CAS 26934-87-2

HT 2 Tossina

Descrizione:

HT 2 Tossina, con il numero CAS 26934-87-2, è una micotossina prodotta da alcune specie di funghi, in particolare quelle appartenenti al genere Fusarium. È principalmente associata a cereali contaminati e può comportare rischi significativi per la salute sia degli esseri umani che degli animali. La tossina è nota per il suo potenziale di causare vari effetti tossicologici, tra cui immunosoppressione e problemi riproduttivi. HT 2 Tossina è classificata come un tricotecene di tipo A, caratterizzato dalla sua capacità di inibire la sintesi proteica nelle cellule, portando a effetti citotossici. La sua struttura chimica presenta un complesso arrangiamento di anelli e gruppi funzionali che contribuiscono alla sua attività biologica. A causa della sua tossicità, le agenzie di regolamentazione monitorano i suoi livelli nei prodotti alimentari e nei mangimi per garantire la sicurezza. Una corretta gestione e test sono essenziali per mitigare i rischi di esposizione, specialmente nei contesti agricoli in cui possono essere presenti colture contaminate. In generale, HT 2 Tossina è una preoccupazione significativa per la sicurezza alimentare e la salute pubblica.

Formula: C₂₂H₃₂O₈

InChI: InChI=1/C22H32O8/c1-11(2)6-16(24)29-14-8-21(9-27-13(4)23)15(7-12(14)3)30-19-17(25)18(26)20(21,5)22(19)10-28-22/h7,11,14-15,17-19,25-26H,6,8-10H2,1-5H3/t14-,15+,17+,18+,19+,20+,21+,22+/m0/s1

InChI key: InChIKey=PNKLMTPXERFKEN-MLXHEQMXSA-N

SMILES: C[C@]12[C@@]3([C@](O[C@]4([C@]1(COC(C)=O)C[C@H](OC(CC(C)C)=O)C(C)=C4)[H])([C@H](O)[C@H]2O)[H])CO3

Sinonimi:

• (2alpha,3beta,4alpha,5alpha,6beta,8beta,11beta,12R)-15-(acetyloxy)-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
• (3beta,4alpha,8alpha,12R)-15-(acetyloxy)-3,4-dihydroxy-12,13-epoxytrichothec-9-en-8-yl 3-methylbutanoate
• 12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-
• 12,13-Epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol 15-acetate 8-isovalerate
• 15-Acetoxy-3,4-dihydroxy-8-(3-methylbutyryloxy)-12,13-epoxy delta9-trichothecene
• 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ⁹-trichothecene
• HT 2 mycotoxin
• Ht-2
• Isovaleric acid, 8-ester with 12,13-epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 15-acetate
• Mycotoxin HT 2
• Nsc 278571
• Spiro[2,5-methano-1-benzoxepin-10,2′-oxirane], trichothec-9-ene-3,4,8,15-tetrol deriv.
• Toxin HT 2
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15 acetate 8-(3-methylbutanoate), (3alpha,4abeta,8alpha)- (9CI)
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)- (9CI)
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3α,4β,8α)-
• Trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol, 12,13-epoxy-, 15-acetate, 8-isovalerate
• Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate (8CI)
• Trichothec-9-ene-3α,4β,8α,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
• HT 2 Toxin
• 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ9-trichothecene
• (3alpha,4beta,8alpha)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate)
• mycotoxinht2
• T-2, Toxin analog
• HT-2 toxin, FroM FusariuM sp.
• 15-Acetoxy-3alpha-4beta-dihydoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• HT-2 Toxin (3alpha,4beta,8alpha)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 15-acetate 8-(3-methylbutanoate)
• 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetrol 15-acetate 8-(3-methylbutanoate)
• 12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol15-acetate8-iso
• 4-beta,8-alpha,15-tetrol,12,13-epoxy-,15-acetate,8-trichothec-9-ene-3-alph
• HT-2 toxin 100ug/ml in ACN
• 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-8ALPHA-[3-METHYLBUTYRYLOXY]-12,13-EPOXYTRICHOTHEC-9-ENE
• HT-2 toxin, 99%, from Fusarium sp.
• Trichothen-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate)
• U-[13C22]-HT-2 Toxin Solution, 25μg/mL
• Pentanoic acid anion
• (3α,4β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate) 15-Acetate
• 12,13-Epoxytrichothec-9-ene-3α,4β,8α,15-tetro 15-Acetate 8-Isovalerate
• valerate
• ht-2toxin solution
• 15-acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• HT-2 toxin,15-Acetoxy-3α,4β-dihydroxy-8α-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-ene
• Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 15-acetate 8-isovalerate
• Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 15-acetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-

HT-2 Toxin in Acetonitrile

Prodotto controllato

CAS: 26934-87-2

Ref: BE-BePure-25756XA

HT-2 toxin

Prodotto controllato

CAS: 26934-87-2

HT-2 toxin

Formula: C₂₂H₃₂O₈

Purezza: 99% (tlc) (Typical Value in Batch COA)

Colore e forma: Solid

Peso molecolare: 424.49

Ref: 54-BIH1001

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Prodotto controllato

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8, 5975-78-0

Colore e forma: Colourless

Ref: 04-V30000004AL

A + B-Trichothecenes and Zearalenone Mixture 10 µg/mL in Acetonitrile

Prodotto controllato

CAS: 17924-92-4, 21259-20-1, 2270-40-8, 23255-69-8, 23282-20-4, 26934-87-2, 50722-38-8, 51481-10-8

Colore e forma: Colourless

Ref: 04-A30000004AL

Fusarium Toxins Mixture 10-100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 17924-92-4, 21259-20-1, 26934-87-2, 51481-10-8, 5975-78-0

Colore e forma: Mixture

Ref: 04-V30000007AL

HT-2 Toxin 100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 26934-87-2

Formula: C₂₂H₃₂O₈

Colore e forma: Colourless

Peso molecolare: 424.48

Ref: 04-A14214000AL-100

HT-2 Toxin 100 µg/mL in Acetonitrile

Prodotto controllato

CAS: 26934-87-2

Formula: C₂₂H₃₂O₈

Colore e forma: Colourless Liquid

Peso molecolare: 424.48

Ref: 04-V14214000AL-100

HT-2 Toxin-d3

Prodotto controllato

CAS: 26934-87-2

Formula: C₂₂H₂₉D₃O₈

Peso molecolare: 427.51

Ref: 4Z-M-214005

HT-2 Toxin

Prodotto controllato

CAS: 26934-87-2

Formula: C₂₂H₃₂O₈

Peso molecolare: 424.49

Ref: 4Z-M-214004

HT-2 Toxin-13C-d3

Prodotto controllato

CAS: 26934-87-2

Formula: C₂₁₁₃CH₂₉D₃O₈

Peso molecolare: 428.50

Ref: 4Z-M-214006

HT-2 Toxin (>85%)

Prodotto controllato

CAS: 26934-87-2

Stability Hygroscopic
Applications HT-2 Toxin is a trichothecene group mycotoxin. HT-2 Toxin is the 4-hydroxy analogue of T-2 Toxin (T002980) which has been shown to induce DNA damage and cell death on prolonged administration.Environmental contaminants; Food contaminants
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Weidner, M. et al.: J. Agric. Food Chem., 60, 5676 (2012); Choi, H. et al.: Toxicol. Appl. Pharmacol., 240, 46 (2009); Amuzie, C. et al.: Toxicol. Sci., 113, 412 (2010);

Formula: C₂₂H₃₂O₈

Purezza: >85%

Colore e forma: Neat

Peso molecolare: 424.48

Ref: TR-H671800

HT-2 Toxin

Prodotto controllato

CAS: 26934-87-2

Ref: BE-BePure-25756

HT-2 Toxin

Prodotto controllato

CAS: 26934-87-2

Ref: BE-RMCM281004

HT-2 Toxin in Acetonitrile

Prodotto controllato

CAS: 26934-87-2

Acetonitrile

Ref: BE-BePure-25756XA-100

HT-2 Toxin

Prodotto controllato

CAS: 26934-87-2

HT-2 Toxin is a toxin that is produced by the bacteria Clostridium botulinum. The HT-2 toxin is used as an analytical method to determine the concentration of this toxin in food, and as a research tool for studying the effects of toxins on cell membrane potential. HT-2 Toxin binds to the mitochondria of cells and causes a loss in mitochondrial membrane potential, which leads to cell death. The HT-2 toxin has been shown to be inhibitory at doses below those that would lead to full lethality. It is also highly sensitive to glycosidic bonds, which are found in many foods, such as malonic acid and zearalenone. These two compounds have been shown to be inhibitors of glycosidase enzymes, which may play a role in the detoxification process. The HT-2 toxin can also induce autophagy in cells that are resistant to its toxic effects.

Formula: C₂₂H₃₂O₈

Purezza: Min. 95%

Peso molecolare: 424.49 g/mol

Ref: 3D-BH162733