Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(144 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(139 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(93 prodotti)
- c-RET(62 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6070 prodotti di "Apoptosi"
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Thalidomide-Piperazine-PEG1-NH2
CAS:Thalidomide-Piperazine-PEG1-NH2 is a synthetic E3 ligase ligand-linker conjugate, featuring a cereblon ligand based on Thalidomide and a single linker.Formula:C21H27N5O5Peso molecolare:429.47Antitumor agent-78
Antitumor agent-78 blocks GPx-4, raises COX2, triggers apoptosis, halts EMT, and stifles cancer cell growth and migration.Colore e forma:SoildAntitumor agent-100
CAS:Antitumor Agent-100 (compound A6) is a molecular gel and apoptosis inducer targeting PDE3A-SLFN12 with an IC50 of 0.3 μM, demonstrating potent antitumor activity. This orally available agent binds to the PDE3A enzyme pocket, recruiting and stabilizing SLFN12 which disrupts protein translation and induces apoptosis [1].Formula:C17H14ClN3OPeso molecolare:311.77RMS5
CAS:RMS5: hambanine analogue, inhibits P-gp, anti-cancer with cytotoxic, anti-proliferative effects, reduces Bcl-2 proteins, cleaves PARP.Formula:C35H38N2O5SColore e forma:SolidPeso molecolare:598.75Anticancer agent 68
CAS:Compound 12, an anticancer agent, halts G2/M phase, triggers cell death, and activates p53 & PTEN for tumor suppression.Formula:C20H18ClNO5Colore e forma:SolidPeso molecolare:387.81VEGFR-2-IN-14
VEGFR-2-IN-14 (Compound 5) is a potent inhibitor of VEGFR-2, which inhibits the growth of HepG2 cells in the Pre-G1 phase and induces apoptosis.Formula:C24H23N3O3SColore e forma:SolidPeso molecolare:433.52MG-B-28
MG-B-28, a BTLA-HVEM inhibitor, demonstrates an IC50 value of 906 nM. It promotes T cell activation dose-dependently by inhibiting the interaction between BTLA and HVEM.Formula:C28H25N5O3Colore e forma:SolidPeso molecolare:479.53p53 Activator 8
CAS:p53 Activator 8 (compound 5), a potent p53 activator, exhibits significant anti-proliferative effects on MCF7 breast cancer cell lines, demonstrating an IC 50 value of 0.5 μM [1] [2].Formula:C15H17NO2SPeso molecolare:275.37Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride
CAS:<p>Thalidomide-NH-amido-PEG2-C2-NH2 hydrochloride is a synthetic E3 ligase ligand-linker conjugate, comprised of a cereblon ligand based on Thalidomide and a linker, utilized in the synthesis of PROTACs.</p>Formula:C21H28ClN5O7Peso molecolare:497.93Anticancer agent 64
CAS:Anticancer agent 64 (5m) induces apoptosis, has IC50 2.4μM in CCRF-CEM, activates caspases, cleaves PARP, affects mitochondria.Formula:C31H46N2O2SColore e forma:SolidPeso molecolare:510.77TNF-α-IN-14
CAS:TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].Formula:C22H26O6Colore e forma:SolidPeso molecolare:386.44FLT3/TrKA-IN-1
FLT3/TrKA-IN-1: Potent dual kinase inhibitor for FLT3 & TrKA, promising for AML research.Formula:C28H30N4O2Colore e forma:SolidPeso molecolare:454.56SY-5609
CAS:SY-5609 (CDK7-IN-3) is a selective non-covalent CDK7 inhibitor, with weak inhibitory activity against CDK2, CDK9 and CDK12.Cost-effective and quality-assured.Formula:C23H26F3N6OPPurezza:99.34% - >99.99%Colore e forma:SolidPeso molecolare:490.46Ref: TM-T36038
1mg139,00€2mg200,00€5mg343,00€10mg553,00€25mgPrezzo su richiesta50mgPrezzo su richiesta1mL*10mM (DMSO)373,00€Nalmefene
CAS:Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used in the study of opioid overdose and alcohol dependence.Formula:C21H25NO3Purezza:99.86%Colore e forma:SolidPeso molecolare:339.43Tuvusertib
CAS:Tuvusertib (M1774), an oral ATR inhibitor (Ki<1µM), selectively blocks CHK1 phosphorylation, disrupts DNA repair, and induces tumor cell apoptosis.Formula:C16H12F2N8OPurezza:98.44% - 99.66%Colore e forma:SolidPeso molecolare:370.32Ref: TM-T10406
1mg62,00€5mg131,00€10mg197,00€25mg383,00€50mg533,00€100mg757,00€1mL*10mM (DMSO)150,00€UH15-38
CAS:UH15-38 is a potent and selective RIPK3 inhibitor that blocks necroptosis in alveolar epithelial cells triggered by IAV, useful for studying lung inflammation.Formula:C26H27N5O2Purezza:99.85%Colore e forma:SolidPeso molecolare:441.53Lometrexol
CAS:<p>Lometrexol (LY 264618) is an antifolate that inhibits GARFT, blocks purine synthesis, induces apoptosis, and has anticancer properties.</p>Formula:C21H25N5O6Purezza:97.76% - 99.56%Colore e forma:SolidPeso molecolare:443.45Milademetan
CAS:Milademetan (DS-3032), an MDM2 inhibitor, exhibits antitumor activity, induces G1 cell cycle arrest and apoptosis, and can be used to study solid tumors.Formula:C30H34Cl2FN5O4Purezza:>99.99%Colore e forma:SolidPeso molecolare:618.53Ref: TM-T12040
1mg87,00€5mg170,00€10mg274,00€25mg518,00€50mg847,00€100mg1.454,00€1mL*10mM (DMSO)234,00€HC-5404
CAS:HC-5404 is a potent and selective PERK inhibitor, blocking the activation of the PERK pathway, anti-tumor effects, advanced solid tumors and renal cell Cancer.Formula:C24H24F2N4O3Purezza:99.33%Colore e forma:SolidPeso molecolare:454.47PF-07328948
CAS:PF-07328948 is a branched-chain keto-acid dehydrogenase kinase (BDK) inhibitor, useful for studying CVD metabolic disorders.Formula:C16H8F4O3SPurezza:98.42%Colore e forma:SolidPeso molecolare:356.29Zharp1-211
CAS:Zharp1-211 is a RIPK3 inhibitor，reduces JAK/ stat1-mediated chemokines and MHC class II molecules in IECs, (GVHD) for gastrointestinal inflammation.Formula:C24H25N5O4Purezza:99.71%Colore e forma:SolidPeso molecolare:447.49Ref: TM-T87664
1mg87,00€5mg183,00€10mg283,00€25mg562,00€50mg873,00€100mg1.311,00€200mg1.768,00€1mL*10mM (DMSO)202,00€BCL6-IN-3
CAS:BCL6-IN-3: potent BCL6 inhibitor, 70 nM GI50 in SU-DHL4, affects cell functions, antitumor.Formula:C24H31ClF2N6O2Purezza:98.17%Colore e forma:SolidPeso molecolare:508.99Ref: TM-T10487
1mg115,00€5mg255,00€10mg375,00€25mg562,00€50mg787,00€100mg1.074,00€500mgPrezzo su richiesta1mL*10mM (DMSO)391,00€Vatalanib hydrochloride
CAS:Vatalanib hydrochloride (PTK787 hydrochloride) is an orally available and highly potent tyrosine kinase (VEGF) inhibitor that reduces the number and size of Aβ plaques in the cortex of 5xFAD mice, which may be useful in the study of Alzheimer's disease and cancer.Formula:C20H16Cl2N4Purezza:99.7%Colore e forma:SolidPeso molecolare:383.27Zotatifin
CAS:Zotatifin (eFT226) is a selective eIF4A inhibitor with antiviral and antitumor properties, inhibiting Sox4 translation and inducing apoptosis.Formula:C28H29N3O5Purezza:98.85%Colore e forma:SolidPeso molecolare:487.55Darizmetinib
CAS:Darizmetinib (HRX215) is an MKK4 inhibitor.Formula:C21H17F2N5O3SPurezza:98.03% - 99.57%Colore e forma:SolidPeso molecolare:457.45Ref: TM-T72956
1mg72,00€2mgPrezzo su richiesta5mg156,00€10mg235,00€25mg343,00€50mg423,00€100mg620,00€1mL*10mM (DMSO)157,00€Gemcitabine elaidate hydrochloride
CAS:<p>CP-4126, a lipophilic pro-drug of Gemcitabine, converts to active form by esterases, allowing oral administration with dose-dependent effects.</p>Formula:C27H44ClF2N3O5Purezza:98.50% - 99.6%Colore e forma:SolidPeso molecolare:564.11JAK2-IN-7
CAS:JAK2-IN-7 selectively inhibits JAK2 (IC50: 3 nM), shows 14-fold selectivity over JAK1/3, FLT3, induces G0/G1 arrest, apoptosis, and has antitumor effects.Formula:C26H33N7OPurezza:99.54%Colore e forma:SolidPeso molecolare:459.59Ref: TM-T35900
1mg145,00€5mg354,00€10mg630,00€25mg1.301,00€50mg1.738,00€100mg2.357,00€1mL*10mM (DMSO)358,00€FX-11
CAS:<p>FX-11: potent LDHA inhibitor (Ki 8 μM), activates PKM2, reduces ATP, induces oxidative stress/ROS, cell death, shows antitumor effects.</p>Formula:C22H22O4Purezza:98.95%Colore e forma:SolidPeso molecolare:350.41AP1867-3-(aminoethoxy)
CAS:AP1867-3-(aminoethoxy) is a synthetic ligand for FKBP and can be used in the synthesis of PROTAC FKBP12 F36V degrader.Formula:C38H50N2O9Colore e forma:SolidPeso molecolare:678.81β-Zearalanol
CAS:Beta-Zearalenol, a derivative of zearalenone (ZEA) capable of conjugating with glucuronic acid[2], is a mycotoxin produced by Fusarium spp. It induces apoptosis and oxidative stress in mammalian reproductive cells[1].Formula:C18H26O5Colore e forma:SolidPeso molecolare:322.4OBAA
CAS:OBAA is a potent inhibitor of phospholipase A2 (PLA2) with an IC 50 of 70 nM. OBAA blocks Melittin-induced Ca 2+ influx in Trypanosoma brucei with an IC 50 of 0.4 μM [1] [2] [3].Formula:C28H44O3Purezza:98%Colore e forma:SolidPeso molecolare:428.65PIM-447 dihydrochloride
CAS:PIM-447 dihydrochloride is an orally available and selective inhibitor of pan-PIM kinase(Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively).Formula:C24H25Cl2F3N4OPurezza:98%Colore e forma:SolidPeso molecolare:513.38WEHI-539 hydrochloride
CAS:WEHI-539 hydrochloride is a selective Bcl-XL inhibitor with an IC50 of 1.1 nM.Formula:C31H30ClN5O3S2Purezza:98%Colore e forma:SolidPeso molecolare:620.18(R)-Verapamil hydrochloride
CAS:(R)-Verapamil hydrochloride ((R)-(+)-Verapamil hydrochloride) is an inhibitor of P-Glycoprotein.Formula:C27H39ClN2O4Colore e forma:SolidPeso molecolare:491.065-Amino-1-β-D-ribofuranosyl-1H-imidazole-4-carboxamide
CAS:Formula:C9H14N4O5Purezza:95%Colore e forma:SolidPeso molecolare:258.2313Platinum, diammine[1,1-cyclobutanedi(carboxylato-kO)(2-)]-, (SP-4-2)-
CAS:Formula:C6H10N2O4PtPurezza:98%Colore e forma:SolidPeso molecolare:369.2326Ref: IN-DA00I84B
Prodotto fuori produzionePRGL493
CAS:PRGL493 blocks ACSL4, halts PC3/MDA-MB-231 cancer cell spread, and inhibits MA-10 tumor progesterone. Effective in mouse PC3 tumor model at 0.25 mg/kg.Formula:C25H21N7O2Purezza:98.80% - 99.11%Colore e forma:SolidPeso molecolare:451.48Vatiquinone
CAS:Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, optimizing metabolic control, enhancFormula:C29H44O3Colore e forma:SolidPeso molecolare:440.66Thalidomide-O-amido-C4-NH2 hydrochloride
CAS:Thalidomide-O-amido-C4-NH2 hydrochloride, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand derived from Thalidomide with a linker and is commonly used in the synthesis of PROTACs[1].Formula:C19H23ClN4O6Purezza:98%Colore e forma:SolidPeso molecolare:438.86Swainsonine
CAS:Swainsonine (Tridolgosir) is an alkaloid isolated from Astragalus membranaceus and is a potent and reversible inhibitor of alpha-mannosidase. swainsonine has antitumour activity and induces apoptosis and cell cycle arrest in the G2/M phase.Formula:C8H15NO3Purezza:98%Colore e forma:Lyophilized PowderPeso molecolare:173.21Mcl-1 inhibitor 6
CAS:Mcl-1 inhibitor 6 binds Mcl-1 with KD 0.23 nM and Ki 0.02 μM, shows strong selectivity over Bcl-2 family, and demonstrates antitumor efficacy.Formula:C26H28ClNO6SColore e forma:SolidPeso molecolare:518.02Imifoplatin
CAS:Imifoplatin (PT-112) is a platinum compound with antitumor activity and may be used to study prostate cancer and immune system disorders.Formula:C6H16N2O7P2PtPurezza:≥95.0%Colore e forma:SolidPeso molecolare:485.23Ciprofloxacin lactate
CAS:Ciprofloxacin lactate is a useful organic compound for research related to life sciences. The catalog number is T66299 and the CAS number is 97867-33-9.Formula:C20H24FN3O6Colore e forma:SolidPeso molecolare:421.43MI-773
CAS:MI-773 is a potent inhibitor of the MDM2-p53 protein interaction (PPI) with a high affinity for MDM2 and a Kd value of 8.2 nM. MI-773 exhibits antitumour effects.Formula:C29H34Cl2FN3O3Colore e forma:SolidPeso molecolare:562.5Thalidomide-O-C6-COOH
CAS:Thalidomide-O-C6-COOH is a synthetic conjugate that combines a Thalidomide-derived cereblon ligand with a PROTAC technology linker (E3 ligase ligand-linker).Formula:C20H22N2O7Colore e forma:SolidPeso molecolare:402.403Ingenol 3,20-dibenzoate
CAS:Ingenol 3,20-dibenzoate is a powerful activator of protein kinase C (PKC) isoforms that effectively induces the translocation of nPKC-delta, -epsilon, and -theta, as well as PKC-mu, from the cytosolic fraction to the particulate fraction. Through de novo synthesis of macromolecules, it triggers apoptosis with characteristic morphology. Moreover, Ingenol 3,20-dibenzoate enhances IFN-γ production and degranulation in NK cells, particularly when stimulated by NSCLC cells[1][2].Formula:C34H36O7Colore e forma:SolidPeso molecolare:556.65Ac-IETD-CHO TFA
Ac-IETD-CHO TFA is a granzyme B and caspase-8 inhibitor that inhibits caspase8 activity by blocking caspase3 precursor cleavage.Ac-IETD-CHO TFA inhibits Fas-mediated apoptosis.Formula:C23H35F3N4O12Colore e forma:SoildPeso molecolare:616.54A-192621
CAS:A-192621 is a potent, nonpeptide, orally active, and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. A-192621 promotes apoptosis in PASMCs and elevates both arterial blood pressure and plasma ET-1 levels[1][2][3]. Its selectivity is 636-fold higher for ETB than ETA (IC50 of 4280 nM and Ki of 5600 nM).Formula:C33H38N2O6Purezza:98%Colore e forma:SolidPeso molecolare:558.66Yatein
CAS:Yatein inhibits herpes simplex virus type 1 replication by interruption the immediate-early gene expression. Yatein is a lignan isolated from A. chilensis. It also has antiproliferative activity.Formula:C22H24O7Purezza:98%Colore e forma:SolidPeso molecolare:400.42Carubicin hydrochloride
CAS:Carubicin HCl is an anthracycline antineoplastic antibiotic. Through intercalates into DNA and interacts with topoisomerase II, Carubicin inhibits DNA replication and repair and RNA and protein synthesis.Formula:C26H28ClNO10Colore e forma:SolidPeso molecolare:549.95DB818
CAS:DB818 is a synthetic Homeobox A9 (HOXA9) inhibitor and can be used for research on the treatment of acute myeloid leukaemia associated with HOXA9 overexpression.Formula:C19H16N6SPurezza:98%Colore e forma:SolidPeso molecolare:360.44SCH79797
CAS:SCH79797 is a potent and specific protease-activated receptor 1 (PAR1) antagonistwith antimicrobial, anticancer, anti-inflammatory, and neuroprotective effects.Formula:C23H25N5Purezza:99.80%Colore e forma:SolidPeso molecolare:371.48Prostaglandin A2
CAS:PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity.[1] At a 25 uM concentration, PGA2 blocks the cell cycle progression of NIH 3T3 cells at the G1 and G2/M phase .[2] It has also been shown to act as a vasodilator with natriuretic properties.[3]Formula:C20H30O4Colore e forma:SolidPeso molecolare:334.45BPH-675
CAS:BPH-675 is a bioactive chemical.Formula:C24H23NO9P2SColore e forma:SolidPeso molecolare:563.45Thalidomide-O-C5-NH2 hydrochloride
CAS:Thalidomide-O-C5-NH2 hydrochloride is a synthetic compound consisting of a ligand-linker conjugate with E3 ligase activity. It combines a cereblon ligand based on Thalidomide and a linker commonly utilized in PROTAC technology.Formula:C18H22ClN3O5Colore e forma:SolidPeso molecolare:395.84XMU-MP-3
CAS:XMU-MP-3 is a robust, non-covalent inhibitor of BTK, exhibiting exceptional potency with IC50 values of 10.7 nM and 17.0 nM for BTK WT and BTK C481S mutation, respectively, in the presence of 10 μM ATP. Moreover, XMU-MP-3 elicits apoptosis.Formula:C27H27F3N8OColore e forma:SolidPeso molecolare:536.563RRD-251
CAS:RRD-251 is an Rb-Raf-1 interaction inhibitor that induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine[1].Formula:C8H9Cl3N2SColore e forma:SolidPeso molecolare:271.59Thalidomide-5-COOH
CAS:Thalidomide-5-COOH is a useful organic compound for research related to life sciences. The catalog number is T64600 and the CAS number is 1216805-11-6.Formula:C14H10N2O6Colore e forma:SolidPeso molecolare:302.242ENMD-2076 tartrate
CAS:ENMD-2076 is an orally active kinase inhibitor. It also has antiangiogenic and antiproliferative mechanisms of action.Formula:C25H31N7O6Colore e forma:SolidPeso molecolare:525.56Dihydroartemisinin (mixture of α and β isomers)
CAS:Dihydroartemisinin (mixture of α and β isomers) is a useful organic compound for research related to life sciences. The catalog number is T64399 and the CAS number is 131175-87-6.Formula:C15H24O5Colore e forma:SolidPeso molecolare:284.352CTB
CAS:<p>CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.</p>Formula:C16H13ClF3NO2Purezza:99.82%Colore e forma:SolidPeso molecolare:343.73Faradiol 3-Myristate
CAS:Prodotto controllatoFormula:C44H76O3Colore e forma:NeatPeso molecolare:653.072anti-TNBC agent-2
CAS:<p>Anti-TNBC agent-2 (3j), a purine derivative, acts as an anti-triple negative breast cancer (TNBC) therapeutic.</p>Formula:C28H37ClFN7OPurezza:98%Colore e forma:SolidPeso molecolare:542.09Ref: TM-T79699
Prodotto fuori produzioneTaltobulin
CAS:Taltobulin (HTI-286) is a synthetic analog of the tripeptide cysteine, a microtubule protein inhibitor that inhibits liver tumor cell proliferation in vitro and tumor growth in vivo.Taltobulin is cytotoxic, induces mitotic arrest and apoptosis, and may be used in the study of breast cancer and microtubule tissue-related diseases.Formula:C27H43N3O4Purezza:99.86%Colore e forma:SolidPeso molecolare:473.65CHMFL-48
CAS:<p>CHMFL-48, an orally active inhibitor of BCR-ABL kinase, demonstrates efficacy against both the wild-type (wt) and various imatinib-resistant mutants. It exhibits potent inhibitory activity, with IC 50 values of 1 nM for the ABL wild-type and 0.8 nM for the ABL T315I mutant. CHMFL-48 operates by inhibiting the autophosphorylation of both wild-type and mutant BCR-ABL, affecting downstream signaling mediators including STAT5 and CRKL. This disruption leads to cell cycle arrest and triggers apoptosis. Given its properties, CHMFL-48 is a promising candidate for research on chronic myeloid leukemia (CML).</p>Formula:C31H30F3N7OColore e forma:SolidPeso molecolare:573.61IHMT-MST1-39
CAS:<p>IHMT-MST1-39 is an orally effective MST kinase inhibitor with IC50 values of 42 nM for MST1 and 109 nM for MST2. It activates the AMPK signaling pathway in hepatocytes and inhibits apoptosis in pancreatic β cells. Additionally, IHMT-MST1-39 improves type 1 diabetes in mice induced by Streptozotocin.</p>Formula:C20H18F2N6O3SColore e forma:SolidPeso molecolare:460.46Ref: TM-T200512
Prodotto fuori produzioneZSQ836
CAS:<p>ZSQ836 is a dual covalent inhibitor of CDK12/CDK13 with oral bioactivity, displaying an EC50 value of 32 nM against CDK12. This compound can induce cell apoptosis (apoptosis) and demonstrates in vivo anticancer properties. ZSQ836 is applicable for research in ovarian cancer.</p>Formula:C27H28AsClN6OS2Colore e forma:SolidPeso molecolare:627.05Ref: TM-T200333
Prodotto fuori produzioneCyy-272
CAS:<p>Cyy-272 is an orally active JNK inhibitor with IC50 values of 1.25, 1.07, and 1.24 μM against JNK1, JNK2, and JNK3, respectively. It exerts anti-inflammatory effects by inhibiting the phosphorylation of JNK, thereby alleviating acute lung injury (ALI) induced by lipopolysaccharide (LPS). Moreover, Cyy-272 significantly reduces inflammation in cardiomyocytes and cardiac tissues caused by high lipid concentrations, further mitigating resultant cardiac hypertrophy, fibrosis, and apoptosis. Cyy-272 is utilized in the study of obesity-related myocarditis.</p>Formula:C23H23F2N7Colore e forma:SolidPeso molecolare:435.47Ref: TM-T200453
Prodotto fuori produzioneSMIP34
CAS:<p>SMIP34 is an inhibitor of PELP1 that demonstrates the capability to reduce cell viability and colony formation. Additionally, SMIP34 induces cell apoptosis (apoptosis) and causes cell cycle arrest in the S phase. It reduces the expression of PELP1 and exhibits anti-tumor activity. SMIP34 also has potential for research in triple-negative breast cancer (TNBC).</p>Formula:C20H15ClFN5O2SColore e forma:LiquidPeso molecolare:443.88DETD-35
CAS:<p>DETD-35 is a promising chemical compound in anti-melanoma therapy, functioning as an inhibitor of the MEK-ERK, Akt, and STAT3 signaling pathways. It enhances cancer cell apoptosis (Apoptosis) and diminishes resistance to Vemurafenib in cancer cells. The compound exhibits IC 50 values of 2.7, 6.0, 3.9, 3.1, and 2.5 μM against melanoma cell lines B16-F10, MeWo, SK-MEL-2, A2058c, and A375c, respectively. DETD-35 offers significant potential for advancing research in melanoma treatment strategies.</p>Formula:C27H24O6Colore e forma:SolidPeso molecolare:444.48
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