinated biphenyl congener. It has been shown to have an adverse effect on the central nervous system, causing neurotoxicity. 2,4,4’-Trichlorobiphenyl has been used as a model system for the study of the effects of environmental toxins on mitochondrial membrane potential and lipid peroxidation. 2,4,4’-Trichlorobiphenyl binds to fatty acids in mitochondria and inhibits fatty acid β-oxidation. The inhibition of fatty acid oxidation leads to increased levels of protocatechuic acid in the serum and liver tissue. 2,4,4’-Trichlorobiphenyl has also been found to be toxic to aquatic organisms such as fish and shrimp at low concentrations.</p>

<p>Zeta-carotene is a carotenoid pigment found in plants. It is a precursor to vitamin A and can be converted by the body into retinol, which can then be used in the eye. Zeta-carotene has been shown to inhibit the growth of cancer cells through transcriptional regulation of genes involved in lipid metabolism and cell proliferation. This carotenoid also has antioxidant properties that may help protect against cardiovascular diseases. In addition, zeta-carotene has been shown to have a positive effect on plant physiology because it is an important intermediate for photosynthesis.</p>

<p>Please enquire for more information about Amoxicillin dimer tri-sodium salt (penicilloic acid form) - mixture of diastereomers including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>21-Chloro-9-fluoro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-propionate is an ester of ketoconazole and the propionic acid. It is used as a pharmaceutical formulation and has been shown to be stable in an HPLC method. This compound also has an optical isomer that was validated by a stability test. This product has been shown to have antiinflammatory properties and may be used as a topical treatment for skin disorders such as clobetasol propionate.</p>

<p>Please enquire for more information about Cholesterol trans-Cinnamate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 17a-Methyl-4-[(phenylthio)methyl]testosterone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Cyclohexyl-4,6-dinitrophenol is a chemical that inhibits the synthesis of viral DNA. It has been shown to have minimal toxicity in animal models and may be used for the treatment of metabolic disorders, such as hepatic steatosis or hepatitis. 2-Cyclohexyl-4,6-dinitrophenol has also been shown to inhibit the toll-like receptor (TLR) pathway and induce an antiviral state in vitro. In addition, it was found to have an effect on mitochondrial membrane potential, which may explain its antiviral activity. 2-Cyclohexyl-4,6-dinitrophenol has also been shown to inhibit viral replication in cells infected with HIV and other viruses such as Hepatitis C virus.</p>

<p>Please enquire for more information about 5'-Amino-5'-deoxy-2',3'-O-(1-methylethylidene)-adenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Roxithromycin EP Impurity C is a byproduct of the synthesis of erythromycin. It has been shown to have anti-inflammatory activity in liver cells, and has been used as a model for studying the mechanism of action of erythromycin. The reaction solution contains inorganic acid and nitrogen atoms. Roxithromycin EP Impurity C reacts with erythromycin to form an intermediate that then undergoes a series of reactions, including hydroxylation, oxidation, and decarboxylation. The purified product is made up of carbonyl groups and transcriptional regulation. This impurity can also be found in cell nuclei.</p>

<p>3-Cyanopropionic acid methyl ester is a compound that belongs to the class of aliphatic carboxylic acids. It is an intermediate in the production of adiponitrile and acrylonitrile. This compound is used as a feedstock for the manufacture of vinylene, which can be used to produce c1-6 alkyl. 3-Cyanopropionic acid methyl ester can be produced from propylene and hydrogen cyanide in a high salt, activated reaction system. It has been shown that this compound may have metabolic disorders due to its ability to inhibit fatty acid oxidation and increase viscosity. 3-Cyanopropionic acid methyl ester is a colorless liquid at room temperature with a boiling point of 154°C and a molecular weight of 98.14 g/mol.</p>

<p>(S)-3',5'-Bis(trifluoromethyl)-1-phenethanol is a choline derivative that is used in the treatment of liver cancer. It has been shown to increase the permeability of cell membranes and to suppress the growth of tumor cells by inhibiting protein synthesis. (S)-3',5'-Bis(trifluoromethyl)-1-phenethanol can be used as a surfactant and a hydrophobic solvent for optimization of reaction parameters. This chemical also has been shown to be active against Gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis, but not against Gram-negative bacteria such as Escherichia coli or Pseudomonas aeruginosa. The mechanism of this effect is mediated by chloride ions that act as bioreductive agents on cellular membranes, leading to increased permeability and cell death.</p>

<p>Please enquire for more information about (+)-(8,8-Dichlorocamphorylsulfonyl)oxaziridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Cholesterol Isobutyl Carbonate is a high melting organic solvent that has been used to prepare microcapsules. It can be used as a coating material for the preparation of inorganic particles, and it has been shown to have the ability to modify molecules by attaching functional groups. The diameter of cholesterol iso butyl carbonate particles is around 100 nm.</p>

<p>Please enquire for more information about 21-Hydroxy-pregna-1,4,16-triene-3,11,20-trione 21-acetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2-Bromo-3'-hydroxyacetophenone is a molecule that has been shown to be cytotoxic and effective in inhibiting the growth of cancer cells. 2-Bromo-3'-hydroxyacetophenone inhibits the production of kynurenine, an amino acid that is used in the production of proteins, by competitively binding to the enzyme IDO1. This binding prevents the conversion of tryptophan into kynurenine, leading to cell death. The cytotoxicity of 2-bromo-3'-hydroxyacetophenone was also confirmed by testing its ability to inhibit cellular interaction with human erythrocytes (blood cells) and by measuring its effects on crystallography efficiency.</p>

<p>Please enquire for more information about (17a)-13-Ethyl-3-methoxy-18,19-dinorpregna-3,5-dien-20-yn-17-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Atorvastatin acetonide is a statin drug that inhibits the synthesis of cholesterol by the liver. It is used to lower high cholesterol and triglycerides, as well as to reduce the risk of cardiovascular disease. Atorvastatin acetonide is a prodrug that is hydrolyzed in vivo to atorvastatin. Atorvastatin acetonide can be analyzed by HPLC with UV detection or by reversed-phase HPLC with fluorescence detection. The flow rate for this analysis is 0.5 mL/min and it takes about 20 min for analysis time. In order to monitor reaction progress, a calibration curve should be used for calibration and reaction monitoring. This product has linearity with recoveries of greater than 75%.</p>

<p>Testosterone 3-(O-carboxymethyl)oxime is an inactive prodrug of testosterone. It is a potent and selective inhibitor of angiotensin II that causes vasodilation by blocking the conversion of angiotensin I to angiotensin II. Testosterone 3-(O-carboxymethyl)oxime has been shown to be effective in lowering blood pressure in patients with congestive heart failure, although it may cause side effects such as dizziness, headache, and nausea. This drug can also be used to treat prostate cancer because it inhibits the production of testosterone and reduces serum levels of luteinizing hormone. Testosterone 3-(O-carboxymethyl)oxime can also be used for diagnostic purposes as a marker for polycystic ovary syndrome (PCOS).</p>

<p>Cholesterol butyl carbonate is a high-melting organic solvent. It has a particle diameter of 3.2 micrometers, an average particle size of 4.5 micrometers, and a section of 1.4. This product is used to form microcapsules with various coatings for the treatment of bacteria and fungi. It is also used as a molecule for the production of functional groups such as polyethylene glycol ethers or polyurethanes. The structural formula contains three functional groups: one ester group and two sterol groups (cholesterol). This product has enhanced properties due to its inorganic components that are added during processing.</p>

<p>Please enquire for more information about 1-Hexyl-3-(1-naphthoyl)pyrrole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Sevoflurane related compound A is a chemical that is used as a model for sevoflurane. It has been shown to inhibit the activity of proximal tubules and to increase blood pressure in rats and humans. The cytosolic reactive oxygen species (ROS) production has been shown to be involved in the mechanism of action. This compound was tested on animals, but was found not to be clinically useful due to its effects on urea nitrogen levels and other metabolic profiles. Sevoflurane related compound A has also been found to be reactive with herpes simplex virus.</p>

<p>Please enquire for more information about Budesonide Impurity 9 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 4,5-Dihydro-19-nortestosterone-17b-decanoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-YMDGTMSQVA-OH peptide, corresponding to 369-377 amino acids of enzyme tyrosinase. As a member of the tyrosinase family the corresponding enzyme catalyzes monopheol hydroxylation, dihydroxyindole and catechol dehydrogenation. It is a key enzyme in the conversion of tyrosine to melanin.</p>

<p>Please enquire for more information about Pravastatin 1,1,3,3-tetramethylbutylamine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Formoterol EP Impurity F (Mixture of Diastereomers) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>9,10-Diphenylanthracene is a fluorescent aromatic hydrocarbon that belongs to the class of carbonyl compounds. It has high values and maximal response with analytical methods such as fluorescence techniques and gel pores. 9,10-Diphenylanthracene can be used as a probe for the transfer mechanism of nucleic acids and proteins. 9,10-Diphenylanthracene is also used in analytical chemistry to determine the structure of dihydro derivatives of unsaturated alkyl chains. This compound's chemical properties make it an excellent fluorescent marker for use in gamma-aminobutyric acid (GABA) research.</p>

<p>Please enquire for more information about Diacetato[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]ruthenium(II) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about (-)-3-Methoxy butorphanol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Hydrocortisone is a corticosteroid that is used to treat inflammation, allergies and skin diseases. It is also used to treat adrenal gland disorders. Hydrocortisone Acetate Impurity G (HA) is a drug that has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis. HA was the first hydrocortisone impurity found in prednisolone tablets. This discovery led to the development of corticosteroids and their use in medicine for the treatment of inflammation and allergies.</p>

<p>Oxymorphone is a potent synthetic opioid analgesic with a short duration of action. It is a prodrug that has to be metabolized in the liver by cytochrome P450 enzymes for activation. The 6-hydroxy metabolite is more potent than oxymorphone itself and has been shown to have antinociceptive properties in mice. Oxymorphone is used in cancer patients as an oral dosage form, which may be administered with or without food. It has been shown that the albumin concentration influences the pharmacokinetics of oxymorphone and its metabolites. This drug also has immunomodulatory effects and can cause adverse events such as hypersensitivity reactions, nausea, vomiting, or constipation.</p>

<p>Please enquire for more information about Domperidone impurity E including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1-(3’,4’-Dimethoxyphenyl)-1-propanol is a naturally occurring chemical with the molecular formula C10H14O2. It has been found in the bark of Pinus pinaster and the rhizome of Piper auritum. This compound has been shown to have an antiinflammatory effect by inhibiting prostaglandin synthesis. It also inhibits nitrosation reactions and is being studied for its potential as a cancer chemopreventive agent. 1-(3’,4’-Dimethoxyphenyl)-1-propanol is an enantiomer of 2-(3',4'-dimethoxyphenyl)propane-1,3-diol.</p>

<p>Isoeugenol methyl ether is a plant-derived natural compound that is used in vitro as an antioxidant. It has been shown to inhibit the activity of enzymes such as hydroxylase, glucuronidase, and cytochrome P450. Isoeugenol methyl ether has also been shown to have anti-inflammatory properties and may be useful for treatment of colorectal adenocarcinoma. The mechanism by which isoeugenol methyl ether inhibits the enzyme activity is not clear but it may be due to its ability to bind reversibly with free enzyme form.</p>

<p>Please enquire for more information about 6-Bromo-1,2,3,4-tetrahydronaphthalen-2-ylamine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about rac-4'-Methyl ketoprofen including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dorzolamide hydrochloride related compound A including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Ilexsaponin B2 is a triterpenoid saponin, which is a bioactive compound extracted from plants in the Ilex genus, such as Ilex pubescens. These saponins are characterized by their glycosidic linkages to sapogenins, typically influencing membrane permeability and exhibiting diverse biological activities.</p>

<p>Delta6-Testosterone is a natural steroid hormone that belongs to the group of steroid drugs. It is a potent androgen, or male sex hormone, which stimulates the development and maintenance of male sexual characteristics, including the growth of prostate gland and seminal vesicles. The effects of Delta6-testosterone are mediated by binding to and activating the Androgen Receptor (AR). The effects may also be increased when Delta6-testosterone binds to AR in combination with other hormones such as estradiol.<br>Delta6-Testosterone is metabolized by the liver into testosterone through the cytochrome p450 enzyme system. This process begins with conversion of Delta6-testosterone into 6alpha-dihydrotestosterone (DHT) by 5a-reductase. DHT can then be converted into testosterone by 3beta-hydroxysteroid dehydrogenase/3alpha-hydroxysteroid dehydrogenase (3betaHSD) or 17beta hyd</p>

<p>Please enquire for more information about Delta9,11-Dehydro-17b-estradiol 17-valerate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about O-tert-Butyl-L-threonine 2-chlorotrityl resin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2'-Acetylacteoside is a naturally occurring phenylethanoid glycoside, which is derived from various plant sources. It exhibits antioxidant properties by scavenging reactive oxygen species and inhibiting oxidative stress. This mode of action supports cellular health by protecting cells from oxidative damage and maintaining redox balance.</p>

<p>1,2,3,4-Tetrahydronaphthalen-2-ylamine hydrochloride (THN) is a prodrug that is converted to the active form in the gastrointestinal tract by beta-lactamases. It inhibits bacterial growth and crosslinks bacterial cell walls. THN has been shown to be effective against colitis and ulcerative colitis in animals. It also has anticancer activity, which may be due to its ability to inhibit colon cancer cells from proliferating by interfering with protein synthesis. THN also inhibits the growth of colorectal cancer cells in a dose-dependent manner.</p>

<p>2-Naphthol is an organic compound with the chemical formula C10H7O. It is a derivative of naphthalene, and is produced by the condensation of two molecules of malonic acid in the presence of a reducing agent such as sodium borohydride. 2-Naphthol is used as a pesticide and as a chemical intermediate in the production of other chemicals. 2-Naphthol has been shown to be toxic to humans and animals; it may cause liver damage, kidney damage, and skin irritation. The acute oral LD50 for rats is 690 mg/kg body weight. 2-Naphthol binds to cell receptors that are involved in a variety of physiological processes including heme transport, phagocytosis, oxidative burst, chemotaxis, and respiratory burst. This binding inhibits these functions leading to cell death.</p>

<p>3-Nitropropionic acid (3NPA) is a mitochondrial toxin that causes neuronal death by inhibiting complex enzyme activities and inducing reactive oxygen species production. 3NPA also alters mitochondrial membrane potential and induces pro-apoptotic protein expression, leading to neuronal cell death. 3NPA has been shown to be effective in the treatment of experimental models of infectious diseases, such as rat sepsis and human HIV infection, by reducing the number of activated T cells and CD4+ T cells. 3NPA also exhibits anti-inflammatory properties by inhibiting the inflammatory responses of monocytes/macrophages and neutrophils.</p>

<p>Methionine sulfoxide is a methionine that has been oxidized to methionine sulfoxide. Methionine sulfoxides are produced through protein oxidation, which is the chemical process of reacting with oxygen in the air or other compounds to form an organic peroxide and superoxide radical. Methionine sulfoxides are found in proteins and are formed as a result of oxidative stress on cells and tissues. The rate constant for the conversion of methionine to methionine sulfoxide is 0.01983 min-1 at pH 7, 25°C. There are two methods of detection: chemiluminescence method and chromatographic analysis. In addition, methionine sulfoxides have natural antioxidant properties that can be used to treat diseases such as Alzheimer's disease and Parkinson's disease, as well as cancer treatments. Methionine sulfoxides have been shown to have a significant effect on wild-type strains of bacteria, reducing their growth rates</p>

<p>Please enquire for more information about Vitamin B12 e-Monocarboxylic Acid including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>2,2'-Dichlorodiethyl ether (2,2-DDE) is a cationic surfactant that is used in the production of fluorocarbons and other chemicals. It is also used in wastewater treatment as an oxidizing agent. 2,2'-DDE is toxic to humans, with a blood group toxicity profile similar to that of ethylene glycol and diethylene glycol. 2,2'-DDE can be found in the environment due to its use as a component in products and its presence in wastewaters. 2,2'-DDE has been shown to be reactive with hydrogen fluoride and oxidation catalyst, which may cause interactive effects when it is present at high concentrations. This chemical has been shown to induce cell death through histological analysis on cell cultures. Reaction mechanism for this chemical is not known.</p>

<p>Please enquire for more information about 5-Nitropyridin-3-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>b-Zeacarotene is a carotenoid molecule that is found in plants and animals. It has been shown to have an inhibitory effect on protein synthesis. b-Zeacarotene is a reactive compound that can react with other compounds to form new compounds, such as reaction products of the polyene type. In bacteria, transcriptional regulation of genes involved in carotenoid biosynthesis has been shown to be inhibited by b-zeacarotene.</p>

<p>5,8-Dihydro-1-naphthol is a chromatographic impurity of a β-blocker drug. It can be purified by alkali metal extraction, or by reaction with hydrochloric acid, followed by treatment with an adsorbent material such as silica gel, alumina, or activated carbon. Optimal conditions for the reaction are at a temperature of ˚C and a pressure of 100 kPa. The reaction time can vary from 10 minutes to 60 hours. Purification methods include chromatography and microscopy. 5,8-Dihydro-1-naphthol exhibits isomerization reactions in which it isomerizes to 1-(2'-hydroxyethyl)naphthalene and 1-(2'-methoxyethyl)naphthalene, which are both colorless compounds. These isomers may be separated using chromatographic methods that have been optimized for the separation of these compounds.</p>

<p>Tyrosinase protein:<br>Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is a human tyrosinase-derived (369-377) peptide by posttranslational conversion of the sequence YMNGTMSQV. Tyrosinase is an oxidase membrane-bound protein. Tyrosinase play a key role in the melanin synthesis pathway. Tyrosinase is presented on the surface of HLA-A*02:01 melanomas and also expressed in melanocytes. Tyrosinase has been still suggested to be a tumor antigen and might be implicated in improvement of immunotherapeutic strategies such as for efficient anticancer vaccine development.<br>Applications of Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV):<br>Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay. Peptide Tyrosinase (Asp371) – HLA-A*0201 (YMDGTMSQV) is also involved in experimental therapies of metastatic melanoma by allogeneic hematopoietic stem cell transplantation. In fact, cytotoxic T cells were generated from peripherical blood mononuclear cells (PBMCs) of HLA-A*02:01 healthy donors after being stimulated by injection of Asp371 antigen (2). This strategy raises issues which concern the graft versus tumor (GvT) effect and graft versus host disease (GvHD).</p>

<p>Amoxicillin trihydrate impurity B is an impurity of amoxicillin trihydrate, a penicillin antibiotic. Impurities are substances that are not intentionally added to the drug and may be formed during the manufacturing process. Impurities can affect the quality and safety of drugs, although their presence does not necessarily indicate a problem with the drug. Impurities in amoxicillin trihydrate include clavulanate potassium (impurity A) and heptane-2-carboxylic acid (impurity C). Impurity A is present in small quantities, typically less than 1% of the total amount of amoxicillin trihydrate. Impurity C is present in larger quantities and can make up to 10% of the total amount of amoxicillin trihydrate.</p>