Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(1 prodotti)
- Caspasi(154 prodotti)
- FOXO1(2 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(113 prodotti)
- PDK(9 prodotti)
- PERK(26 prodotti)
- Chinasi di serina/treonina(18 prodotti)
- Survivin(14 prodotti)
- TNF(65 prodotti)
- c-RET(61 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 6107 prodotti di "Apoptosi"
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BEPP monohydrochloride
CAS:BEPP monohydrochloride is a double-strand RNA-dependent protein kinase (PKR) activator.Formula:C23H24ClN3O2Colore e forma:SolidPeso molecolare:409.91AZD 1152 (hydrochloride)
CAS:AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.Formula:C26H33Cl2FN7O6PColore e forma:SolidPeso molecolare:660.47SMI-6860766
CAS:SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.Formula:C15H11BrClNOPurezza:98%Colore e forma:SolidPeso molecolare:336.61Fomesafen
CAS:Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).Formula:C15H10ClF3N2O6SPurezza:99.91% - 99.93%Colore e forma:White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicidePeso molecolare:438.76SMIP004
CAS:SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.Formula:C13H19NOPurezza:99.86%Colore e forma:SolidPeso molecolare:205.3PI3Kδ-IN-11
CAS:PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.Formula:C27H21N5OColore e forma:SolidPeso molecolare:431.49MG-115
CAS:MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.Formula:C25H39N3O5Purezza:97.10%Colore e forma:White PowderPeso molecolare:461.59RET-IN-6
CAS:RET-IN-6 is a potent inhibitor of RET (IC50: 4.57 nM).Formula:C30H29N7Colore e forma:SolidPeso molecolare:487.6KS106
CAS:KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.Formula:C18H15BrF3N3O2SPurezza:99.31%Colore e forma:SolidPeso molecolare:474.3BCL6-IN-8c
CAS:BCL6-IN-8c is an orally active and potent inhibitor of B-cell lymphoma 6 (BCL6)-corepressor interaction(IC50 of 0.10 μM in cell-free enzyme-linked immunosorbentFormula:C20H20ClN3O5Colore e forma:SolidPeso molecolare:417.84SCH529074
CAS:SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.Formula:C31H36Cl2N6Purezza:99.57%Colore e forma:SolidPeso molecolare:563.56Ref: TM-T37042
1mg34,00€2mg43,00€5mg60,00€10mg99,00€25mg208,00€50mg310,00€100mg444,00€1mL*10mM (DMSO)72,00€D44
CAS:D44 is a Plasmodium FKBPs inhibitor.Formula:C16H16N4OSColore e forma:SolidPeso molecolare:312.39PDK4-IN-1
CAS:PDK4-IN-1 is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4)(IC50 value of 84 nM).Formula:C22H19N3O2Purezza:98%Colore e forma:SolidPeso molecolare:357.41KU-0058948
CAS:KU-0058948: PARP inhibitor, triggers cell cycle arrest and apoptosis in myeloid leukemia cells in vitro.Formula:C21H21FN4O2Colore e forma:SolidPeso molecolare:380.42VMY-1-103
CAS:VMY-1-103: a strong CDK inhibitor better than purvalanol B; halts prostate/breast cancer cell growth, induces apoptosis, may treat medulloblastoma.Formula:C34H42ClN9O4SColore e forma:SolidPeso molecolare:708.27MDK-4204
CAS:MDK-4204, an anticancer agent, shows significant anti-cancer activity with IC50 values of 8.8 µM and 9.5 µM in PC-3 and DU-145 cells, respectively.Formula:C31H29FN4OPurezza:98%Colore e forma:SolidPeso molecolare:492.59NU-8165
CAS:NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.Formula:C24H22ClNO3Purezza:98%Colore e forma:SolidPeso molecolare:407.89Arecaidine propargyl ester (hydrobromide)
CAS:Arecaidine propargyl ester: selective M2 muscarinic receptor agonist, induces guinea pig atrium contraction, lowers cat blood pressure, toxic to flies.Formula:C10H14BrNO2Colore e forma:SolidPeso molecolare:260.13Ivaltinostat
CAS:CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.Formula:C24H33N3O4Purezza:98%Colore e forma:SolidPeso molecolare:427.54KF24345
CAS:KF24345 is an inhibitor of adenosine uptake.Formula:C31H38N6O5Colore e forma:SolidPeso molecolare:574.67TP-472
CAS:TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).Formula:C20H19N3O2Purezza:98%Colore e forma:SolidPeso molecolare:333.38GW7845
CAS:GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.Formula:C29H28N2O6Purezza:98%Colore e forma:SolidPeso molecolare:500.54EGFR-IN-52
CAS:EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.Formula:C19H18N4O3SColore e forma:SolidPeso molecolare:382.44Anticancer agent 42
CAS:Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.Formula:C19H16Cl2N2O3Colore e forma:SolidPeso molecolare:391.25D-Cl-amidine
CAS:D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.Formula:C14H19ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:310.78ATB-337
CAS:S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.Formula:C23H15Cl2NO2S3Colore e forma:SolidPeso molecolare:504.47DC-CPin711
CAS:DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.Formula:C23H22N4O2Colore e forma:SolidPeso molecolare:386.45WK-298
CAS:WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.Formula:C35H38Cl2N6OPurezza:98%Colore e forma:SolidPeso molecolare:629.62CDK/HDAC-IN-2
CAS:CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.Formula:C25H20Cl2N6O3Colore e forma:SolidPeso molecolare:523.37BJE6-106
CAS:BJE6-106, Selective PKCδ inhibitor (IC50=0.05 μM), induces caspase-dependent apoptosis, activates JNK/H2AX, for NRAS-mutated melanoma.Formula:C26H23NO2Colore e forma:SolidPeso molecolare:381.47Semapimod
CAS:Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.Formula:C34H52N18O2Colore e forma:SolidPeso molecolare:744.9Didesmethylrocaglamide
CAS:Didesmethylrocaglamide, a Rocaglamide derivative, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor that exhibits strong growth-inhibitory effects,Formula:C27H27NO7Colore e forma:SolidPeso molecolare:477.51NSC114792
CAS:NSC114792 is a selective JAK3 inhibitor.Formula:C26H32N4O2SPurezza:98%Colore e forma:SolidPeso molecolare:464.62Mcl1-IN-4
CAS:Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formula:C28H26N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.58Nafamostat hydrochloride
CAS:Nafamostat hydrochloride is a synthetic serine protease inhibitor and is an anticoagulant.Formula:C19H19Cl2N5O2Purezza:98%Colore e forma:SolidPeso molecolare:420.29Mcl1-IN-3
CAS:Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.Formula:C27H22ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:487.93PD1-PDL1-IN 1
CAS:PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.Formula:C14H23N7O6Purezza:98%Colore e forma:SolidPeso molecolare:385.38IKK2-IN-4
CAS:IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-α in PBMC induced by LPS.Formula:C12H11N3O2SPurezza:99.83%Colore e forma:SolidPeso molecolare:261.3Ref: TM-T36524
1mg108,00€5mg261,00€10mg401,00€25mg622,00€50mg837,00€100mg1.125,00€200mg1.504,00€500µg82,00€HSP90-IN-13
CAS:HSP90-IN-13 (5k): potent HSP90 inhibitor, IC50 25.07 nM, targets EGFR/VEGFR-2/Topo-2, blocks MCF-7 G2/M cycle, induces apoptosis.Formula:C26H21N5O3SColore e forma:SolidPeso molecolare:483.54PDGFR-IN-1
CAS:PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.Formula:C25H30N8OPurezza:99.13% - 99.49%Colore e forma:SolidPeso molecolare:458.56Ref: TM-T62872
1mg170,00€5mg432,00€10mg655,00€25mg1.153,00€50mg1.665,00€100mg2.250,00€1mL*10mM (DMSO)434,00€NSC745885
CAS:NSC745885, Antitumor agent, downregulates EZH2 via proteasomal degradation, toxic to drug-resistant cancer lines, for bladder and oral cancer.Formula:C14H6N2O2SPurezza:98%Colore e forma:SolidPeso molecolare:266.27BRD4 Inhibitor-15
CAS:BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.Formula:C22H21N3O2Colore e forma:SolidPeso molecolare:359.42bpV(phen)
CAS:bpV(phen) is a potent protein tyrosine phosphatase (PTP) and PTEN inhibitor (IC50s: 343 nM, 920 nM, and 38 nM for PTP-β, PTP-1B, and PTEN).Formula:C12H8KN2O5VPurezza:98%Colore e forma:SolidPeso molecolare:350.24IHMT-TRK-284
CAS:IHMT-TRK-284: Oral type II TRK inhibitor; targets TRKA, TRKB, TRKC (IC50s: 10.5, 0.7, 2.6 nM); selective and anti-tumor effective.Formula:C25H27N7OSColore e forma:SolidPeso molecolare:473.59OXPHOS-IN-1
CAS:OXPHOS-IN-1 inhibits oxidative phosphorylation; halts MIA PaCa-2 (IC50: 2.34 μM) and BxPC-3 cells growth (IC50: 13.82 μM).Formula:C19H29N3O6S2Colore e forma:SolidPeso molecolare:459.58TRK-IN-23
CAS:TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,Formula:C20H17FN4O2Purezza:98%Colore e forma:SolidPeso molecolare:364.37S116836
CAS:S116836 is a tyrosine kinase inhibitor.Formula:C27H21F3N6OPurezza:98%Colore e forma:SolidPeso molecolare:502.49Apoptosis inducer 10
CAS:Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity.Formula:C27H46N2O2Colore e forma:SolidPeso molecolare:430.67DBIBB
CAS:DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.Formula:C23H20N2O6SPurezza:98.49% - 99.1%Colore e forma:SolidPeso molecolare:452.48Ref: TM-T22070
1mg42,00€5mg93,00€10mg134,00€25mg264,00€50mg378,00€100mg553,00€500mg1.111,00€1mL*10mM (DMSO)93,00€IDO1/TDO-IN-1
CAS:IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.Formula:C21H16O6Colore e forma:SolidPeso molecolare:364.35EGFR-IN-60
CAS:EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.Formula:C28H28Cl2N6OColore e forma:SolidPeso molecolare:535.47Mcl1-IN-9
CAS:Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.Formula:C37H39ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:639.18Antioxidant agent-5
CAS:Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.Formula:C24H24N6OColore e forma:SolidPeso molecolare:412.49S65487
CAS:S65487 (VOB560) inhibits Bcl-2, including G101V and D103Y variants, while sparing MCL-1, BFL-1, and BCL-XL, supporting its anticancer potential.Formula:C41H41ClN6O4Purezza:99.034%Colore e forma:SolidPeso molecolare:717.26LLP-3
CAS:Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.Formula:C32H23ClN2O4Colore e forma:SolidPeso molecolare:534.99c-Met-IN-14
CAS:c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.Formula:C34H38ClFN4O7SColore e forma:SolidPeso molecolare:701.2Anticancer agent 83
CAS:Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.Formula:C20H19N5OSColore e forma:SolidPeso molecolare:377.46AV123
CAS:AV123, a RIPK1 inhibitor, non-cytotoxic, IC50: 12.12 μM; blocks TNF-α necroptosis (EC50: 1.7 μM) not apoptosis; useful in necrosis-related disease studies.Formula:C11H14N4O2Colore e forma:SolidPeso molecolare:234.25Anisperimus
CAS:Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.
Formula:C18H39N7O3Purezza:98.10%Colore e forma:SolidPeso molecolare:401.55SZM679
SZM679: Oral RIPK1 inhibitor, Kd 8.6 nM, weak RIPK3 affinity (>5000 nM). Reduces inflammation, Tau phosphorylation in AD research.Formula:C27H18F5N3O5SPurezza:98%Colore e forma:SolidPeso molecolare:591.51Docetaxel trihydrate
CAS:Docetaxel trihydrate (RP-56976 Trihydrate) is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis.Formula:C43H59NO17Purezza:98.68% - >99.99%Colore e forma:White Crystalline PowderPeso molecolare:861.95Bcl-2/Mcl-1-IN-2
CAS:Bcl-2/Mcl-1-IN-2 is a Bcl-2 (Ki: 4.70 μM) and Mcl-1 (Ki: 0.88 μM) inhibitor.Bcl-2/Mcl-1-IN-2 can be used in cancer research.Formula:C26H24ClNO3Colore e forma:SolidPeso molecolare:433.93LY5
CAS:LY5 is an inhibitor of STAT3 that acts by inhibiting cell viability, cell migration, and angiogenesis in medulloblastoma cells.Formula:C15H11N3O4SPurezza:98%Colore e forma:SolidPeso molecolare:329.33GW-3333
CAS:GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.Formula:C22H36N4O4Purezza:98%Colore e forma:SolidPeso molecolare:420.55PI3K/Akt/mTOR-IN-3
CAS:PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.Formula:C34H51NO2Colore e forma:SolidPeso molecolare:505.77HDAC1/2 and CDK2-IN-1
CAS:Compound 14d inhibits HDAC1 (IC50=70.7μM), HDAC2 (23.1μM), CDK2 (0.80μM), blocks cell cycle, induces apoptosis, and shows in vivo anti-tumor effects.Formula:C26H22ClN7OColore e forma:SolidPeso molecolare:483.95Nampt-IN-8
CAS:Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.Formula:C36H35N3O4Colore e forma:SolidPeso molecolare:573.68NVX-207
CAS:NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.Formula:C36H59NO6Purezza:98%Colore e forma:SolidPeso molecolare:601.86Polyphyllin II
CAS:Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.Formula:C44H70O16Purezza:99.92%Colore e forma:SolidPeso molecolare:855.02Ref: TM-T3894
2mg38,00€5mg55,00€10mg93,00€25mg137,00€50mg188,00€100mg283,00€200mg437,00€1mL*10mM (DMSO)88,00€BI-0282
CAS:BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.Formula:C30H23Cl2FN4O4Colore e forma:SolidPeso molecolare:593.43S130
CAS:S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.Formula:C24H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.47SD-36
CAS:SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.Formula:C59H62F2N9O12PPurezza:98% - >99.99%Colore e forma:SoildPeso molecolare:1158.15HLI 373
CAS:HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.Formula:C18H23N5O2Colore e forma:SolidPeso molecolare:341.41Misetionamide
CAS:Misetionamide: Oral oxathiazin-like, GAPDH inhibitor with anticancer properties for research use.Formula:C3H7NO3SPurezza:99.65%Colore e forma:SolidPeso molecolare:137.16Ref: TM-T72879
1mgPrezzo su richiesta5mgPrezzo su richiesta10mgPrezzo su richiesta25mg1.324,00€50mg1.783,00€100mg2.250,00€1mL*10mM (DMSO)Prezzo su richiestaMSN-50
CAS:MSN-50, an inhibitor of Bax and Bak oligomerization, inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection.Formula:C36H38BrN3O6Colore e forma:SolidPeso molecolare:688.61PDE4-IN-10
CAS:PDE4-IN-10 (7a), potent PDE4B inhibitor, IC50 7.01μM; selective, stable, TNF-α blocking, non-toxic in vitro.Formula:C18H13NColore e forma:SolidPeso molecolare:243.3Erbstatin
CAS:Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.Formula:C9H9NO3Colore e forma:SolidPeso molecolare:179.17PARP-1-IN-2
CAS:PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM).PARP-1-IN-2 showed significant antiproliferative activity against
Formula:C22H15Cl2N3O2Purezza:98.82%Colore e forma:SolidPeso molecolare:424.28PD-1/PD-L1-IN-NP19
CAS:PD-1/PD-L1-IN-NP19: a PD-1/PD-L1 inhibitor with 12.5 nM IC50, may boost antitumor immunity.Formula:C33H31ClN2O4Purezza:96.70%Colore e forma:SolidPeso molecolare:555.06RIP2 Kinase Inhibitor 3
CAS:RIP2 Kinase Inhibitor 3 is a potent and selective inhibitor of RIP2 with an IC50 of 1 nM.Formula:C19H24N4O3SPurezza:99.32% - 99.52%Colore e forma:SolidPeso molecolare:388.48Dinoprost
CAS:Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.Formula:C20H34O5Purezza:97.94% - 98.04%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:354.48Ref: TM-T15133
5mg49,00€10mg74,00€25mg137,00€50mg205,00€100mg326,00€200mg485,00€1mL*10mM (DMSO)54,00€Quinate
CAS:Quinate: oral antiarrhythmic, inhibits P450db, blocks K+ channels (IC50 19.9 μM), used in malaria research.Formula:C26H36N2O9Colore e forma:SolidPeso molecolare:520.579CAY10747
CAS:CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.Formula:C42H48FNO6Colore e forma:SolidPeso molecolare:681.83Verrucarin J
CAS:Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.54Caspase-9 Inhibitor III
CAS:Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.Formula:C24H35ClN6O9Colore e forma:SolidPeso molecolare:587.02PI3Kδ-IN-10
CAS:PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).Formula:C19H16ClN9Colore e forma:SolidPeso molecolare:405.84Anticancer agent 59
Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.Formula:C42H59NO6Colore e forma:SolidPeso molecolare:673.92MPT0B392
CAS:MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.Formula:C19H20N2O6SColore e forma:SolidPeso molecolare:404.44PBENZ-DBRMD
CAS:PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.Formula:C11H5Br2NO4Colore e forma:SolidPeso molecolare:374.97PD-1-IN-22
CAS:PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of 92.3 nM).Formula:C25H25N5O4Purezza:99.51%Colore e forma:SolidPeso molecolare:459.5Ref: TM-T12379
1mg109,00€2mg163,00€5mg243,00€10mg355,00€25mg532,00€50mg750,00€100mg1.009,00€500mg2.035,00€1mL*10mM (DMSO)284,00€2,5-Dihydroxybiphenyl
CAS:2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.
Formula:C12H10O2Purezza:99.66%Colore e forma:White To Grey-Brownish PowderPeso molecolare:186.21Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Formula:C29H39BrFN3O5Purezza:98%Colore e forma:SolidPeso molecolare:608.54STAT5-IN-2
CAS:STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively).Formula:C26H27N3OPurezza:99.55%Colore e forma:SolidPeso molecolare:397.51Ref: TM-T16940
1mg58,00€5mg110,00€10mg182,00€25mg289,00€50mg399,00€100mg530,00€200mg717,00€1mL*10mM (DMSO)122,00€Erasin
Erasin is a STAT3 inhibitor induces apoptosis in various cancer cell lines (e.g., MDA-MB-231, HCC-827) and against Erlotinib-resistant cancer cells.Formula:C20H19N3O3Colore e forma:SolidPeso molecolare:349.38Declopramide
CAS:Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.Formula:C13H20ClN3OPurezza:98.53%Colore e forma:SolidPeso molecolare:269.77Prexasertib mesylate
CAS:Prexasertib (LY2606368), a Chk1/2 inhibitor, enhances therapy in acute lymphoblastic leukemia, causing DNA damage and antitumor effects.Formula:C19H23N7O5SPurezza:98%Colore e forma:SolidPeso molecolare:461.49Topoisomerase I inhibitor 3
CAS:Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.Formula:C18H14FNO3Colore e forma:SolidPeso molecolare:311.31Tubulin inhibitor 30
CAS:Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.Formula:C22H19N3O5Colore e forma:SolidPeso molecolare:405.4ABT-100
CAS:ABT-100 is a potent, highly selective, and orally active farnesyl transferase inhibitor with broad-spectrum antitumor activity.Formula:C27H19F3N4O3Purezza:98%Colore e forma:SolidPeso molecolare:504.46α-NETA
CAS:α-NETA is a ChA inhibitor and an ALDH1A1 and CMKLR1 antagonist with anticancer activity and inhibits cholinesterase and acetylcholinesterase (AChE).Formula:C16H20INOPurezza:99.54%Colore e forma:SolidPeso molecolare:369.24
