Nucléotides
Les nucléotides sont des composés organiques qui servent de building blocks aux acides nucléiques, essentiels à la formation de l'ADN et de l'ARN. Chaque nucléotide est composé d'une base azotée, d'une molécule de sucre et d'un ou plusieurs groupes phosphate. Ces nucléotides s'assemblent pour former de longues chaînes, créant le matériel génétique qui porte et transmet l'information génétique dans tous les organismes vivants. Dans cette section, vous trouverez une large gamme de nucléotides essentiels pour la recherche en génétique, biologie moléculaire et biochimie. Ils sont fondamentaux pour étudier les processus génétiques, synthétiser des acides nucléiques et développer des outils diagnostiques et thérapeutiques. Chez CymitQuimica, nous proposons des nucléotides de haute qualité pour soutenir vos recherches scientifiques et applications, garantissant précision et fiabilité dans vos expériences.
Sous-catégories appartenant à la catégorie "Nucléotides"
2634 produits trouvés pour "Nucléotides"
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5'-Amino-5'-deoxythymidine
CAS :<p>5'-Amino-5'-deoxythymidine is a nucleoside that is structurally related to thymidine. It has been shown to be a substrate for fatty acid synthase, which is a key enzyme in the synthesis of membrane lipids. 5'-Amino-5'-deoxythymidine has been shown to induce tumorigenesis in mouse bladder carcinoma cells. This compound also does not form stable complexes with DNA duplexes and can inhibit uptake of thymidylate into cells by competitive inhibition. 5'-Amino-5'-deoxythymidine binds to the cell surface and acts as an antibody response modifier.</p>Formule :C10H15N3O4Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :241.24 g/mol3'-O-Benzoyl-2'-deoxyuridine
CAS :<p>3'-O-Benzoyl-2'-deoxyuridine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. 3'-O-Benzoyl-2'-deoxyuridine is also an antiviral agent that has shown efficacy against HIV, HSV, and influenza virus. 3'-O-Benzoyl-2'-deoxyuridine is a phosphoramidite monophosphate that can be used as a building block for DNA or RNA synthesis. It is also a diphosphate that can be used to synthesize modified nucleosides. This product has novel properties and high purity, making it suitable for research purposes.</p>Formule :C16H16N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :332.31 g/mol2'-Deoxy-5-hydroxyuridine
CAS :<p>2'-Deoxy-5-hydroxyuridine is a hydrated form of uracil that is used in the synthesis of nucleic acids. It is also a substrate for DNA polymerases and has been shown to inhibit the replication of herpes simplex virus. 2'-Deoxy-5-hydroxyuridine has been shown to have biological properties, such as inhibition of radiation-induced transformation, inhibition of cancer cell growth, and antiviral activity. The mechanism by which 2'-deoxy-5-hydroxyuridine inhibits the replication of herpes simplex virus is unclear but may be due to its ability to inhibit cellular metabolism.</p>Formule :C9H12N2O6Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :244.21 g/mol2',3'-Dideoxy-5'-O-DMT-cytidine
CAS :<p>2',3'-Dideoxy-5'-O-DMT-cytidine is a chemically modified cytidine nucleoside which can be used in synthetic chemistry, especially in nucleic acid synthesis. A dimethoxytrityl (DMT) protecting group is attached to the 5'-oxygen of the sugar. This is not biologically active, but it’s commonly used in solid-phase oligonucleotide synthesis to protect the 5' end during step-by-step DNA or RNA construction.</p>Formule :C30H31N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :513.6 g/mol8-(Benzyloxy)guanosine
CAS :<p>8-(Benzyloxy)guanosine is a novel nucleoside analog that is an activator of ribonucleotide reductase. It has been shown to inhibit the proliferation of cancer cells in vitro and in vivo, as well as inhibit the production of diphosphate from ATP. This compound also has antiviral activity against herpes simplex virus type 1 (HSV-1) and human immunodeficiency virus type 1 (HIV-1). 8-(Benzyloxy)guanosine is synthesized by reacting the 8-hydroxy group on guanosine with benzaldehyde, followed by phosphorylation with diphosphate. This compound has CAS No. 3868-36-8 and can be used for research purposes only.</p>Formule :C17H19N5O6Degré de pureté :Min. 95 Area-%Couleur et forme :White To Off-White SolidMasse moléculaire :389.36 g/molAdenosine 5'-monophosphate disodium salt
CAS :<p>Adenosine 5'-monophosphate disodium salt (AMP-Na2) is a chemical compound that has been used in the study of metabolic disorders. It belongs to the class of ethylene diamines and has been shown to increase the glomerular filtration rate. Ammonium adenosine 5'-monophosphate disodium salt has also been shown to increase the activity of glutamate decarboxylase, which converts glutamate into GABA, an inhibitory neurotransmitter. The neutral pH optimum for AMP-Na2 is 6.5-7.5, which may be due to its lysine residues. AMP-Na2 has a carbonyl group that can be oxidized by reactive oxygen species and cause oxidative injury to cells in vivo and in vitro. This damage was found mainly in microglia cells, which are responsible for removing dead or damaged neurons from the central nervous system (CNS). AMP-Na2 also activates ad</p>Formule :C10H12N5Na2O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :391.19 g/molInosine 5'-triphosphate disodium
CAS :<p>Inosine 5'-triphosphate disodium salt is a phosphoramidite that can be used as an activator for DNA synthesis. It also has antiviral and anticancer properties. Inosine 5'-triphosphate disodium salt is used in the synthesis of deoxyribonucleosides and other nucleotides.</p>Formule :C10H13N4O14P3•Na2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :552.13 g/molStavudine
CAS :<p>Anti-viral; reverse transcriptase inhibitor</p>Formule :C10H12N2O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :224.22 g/mol8-Azido-ATP-γ-biotin sodium
<p>8-Azido-ATP is a novel nucleoside that has been shown to be an activator of DNA and RNA synthesis in human cells. It is synthesized by the enzymatic transfer of a gamma-biotin moiety from ATP to dATP, resulting in 8-azido-ATP. This drug has antiviral and anticancer activity and has been shown to inhibit the replication of HIV. The 8-azido-ATP can be used as an activator for purine nucleotide incorporation into DNA or RNA, which may help with cancer treatment or prevention. 8-Azido-ATP also inhibits the growth of certain viruses, such as herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV).</p>Formule :C25H41N12O14P3S•NaxDegré de pureté :Min. 95%Couleur et forme :White/Off-White SolidMasse moléculaire :858.65 g/mol2'-Deoxyuridine-5'-triphosphate trisodium
CAS :<p>2'-Deoxyuridine-5'-triphosphate trisodium salt is a fluorophore that is excited by the absorption of light at wavelengths of 365 nm. The emission spectrum ranges from 380 to 500 nm and has a maximum at 480 nm. 2'-Deoxyuridine-5'-triphosphate trisodium salt can be used as a labeling agent for metal ion, molecule, or macrocyclic ligand. It can also be used as an acceptor in fluorescence energy transfer experiments.</p>Formule :C9H15N2O14P3•Na3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :537.11 g/mol5,6-Dihydro-5-azacytidine acetate
<p>5,6-Dihydro-5-azacytidine acetate is a monophosphate nucleoside that is used in the synthesis of DNA and RNA. It is an antiviral agent that inhibits the synthesis of DNA by preventing the conversion of deoxyribonucleotides to diphosphates. 5,6-Dihydro-5-azacytidine acetate has been found to have anticancer properties and is used in cancer treatment. This chemical also has a high purity and quality, making it a suitable reagent for use in phosphoramidite coupling reactions for oligonucleotide synthesis. 5,6-Dihydro-5-azacytidine acetate has been shown to be active against a variety of human tumor cell lines, including leukemia cells.</p>Formule :C10H17N4O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :305.26 g/molN4-Acetyl-2'-deoxycytidine
CAS :<p>N4-Acetyl-2'-deoxycytidine is a nucleoside analogue that acts as an inhibitor of DNA synthesis. It binds to the active site of the enzyme ribonucleotide reductase, blocking the conversion of ribonucleotides to deoxyribonucleotides. This prevents DNA synthesis and replication, which leads to cell death. N4-Acetyl-2'-deoxycytidine has been shown to be more efficient than other analogues in terms of energy efficiency, control levels, and constant linear model. This compound is reactive and can cause low yields when isolated from solutions with high concentrations. A diode can be used for analytical purposes, while calcium binding may be used as a mathematical model in order to analyze this drug.</p>Formule :C11H15N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :269.25 g/mol3-Deazaadenosine
CAS :<p>A potential role in apoptosis and cellular senescence.</p>Formule :C11H14N4O4Degré de pureté :Min. 99 Area-%Couleur et forme :PowderMasse moléculaire :266.26 g/mol7-Deaza-2'-deoxy-7-iodoadenosine
CAS :<p>7-Deaza-2'-deoxy-7-iodoadenosine is an oligomer with a stabilized backbone that has been shown to inhibit the growth of bacteria in vitro. It binds to DNA and prevents RNA synthesis. 7-Deaza-2'-deoxy-7-iodoadenosine is a synthetic nucleotide analogue that is used as a probe for mapping RNA sequences and as an inhibitor of bacterial growth. This compound is also used in the synthesis of oligodeoxynucleotides because it has a high affinity for guanine residues, which can be incorporated into the oligonucleotide chain by chemical ligation. The octameric form of 7-deaza-2'-deoxyadenosine is most active against bacterial cells.</p>Formule :C11H13IN4O3Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :376.16 g/molLamivudine 5'-triphosphate triethylammonium salt (Ethanol solution)
CAS :<p>Sold by weight of nucleoside as solution in ethanol.</p>Formule :C20H46N5O12P3SDegré de pureté :Min. 95%Couleur et forme :Clear LiquidMasse moléculaire :673.59 g/mol7-Allyl-7,8-dihydro-8-oxoguanosine
CAS :<p>Agonist of toll-like receptors TLR7</p>Formule :C13H17N5O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :339.3 g/mol5'-Azido-5'-deoxythymidine
CAS :<p>5'-Azido-5'-deoxythymidine is a synthetic analogue of thymidine. The compound has been synthesised and fluorescently labelled with ferrocene. 5'-Azido-5'-deoxythymidine is not cytotoxic to cancer cells, but it is shown to be an effective inhibitor of DNA synthesis by binding to the enzyme DNA polymerase. This causes a decrease in the rate of DNA synthesis and thus inhibits cancer cell growth.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/mol2'-Deoxy-5'-O-DMT-5-iodouridine
CAS :<p>2'-Deoxy-5'-O-DMT-5-iodouridine is an intercalating agent that binds to DNA and RNA. It can be used as a probe for the detection of specific sequences in human cells. The fluorophore attached to the molecule allows it to be detected by fluorescence microscopy, while the chromophore is responsible for its ability to emit light at a wavelength of 535 nm. 2'-Deoxy-5'-O-DMT-5-iodouridine has been shown to enhance nucleotide excision repair and increase the sensitivity of cancer cells to chemotherapy drugs such as cisplatin. The molecule can also be used as a fluorescent protein marker in her-2 gene amplification and overexpression studies.</p>Formule :C30H29IN2O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :656.48 g/molN4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine
CAS :<p>N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a synthetic nucleoside that is used as an activator for DNA synthesis. It is also used in the preparation of diphosphate derivatives for use as antiviral and anticancer agents or as probes for DNA and RNA research. N4-Benzoyl-3'-deoxy-5'-O-DMT-cytidine is a novel, high purity, and high quality chemical with CAS No. 86234-45-9.</p>Formule :C37H35N3O7Degré de pureté :Min. 95%Masse moléculaire :633.69 g/mol8-Chloroadenosine
CAS :<p>8-Chloroadenosine is a potent inhibitor of apoptosis, which is the process by which cells die. It has been shown to inhibit cell growth in murine hepatoma cells and synergize with other cytotoxic agents. 8-Chloroadenosine inhibits the activity of bcl-2 protein and thus blocks the release of cytochrome c from mitochondria. This causes DNA damage by inhibiting DNA synthesis and protein synthesis, leading to apoptosis. 8-Chloroadenosine has also been shown to be an active inhibitor of cancer cells, especially myeloma cell lines. The response element for 8-chloroadenosine is located in the promoter region of the gene encoding cyclooxygenase 2 (COX-2), which encodes a protein that produces prostaglandins involved in inflammation and tumor growth. The concentration of camp in cancer tissues determines whether these cells will respond favorably or unfavorably to this drug.</p>Formule :C10H12ClN5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :301.69 g/molDenufosol tetrasodium
CAS :<p>A P2Y2 receptor agonist that has been studied in cystic fibrosis and retinal diseases such as retinal detachment. Denufosol was studied as an inhaled drug for cystic fibrosis, due to its ability to activate an alternative chloride channel and avoiding the defective CFTR chloride channel. This enhances hydration of the lung mucosa and improves mucociliary clearance. The drug did not progress from phase III clinical trials. Denufosol resulted in subretinal fluid reabsorption in in vivo model of retinal detachment.</p>Formule :C18H23N5Na4O21P4Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :861.25 g/mol3'-Amino-3'-deoxyadenosine
CAS :<p>3'-Amino-3'-deoxyadenosine, also known as spalgomycin, is a natural enediyne antibiotic with potent antibacterial and, more notably, antitumor activity observed in research settings. Its primary use is as a tool to study the mechanisms of enediyne-mediated DNA damage and as a lead compound in the search for novel anticancer therapeutics.</p>Formule :C10H14N6O3Couleur et forme :White Off-White PowderMasse moléculaire :266.26 g/mol2',3'-Dideoxy-5-methylcytidine
CAS :<p>2',3'-Dideoxy-5-methylcytidine is a synthetic nucleoside analog based on cytidine, a natural building block of DNA and RNA. This molecule is chemically modified to interfere with nucleic acid synthesis, making it a potential tool in antiviral or anticancer therapy, or for studying epigenetics.</p>Formule :C10H15N3O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :225.25 g/mol2'-Deoxycytidine-5'-monophosphate
CAS :<p>2'-Deoxycytidine-5'-monophosphate (dCMP) is a nucleotide that is synthesized by the enzyme cytidine monophosphate synthetase. It has been shown to inhibit the activity of many enzymes, including those involved in DNA synthesis and repair. The incorporation of dCMP into DNA can be used as a probe for studying various biological processes, such as radiation damage and cellular physiology. In addition, it has been shown that dCMP inhibits the growth of human osteosarcoma cells. This drug is also used in combination preparations with other drugs, such as with 5-fluorouracil and doxorubicin, to treat cancer tumors.</p>Formule :C9H14N3O7PDegré de pureté :Min. 99 Area-%Couleur et forme :White PowderMasse moléculaire :307.2 g/molAcetoacetyl coenzyme A lithium salt
CAS :<p>Acetoacetyl coenzyme A lithium salt is a novel phosphoramidite building block. It's a modified nucleoside that can be used in the synthesis of oligonucleotides and DNA. Acetoacetyl coenzyme A lithium salt has antiviral, anticancer, and antifungal activities.</p>Formule :C25H36N7O18P3SLi4·5H2ODegré de pureté :Min. 96 Area-%Couleur et forme :PowderMasse moléculaire :965.42 g/molCytidyl-3'-5'-uridine ammonium
CAS :<p>Cytidyl-3'-5'-uridine ammonium salt is a nucleoside analog that is used as an antiviral and anticancer agent. Cytidyl-3'-5'-uridine ammonium salt inhibits the synthesis of DNA by inhibiting the activity of enzymes such as DNA polymerase, RNA polymerase, or reverse transcriptase. It also has antitumor properties and can be used to treat leukemia and other types of cancer. Cytidyl-3'-5'-uridine ammonium salt has been shown to be more potent than cytidyl-2',4',6'-triaminopyrimidine (CTAP) in inhibiting the growth of lymphocytic leukemia cells.</p>Formule :C18H24N5O13P•NH3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :566.42 g/molN6-Benzoyl-5'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-5'-O-DMT-adenosine is a synthetic nucleoside with antiviral activity. It is an activator of viral DNA polymerase and inhibits viral replication by inhibiting DNA synthesis in the host cell. N6-Benzoyl-5'-O-DMT-adenosine has shown anticancer activity in tumor cells, which may be due to its ability to inhibit ribonucleotide reductase and diphosphate kinase.</p>Formule :C38H35N5O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :673.73 g/molN4-Acetylcytidine
CAS :<p>N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.</p>Formule :C11H15N3O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :285.25 g/molN6-Benzoyl-3'-O-methyladenosine
CAS :<p>N6-Benzoyl-3'-O-methyladenosine is a novel modified nucleoside that has antiviral activity. It has been shown to possess high purity and high quality, and can be used as an activator for DNA synthesis. N6-Benzoyl-3'-O-methyladenosine is synthesized from 3'-O-methyladenosine with the use of phosphoramidites, ribonucleosides, or monophosphate nucleotides. The compound is CAS No. 85090-30-8 and is soluble in water.</p>Formule :C18H19N5O5Degré de pureté :Min. 96 Area-%Couleur et forme :Off-White PowderMasse moléculaire :385.37 g/molAdenosine 2',3'-cyclic monophosphate sodium
CAS :<p>Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.</p>Formule :C10H11N5NaO6PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :351.19 g/mol5-(Azidomethyl)-2’-deoxyuridine
CAS :<p>5-azidomethyl-2-deoxyuridine (AmdU) is a nucleoside that contains an azide group. The structure of the nucleoside is similar to thymidine, and it is incorporated into nascent DNA by cellular polymerases, similarly to EdU (NE08701). Unlike EdU that needs to be further modified with azides in the presence of copper catalyst, AmdU can also react in the absence of copper catalyst using spAAC Click Chemistry with strained cycloalkynes, such as cyclooctynes. This enables detection of nascent DNA in benign, copper free conditions.</p>Formule :C10H13N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.24 g/mol2'-O-(2-Methoxyethyl)adenosine
CAS :<p>2'-O-(2-Methoxyethyl)adenosine is a nucleoside derivative that is produced by the methylation of 2'-deoxyadenosine. It is used in organic synthesis as a reagent for the alkylation of aromatic hydrocarbons and as an intermediate in the synthesis of purines. The product can be isolated with yields of 78% or greater, depending on reaction conditions and purification methods. Isomeric purity can be achieved with high purity (>99%) by recrystallization from water or ethanol. The compound has a number of physical properties that are similar to those of adenosine, including boiling point, melting point, density, and refractive index. The molecule also has two chiral centers at C2 and C4 that contribute to its isomeric nature. Adenosine is found in human connective tissue cells, where it plays a role in cell metabolism by regulating the production of RNA and DNA.</p>Formule :C13H19N5O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :325.32 g/mol2-Chloro-6-O-methylinosine
CAS :<p>2-Chloro-6-O-methylinosine is a modified nucleoside analog. Its structure is based on inosine and at position 2 a chlorine atom replaces the hydrogen. At position 6, the keto oxygen (normally part of the purine ring) is O-methylated, forming a methoxy group (-OCH₃)</p>Formule :C11H13ClN4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :316.7 g/molL-Adenosine 5'-monophosphate disodium
CAS :<p>L-Adenosine 5'-monophosphate disodium is a high quality, novel, modified phosphoramidite used for the synthesis of deoxyribonucleosides and nucleosides. It is also used as an antiviral agent and has anti-cancer properties. L-Adenosine 5'-monophosphate disodium is an activator of ribonucleoside activities and inhibits viral replication by inhibiting the enzyme RNA polymerase. It has been shown to be effective against HIV, herpes simplex virus (HSV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), influenza A virus, and influenza B virus.</p>Formule :C10H12N5Na2O7PDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :391.18 g/mol8-Bromoinosine
CAS :<p>8-Bromoinosine is a potent chemical probe that can be used to study the molecular mechanism of cGMP-dependent protein kinase (PKG). 8-Bromoinosine reacts with the acceptor site in PKG, which is located at the base of the active site cleft. Electrons from hydrogen bond donor sites on 8-bromoadenosine are transferred to chloride ion and the resulting 8-bromoinosine chloride complex is an effective inhibitor of PKG. It has been shown that stereoselectivity plays a role in this reaction mechanism.</p>Formule :C10H11BrN4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :347.13 g/molPseudothymidine
CAS :<p>Pseudothymidine is the nucleobase analog of thymidine. It is a synthetic substance that has been used in the polymerase chain reactions (PCRs) to form DNA molecules. Pseudothymidine is not naturally found in cells and can be used as a substitute for thymidine during PCR to make more copies of DNA sequences. It has been shown that pseudothymidine can be incorporated into DNA without disrupting the polymerase chain reaction. The thermal denaturation of pseudothymidine is 10 °C lower than that of thymidine, allowing it to be used at higher temperatures with less risk of degradation.</p>Formule :C10H14N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :242.23 g/mol1-(β-D-Arabinofuranosyl)cytosine 5'-monophosphate
CAS :<p>1-(β-D-Arabinofuranosyl)cytidine 5'-monophosphate (ara-CMP) is a nucleotide derivative of cytidine, specifically a nucleotide where the ribose sugar is replaced by the arabinose sugar. It's a pyrimidine nucleotide commonly known as Cytarabine 5'-monophosphate or arabinosylcytosine 5'-monophosphate.</p>Formule :C9H14N3O8PDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :323.2 g/molClofarabine
CAS :<p>Clofarabine is FDA-approved for treating relapsed or refractory acute lymphoblastic leukaemia (ALL) in children after at least two other types of treatment have failed</p>Formule :C10H11ClFN5O3Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :303.68 g/mol2-Amino-9-(β-D-ribofuranosyl)purine
CAS :<p>2-Amino-9-(β-D-ribofuranosyl)purine is a purine nucleoside consisting of the base 2-aminopurine linked via an N9-glycosidic bond to β-D-ribofuranose. As an analog of adenosine, it retains structural compatibility with nucleic acids but exhibits distinct biochemical properties, most notably intrinsic fluorescence. This makes it a valuable probe in molecular biology for studying nucleic acid structure, base pairing, and conformational changes, as its fluorescence is sensitive to local stacking interactions and environmental conditions.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/mol5'-O-DMT-N2-DMF-guanosine
CAS :<p>5'-O-DMT-N2-DMF-guanosine is a novel nucleoside that has been modified with an acetyl group on the 5'-hydroxyl group. This nucleoside has antiviral, anticancer and deoxyribonucleoside properties. It also activates diphosphate synthesis and inhibits protein synthesis. The drug is synthesized in high purity and quality, making it an excellent activator for phosphoramidites.</p>Formule :C34H36N6O7Degré de pureté :(%) Min. 85%Masse moléculaire :640.69 g/mol3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine
CAS :<p>3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine is an antiviral drug that inhibits the synthesis of viral DNA and RNA. This antiviral drug is a novel synthetic nucleoside analogue that is phosphorylated to form monophosphate, which inhibits the synthesis of RNA. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine has been shown to be effective against cancer cells by inhibiting ribonucleotide reductase and DNA synthesis. 3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine also inhibits DNA synthesis by blocking the enzymes DNA polymerase and deoxyribonucleoside kinase.</p>Formule :C17H16N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :380.36 g/mol2-Amino-6-chloro-9-(b-D-ribofuranosyl)purine
CAS :<p>Intermediate in the synthesis of nelarabine</p>Formule :C10H12ClN5O4Degré de pureté :Min. 97 Area-%Couleur et forme :Off-White PowderMasse moléculaire :301.69 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine
CAS :<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine is a synthetic nucleoside that is used in the synthesis of RNA. It has been shown to be resistant to heat and both acidic and basic conditions. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine can be used for modifications of oligonucleotides and as a convenient sealant for the synthesis of DNA, RNA, or other nucleic acids. This product is neutralized with hydrochloric acid prior to use.</p>Formule :C36H44N2O8SiDegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :660.83 g/mol3-(3-Acetamido-3-carboxypropyl)uridine
CAS :<p>acetylated derivative from 3-(3-amino-3-carboxypropyl)uridine</p>Formule :C15H21N3O9Degré de pureté :Min. 95%Couleur et forme :SolidMasse moléculaire :387.34 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine
CAS :<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine is a novel nucleoside analog with antiviral, anticancer and immunomodulatory activities. It has been shown to inhibit the replication of HIV-1 and to induce apoptosis in tumor cells. N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine is a phosphoramidite that can be used for the synthesis of DNA, RNA, and deoxyribonucleotides. This product is synthesized by using an automated high purity process.</p>Formule :C38H35N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :657.73 g/mol3'-O-Methylguanosine 5'-triphosphate lithium
CAS :<p>3'-O-Methylguanosine 5'-triphosphate lithium is a nucleotide that has been synthesized and characterized. It is a biochemical regulatory molecule that is involved in the synthesis of DNA, RNA, and proteins. 3'-O-Methylguanosine 5'-triphosphate lithium binds to the guanine nucleotide binding protein G, which acts as an allosteric activator of the enzyme ribonucleotide reductase. The reconstituted enzyme system containing 3'-O-methylguanosine 5'-triphosphate lithium has demonstrated a high level of fidelity in the replication of dna templates.</p>Formule :C11H18N5O14P3•Li4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :564.97 g/molN4-Benzoyl-5'-O-DMT-2'-O-methylcytidine
CAS :<p>N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is an antiviral agent that inhibits the replication of a number of DNA viruses, including herpes simplex virus type 1 and type 2. It is a monophosphate inhibitor that binds to the ribonucleotide reductase enzyme, preventing formation of deoxyribonucleotides. N4-Benzoyl-5'-O-DMT-2'-O-methylcytidine is also used as an anticancer agent. This drug has been shown to inhibit the growth of human leukemia cell cultures and can be used for treatment of leukemia in combination with other drugs. The novel properties of this compound make it useful for research purposes and it has been synthesized in high quality at low cost.</p>Formule :C38H37N3O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :663.72 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine
CAS :<p>4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine (4FA) is a potent inhibitor of the growth of HIV. It has been shown to inhibit the production of inflammatory cytokines and chemokines, which are associated with inflammatory diseases such as arthritis and asthma. 4FA has also been shown to inhibit glycogen synthase kinase 3 (GSK3), which is involved in the regulation of cellular signaling pathways that control cell growth and proliferation. Furthermore, 4FA inhibits an enzyme that is needed for viral replication and can be used as a therapeutic agent against viruses such as hepatitis C virus.</p>Formule :C9H11FN6O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :286.22 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a nucleoside that can be used in the synthesis of oligomers. It is a synthetic nucleoside with an absorption maximum at 410 nm and emission maximum at 522 nm. This compound has been shown to be efficient in the synthesis of phosphoramidites and ligands, as well as in rna synthesis and modifications. N6-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine may inhibit bacterial growth by binding to the ribosome, preventing protein synthesis.</p>Formule :C44H49N5O7SiDegré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :787.97 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>Membrane-permeable brominated cAMP analog and activator of cAMP-dependent protein kinase A (PKA). In stem cell research, the compound enhanced the induction of pluripotency and efficiency of cellular reprogramming of human neonatal fibroblasts that were transduced with different transcription factors.</p>Formule :C10H10BrN5O6P·NaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :430.08 g/molN6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine
<p>N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine is a nucleoside analog that inhibits the activity of HIV reverse transcriptase. It is an antiviral agent that prevents the synthesis of viral DNA by competitively inhibiting the incorporation of deoxynucleotide triphosphates into viral DNA. This drug also has been shown to be effective against cytomegalovirus (CMV), herpes simplex virus, and varicella zoster virus (VZV). N6-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)adenosine has been synthesized with phosphoramidites and purified to high quality standards. The chemical structure includes a modified sugar moiety, an altered base moiety, and a unique phosphate group.</p>Formule :C41H41N5O8Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :731.79 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol
CAS :<p>1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N4-benzoylcytidin-1-yl)-D-altro-hexitol is a synthetic nucleoside analog for use in research</p>Formule :C24H22N2O7Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :450.45 g/molS-Adenosyl-L-methionine disulfate tosylate
CAS :<p>S-Adenosyl-L-methionine disulfate tosylate (SAMe) is a dietary supplement that is used to treat depression and liver disease. It is also a metabolite of the amino acid methionine, which is formed by the enzyme S-adenosylmethionine synthase. SAMe has been shown to inhibit the activation of caspase 3, which causes apoptosis in cells, and may be useful for treating cancer and other diseases. The chromatographic method used to separate SAMe from other compounds relies on its evaporative properties, due to its high water solubility.</p>Formule :C22H34N6O16S4Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :766.8 g/molAdenosine-5'-O-diphosphoribose phosphate
CAS :<p>Potential metabolite of NADP+</p>Formule :C15H24N5O17P3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :639.3 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine
CAS :<p>N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine is a modified nucleoside that is used in the synthesis of oligonucleotides. It is an activator of DNA and RNA synthesis, which has antiviral and antitumor properties. The CAS number for this compound is 81256-88-4.</p>Formule :C44H49N5O7SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :787.97 g/mol6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS :<p>6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.</p>Formule :C10H12N4O3SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :268.29 g/molN6-Benzoyl-2',3'-isopropylideneadenosine
CAS :<p>N6-Benzoyl-2',3'-isopropylideneadenosine is a nucleoside that is structurally related to the natural nucleosides adenosine, deoxyadenosine, and deoxyguanosine. It is an antiviral agent that has been shown to be an activator of the enzyme ribonucleotide reductase. N6-Benzoyl-2',3'-isopropylideneadenosine is a modified nucleoside with high purity and high quality. The CAS number for this compound is 39947-04-1. This compound has not been found in nature, but it can be synthesized by modifying nucleosides or by using phosphoramidites.</p>Formule :C20H21N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :411.41 g/mol6-Benzylamino-9-(b-D-arabinofuranosyl)purine
CAS :<p>6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a nucleoside that is used as an activator and as an antiviral agent. It has been used in anticancer research, but it has not been found to have any significant effect against cancer cells. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine is a modified ribonucleoside with a boronic acid group attached to the 9 position of the purine ring. This modification leads to increased stability of the nucleotide in alkaline conditions and improved cellular uptake. 6-Benzylamino-9-(b-D-arabinofuranosyl)purine can be phosphorylated on the 2',3' and 5' positions, forming 2',3'-diphosphate, 3'-diphosphate and 5'-triphosphate derivatives.</p>Formule :C17H19N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :357.37 g/mol8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium
CAS :<p>8-Bromoadenosine 3',5'-cyclic monophosphorothioate, Rp-isomer sodium salt (8-BrAMP) is an activated analog of adenosine that binds to the cyclase enzyme and inhibits its activity. It has been shown to inhibit the production of epidermal growth factor in a model system. 8-BrAMP also blocks the synthesis of cyclic nucleotides by inhibiting cyclic nucleotide phosphodiesterase, which results in increased levels of cAMP. 8-BrAMP has been shown to inhibit HIV infection by acting as a transcription-polymerase chain inhibitor and blocking HIV mRNA synthesis. The drug also inhibits cell lysis by binding to calmodulin and β-catenin.</p>Formule :C10H11BrN5O5PS•NaDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :447.16 g/molN4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine
CAS :<p>N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a nucleoside monophosphate with antiviral and anticancer activity. It is used as an activator for the synthesis of oligodeoxynucleotides and may be used in the treatment of herpes zoster, AIDS, or cancer. N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine has a novel structure that is modified from natural nucleosides and has been shown to have high purity.</p>Degré de pureté :Min. 97.0 Area-%Couleur et forme :PowderMasse moléculaire :445.60 g/mol5'-Deoxy-5-fluorouridine
CAS :<p>5'-Deoxy-5-fluorouridine (5FU) is a nucleoside that is used in the treatment of cancer. It is an antimetabolite that inhibits the synthesis of DNA, RNA, and proteins by reversibly inhibiting ribonucleotide reductase. 5FU also inhibits epidermal growth factor receptor (EGFR), which leads to apoptosis in cancerous cells. The concentration–time curve for 5FU has been determined using tissue culture and hl-60 cells as biological samples. This drug has been shown to be effective against metastatic colorectal cancer when administered with other chemotherapeutic drugs.</p>Formule :C9H11FN2O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :246.2 g/mol3'-Amino-N6-benzoyl-2',3'-dideoxy-5'-O-DMT-adenosine
<p>A valuable chemical tool for synthesizing modified oligonucleotides with specific functionalities at the 3' end, primarily used in oligonucleotide synthesis.</p>Formule :C38H36N6O5Degré de pureté :Min. 95%Masse moléculaire :656.73 g/mol5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine
CAS :<p>5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine is a nucleoside that can be used as an activator for ribonucleosides. It has been shown to have anticancer, antiviral and antiviral activities. 5'-O-tert-Butyldimethylsilyl-2'-deoxy-5-iodocytidine is synthesized by the reaction of 2'-deoxycytidine with tertbutyldimethylchlorosilane in the presence of triethylamine. The product may be purified by crystallization or chromatography.</p>Formule :C15H26IN3O4SiDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :467.38 g/molAdenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt
CAS :<p>Adenosine 3',5'-cyclic monophosphothioate Sp-isomer sodium salt (CMPT) is a neurotrophic factor that belongs to the class of adenosine 3',5'-cyclic monophosphates. It has been shown to induce neuronal differentiation and neurite outgrowth in a model system. CMPT has also been shown to have neuroprotective effects by ameliorating the severity of Parkinson's disease symptoms. This drug has been shown to increase body mass index and IGF-I levels in vivo. CMPT has been demonstrated to inhibit tumor growth through upregulation of the cytosolic Ca2+ level, which leads to apoptosis. CMPT can be used as a pharmacological treatment for Alzheimer's disease, Parkinson's disease, and other neurodegenerative disorders.</p>Formule :C10H11N5O5PS·NaDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :367.25 g/mol3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxy-N2-DMF-guanosine
CAS :<p>3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxy-N2-DMF-guanosine is a phosphoramidite nucleoside that is synthesized by the reaction of 2'-deoxyguanosine and dimethyldichlorosilane. This product has anticancer activity, as it inhibits DNA synthesis and topoisomerase II activity. It also has antiviral effects, as it inhibits viral RNA synthesis. 3',5'-Di-O-(tert-butyldimethylsilyl)-2'-deoxy-N2-DMF-guanosine has been shown to be more stable than its corresponding 5'-di-O-(tert-butyldimethylsilyl) analogue, with a half life of greater than 10 hours in phosphate buffered saline at 37°C.</p>Formule :C25H46N6O4Si2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :550.84 g/mol5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt
CAS :<p>5-Bromo-2'-deoxyuridine-5'-monophosphate sodium salt (BrdUMP) is an antiviral agent that inhibits the synthesis of DNA. It has shown activity against herpes simplex virus and cytomegalovirus, and has been used in the treatment of Kaposi's sarcoma. BrdUMP is a monophosphate prodrug that is activated by ribonucleoside diphosphates to inhibit the production of viral DNA and RNA. This drug has anticancer properties due to its ability to inhibit cell division. BrdUMP is synthesized from 2'-deoxyuridine-5'-monophosphate, which is obtained from uracil or thymine. The CAS number for this compound is 51432-32-7, and it can be used as a phosphoramidite for the preparation of DNA, RNA, or oligonucleotide analogues.</p>Formule :C9H12BrN2O8PNa2Degré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :433.06 g/molAdenosine 5'-diphosphate magnesium salt
CAS :<p>Adenosine 5'-diphosphate magnesium salt (ADP-Mg) is a pharmacological agent that has inhibitory properties. It is used as a model system to study platelet function and the effect of adenosine on platelet aggregation. ADP-Mg is also used as a reagent in the study of protein synthesis and regulation. This chemical has been shown to potentiate the activity of serotonin receptors, which may contribute to its anti-inflammatory effects. Adenosine 5'-diphosphate magnesium salt also inhibits papillary muscle contractions by inhibiting Ca2+ currents, leading to an improved ejection fraction in patients with congestive heart failure.</p>Formule :C10H13N5O10P2·MgDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :449.49 g/mol3'-Azido-N4-benzoyl-2',3'-dideoxycytidine
CAS :<p>3'-Azido-N4-benzoyl-2',3'-dideoxycytidine is a novel nucleoside analog with antiviral and anticancer activities. It is used for the treatment of HIV, hepatitis B and C, herpes, and influenza. 3'-Azido-N4-benzoyl-2',3'-dideoxycytidine has been shown to inhibit the proliferation of cells in culture and to induce apoptosis in various cancer cell lines.<br>The synthesis of 3'-azido-N4-benzoyl-2',3'-dideoxycytidine starts with the condensation of 4-(hydroxymethyl)phenylacetic acid (1) with 2,6-dichloroisonicotinic acid chloride (2) in the presence of triethylamine to give 4-(hydroxymethyl)phenylacetic acid chloride (3). The N4 benzoyl</p>Formule :C16H16N6O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :356.34 g/mol6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine
CAS :<p>6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine is a synthetic nucleoside with antiviral and anticancer activity. It is an activator of the DNA polymerase, which is involved in the synthesis of DNA. The high purity of this product makes it a good choice for use in research or as a starting material for further chemical modification. 6-Chloro-9-(2'-deoxy-3',5'-di-O-toluoyl-b-ribofuranosyl)purine has been shown to inhibit the growth of cancer cells, including breast, lung and colon carcinoma cells.</p>Formule :C26H23ClN4O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :506.95 g/molN4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS :<p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a modified nucleoside with anticancer and antiviral properties. It is used in the synthesis of oligonucleotides as an activator, DNA or RNA. This product is also used as a phosphoramidite for the preparation of oligonucleotides. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT cytidine has a CAS Number of 8125687.</p>Formule :C43H49N3O8SiDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :763.95 g/molN6-Benzoyl-5'-O-DMT-2'-O-methyladenosine
CAS :<p>N6-Benzoyl-5'-O-DMT-2'-O-methyladenosine is a novel nucleoside that is structurally related to adenosine. It is synthesized through the reaction of N6-benzoyladenine with 2'-O-methyladenosine. This nucleoside has been shown to be an effective antiviral and anticancer agent.</p>Formule :C39H37N5O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :687.76 g/mol8-Bromoadenosine 3',5'-cyclic monophosphate
CAS :<p>8-Bromoadenosine 3',5'-cyclic monophosphate (8-Br-cAMP) is a cyclic nucleotide that is involved in the regulation of energy metabolism. It is a pharmacological agent that regulates the intracellular levels of cAMP and plays an important role in regulating cell proliferation, differentiation, and survival. 8-Br-cAMP binds to specific protein kinases and alters their activity. It also inhibits the enzymatic activity of DNA polymerase II. 8-Br-cAMP has been shown to inhibit tumor growth in mice with bone cancer. The mechanism by which this drug exerts its antitumor effect appears to be related to increased expression of basic proteins and decreased expression of phosphatase 2A, leading to increased activation of protein kinase A. 8-Br-cAMP also causes cellular accumulation of Ca2+ ions by stimulating an increase in the activity of phospholipase C, which hydrolyzes phosphat</p>Formule :C10H11BrN5O6PDegré de pureté :Min. 98 Area-%Couleur et forme :Beige PowderMasse moléculaire :408.11 g/mol1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N8-(dimethylamino)methyleneguanidin-1-yl)-D-altro-hexitol
CAS :<p>1,5-Anhydro-3-O-benzoyl-4,6-O-benzylidene-2-deoxy-2-(N8-(dimethylamino)methyleneguanidin-1-yl)-D-altro-hexitol is a synthetic, protected nucleoside analog built on a D-altro-hexitol backbone — which is a six-carbon sugar alcohol structure — and it includes a highly modified guanidine-like base at the 2-position. It has possible applications in synthetic nucleic acid chemistry</p>Formule :C28H28N6O6Degré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :544.57 g/molP1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt
CAS :<p>P1-(5'-Adenosyl) P3-(5'-adenosyl) triphosphate sodium salt is an intermediate in the biosynthesis of ATP. It is also a cofactor for adenylate kinase and pyruvate kinase. The synthesis of this compound takes place in human serum and requires the enzyme synthetase as well as sephadex g-100. Synthetase catalyzes the condensation of ATP with 5-AMP to yield P1-(5'-adenosyl) P3-(5'-adenosyl) triphosphate sodium salt. This reaction is reversible, and can be catalyzed by phosphohydrolases that hydrolyze ATP to AMP and inorganic phosphate. The physiological function of this compound is not yet clear, but it has been shown to increase intracellular Ca2+ levels in cardiac cells, leading to congestive heart failure. This compound has low potency, so it does not have any</p>Formule :C20H27N10O16P3•(Na)xDegré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :756.41 g/mol3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine
CAS :<p>3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine is a nucleoside monophosphate with antiviral activity. It is a synthetic nucleoside that has been modified to be resistant to degradation by ribonucleases. 3',5'-Di-O-acetyl-2'-deoxy-2'-fluorouridine inhibits the synthesis of DNA, RNA and protein and is used for treatment of cancer. This drug is not active against other types of viruses such as herpes simplex virus or cytomegalovirus.</p>Formule :C13H15FN2O7Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :330.27 g/mol5'-Amino-5'-deoxyadenosine hydrochloride
CAS :<p>5'-Amino-5'-deoxyadenosine hydrochloride (5'-ADeA) is a nucleotide that is synthesized from ribose 5-phosphate and adenosine monophosphate. It has been shown to have potential as a biomarker for skin cancer. The synthesis of 5'-ADeA is catalyzed by the enzyme caffeic acid 4-monooxygenase, which converts caffeic acid into 5'-ADeA. This reaction requires molecular oxygen, NADPH, and iron ions. The activity of this enzyme can be inhibited by sodium carbonate or basic fibroblast growth factor (bFGF). This drug has been shown to have anti-inflammatory effects in vivo.</p>Formule :C10H14N6O3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :266.26 g/molAdenosine 3',5'-cyclic monophosphate sodium salt
CAS :<p>Second messenger in intracellular signal transduction</p>Formule :C10H11N5NaO6PDegré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :351.19 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt
CAS :<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-O-succinate triethylamine salt is a synthetic antiviral agent that can be used in the treatment of HIV. This drug inhibits the viral DNA polymerase and prevents virus replication. N4-Benzoyl-2'-deoxy-5'-O-DMT cytidine 3'-O succinate triethylamine salt is a novel nucleoside analogue with a monophosphate group at the 5' position and an N4 benzoyl group at the 2' position. It is an activator of DNA synthesis, which can be used for cancer chemotherapy. The chemical name for this drug is CAS No. 74405-44-0 (free base).</p>Formule :C41H39N3O10·C6H15NDegré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :834.95 g/mol8-Azidoadenosine 3',5'-cyclic monophosphosphate free acid
CAS :<p>8-Azidoadenosine 3',5'-cyclic monophosphosphate is used for nucleotide labelling via a click reaction involving the azide moiety and a terminal alkyne conjugated to a label. The reaction generates a stable nucleotide labelled adduct containing a triazole link.</p>Formule :C10H11N8O6PDegré de pureté :Min. 95%Couleur et forme :White to pale yellow solid.Masse moléculaire :370.22 g/molXanthosine
CAS :Produit contrôlé<p>Xanthosine is a purine nucleoside that is formed from the metabolism of adenosine. Xanthosine can be phosphorylated to form xanthosine 5'-monophosphate (XMP), which has been shown to have biochemical properties and metabolic responses in vitro. The p-hydroxybenzoic acid moiety of xanthosine has been shown to have therapeutic potential for the treatment of inflammatory diseases, such as rheumatoid arthritis. It also has a role in the regulation of disease activity, as it is found at high concentrations in human serum, and regulates the proliferation of cells through its binding to nuclear proteins. Xanthosine is an important component of dinucleotide phosphate (NDP) pools that are essential for cell nuclei function. NDPs are also important for DNA synthesis and repair, as well as protein synthesis. Xanthosine 5'-monophosphate can act as a metal chelate and is used in</p>Formule :C10H12N4O6Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :284.23 g/moltrans-Zeatin-o-glucoside riboside
CAS :<p>Trans-Zeatin-o-glucoside riboside is a nucleotide that is found in protonemata and is involved in the regulation of cell division, cytokinin production, and responses to light. It is a cytokinin that regulates the pathways of nitrogen metabolism and other metabolic pathways. Trans-Zeatin-o-glucoside riboside has been detected at detectable levels in cells, tissues, and fluids. It has been shown to be involved in the evolution of plants. It has been shown to regulate cell division by inhibiting the phosphorylation of fibrillarin protein kinase, which leads to an increase in cyclins D1/D2 with no change in cyclin E1/E2. This nucleotide may also play a role in regulating cytokinin production by binding to DNA and influencing gene transcription.</p>Formule :C21H31N5O10Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :513.5 g/mol3'-O-Allyladenosine
CAS :<p>3'-O-Allyladenosine is an antiviral agent that inhibits the replication of DNA and RNA viruses. It has been shown to have anticancer properties, and is a novel nucleoside analog with potential as an antitumor agent. 3'-O-Allyladenosine is a modified nucleoside analog that can be synthesized with high purity and quality. This compound has shown antiviral activity against influenza virus and herpes simplex virus type 1. In addition, 3'-O-Allyladenosine has been found to inhibit tumor growth in mice without any significant side effects.</p>Formule :C13H17N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :307.31 g/mol8-Azidoadenosine
CAS :<p>8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.</p>Formule :C10H12N8O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :308.25 g/molRibavirin 5'-diphosphate lithium
CAS :<p>Ribavirin is an antiviral drug that inhibits the production of viral RNA. Ribavirin 5'-diphosphate is formed in the liver through sequential actions of kinases.</p>Formule :C8H14N4O11P2•Li2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :418.03 g/molN4,3'-O-Dibenzoyl-2'-deoxycytidine
CAS :<p>N4,3'-O-Dibenzoyl-2'-deoxycytidine is a nucleoside that functions as a base. It is a diester of the naturally occurring nucleoside cytidine and 2′,6′-dibenzoyl-deoxyribose. The compound has been shown to be an inhibitor of DNA polymerases and nuclease activity in vitro. N4,3'-O-Dibenzoyl-2'-deoxycytidine has been shown to inhibit the growth of certain strains of bacteria and can be used for the treatment of tuberculosis. This drug also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. !-- END OF PRODUCT DESCRIPTIONS --></p>Formule :C23H21N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :435.44 g/mol7-Deaza-2'-deoxyadenosine
CAS :<p>7-Deaza-2'-deoxyadenosine is an oligodeoxynucleotide analog that has been shown to be a potent inhibitor of human ovarian carcinoma cells. It inhibits the uptake of organic anion transporters, which are proteins found in the cell membrane that transport organic anions such as nucleosides and nucleotides. 7-Deaza-2'-deoxyadenosine has also been shown to inhibit DNA synthesis and polymerase chain reactions by binding to the enzyme RNA polymerase II. This drug can be synthesized with solid phase chemistry, making it a highly reproducible product.</p>Formule :C11H14N4O3Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :250.26 g/molNicotinic acid riboside
CAS :<p>Nicotinic acid riboside is a nicotinic acid derivative that has been shown to increase NAD+ levels in cells. Nicotinic acid riboside has been shown to increase the activity of enzymes involved in energy metabolism and transfer reactions, as well as target enzymes such as nicotinamide phosphoribosyltransferase (NAMPT) and its substrate, nicotinamide mononucleotide (NMN). It also increases cellular NAD+ levels by inhibiting the degradative enzyme, nicotinamide phosphoribosyltransferase (NAMPT). Nicotinic acid riboside can be used to treat metabolic disorders such as diabetes mellitus type 2.</p>Formule :C11H13NO6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :255.22 g/mol5'-O-Benzoyl-2,3'-anhydrothymidine
CAS :<p>5'-O-Benzoyl-2,3'-anhydrothymidine is a heterocycle that has been shown to have immunosuppressive properties. The compound binds to the immunodeficiency virus by covalent binding to an isomeric site on the viral envelope protein. It has been shown that 5'-O-Benzoyl-2,3'-anhydrothymidine can inhibit the growth of HIV in vitro with a 50% inhibitory concentration (IC50) of 0.8 μM. This compound also displays potent antiviral activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2).</p>Formule :C17H18N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :330.34 g/mol7-(N-Acetylaminomethyl)-7-deazaguanosine
<p>7-(N-Acetylaminomethyl)-7-deazaguanosine is a nucleoside analog that is used to treat diseases such as hepatitis B and C. It is an antiviral, anticancer, and antibacterial agent. 7-(N-Acetylaminomethyl)-7-deazaguanosine inhibits viral replication by blocking the synthesis of DNA or RNA. The drug also inhibits cell growth through activation of apoptosis, which may be due to its ability to inhibit protein synthesis and DNA replication. This novel nucleoside analog has shown high purity levels in our lab and can be used for the treatment of various diseases.</p>Formule :C14H19N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :353.33 g/mol3-Acetylpyridine adenine dinucleotide
CAS :<p>A non-physiological analog of nicotinamide adenine dinucleotide (NAD+) in biochemical research, particularly as a tool to study the mechanisms of NAD+-dependent enzymes.</p>Formule :C22H28N6O14P2Degré de pureté :Min. 92 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :662.44 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt
CAS :<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-O-succinate triethylammonium salt is a novel nucleoside analog that has antiviral and anticancer properties. It is a ribonucleotide with an N6-(benzoyl)-2'-deoxyadenosine base linked to the 3' position of the sugar through an acetyl group, with a succinic acid moiety at the 5' position. This drug inhibits DNA synthesis and has been shown to block HIV replication in vitro. It also has activity against human papillomavirus type 16 (HPV16) infections in vivo.</p>Formule :C42H39N5O9·C6H15NDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :858.98 g/molN6-Succinyl adenosine
CAS :<p>N6-Succinyl adenosine is a biochemical that is involved in the transfer of fatty acids across membranes. It has been shown to be effective in transfection experiments, where it can be used to increase the expression of genes. N6-Succinyl adenosine has also been shown to be an important substrate for various dehydrogenases. Deficiency of these enzymes leads to orotic aciduria, which is characterized by elevated levels of orotic acid in blood and urine and may lead to mental retardation. A linear calibration curve was generated for diagnosis purposes, with the enzyme activities being determined using a logistic regression model.</p>Formule :C14H17N5O8Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :383.31 g/mol2’-Deoxy-N1-methylguanosine
CAS :Produit contrôlé<p>2’-Deoxy-N1-methylguanosine is a modified purine nucleoside composed of a N¹-methylguanine, a guanine base where a methyl group is attached to the nitrogen at position 1 (N¹). This methylation blocks normal Watson-Crick base pairing, especially with cytosine, and can affect RNA structure and function. It also contains a 2′-Deoxyribose and has possible research applications</p>Formule :C11H15N5O4Degré de pureté :Min. 97 Area-%Couleur et forme :PowderMasse moléculaire :281.27 g/molb-Nicotinamide adenine dinucleotide reduced form, disodium salt
CAS :<p>β-Nicotinamide adenine dinucleotide reduced form, most commonly known as NADH, is a cofactor involved in the electron transport chain, in the metabolism of amino acids and many other cellular processes such as the synthesis of ATP. It is also a substrate for glutathione peroxidase and superoxide dismutase. The reduced form of NADH can be used as an indicator for glutathione peroxidase activity. In addition, it has been shown to have antioxidant properties by reducing reactive oxygen species (ROS) and inhibiting lipid peroxidation. This product has been used in formulations of synthetic drugs for the treatment of women with long-term effects of menopause, such as osteoporosis and cardiovascular disease. It has also been used in the production of alginate gel, which can be used to create scaffolds for tissue engineering applications. More recently, in bioorganic chemistry, NADH has been used as a source of hydride species for reduction reactions.</p>Formule :C21H27N7O14P2·2NaDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :709.4 g/molN4-Acetyl-5'-O-DMT-cytidine
CAS :<p>N4-Acetyl-5'-O-DMT-cytidine is an antiviral drug that inhibits the viral DNA polymerase. It is a modified nucleoside, which is activated by phosphorylation. N4-Acetyl-5'-O-DMT-cytidine is used in research for its anticancer properties and has shown to inhibit the growth of cancer cells in vitro. The compound was found to be more potent than cytidine and other modified nucleosides.</p>Formule :C32H33N3O8Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :587.63 g/molCytarabine
CAS :<p>Anti-viral; anti-neoplastic</p>Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :243.22 g/mol2-Deoxy-5-vinyluridine
CAS :<p>2-Deoxy-5-vinyluridine (5-VUdR) is a chemical compound that has been shown to cause a mutation in the DNA of herpes simplex virus. The compound is then incorporated into the viral DNA and replicated with each new cell division, leading to mutations in the sequence of its genome. This mutation can either be lethal or nonlethal, depending on how it affects the function of the virus. 5-VUdR has also been shown to affect cancer cells by inhibiting their growth and causing them to undergo apoptosis. This chemical compound also has an effect on animals and humans, as it alters body mass index and causes weight loss. It does this by preventing replication of DNA in cells that produce insulin, which leads to low insulin levels and decreased appetite.END></p>Formule :C11H14N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :254.24 g/molN6-Benzyladenosine
CAS :<p>N6-Benzyladenosine is a nucleoside that is synthesized from adenosine and benzylamine. It is a component of the nutrient solution for cell culture studies, which has been shown to have an effect on the hydrophobic effect in cells. This compound also acts as a co-factor for epidermal growth factor and enzyme activities. N6-Benzyladenosine has been used in the development of monoclonal antibodies with covalent linkages. It is also being studied as a potential biomarker for various cancers, including prostate cancer and other solid tumors. In addition, this compound has been shown to be a sesquiterpene lactone with structural analysis and pharmacokinetic properties. N6-Benzyladenosine can be found in plants such as tomato and ginger at physiological levels.</p>Formule :C17H19N5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :357.36 g/molN6-Benzoyl-2'-deoxy-8-oxoadenosine
CAS :<p>N6-Benzoyl-2'-deoxy-8-oxoadenosine is a base modified deoxy nucleoside</p>Formule :C17H17N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :371.35 g/mol5'-Azido-5'-deoxyadenosine
CAS :<p>5'-Azido-5'-deoxyadenosine (Aza-dA) is an adenosine analog that inhibits the deamination of S-adenosylhomocysteine to form adenosine. It has been shown to be more potent than 2-chloroadenosine and inactivates the enzyme s-adenosylhomocysteine hydrolase, which is responsible for the conversion of S-adenosylhomocysteine to adenosine. This leads to decreased levels of adenosine and increased levels of s-adensoylhomocysteine. Aza-dA has been shown to inhibit tumor growth and induce apoptosis in rat hepatocytes. In addition, it is a halogenated molecule that can be used as a modifying agent.</p>Formule :C10H12N8O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :292.25 g/molN6-Acetyl-2',3',5'-tri-O-acetyl-8-hydroxyadenosine
<p>N6-Acetyl-2',3',5'-tri-O-acetyl-8-hydroxyadenosine is a modified nucleoside that is used in the synthesis of oligonucleotides. It is an activator with antiviral and anticancer properties, as well as various other biological activities. The CAS number for this product is 91359-02-2. The purity of this product ranges from 99% to 100%. This chemical has not been previously synthesized and has not been modified by any substituents or moieties.</p>Formule :C18H21N5O9Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :451.39 g/molN6-Benzoyl-3',5'-O-(1,1,3,3- tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS :<p>N6-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine is a novel antiviral agent that belongs to the class of nucleoside analogues. It has high antiviral activity against human cytomegalovirus and herpes simplex virus type 1. N6-Benzoyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine also has anticancer effects and is used in the treatment of leukemia. This drug inhibits DNA synthesis by acting as a competitive inhibitor for deoxyribonucleotide triphosphates and binds to ribonucleosides in order to inhibit DNA replication.</p>Formule :C29H43N5O6Si2Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :613.87 g/molN4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine
CAS :<p>N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is a novel nucleoside that was synthesized by converting the ribonucleoside 5'-O-DMT to its deoxyribonucleoside form. N4-Benzoyl-5'-O-DMT-2'-O-propargyl adenosine is an antiviral and antiproliferative agent that inhibits DNA synthesis. It also has anticancer activity, but does not have any effect on RNA synthesis. This product is available in high quality and high purity with CAS No. 171486-51-4.</p>Formule :C41H37N5O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :711.76 g/mol3'-Amino-3'-deoxyuridine
CAS :<p>3'-Amino-3'-deoxyuridine is a nucleoside that is phosphoramidated to the 3' hydroxyl group of uridine. It has been shown to be detectable experimentally and has regiospecificity. The imidazole ring has been shown to be acidic, making it an excellent candidate for kinetics studies. 3'-Amino-3'-deoxyuridine is activated by cleavage of its phosphodiester bond by nucleophilic attack. This nucleotide can be used in the research of nucleic acids and imidazole derivatives.</p>Formule :C9H13N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :243.22 g/mol6-Azacytosine
CAS :<p>Nucleoside analogue; anti-viral; anti-tumoral agent</p>Formule :C3H4N4ODegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :112.09 g/mol3'-O-Benzoylthymidine
CAS :<p>3'-O-Benzoylthymidine is a nucleoside that is used in the synthesis of DNA. It is a monomeric compound that contains two deoxyribose sugars and one deoxyribonucleotide. 3'-O-Benzoylthymidine interacts with the phosphite triester, which stabilizes the nucleobase. This reaction leads to the formation of a glycosidic bond between the phosphate group and the 5' carbon atom in the sugar ring of 3'-O-benzoylthymidine. The chloride ion is then added to form an intermediate compound with a reactive electrophilic carbon center that can be used for subsequent reactions with other compounds or nucleobases. 3'-O-Benzoylthymidine can also be conjugated to other compounds through covalent bonds, such as phosphonates, to form more complex molecules.</p>Formule :C17H18N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :346.34 g/molUDP-N-azidoacetylgalactosamine triethylamine
CAS :<p>UDP-N-azidoacetylgalactosamine (UDP-GlcNAz) is an analogue of UDP-GalNAc, bearing an azido group on the N-acyl side chain. It acts as an unnatural substrate for the polypeptide N-R-acetylgalactosaminyltransferases (ppGalNAcTs) which are enzymes that play a role in mucin-type O-linked glycoprotein biosynthesis. UDP-GlcNAz is accepted as a nucleotide-sugar donor, appending an azidosugar onto its native substrates, which can then be detected using azide-reactive chemical probes. The azide group can be detected by the conjugation with phosphine probes via the Staudinger ligation, or alkyne probes via cycloaddition reactions.</p>Formule :C17H26N6O17P2Degré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :848.73 g/molAdenosine 5′-phosphosulfate sodium salt
CAS :<p>Adenosine 5′-phosphosulfate sodium salt has been used quantify pyrophosphate and in enzyme-linked bioluminescence assay for adenosine triphosphate (ATP)</p>Formule :C10H14N5O10PSDegré de pureté :Min. 90 Area-%Couleur et forme :PowderMasse moléculaire :427.29 g/molAdenosine - Endotoxin level below 1000 EU/g
CAS :<p>Adenosine is a naturally-occurring organic solvent found in the human body. It has been shown to inhibit fibroid growth and to have an anti-inflammatory effect on the uterus. Adenosine is also a potent endogenous vasodilator, which may be due to its ability to activate adenosine receptors. In addition, it has been demonstrated that adenosine inhibits the synthesis of target enzymes such as collagenase and hyaluronidase. The uptake of adenosine by cells is inhibited by nevirapine, which is an HIV protease inhibitor. This inhibition leads to increased extracellular levels of adenosine, which stimulates phosphorylation of extracellular-regulated kinases (ERKs) and decreases histamine release from mast cells. The ERKs are activated in response to many stimuli including cytokines, growth factors, and stressors such as UV light or heat shock.BR><br>In vitro studies using human tissue have shown that ad</p>Formule :C10H13N5O4Degré de pureté :(Titration) 99.0 To 101.0%Couleur et forme :White Off-White PowderMasse moléculaire :267.24 g/mol4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine ammonium
CAS :<p>The 4-Amino-6-hydroxy-2-mercapto-5-nitrosopyrimidine ammonium salt is a solvent that has been used in the synthesis of various organic and inorganic compounds. It is a five membered ring compound with solvents, such as chlorides, and it can be found in diffraction patterns. 4-Amino-6-hydroxy-2-mercapto-5 nitrosopyrimidine ammonium salt can also act as a ligand in metal complexes. The molecule has carbonyl groups which chelate to the metal atom and form a ring with chlorine atoms.</p>Formule :C4H4N4O2S•NH3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :189.2 g/mol6-Chloro-9-(2'-deoxy-β-D-ribofuranosyl)purine
CAS :<p>6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a nucleoside analogue that inhibits the replication of the hepatitis C virus. It binds to the viral RNA polymerase and blocks the synthesis of viral RNA, thereby preventing infection. This drug also has antiviral activity against HIV and herpes simplex viruses. The antiviral effect is due to its ability to inhibit phosphatases and carboxylates, which are involved in the initiation of mRNA transcription and protein translation, respectively. 6-Chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is metabolized by deoxyadenosine kinase into 6-chloropurine ribonucleotide, which can be converted into other purines.</p>Formule :C10H11ClN4O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :270.68 g/molThymidine-5'-monophosphate disodium salt
CAS :<p>Thymidine-5'-monophosphate disodium salt is a nucleoside that is synthesized by reductive phosphorylation of thymidine. It is a substrate for nucleotide synthesis and can be used as a reagent in the synthesis of oligonucleotides. Thymidine-5'-monophosphate disodium salt can be reduced to form thymidine, which can then be converted to 5-thio-2'-deoxyuridylate or 5-thio-2'-deoxycytidylate. This conversion takes place through the cleavage reaction of the thymidine residue from the disodium salt.</p>Formule :C10H13N2Na2O8PDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :366.17 g/mol9-(b-D-Arabinofuranosyl)guanine
CAS :<p>9-(b-D-Arabinofuranosyl)guanine is an arabinoside derivative that has high affinity for DNA. 9-(b-D-Arabinofuranosyl)guanine binds to the phosphate groups in DNA and inhibits the synthesis of DNA. It is used in vitro assays to study molecular pathogenesis and in vivo as a drug against leukemia, lymphomas, and other cancers. 9-(b-D-Arabinofuranosyl)guanine also inhibits protein synthesis by binding to ribosomes. This drug can cause significant side effects such as gastrointestinal distress, diarrhea, nausea, vomiting, and abdominal pain. It can also cause blood dyscrasias and liver damage.</p>Formule :C10H13N5O5Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :283.24 g/molN6-Acetyladenosine
CAS :<p>N6-Acetyladenosine is a nucleoside that belongs to the group of N-acetylated adenosines. It is found in thermophilic organisms and has been shown to be involved in optimal growth. N6-Acetyladenosine has also been found to be an important part of the coding and population modifications of crenarchaeota, archaeal organisms that are phylogenetically related to methanogens. Unfractionated populations of methanogen contain both N6-acetyladenosine residues and other modified adenosines, with each organism differing in the types of modifications they contain. Transfer of these modified adenosines from one organism to another can lead to changes in their coding and population modifications.</p>Formule :C12H15N5O5Degré de pureté :Area-% Min. 90 Area-%Couleur et forme :White PowderMasse moléculaire :309.28 g/mol2',3'-O-Isopropylideneuridine
CAS :<p>2′,3′-O-Isopropylideneuridine serves as a key intermediate in the chemical synthesis of N-benzoyl uridine derivatives and N3-substituted 2′,3′-O-isopropylideneuridines, which exhibit central nervous system (CNS) depressant properties</p>Formule :C12H16N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :284.27 g/mol2'-Deoxy-5-formyluridine
CAS :<p>2'-Deoxy-5-formyluridine (2DFO) is a nucleobase analogue that inhibits the enzymatic activity of DNA glycosylases, which are enzymes that remove sugar residues from damaged DNA. 2DFO has been shown to induce apoptosis in cancer cells by inhibiting DNA synthesis and promoting oxidative damage to the cell's DNA. 2DFO has also been shown to inhibit the growth of DU-145 cells in vitro and in vivo models. This drug was found to be more effective at preventing metastasis of colorectal cancer when it was administered with a platinum-based chemotherapy drug.</p>Formule :C10H12N2O6Degré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :256.21 g/mol2'-Deoxy-L-guanosine
CAS :<p>2'-Deoxy-L-guanosine is a nucleoside that is used as an antibiotic. It inhibits protein synthesis, which leads to cell death. This drug has a high level of resistance against bacteria and is effective in the treatment of gram-positive bacteria. 2'-Deoxy-L-guanosine binds to the ribose phosphate backbone of DNA, phosphorylating it and preventing the base pairing of adenosine with thymine. This inhibits the production of DNA and RNA, leading to cell death. 2'-Deoxy-L-guanosine has been shown to be active against Listeria monocytogenes and Mycobacterium tuberculosis. The enantiomer form is more potent than the racemic mixture, but both forms are effective antibiotics.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :267.25 g/molS-Adenosyl-L-methionine p-toluenesulfonate
CAS :<p>Methyl donor and a cofactor for enzyme-catalyzed methylations</p>Formule :C15H23N6O5S•C7H7O3SDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :570.64 g/mol5-(2-Amino-2-oxoethyl)-2-thiouridine
CAS :<p>5-(2-Amino-2-oxoethyl)-2-thiouridine is a modified deoxyribonucleoside that is used as a phosphoramidite to synthesize oligonucleotides. 5-(2-Amino-2-oxoethyl)-2-thiouridine inhibits the synthesis of viral DNA and RNA, and its antiviral activity has been shown in vitro. It also may have anticancer activity due to its ability to inhibit DNA synthesis and cell proliferation. This compound has high quality, high purity, and novel properties.</p>Formule :C11H15N3O6SDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :317.32 g/mol5-Bromocytidine
CAS :<p>5-Bromocytidine is a pyrimidine nucleoside that has been shown to inhibit the replication of influenza virus in cell culture. It stabilizes the ribonucleotide reductase enzyme, which is responsible for converting ribonucleosides to deoxyribonucleosides. This inhibition prevents the production of viral RNA and protein synthesis, leading to inhibition of viral growth. 5-Bromocytidine has also been shown to have antiviral effects against HIV and herpes simplex virus type 1 (HSV1) in cell cultures.</p>Formule :C9H12BrN3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :322.11 g/molN4-Aminocytidine
CAS :<p>N4-Aminocytidine is an analog of uridine that can be used as an inhibitor of the growth of bacteria. It has been shown to inhibit the growth of Escherichia coli and Salmonella typhimurium in vitro. N4-Aminocytidine binds to the bacterial ribosome and inhibits protein synthesis, which results in cell death. This drug has also been found to act as a potent synthetic cannabinoid receptor agonist in vivo and inhibits uptake of cannabinoids into cells in culture. N4-Aminocytidine has also been shown to bind to dna duplexes and chemically react with them, altering their structure. This drug has not yet been tested for safety or efficacy in humans.</p>Formule :C9H14N4O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :258.23 g/mol1,3-Dimethylpseudouridine
CAS :<p>1,3-Dimethylpseudouridine is a methylated derivative of pseudouridine, which is a naturally occurring modified nucleoside found in RNA. This compounds can be used in research applications</p>Formule :C11H16N2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :272.25 g/mol3'-O-Aminothymidine
CAS :<p>3'-O-Aminothymidine is an isomer of thymidine, a nucleoside that is found in DNA and RNA. It has a neutral charge and belongs to the category of nucleosides. 3'-O-Aminothymidine is synthesized by the coupling of an amino group with a hydroxyl group. This reaction is efficient and can be used to produce dimers. 3'-O-Aminothymidine can also be used as a precursor for other nucleotides or as a synthetic intermediate in other chemical reactions.</p>Formule :C10H15N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :257.24 g/molStearoyl coenzyme A lithium
CAS :<p>Stearoyl coenzyme A lithium is a novel modified ribonucleoside that is synthesized by enzymatic phosphorylation of 3'-deoxyribonucleosides. It has anticancer, antiviral, and antitumor activities. Stearoyl coenzyme A lithium is a monophosphate nucleotide which activates the transcription factors that regulate gene expression and replication. The drug also inhibits viral replication through competitive inhibition of the viral DNA polymerase.</p>Formule :C39H70N7O17P3S·xLiDegré de pureté :90%Couleur et forme :PowderMasse moléculaire :1,034 g/mol8-Bromoguanosine
CAS :<p>8-Bromoguanosine (8BrG) is a potent inhibitor of cyclase enzymes that lead to the formation of cyclic guanosine monophosphate (cGMP). It has been shown to inhibit signal pathways, such as those regulated by the G protein-coupled receptor (GPCR), which are activated by the 2-adrenergic receptor. 8BrG has been shown to be effective against C. glabrata and other fungi and has been used in experimental models for infectious diseases.</p>Formule :C10H12BrN5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :362.14 g/mol2'-Deoxy-N2-isobutyrylguanosine
CAS :<p>2'-Deoxy-N2-isobutyrylguanosine (2'-DIBG) is an inhibitor of bacterial translocation that has been shown to inhibit the growth of several bacterial species. This drug binds to fatty acids, which are important for maintaining the integrity of the cell membrane and preventing bacterial translocation. 2'-DIBG also inhibits the production of reactive oxygen species by bacteria, which contributes to its antimicrobial activity. Inflammation can be reduced by inhibiting prostaglandin synthesis with 2'-DIBG. The inhibition of prostaglandin synthesis may be due to its ability to form acid conjugates with fatty acids and dicarboxylic acids, which are precursors for prostaglandins. 2'-DIBG also inhibits the synthesis of adenosine triphosphate (ATP) in bacteria, leading to a decrease in bacterial growth rate.</p>Formule :C14H19N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :337.34 g/mol5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose 5'-monophosphate
CAS :Produit contrôlé<p>5-Aminoimidazole-4-carboxamide-1-b-D-ribofuranose 5'-monophosphate (AICAR) is an analogue of AMP that activates the AMPK pathway. It is a potent activator that increases the activity of this enzyme, which regulates cellular energy metabolism. AICAR has been shown to induce significant cytotoxicity in k562 cells and to increase the levels of ATP in these cells. This compound has also been shown to have potential use in metabolic disorders, such as type 2 diabetes, by increasing uptake and kinetic of glucose. AICAR has also been shown to activate the AMPK pathway in prostate cancer cells and increase cellular physiology.</p>Formule :C9H15N4O8PDegré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :338.21 g/molMizoribine
CAS :<p>Inhibitor of heat shock protein Hsp60; immunosuppressant</p>Formule :C9H13N3O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :259.22 g/mol2'-Deoxy-5-hydroxymethyluridine
CAS :<p>2'-Deoxy-5-hydroxymethyluridine (DHMU) is a natural compound that has been shown to have inhibitory properties against bowel disease. DHMU inhibits the proliferation of wild-type strains of Salmonella enterica serovar Typhimurium and Escherichia coli by binding to their nuclear dna. It also prevents DNA synthesis in human polymorphonuclear leukocytes and synergizes with pharmacological agents, such as radiation or chemotherapeutic agents, to induce cell death. This agent can be used as an analytical method for the detection of nucleic acids.</p>Formule :C10H14N2O6Degré de pureté :Min. 98.0 Area-%Couleur et forme :White PowderMasse moléculaire :258.23 g/molN6-Benzoyladenosine
CAS :<p>N6-Benzoyladenosine is a purine nucleoside that is synthesized from uridine and has a high resistance to phosphorylation. It is found in the mitochondrial matrix of rat hepatocytes and can be used as a specific agent for the treatment of symptoms related to Parkinson's disease. N6-Benzoyladenosine inhibits protein synthesis by inhibiting the catalytic subunit of guanine nucleotide-binding proteins, which are involved in cellular energy production. It also inhibits camp levels and camp concentrations in mitochondria, which may be due to its effects on the trimethylbenzodiazepine receptor.</p>Formule :C17H17N5O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :371.35 g/mol8-Bromo-2'-deoxyguanosine
CAS :<p>8-Bromo-2'-deoxyguanosine is a reactive brominated compound that has been shown to stabilize DNA strands. The effects of 8-bromo-2'-deoxyguanosine on the stability of DNA are due to the steric interactions between the bromine and amines in the DNA backbone, which prevent nucleophilic attack. 8-Bromo-2'-deoxyguanosine is an antihistamine, but it has also been used as a precursor for other drugs such as zidovudine, an antiviral drug used in HIV/AIDS therapy. It has also been proposed as a potential treatment for atherosclerosis.</p>Formule :C10H12BrN5O4Degré de pureté :Min. 90 Area-%Couleur et forme :Off-White PowderMasse moléculaire :346.14 g/mol2'-C-Methyladenosine
CAS :<p>Antiviral compound; inhibitor of viral RNA replication</p>Formule :C11H15N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :281.27 g/molN4-Benzoyl-L-cytidine
CAS :<p>N4-Benzoyl-L-cytidine is an acid that is used as a building block in organic synthesis. It is a precursor to many biologically active compounds, including nucleosides and nucleotides. N4-Benzoyl-L-cytidine is an aminoacylated derivative of cytidine, which can be synthesized by reacting the benzoyl chloride with the corresponding amine. This reaction product can be purified by extraction into an organic solvent followed by washing with water and drying under vacuum. The compound can be converted to its hydrolysis products, benzoic acid and pyrrolidinone, through acidic hydrolysis. The synthesis of N4-benzoyl-L-cytidine can also be achieved using solid phase chemistry (SPS) to exploit the reactivity of amino acids and their derivatives.</p>Formule :C16H17N3O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :347.32 g/mol2'-Deoxycytidine-3'-monophosphate
CAS :<p>2'-Deoxycytidine-3'-monophosphate free acid is a nucleotide that is synthesized from deoxyadenosine triphosphate and deoxycytidine triphosphate in the presence of ribonucleotide reductase. It is the precursor to DNA synthesis, where it is converted to dCTP by thymidylate synthase. 2'-Deoxycytidine-3'-monophosphate free acid has low energy and vibrational levels, due to its glycosidic bond. This bond can be broken by chromatographic methods. The excised activated product uridine can be used for carcinogenesis studies, as well as for other molecular studies such as electron microscopy and crystallography. 2'-Deoxycytidine-3'-monophosphate free acid is an unstable molecule that can undergo dinucleotide rearrangements, electron transfer, or bond cleavage to form a metastable molecule with</p>Formule :C9H14N3O7PDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :307.2 g/molTenofovir disoproxil fumarate
CAS :<p>Anti-viral; reverse transcriptase inhibitor</p>Formule :C23H34N5O14PDegré de pureté :Min. 97.5 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :635.52 g/mol3'-Amino-2',3'-dideoxyinosine
CAS :<p>3'-Amino-2',3'-dideoxyinosine acts as a chain terminator in DNA synthesis due to the absence of a 3'-hydroxyl group. The 3'-amino group allows for the attachment of various molecules to the 3' end of oligonucleotides, and the inosine base introduces the potential for wobble base pairing, making it a specialized tool for research and potential diagnostic applications.</p>Formule :C10H13N5O3Degré de pureté :Min. 95%Masse moléculaire :251.24 g/mol2',5'-Dideoxycytidine
CAS :<p>2',5'-Dideoxycytidine is a nucleoside for use in a variety of applications</p>Formule :C9H13N3O3Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :211.22 g/mol3'-Amino-3'-deoxyguanosine
CAS :<p>terminates RNA strand synthesis catalyzed by RNA polymerase.</p>Formule :C10H14N6O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :282.3 g/mol2'-O-Allyladenosine
CAS :<p>2'-O-Allyladenosine is a synthetic nucleoside analog that has been shown to be a competitive inhibitor of the enzyme guanosine kinase. It has a high yield and can be used as a synthon for the preparation of 2'-deoxyribose nucleosides. The alkylation of allyl groups onto adenosines provides an efficient method for synthesizing allylated purines, which are analogs with increased stability and affinity for DNA sequences. 2'-O-Allyladenosine has been shown to bind to DNA, RNA, and proteins. Its interaction with DNA is stronger than that of unmodified adenosine, due to the presence of two allyl groups that can form hydrogen bonds with the phosphate backbone. This interaction may also lead to increased affinity for sequences containing G-C base pairs.</p>Formule :C13H17N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :307.31 g/mol5-Azacytidine
CAS :<p>An azanucleoside and epigenetic modulator that interferes with nucleic acid metabolism. The compound gets incorporated into RNA and inhibits ribonucleotide reductase subunit RRM2 in leukemia cell lines. Intracellularly, 5-azacytidine can get converted into 2′-deoxy-5-azacytidine (decitabine) and subsequently incorporated in DNA, where it irreversibly inhibits DNMT1 methyltransferase. In human epithelial cell lines, this compound decreases Src-activated expression of a histone chaperone CAF1 and inhibits cell motility and invasiveness.</p>Formule :C8H12N4O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :244.21 g/mol5-(Azidomethyl)uridine
CAS :<p>5-(Azidomethyl)uridine (5-AZA-U) is a cytosolic nucleoside analog that inhibits the replication of herpes simplex virus type 1 (HSV-1). It is resistant to degradation by cellular nucleases and is fluorescent, making it a clickable substrate for microscopy. 5-AZA-U has been shown to inhibit the transcription of viral DNA and the synthesis of viral proteins in mammalian cells. This drug has also been shown to be effective against cancer and hepatitis B virus (HBV). 5-AZA-U can be used as an antiviral agent because of its ability to inhibit the posttranscriptional gene expression of HSV-1. 5-(Azidomethyl)uridine is also an analog of uridine, which can be used to study intracellular signaling pathways that regulate proliferation, differentiation, or apoptosis in mammalian cells.</p>Formule :C10H13N5O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :299.24 g/molAcetyl coenzyme A lithium
CAS :<p>Acetyl coenzyme A lithium salt is a drug that inhibits the production of acetyl-CoA, which is an important molecule in the metabolism of fatty acids. This drug has been shown to be effective against cancerous cells by inhibiting the synthesis of lysine residues and carnitine. Acetyl coenzyme A lithium salt has also been shown to inhibit the growth of typhimurium, which may be due to its ability to inhibit NADPH-cytochrome p450 reductase. Acetyl coenzyme A lithium salt has not been shown to have any carcinogenic potential in humans, but it has been shown to have carcinogenic potential in animal models.</p>Formule :C23H38N7O17P3S•LixDegré de pureté :Min. 85%Couleur et forme :PowderMasse moléculaire :809.57 g/mol7-Methylguanosine 5'-triphosphate sodium
CAS :<p>7-Methylguanosine 5'-triphosphate sodium salt is a Novel, High purity, Activator, High quality, Modified, Ribonucleosides. CAS No. 104809-18-9. Synthetic, DNA, Phosphoramidites. Anticancer, diphosphate. 7-Methylguanosine 5'-triphosphate sodium salt is an antiviral agent that blocks the synthesis of viral RNA or DNA by inhibiting the enzyme ribonucleotide reductase. It is a monophosphate analog of guanosine triphosphate and may be useful in the treatment of cancer or antiviral therapy because it inhibits cell proliferation and induces apoptosis in tumor cells.</p>Formule :C11H18N5O14P3•NaxDegré de pureté :Min. 85 Area-%Couleur et forme :PowderMasse moléculaire :537.21 g/mol5'-O-Acetyladenosine
CAS :<p>5'-O-Acetyladenosine is a labile nucleoside that can be converted to adenosine. It is a substrate for the enzyme ribonucleotide reductase, which converts it to adenosine monophosphate. 5'-O-Acetyladenosine has been shown to function as an equilibrating agent in the synthesis of guanosine and other pyrimidine nucleotides. In addition, it is a precursor for the synthesis of purines. 5'-O-Acetyladenosine can be synthesized from trimethyl phosphate and chloride gas yields acetaldehyde, which then reacts with phosphorus oxychloride to form 5'-O-acetyladeninol, which undergoes hydrolysis to yield 5'-O-acetyladenosine. The regioselectivity of this reaction depends on the concentration of reactants and solvents used in the reaction.</p>Formule :C12H15N5O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :309.28 g/mol2,2'-Anhydrouridine
CAS :<p>The nucleophilic opening of 2,2'-Anhydrouridine represents a novel synthetic approach for elaborating the ring of nucleosides. For example, compounds such as 2-amino-, 2-fluoro- and 2-phenylseleno-2-deoxyuridines are prepared from the nucleophilic opening of 2,2'-Anhydrouridine.Â2,2'-Anhydrouridine inhibits uridine phosphorylase, a key enzyme targeted by some antitumor drugs.</p>Formule :C9H10N2O5Degré de pureté :Min. 98 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :226.19 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine
CAS :<p>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is a novel synthetic nucleoside with antiviral and anticancer activities. It is a phosphoramidite that can be used to synthesize oligonucleotides of any sequence. It is a nucleoside analogue that has been shown to inhibit the activity of DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is also an activator of viral transcription and replication.<br>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although it is not active against acid fast bacteria such</p>Formule :C40H39N5O8Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :717.77 g/molGuanosine hydrate
CAS :<p>Blocks glutamatergic activity; neuroprotective</p>Formule :C10H13N5O5·xH2ODegré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :283.24 g/molAdenosine 5'-monophosphate monohydrate
CAS :<p>Adenosine 5'-monophosphate monohydrate (AMP) is a nucleotide that is released by cells in response to various stimuli. It is involved in the regulation of metabolic rate, cell death, and inflammatory responses. AMP may also act as a mediator of opioid-induced analgesia. AMP has been shown to inhibit the production of pro-inflammatory cytokines in activated macrophages and to reduce nociception at high doses. This drug also has an effect on blood pressure and may be used for the treatment of hypertension.</p>Formule :C10H14N5O7P•H2ODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :365.24 g/molAllopurinol riboside
CAS :<p>Allopurinol riboside is a hydroxyl analog of allopurinol. Allopurinol riboside has minimal toxicity in tissue culture and exhibits no cytotoxicity in human serum. It is a potent inhibitor of microbial infection, including infections caused by Hepatitis C virus (HCV), Leishmania amazonensis, and Mycobacterium tuberculosis. Allopurinol riboside binds to adenine nucleotide and inhibits the synthesis of purines, which are necessary for DNA replication. This binding also inhibits the production of ATP, leading to cell death. In addition, allopurinol riboside inhibits the growth of human macrophages in vitro by inhibiting protein synthesis. Allopurinol riboside may be useful for treating HCV-induced liver disease or leishmaniasis.</p>Formule :C10H12N4O5Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :268.23 g/mol8-Aza-7-deaza-2'-deoxyadenosine
CAS :<p>8-Aza-7-deaza-2'-deoxyadenosine is a single-stranded DNA analogue that is used as a conjugate to deliver drugs to cells. It has been shown to be effective in the treatment of HIV by suppressing viral replication and the production of infectious virions. The drug is photolabile, which means it can be activated with light and then delivered to cells. 8-Aza-7-deaza-2'-deoxyadenosine has also been shown to inhibit the growth of human immunodeficiency virus (HIV) in vitro, but does not inhibit the growth of other viruses such as herpes simplex virus type 1 or adenovirus.</p>Formule :C10H13N5O3Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :251.24 g/mol2,2'-Anhydrothymidine
CAS :<p>2,2'-Anhydrothymidine is an anhydro version of thymidine. As 2,2'-Anhydrothymidine is a modified version of thymidine it can help researchers understand what happens when DNA is changed or damaged. Other possible uses as in research related to antiviral drug creation.</p>Formule :C10H12N2O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :240.21 g/mola-Adenosine
CAS :<p>a-Adenosine is a nucleoside that has been shown to have anti-cancer properties. It inhibits the proliferation of squamous carcinoma cells by irreversibly inhibiting adenosine deaminase, which converts adenosine to inosine, as well as other enzymes such as DNA polymerase and ribonucleotide reductase. The reaction mechanism for this inhibition is not yet fully understood, but it may be related to the inhibition of camp levels or receptor activity. a-Adenosine has also been shown to have anti-microbial properties against bacteria, fungi and yeast. It inhibits the growth of these microorganisms by binding to their cell walls and preventing protein synthesis. This drug is rapidly hydrolyzed in vivo and has an antimicrobial effect at physiological concentrations.<br>A more potent analog of a-adenosine (a-adenosinium) has been developed that can inhibit epidermal growth factor (EGF).</p>Formule :C10H13N5O4Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :267.24 g/mol2'-O-Allyluridine
CAS :<p>2'-O-Allyluridine is a nucleoside analogue that contains a 2'-hydroxyl group and an allyl group. It is synthesized from the nucleoside uridine by the process of allylation. The regiospecificity of the allylation reaction has been analysed and it has been found that the amino function on the uridine reacts with an allylic hydrogen bond to form 2'-O-allyluridine. The synthesis of 2'-O-allyluridine was successful in laboratory conditions, but not under physiological conditions. Research into this compound is still ongoing as it may have potential applications in the treatment of various diseases, such as cancer.</p>Formule :C12H16N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :284.27 g/mol2,2'-Anhydro-L-uridine
CAS :<p>2,2'-Anhydro-L-uridine is a nucleoside used in for research purposes. It is of particular interest due to it being an L-isomer which is different from the D-form sugars used by the human body. It is useful to study these kinds of molecules for their use in medicine, especially as antivirals</p>Formule :C9H10N2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :226.19 g/mol2'-Deoxyguanosine monohydrate
CAS :<p>2'-Deoxyguanosine monohydrate is a nucleoside that has been shown to inhibit the synthesis of DNA in human cells. It has also been shown to have a role in the regulation of energy metabolism and mitochondrial functions. 2'-Deoxyguanosine monohydrate binds to the enzyme polymerase chain reaction, which prevents the reverse transcription process from occurring. This nucleoside is involved in the biological studies of cytokine production, such as IL-2 receptor binding and calcium pantothenate-dependent activation of nuclear DNA replication.</p>Formule :C10H13N5O4·H2ODegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :285.26 g/mol8-azido-ATP sodium salt - 10mM aqueous solution
CAS :<p>8-Azidoadenosine 3',5'-cyclic monophosphosphate is used for nucleotide labelling via a click reaction involving the azide moiety and a terminal alkyne conjugated to a label. The reaction generates a stable nucleotide labelled adduct containing a triazole link.</p>Formule :C10H12N8O13P3·Na3Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :614.14 g/mol3'-Amino-2',3'-dideoxyadenosine
CAS :<p>3'-Amino-2',3'-dideoxyadenosine's lack of a 3'-hydroxyl group makes it a chain terminator for DNA polymerase, a key application in Sanger sequencing. Additionally, the 3'-amino group serves as a functional handle for modifying the 3' end of oligonucleotides with various labels or conjugates, expanding their utility in research and diagnostics.</p>Formule :C10H14N6O2Degré de pureté :Min. 98.0 Area-%Couleur et forme :White PowderMasse moléculaire :250.26 g/mol3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine
CAS :<p>3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine is a deoxyribonucleoside that is chemically modified to be resistant to nucleases. It is used as an antiviral agent and activates the immune system by inducing cytokines, chemokines, and interferons. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-N2-isobutyrylguanosine has been shown to have antidepressant effects in mice and rats. This drug also has been shown to inhibit the production of HIV viral particles in vitro.</p>Formule :C41H51N5O8SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :769.96 g/mol2'-Deoxy-8-oxoguanosine
CAS :<p>2'-Deoxy-8-oxoguanosine (8-OHdG) is a product of oxidative DNA damage. The presence of 8-OHdG in urine has been used to detect and measure the degree of oxidative DNA damage in humans and animals, which may be linked to cancer and aging. When 8-OHdG is excreted into urine, it can react with other molecules such as protein or inorganic phosphorus, causing more oxidative DNA damage. 2'-Deoxy-8-oxoguanosine has also been shown to cause cell toxicity by damaging the cell's squamous epithelium, leading to cancer.For the 15N5 labelled version please check ND09970.</p>Formule :C10H13N5O5Degré de pureté :Min. 95 Area-%Couleur et forme :White PowderMasse moléculaire :283.25 g/mol1-(2’-Deoxy-2’-fluoro-arabinofuranosyl)-5-hydroxymethyluracil
CAS :<p>1-(2’-Deoxy-2’-fluoro-arabinofuranosyl)-5-hydroxymethyluracil (also abbreviated as FMAU-OH) is a modified nucleoside analog. It consists of a fluorinated sugar moiety (2’-deoxy-2’-fluoro-arabinofuranose) attached to a uracil base with a hydroxymethyl (-CH₂OH) group at the 5-position. The 2’-fluoro substitution and arabinose sugar configuration can enhance its stability and affect its incorporation into DNA or RNA. It has the potential to be used as an inhibitor of viral polymerases and can be used in research.</p>Formule :C10H13FN2O6Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :276.22 g/mol5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine
<p>5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine is a novel nucleoside that can be used as an antiviral and anticancer agent. It has shown to be more potent than other nucleosides in inhibiting the synthesis of viral DNA and RNA, which makes it a potential candidate for treating HIV infection and cancer. This drug can also act as an activator by stimulating the production of deoxyribonucleotides and ribonucleotides. 5'-O-Acetyl-2'-deoxy-2',2'-difluorocytidine has been shown to have high purity and quality, making it a good candidate for use in various fields of research.</p>Formule :C11H13F2N3O5Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :305.23 g/molIsoguanosine hydrate
CAS :<p>An isomer of guanosine, used as a synthesis intermediate.</p>Formule :C10H13N5O5·xH2ODegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :283.24 g/mol2'-Deoxyadenosine-5'-monophosphate free acid
CAS :<p>2'-Deoxyadenosine-5'-monophosphate free acid (2DAMP) is a nucleoside analogue that can be used as a fluorescent probe for detecting water vapor. 2DAMP has been shown to have cytotoxic activity against solid tumours in vitro, and may act by hydrogen bonding interactions with the active site of the enzyme form. 2DAMP is also an important cofactor in the polymerase chain reaction, and can inhibit cellular proliferation by inhibiting nuclear DNA synthesis. This drug has been used as an active antiretroviral therapy, where it inhibits HIV-1 reverse transcriptase. 2DAMP's mechanism of action involves the inhibition of p-nitrophenyl phosphate reductase (PNPPR), which is responsible for converting p-nitrophenyl phosphate into p-nitrophenol.</p>Formule :C10H14N5O6PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :331.23 g/molN6-Isopentenyladenosine-5'-monophosphate disodium
CAS :<p>N6-Isopentenyladenosine-5'-monophosphate sodium salt is an adenosine conjugate acid. It is a monomer of polyribonucleotide chain, which is necessary for the formation of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). N6-Isopentenyladenosine-5'-monophosphate sodium salt is a conjugate base that has the ability to bind to DNA. This binding prevents the formation of a complex with RNA polymerase, thereby inhibiting transcription and replication.</p>Formule :C15H22N5O7P•Na2Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :461.32 g/molAdenosine 3',5'-cyclic monophosphate
CAS :<p>Second messenger in intracellular signal transduction</p>Formule :C10H12N5O6PDegré de pureté :(%) Min. 95%Couleur et forme :White PowderMasse moléculaire :329.21 g/molClevudine
CAS :<p>Clevudine is a synthetic pyrimidine analogue effective against the hepatitis B virus (HBV). Once inside the cell, it is converted into its active forms, clevudine monophosphate and clevudine triphosphate. The triphosphate form competes with thymidine to be incorporated into viral DNA, leading to DNA chain termination and inhibition of the HBV DNA polymerase (reverse transcriptase). Due to its long half-life, clevudine significantly reduces covalently closed circular DNA (cccDNA), making relapse less likely after treatment ends.</p>Formule :C10H13FN2O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :260.22 g/mol9-(b-D-Arabinofuranosyl)hypoxanthine
CAS :<p>9-(b-D-Arabinofuranosyl)hypoxanthine is a glycosylated analogue of the incretin hormone glucagon-like peptide-1 (GLP-1). It has been shown to inhibit Streptococcus pyogenes and other bacteria. 9-(b-D-Arabinofuranosyl)hypoxanthine has also been shown to have inhibitory properties against zirconium oxide, pulmonary vasodilation, squamous cell carcinoma, and rate constant. This drug has not been studied in clinical trials for antiviral prophylaxis or arabinoside. The only known side effects are drug interactions with cyclin D2 and nitrate reductase.</p>Formule :C10H12N4O5Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :268.23 g/mol2'-O-Methylpseudouridine
CAS :<p>2'-O-methylpseudouridine is a modified nucleoside that belongs to the group of modified nucleosides. It is found in ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). 2'-O-methylpseudouridine is a derivative of pseudouridine and can be categorized as a modified nucleotide. The chemical structure of this compound has been shown using reversed-phase high-performance liquid chromatography. This technique can help identify modifications in RNA, such as 5-carbamoylmethyluridine. 2'-O-methylpseudouridine is an epigenetic marker that may be used to study tissues or sequences.</p>Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :258.23 g/mol5-Methylcytidine
CAS :<p>5-Methylcytidine is a nucleoside that is found in DNA and RNA. It is used in structural biology to probe the structure of DNA. 5-Methylcytidine binds to the enzyme methyl transferase, which catalyzes the transfer of a methyl group from S-adenosylmethionine to produce 5-methyluridine. This reaction occurs in long-term toxicity studies using primary cells, such as lymphocytes and fibroblasts. 5-Methylcytidine has been shown to inhibit tumour growth in mice by binding to nuclear dna polymerase and blocking transcription. The binding site for this drug on the polymerase is located at the same site as that for nucleoside analogues like azidothymidine (AZT) and zidovudine (AZT).</p>Formule :C10H15N3O5Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :257.24 g/mol2'-O-(2-Methoxyethyl)uridine
CAS :<p>2'-O-(2-Methoxyethyl)uridine is a nucleoside analog that inhibits the synthesis of DNA, RNA and protein. It can be used as an antimetabolite to treat cancer and prevents tumor growth by interfering with cell division. 2'-O-(2-Methoxyethyl)uridine is often used in combination with other chemotherapeutic drugs. This drug is not active against bacteria and does not inhibit the growth of bacteria. The major disadvantage of this drug is its lack of efficacy against tumors, which may be due to the lack of penetration through the cell membrane or damage to DNA caused by radiation, abiotic factors, or malfunctioning enzymes. 2'-O-(2-Methoxyethyl)uridine has been shown to cause damage to cells by altering their metabolism and affecting the function of their mitochondria. Damage can cause cells to die through apoptosis or necrosis.</p>Formule :C12H18N2O7Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :302.28 g/mol8-Bromocyclic adenosine diphosphate ribose sodium
CAS :<p>8-Bromocyclic adenosine diphosphate ribose sodium salt (8BCAR) is a cytosolic cyclase inhibitor that inhibits the synthesis of cyclic adenosine monophosphate (cAMP). 8BCAR blocks the activation of protein kinase A, which is an enzyme involved in the phosphorylation of cAMP. 8BCAR has been shown to inhibit cardiac hypertrophy induced by growth factor-β1 and to increase mitochondrial membrane potential, as well as to suppress cardiomyocyte apoptosis. In addition, this drug can be used for the treatment of cancers such as leukemia and lymphoma.</p>Formule :C15H19BrN5NaO13P2Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :642.19 g/mol2',5'-Dideoxyguanosine
CAS :<p>2',5'-Dideoxyguanosine is a modified nucleoside analog of guanosine, one of the four natural nucleosides found in RNA and DNA. This synthetic molecule has hydroxyl groups removed from the 2' and 5' positions of the sugar component, which alters its ability to participate in nucleic acid synthesis.</p>Formule :C10H13N5O3Degré de pureté :Min. 97 Area-%Couleur et forme :White PowderMasse moléculaire :251.25 g/molGemcitabine HCl
CAS :<p>Anticancer nucleoside; DNA synthesis interference</p>Formule :C9H11F2N3O4·HClDegré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :299.66 g/mol1-(b-D-Arabinofuranosyl)uracil
CAS :<p>1-(b-D-Arabinofuranosyl)uracil is a nucleoside analog containing uracil, a nitrogenous base found in RNA, and a β-D-Arabinofuranose sugar. This compound could be used to study its effects on DNA/RNA synthesis.</p>Formule :C9H12N2O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :244.2 g/mol2'-O-Methyl-5-methylcytidine
CAS :<p>2'-O-Methyl-5-methylcytidine is a nucleoside that is categorized as a modified nucleic acid. It is structurally similar to cytidine, but has an additional methyl group. 2'-O-Methyl-5-methylcytidine stabilizes the conformational structure of nucleic acids and can be used to regulate the activity of enzymes. This modified nucleoside has been shown to have thermophilic characteristics when it interacts with human cells. The stability of 2'-O-Methyl-5-methylcytidine increases with increasing temperature, making it possible for this molecule to regulate gene expression in organisms that live at high temperatures.</p>Formule :C11H17N3O5Degré de pureté :Min. 95%Couleur et forme :White Off-White PowderMasse moléculaire :271.27 g/molL-Adenosine
CAS :<p>L-Adenosine is a nucleoside that is naturally synthesized in the body and is also found in certain foods. It has a variety of functions, including as an adenosine receptor agonist, a transport agent, and a substrate for metabolic pathways. In addition to its function as an adenosine receptor agonist, L-adenosine can be transported into mammalian cells by facilitated diffusion. The uptake of L-adenosine into cells is dependent on the concentration of extracellular adenosine and its concentration-response curve has been determined experimentally. L-Adenosine also acts as an inhibitor of phosphodiesterase enzyme which increases cAMP levels in cells. This increase in cAMP leads to increased calcium ion influx into the cell, which may lead to activation of protein kinase A (PKA) and protein kinase C (PKC). L-Adenosine has been shown to have cardiac effects at high concentrations. These effects may be</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :267.24 g/molS-(5'-Adenosyl)-L-homocysteine dihydrate
CAS :<p>S-(5'-Adenosyl)-L-homocysteine dihydrate is the active form of homocysteine. It has been shown to inhibit the growth of HL-60 cells and induce apoptosis in these cells. S-(5'-Adenosyl)-L-homocysteine dihydrate binds to dsDNA as a methyltransferase inhibitor, which leads to DNA methylation and inhibits DNA binding. The inhibition of DNA binding prevents transcription, leading to cell death. This drug has also been shown to have an anti-atherosclerotic effect in a model system by inhibiting the adenosine receptor.</p>Formule :C14H20N6O5S•(H2O)2Degré de pureté :Min. 98 Area-%Couleur et forme :PowderMasse moléculaire :420.44 g/mol3-(3-Amino-3-carboxypropyl)uridine
CAS :<p>3-(3-Amino-3-carboxypropyl)uridine is an uridine analog that is used in the study of protein synthesis. It can be used to determine the amino acid sequence of a protein, or to identify proteins with similar sequences. 3-(3-Amino-3-carboxypropyl)uridine can also be used to study enzymatic reactions, such as those involved in the synthesis of polypeptides. This molecule has been shown to produce disulfide bonds and form covalent bonds with other molecules. The three-dimensional structure of this molecule has been determined by NMR spectroscopy and X-ray crystallography.</p>Formule :C13H19N3O8Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :345.31 g/molAdenosine 5'-triphosphate magnesium salt
CAS :<p>Adenosine-5'-triphosphate (ATP) is a nucleotide found in all living cells. It is used as a coenzyme for adenosine kinase, adenosine phosphokinase, and adenosine deaminase. ATP also acts as an important signaling molecule and has been shown to be involved in the regulation of cell metabolism, muscle contraction, and other cellular processes. The human body normally produces enough ATP to meet its needs through aerobic metabolism of glucose or fatty acids, but under certain conditions such as intense muscular activity or insufficient oxygen, more ATP must be produced by anaerobic metabolism. In these situations the mitochondria use glycolysis to produce lactic acid which is then converted into pyruvic acid by the enzyme lactate dehydrogenase. Pyruvic acid is then oxidized by the enzyme pyruvate dehydrogenase complex to produce acetyl-CoA which is further oxidized by the enzyme complex called Krebs</p>Formule :C10H18N5O13P3•xMgDegré de pureté :Min. 95 Area-%Couleur et forme :White Off-White PowderMasse moléculaire :509.20 g/mol6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS :<p>6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.</p>Formule :C12H17N5O4Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :295.3 g/molUridine
CAS :<p>Glycosylated pyrimidine analog; RNA component</p>Formule :C9H12N2O6Degré de pureté :Min. 98 Area-%Couleur et forme :White PowderMasse moléculaire :244.2 g/mol3'-O-(t-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)-5-methyluridine
CAS :<p>3'-O-(t-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)-5-methyluridine is a novel, modified monophosphate nucleoside that can be activated to the corresponding diphosphate by adenosine kinase. The antiviral activity of 3'-O-(t-Butyldimethylsilyl)-2'-O-(2-methoxyethyl)-5-methyluridine has been demonstrated in vitro and in vivo against various viruses including HIV. In addition, this nucleoside phosphoramidite is used for synthesizing DNA and RNA. This product is CAS No. 1221967-92-5, Phosphoramidites, High purity and has a high quality.</p>Formule :C19H34N2O7SiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :430.57 g/molTenofovir disoproxil
CAS :<p>Anti-viral; reverse transcriptase inhibitor</p>Formule :C19H30N5O10PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :519.44 g/molN6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine
CAS :<p>N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine is a sulfur containing compound that is an antibiotic. It has been shown to inhibit the growth of bacteria by binding to their ribosomes, which prevents protein synthesis and cell division. N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine also inhibits chemotaxis in roseobacters, which is the movement of cells or organisms in response to certain factors. This antibiotic may be useful for preventing symbiosis between marine bacteria and other organisms, as it inhibits the motility of these bacteria and their cycling. N6-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoroadenosine also has a genetic determinant that regulates enteric bacteria and clades of ocean bacteria.</p>Formule :C38H34FN5O6Degré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :675.72 g/mol2'-Amino-2'-deoxyinosine
CAS :<p>2'-Amino-2'-deoxyinosine is a modified nucleoside, based on inosine. This compound has a 2'-amino substitution instead of a 2'-hydroxyl group, which has the potential to make the nucleoside more resistant to enzymatic degradation and<br> enhance or alter base-pairing properties.</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :267.24 g/molN4-Benzoyl-2'-deoxy-5'-O-DMT-a-cytidine
CAS :<p>N4-Benzoyl-2'-deoxy-5'-O-DMT-a-cytidine is a modified nucleoside that is synthesized by the reaction of the 2'-deoxyribonucleoside with 4-benzoylchloroformate and dimethoxytrityl. It has antiviral activity against a variety of DNA viruses, including herpes simplex virus type 1 (HSV), herpes simplex virus type 2 (HSV), varicella zoster virus, human cytomegalovirus, Epstein Barr virus, and human immunodeficiency virus. N4-Benzoyl-2'-deoxy-5'-O-DMT-a-cytidine also has anticancer properties and may be used for the treatment of melanoma. This compound shows good results in animal models and clinical trials.</p>Formule :C37H35N3O7Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :633.71 g/mol2'-Bromo-2'-deoxyuridine
CAS :<p>2'-Bromo-2'-deoxyuridine is a synthetic nucleoside analog of deoxyuridine, in which the 2'-hydroxyl group of the ribose sugar is replaced with a bromine atom (Br) at the 2' position. This modification allows it to be incorporated into DNA during DNA synthesis, where it can replace the normal thymidine. This molecule can potentially be used in molecular biology and cell biology as a thymidine analog to study DNA replication, cell proliferation, and DNA repair.</p>Formule :C9H11BrN2O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :307.1 g/molCytidine 3'(2’)-monophosphate
CAS :<p>Cytidine 3’(2’)-monophosphate (CMP) is a biochemical substance that is found in the nucleic acids of cells. It is an equilibrative nucleoside and a precursor to the biosynthesis of uridine and cytidine. CMP is also an intermediate in the synthesis of the coenzyme tetrahydrofolate, which has been shown to inhibit the growth of antibiotic-resistant strains such as Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, and Enterobacter cloacae. Cytidine 3’(2’)-monophosphate can be converted into cytidine by phosphorylation with ATP or by methylation with S-adenosylmethionine. Cytidine 3’(2’)-monophosphate has been shown to have polymerase chain reaction activity</p>Formule :C9H14N3O8PDegré de pureté :Min. 95%Couleur et forme :White PowderMasse moléculaire :323.2 g/mol2'-C-Methylguanosine
CAS :<p>2'-C-Methylguanosine is a synthetic nucleoside analog of guanosine, modified at the 2'-carbon of the ribose sugar with a methyl group. This modification changes the molecule's biological behavior, making it potential useful in antiviral research and biochemical studies, especially those involving RNA synthesis.</p>Formule :C11H15N5O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :297.27 g/mol5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine
CAS :<p>5'-O-Benzoyl-2'-deoxy-N2-isobutyrylguanosine is a novel nucleoside that is synthesized by the modification of 5'-O-benzoyl-2'-deoxyguanosine with 2',3' -diisobutyrylaminopropylidene. It has shown anticancer, antiviral, and antiretroviral properties in vitro. In addition, this compound has been shown to inhibit the growth of human leukemia cells in vivo in a dose dependent manner. The structure of 5'-O-benzoyl-2'-deoxy-N2-isobutyrylguanosine is similar to that of the natural nucleosides adenosine and guanosine.</p>Formule :C21H23N5O6Degré de pureté :Min. 97 Area-%Couleur et forme :Off-White PowderMasse moléculaire :441.45 g/mol5-Chloro-2'-deoxycytidine
CAS :<p>5-Chloro-2'-deoxycytidine (5-Cl-dC) is a nucleoside analog that inhibits DNA synthesis by blocking the action of thymidylate synthase. It can be used in animal models to study bowel diseases, such as ulcerative colitis and Crohn's disease. 5-Cl-dC has been shown to be effective in treating the effects of radiation and chemical toxicity in HL60 cells, a type of human leukemia cell line. 5-Cl-dC has also been shown to enhance the cytotoxicity of eosinophil peroxidase, which is an enzyme that may be involved in the pathogenesis of asthma. This drug is currently being evaluated for its safety and efficacy in clinical trials involving patients with myelodysplastic syndrome or acute myeloid leukemia who are at risk for developing leukemia.</p>Formule :C9H12CIN3O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :261.67 g/mol5-Aminoallyl 2'-deoxyuridine 5'-triphosphate lithium salt - 100mM aqueous solution
CAS :<p>5-Aminoallyl 2'-deoxyuridine 5'-triphosphate lithium salt - 100mM aqueous solution is a novel nucleoside analog with antiviral and anticancer activity. It has been shown to inhibit the replication of HIV-1 in human peripheral blood mononuclear cells and to inhibit tumor growth in mice. This drug also inhibits DNA synthesis, which may be due to its ability to inhibit ribonucleotide reductase and deoxynucleotide reductase, enzymes that are necessary for DNA synthesis.</p>Formule :C12H20N3O14P3·xLiDegré de pureté :Min. 95%Couleur et forme :Colorless PowderMasse moléculaire :523.22 g/molN4-Acetyl-2'-deoxy-5-methylcytidine
<p>N4-Acetyl-2'-deoxy-5-methylcytidine is a novel nucleoside analog of cytidine. It has been shown to be an activator of the immune system, and has antiviral and anticancer properties. This synthetic nucleoside is phosphorylated by kinases in cells to form N4-acetyl-2'-deoxy-5'-methyluridine monophosphate. The phosphate group can be removed by phosphatases in cells to yield N4-acetyl-2'-deoxycytidine, which is a precursor for DNA synthesis.</p>Formule :C12H17N3O5Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :283.28 g/mol5-Aminouridine hydrochloride
CAS :<p>5-Aminouridine hydrochloride is a novel nucleoside that is an inhibitor of RNA polymerase. It has been shown to be active against cancer cells, and is also effective in the treatment of viral infections such as HIV and hepatitis B. 5-Aminouridine hydrochloride is synthesized by reacting uracil with ammonia and hydrogen chloride. The product can be used as a building block for monophosphate or diphosphate analogs, which are important components in the synthesis of DNA and RNA. This product is available at high purity with low impurity levels.</p>Formule :C9H14ClN3O6Degré de pureté :(%) Min. 95%Couleur et forme :PowderMasse moléculaire :295.68 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite
CAS :<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite is a synthetic, antiviral monophosphate nucleoside. It is an activator that increases the activity of other nucleosides and can be used in DNA synthesis by incorporation into DNA molecules. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-1-methylguanosine 3'-CE phosphoramidite has been shown to be effective against Hepatitis C virus, Human Immunodeficiency Virus 1 (HIV), and Herpes Simplex Virus 1.</p>Formule :C47H64N7O8PSiDegré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :914.11 g/mol5'-Amino-5'-deoxyguanosine
CAS :<p>5'-Amino-5'-deoxyguanosine (5-ADG) is an intermediate in the de novo synthesis of guanine nucleotides. It can be synthesized from 5-aminoimidazole ribonucleotide and guanosine monophosphate (GMP). 5-ADG is a substrate for the enzyme GTP cyclohydrolase, which converts it to GMP. This intermediate can also be formed by the action of phosphoryl chloride on 5-aminoimidazole ribonucleotide. The reaction of 5-ADG with malonic acid leads to the formation of inosinic acid, which has been postulated to be a precursor of purines. This conversion is catalyzed by adenylosuccinate synthetase and the enzyme adenylosuccinase.</p>Formule :C10H14N6O4Degré de pureté :Min. 95 Area-%Couleur et forme :PowderMasse moléculaire :282.26 g/molN6,2'-O-Dibutyryladenosine-3',5'-cyclic monophosphate sodium
CAS :<p>N6,2'-O-Dibutyryladenosine-3',5'-cyclic monophosphate sodium (DB-cAMP) is a cyclic nucleoside that has been shown to promote dopaminergic neuron differentiation. It is commonly used in research studies involving the differentiation of induced pluripotent stem cell (iPSC)-derived neurons. This compound acts by activating intracellular signaling pathways that are involved in neuronal development and function. Its ability to enhance dopaminergic neuron differentiation makes it a valuable tool for researchers studying neurodegenerative diseases and exploring potential treatments.</p>Formule :C18H23N5O8PNaDegré de pureté :Min. 95 Area-%Couleur et forme :Off-White PowderMasse moléculaire :491.38 g/mol2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine
CAS :<p>2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine is a synthetic nucleoside. It is an activator for DNA synthesis and has anticancer, antiviral and antifungal properties. This product can be used as a reagent in the synthesis of DNA or RNA. This compound also has high purity and high quality.</p>Formule :C35H36FN5O7Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :657.7 g/molZidovudine
CAS :<p>Inhibitor of reverse transcriptase</p>Formule :C10H13N5O4Degré de pureté :Min. 95%Couleur et forme :Off-White PowderMasse moléculaire :267.24 g/mol8-Aminoadenosine
CAS :<p>8-Aminoadenosine can be used to study the mitochondrial membrane potential, a critical cellular function in which ATP levels are maintained by oxidative phosphorylation. 8-Aminoadenosine is one of the few drugs that have been shown to increase ATP levels in cells. It does this by increasing the permeability of mitochondria membranes and the rate of electron transport from complex I to complex II. The reaction mechanism is thought to involve an intramolecular hydrogen transfer from NADH to 8-aminoadenosine, forming an unstable intermediate that undergoes a conformational change that enables it to react with oxygen. 8-Aminoadenosine has been shown as an effective treatment for certain autoimmune diseases and resistant breast cancer. It also has anti-inflammatory effects, as well as receptor activity against HIV infection and Toll-like receptors.</p>Formule :C10H14N6O4Degré de pureté :Min. 95%Couleur et forme :PowderMasse moléculaire :282.26 g/mol
