Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(6 prodotti)
- BCL(11 prodotti)
- Caspasi(125 prodotti)
- FOXO1(3 prodotti)
- IAP(66 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(125 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(15 prodotti)
- Survivin(13 prodotti)
- TNF(92 prodotti)
- c-RET(51 prodotti)
- p53(62 prodotti)
Mostrare 6 più sottocategorie
Trovati 5593 prodotti di "Apoptosi"
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SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Formula:C28H30ClN5O4SPurezza:98.62% - 99.53%Colore e forma:Orange PowderPeso molecolare:568.09Dibenz[a,h]anthracene
CAS:<p>Dibenz[a,h]anthracene (CCRIS 208) has induced DNA damage and gene mutations in bacteria and gene mutations and transformation in several types of mammalian cell</p>Formula:C22H14Purezza:99.97%Colore e forma:Colorless Plates Or Leaflets /Recrystallized/ From Acetic Acid Physical Description White Crystals Or Pale Yellow Solid Sublimes (Ntp 1992)Peso molecolare:278.35Camptothecin
CAS:<p>Camptothecin (CPT) belongs to the alkaloid group of natural products and is a specific DNA topoisomerase I (Topo I) inhibitor (IC50=679 nM) with specificity.</p>Formula:C20H16N2O4Purezza:99.52% - 99.88%Colore e forma:Solid PowderPeso molecolare:348.35NPB
CAS:<p>NPB (Alpha-NPB) is a potent BAD phosphorylation inhibitor(at Ser99,IC50 of 0.41 μM.)</p>Formula:C29H31Cl2N3O2Purezza:99.93%Colore e forma:SolidPeso molecolare:524.48SAR405838
CAS:<p>MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.</p>Formula:C29H34Cl2FN3O3Purezza:98.63%Colore e forma:SolidPeso molecolare:562.5L-Cystathionine
CAS:<p>L-Cystathionine: nonprotein amino acid; important for sulfur amino acid metabolism; used in cardiovascular research.</p>Formula:C7H14N2O4SPurezza:96.43% - >99.99%Colore e forma:SolidPeso molecolare:222.26S116836
CAS:<p>S116836 is a tyrosine kinase inhibitor.</p>Formula:C27H21F3N6OPurezza:98%Colore e forma:SolidPeso molecolare:502.49Undecylprodigiosin
CAS:<p>Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.</p>Formula:C25H35N3OColore e forma:SolidPeso molecolare:393.56PD-1/PD-L1-IN-20
CAS:<p>PD-1/PD-L1-IN-20 is a small molecule inhibitor of PD-1/PD-L1 protein-protein interaction.</p>Formula:C30H26BrClN2O3Colore e forma:SolidPeso molecolare:577.9CT1-3
CAS:<p>CT1-3 is a potent anti-cancer compound targeting JNK/Bcl-2 pathways, blocking EMT in HCCs, and is non-toxic to liver/kidneys in mice.</p>Formula:C25H29NO3S2Colore e forma:SolidPeso molecolare:455.63HI5
CAS:<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Formula:C42H43N5O8Colore e forma:SolidPeso molecolare:745.82PDPOB
CAS:<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Formula:C15H20O5Colore e forma:SolidPeso molecolare:280.32GLS1 Inhibitor-4
CAS:<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Formula:C29H27F3N10O2S2Purezza:98%Colore e forma:SolidPeso molecolare:668.72VEGFR-2-IN-23
CAS:<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Formula:C22H15N5O2Colore e forma:SolidPeso molecolare:381.39MPT0B214
CAS:<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Formula:C20H20N2O5Colore e forma:SolidPeso molecolare:368.38PD-1/PD-L1-IN-29
CAS:<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Formula:C26H24N2O6Colore e forma:SolidPeso molecolare:460.48CYD-2-11
CAS:<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Formula:C22H18N2O3Colore e forma:SolidPeso molecolare:358.39RIPK1-IN-13
CAS:<p>RIPK1-IN-13 inhibits RIPK1 (IC50=1139 nM), potentially blocking necrosis and treating inflammation.</p>Formula:C21H20ClN3O3Colore e forma:SolidPeso molecolare:397.85CT-1
CAS:<p>CT-1 is a DNA minor groove ligand and causes p53-dependent breast cancer cell apoptosis.</p>Formula:C29H23F3N4OPurezza:99.79%Colore e forma:SolidPeso molecolare:500.51PD173952
CAS:<p>PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.</p>Formula:C24H21Cl2N5O2Purezza:99.5%Colore e forma:SolidPeso molecolare:482.36PI3K inhibitor C 96
CAS:<p>PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.</p>Formula:C11H8N2O3SPurezza:98%Colore e forma:SolidPeso molecolare:248.26p53 Activator 5
CAS:<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Formula:C29H32F6N4OColore e forma:SolidPeso molecolare:566.58MMP2-IN-1
CAS:<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Formula:C15H13NO5SColore e forma:SolidPeso molecolare:319.33RO2468
CAS:<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Formula:C30H30Cl2FN5O4Purezza:98%Colore e forma:SolidPeso molecolare:614.49TH-Z835
CAS:<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Formula:C30H38N6OPurezza:98%Colore e forma:SolidPeso molecolare:498.66ZC0101
CAS:<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Formula:C17H15N3O2Colore e forma:SolidPeso molecolare:293.32EGFR-IN-60
CAS:<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Formula:C28H28Cl2N6OColore e forma:SolidPeso molecolare:535.47BLM-IN-2
<p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>Formula:C33H38BrFN4OColore e forma:SolidPeso molecolare:605.58SIRT6 activator 12q
CAS:<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Formula:C31H22N2O2Colore e forma:SolidPeso molecolare:454.52CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Formula:C35H53N7O7Colore e forma:SolidPeso molecolare:683.84SKLB0565
CAS:<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Formula:C20H25ClN6OColore e forma:SolidPeso molecolare:400.91Mcl1-IN-3
CAS:<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Formula:C27H22ClN3O4Purezza:98%Colore e forma:SolidPeso molecolare:487.93Mcl1-IN-11
CAS:<p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>Formula:C38H41N3O5S2Purezza:98%Colore e forma:SolidPeso molecolare:683.88TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Formula:C20H21N5OSColore e forma:SolidPeso molecolare:379.48GGTI-2154
CAS:<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Formula:C24H28N4O3Colore e forma:SolidPeso molecolare:420.5Bcl-2/Mcl-1-IN-3
CAS:<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Formula:C27H26ClNO4Colore e forma:SolidPeso molecolare:463.95Anticancer agent 56
CAS:<p>Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>Formula:C20H18ClN3O3Colore e forma:SolidPeso molecolare:383.83(S)-Erypoegin K
CAS:<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Formula:C20H18O6Colore e forma:SolidPeso molecolare:354.35(Rac)-Indoximod
CAS:<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Formula:C12H14N2O2Colore e forma:SolidPeso molecolare:218.25AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Formula:C17H15N5SColore e forma:SolidPeso molecolare:321.4Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Formula:C31H34Cl2N6O3P2RuColore e forma:SolidPeso molecolare:772.56Anisperimus
CAS:<p>Anisperimus (LF 15-0195) is an immunosuppressant that prevents CNS autoimmunity by promoting the development of regulatory CD4 T cells expressing Foxp3.</p>Formula:C18H39N7O3Purezza:98.10%Colore e forma:SolidPeso molecolare:401.55CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Formula:C14H15NO4Purezza:98%Colore e forma:SolidPeso molecolare:261.27PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Formula:C20H22N6O4Purezza:98%Colore e forma:SolidPeso molecolare:410.43ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Formula:C24H32N4O3Colore e forma:SolidPeso molecolare:424.54Topoisomerase II inhibitor 11
CAS:<p>Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).</p>Formula:C27H21BrCl2N2O2SColore e forma:SolidPeso molecolare:588.34Antitumor agent-56
CAS:<p>Antitumor-56: Oral triptolide derivative; inhibits melanoma; anti-tumor, anti-inflammatory, NO-releasing properties.</p>Formula:C28H28N2O10SColore e forma:SolidPeso molecolare:584.59CX-5011
CAS:<p>CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].</p>Formula:C20H12N4O2Purezza:98%Colore e forma:SolidPeso molecolare:340.33CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Formula:C16H12N2O4S3Purezza:98%Colore e forma:SolidPeso molecolare:392.47PD-1/PD-L1-IN 5
CAS:<p>PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).</p>Formula:C22H18N4O3SColore e forma:SolidPeso molecolare:418.47Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Formula:C20H18O5Colore e forma:SolidPeso molecolare:338.35Mps1-IN-5
CAS:<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Formula:C24H25N9Colore e forma:SolidPeso molecolare:439.52GK563
CAS:<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Formula:C16H22O2Colore e forma:SolidPeso molecolare:246.34Caspase-3/7 activator 2
<p>Caspase-3/7 activator 2 triggers apoptosis with tumor selectivity and anti-proliferative properties.</p>Formula:C32H34N2O7Colore e forma:SolidPeso molecolare:558.62Jolkinolide B
CAS:<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Formula:C20H26O4Purezza:99.39% - 99.7%Colore e forma:SolidPeso molecolare:330.42(Z)-4EGI-1
CAS:<p>(Z)-4EGI-1, a Z-isomer, inhibits eIF4E/eIF4G; binds eIF4E (IC50=43.5 μM, Kd=8.74 μM); anticancer properties.</p>Formula:C18H12Cl2N4O4SColore e forma:SolidPeso molecolare:451.28TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Formula:C18H9Cl4N5OColore e forma:SolidPeso molecolare:453.11Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Formula:C26H23NOColore e forma:SolidPeso molecolare:365.47Anticancer agent 47
CAS:<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Formula:C19H14N2O4SColore e forma:SolidPeso molecolare:366.39CAY10747
CAS:<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Formula:C42H48FNO6Colore e forma:SolidPeso molecolare:681.83PD1-PDL1-IN 1
CAS:<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Formula:C14H23N7O6Purezza:98%Colore e forma:SolidPeso molecolare:385.38FAK-IN-5
CAS:<p>FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.</p>Formula:C29H29ClF3N3O4Colore e forma:SolidPeso molecolare:576.01Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Formula:C22H19N3O5Colore e forma:SolidPeso molecolare:405.4Lexibulin dihydrochloride
CAS:<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Formula:C24H32Cl2N6O2Purezza:98%Colore e forma:SolidPeso molecolare:507.46YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Formula:C24H24N6OColore e forma:SolidPeso molecolare:412.49SPRC
CAS:<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Formula:C6H9NO2SPurezza:98%Colore e forma:SolidPeso molecolare:159.21EGFR-IN-52
CAS:<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Formula:C19H18N4O3SColore e forma:SolidPeso molecolare:382.44Anticancer agent 67
CAS:<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Formula:C26H24F2N6O2S2Colore e forma:SolidPeso molecolare:554.63Quinidine Monosulfate
CAS:<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Formula:C40H50N4O8SColore e forma:SolidPeso molecolare:746.92Topoisomerase I inhibitor 3
CAS:<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Formula:C18H14FNO3Colore e forma:SolidPeso molecolare:311.31DAT-230
CAS:<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Formula:C20H21NO2SColore e forma:SolidPeso molecolare:339.45RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Formula:C32H33FN6O4Colore e forma:SolidPeso molecolare:584.64Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Formula:C28H28N2O2Colore e forma:SolidPeso molecolare:424.53UCD38B HCl
CAS:<p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>Formula:C15H17Cl2N7O3Purezza:98%Colore e forma:SolidPeso molecolare:414.25TJ08
CAS:<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Formula:C22H16FN3O4Purezza:99.89%Colore e forma:SolidPeso molecolare:405.38EP12
CAS:<p>EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by</p>Formula:C26H22FN3O2Purezza:98%Colore e forma:SolidPeso molecolare:427.47Telomerase-IN-4
CAS:<p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>Formula:C21H18N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:406.52Ac-IETD-CHO
CAS:<p>Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure.</p>Formula:C21H34N4O10Purezza:98%Colore e forma:SolidPeso molecolare:502.52Telomerase-IN-5
CAS:<p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>Formula:C22H20N4OS2Purezza:98%Colore e forma:SolidPeso molecolare:420.55TRAF-STOP inhibitor 6877002
CAS:<p>TRAF-STOP 6877002 inhibits CD40-TRAF6, curbing leukocyte recruitment and macrophage activation/proliferation in plaques.</p>Formula:C17H17NOPurezza:99.76%Colore e forma:SolidPeso molecolare:251.32TL02-59 dihydrochloride
CAS:<p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>Formula:C32H36Cl2F3N5O4Purezza:98%Colore e forma:SolidPeso molecolare:682.56PERK-IN-3
CAS:<p>PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).</p>Formula:C22H16F2N4O2Purezza:98%Colore e forma:SolidPeso molecolare:406.38Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Formula:C29H34N2O15Colore e forma:SolidPeso molecolare:650.58STAT3-IN-3
CAS:<p>STAT3-IN-3 is a potent and selective signal transducer inhibitor and transcription 3 (STAT3) activator.</p>Formula:C27H26BrN3O6SPurezza:98%Colore e forma:SolidPeso molecolare:600.483-(3-Phenoxybenzyl)amino-β-carboline
CAS:<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Formula:C24H19N3OColore e forma:SolidPeso molecolare:365.43RIP1 kinase inhibitor 5
CAS:<p>RIP1 kinase inhibitor 5 (example 1) serves as a potent regulator of tumor immunity by inhibiting RIP1, functioning similarly to SIR1-365 (compound 13) in</p>Formula:C13H17F2NO2Purezza:98%Colore e forma:SolidPeso molecolare:257.28EGFR-IN-51
CAS:<p>EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.</p>Formula:C21H15N3O2SColore e forma:SolidPeso molecolare:373.43AP1867
CAS:<p>AP1867 is a synthetic FKBP12F36V-directed ligand.</p>Formula:C38H47NO11Colore e forma:SolidPeso molecolare:693.78Ormeloxifene
CAS:estrogen receptor modulatorFormula:C30H35NO3Purezza:98%Colore e forma:SolidPeso molecolare:457.6Fenoldopam hydrochloride
CAS:<p>Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.</p>Formula:C16H17Cl2NO3Colore e forma:SolidPeso molecolare:342.22IMM-H004
CAS:<p>IMM-H004 is an effective inhibitor of BV2 microglia activation.</p>Formula:C16H20N2O4Purezza:98%Colore e forma:SolidPeso molecolare:304.34Antitumor agent-53
CAS:<p>Antitumor agent-53 hinders tumor growth, induces G2/M cell cycle arrest, and triggers apoptosis via PI3K/AKT in HGC-27 cells.</p>Formula:C24H18FN3OColore e forma:SolidPeso molecolare:383.42PTG-0861
CAS:<p>PTG-0861 is a selective HDAC6 inhibitor with an IC50 of 5.92 nm, promising for hematological cancer research.</p>Formula:C15H9F5N2O3Colore e forma:SolidPeso molecolare:360.24RETRA
CAS:<p>RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.</p>Formula:C11H12BrNO3S2Purezza:98%Colore e forma:SolidPeso molecolare:350.25SB 706504
CAS:<p>SB 706504 is an effective p38 MAPK inhibitor that suppresses inflammatory gene expression in macrophages and inhibits TNFα production in COPD.</p>Formula:C24H19F3N8OPurezza:98.686%Colore e forma:SolidPeso molecolare:492.46SHP2-IN-8
CAS:<p>SHP2-IN-8: reversible, selective SHP2 inhibitor; IC50=23 nM; induces AKT dephosphorylation and Hela cell apoptosis.</p>Formula:C17H21Cl2N5SColore e forma:SolidPeso molecolare:398.35Flupenthixol
CAS:<p>Flupentixol is a typical antipsychotic drug of the thioxanthene class. Flupentixol is also used in low doses as an antidepressant.</p>Formula:C23H25F3N2OSPurezza:98%Colore e forma:SolidPeso molecolare:434.52HDAC-IN-39
CAS:<p>HDAC-IN-39 inhibits HDAC1-3 (IC50: 1.07-2.27 μM), arrests G2/M phase, hinders microtubule polymerization, and is effective against drug-resistant cancers.</p>Formula:C27H26N4O4SColore e forma:SolidPeso molecolare:502.58BMS-1166 hydrochloride
CAS:<p>"Motixafortide blocks CXCR4 with 1 nM potency. BMS-1166 hinders PD-1/PD-L1, boosting T cell activation, IC50: 1.4 nM."</p>Formula:C36H34Cl2N2O7Purezza:98%Colore e forma:SolidPeso molecolare:677.57IV-23
CAS:<p>IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.</p>Formula:C18H18BrNO4Purezza:98%Colore e forma:SolidPeso molecolare:392.24HS56
CAS:<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Formula:C13H8ClN5OSColore e forma:SolidPeso molecolare:317.75VEGFR-2-IN-19
CAS:<p>VEGFR-2-IN-19 (15b) effectively inhibits VEGFR2, induces apoptosis, and increases oxidative stress, showing potential as an anticancer drug.</p>Formula:C21H19N3O2Colore e forma:SolidPeso molecolare:345.39SKF1
CAS:<p>SKF1 inhibits FK506, stunts cell growth in high NaCl, kills cells in low salt, and targets yeast mitochondria.</p>Formula:C23H37ClN2O2Purezza:98%Colore e forma:SolidPeso molecolare:409.01D-Cl-amidine
CAS:<p>D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.</p>Formula:C14H19ClN4O2Purezza:98%Colore e forma:SolidPeso molecolare:310.78RDR03871
CAS:<p>RDR03871 is an MDM2 inhibitor.</p>Formula:C18H16ClF3N6Purezza:97.78%Colore e forma:SolidPeso molecolare:408.81Mcl1-IN-4
CAS:Mcl1-IN-4 is an inhibitor of Mcl1 ( IC50:0.2 μM).Formula:C28H26N2O5SPurezza:98%Colore e forma:SolidPeso molecolare:502.58DC-CPin711
CAS:<p>DC-CPin711: Potent, selective CBP bromodomain inhibitor, IC50=0.0626 μM; arrests G1 cell cycle, induces apoptosis.</p>Formula:C23H22N4O2Colore e forma:SolidPeso molecolare:386.45(R)-STU104
CAS:<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Formula:C18H18O4Purezza:98.91% - 99.42%Colore e forma:SolidPeso molecolare:298.33SMBA1
CAS:<p>SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.</p>Formula:C20H13NO3Purezza:99.2%Colore e forma:SolidPeso molecolare:315.32PI3K/AKT-IN-2
CAS:<p>PI3K/AKT-IN-2 inhibits PI3K/AKT, EMT, induces apoptosis, and blocks tubulin polymerization.</p>Formula:C32H27BrO10Colore e forma:SolidPeso molecolare:651.45GRI977143
CAS:<p>GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.</p>Formula:C22H17NO4SPurezza:98.07%Colore e forma:SolidPeso molecolare:391.44Flonoltinib
CAS:<p>Flonoltinib (JAK2/FLT3-IN-1) is an orally active and efficient JAK2/FLT3 inhibitor with anti-cancer properties.</p>Formula:C25H34FN7OPurezza:99.52%Colore e forma:SolidPeso molecolare:467.58Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Formula:C32H36N10O2Purezza:98%Colore e forma:SolidPeso molecolare:592.69Cinnabarinic acid
CAS:<p>mGlu4 receptor agonist</p>Formula:C14H8N2O6Purezza:98%Colore e forma:SolidPeso molecolare:300.22CEP-40125
CAS:<p>CEP-40125 (RXDX-107) is a DNA alkylating agent for the study of advanced solid tumors.</p>Formula:C28H45Cl2N3O2Purezza:98.28%Colore e forma:SolidPeso molecolare:526.58Nampt-IN-3
CAS:<p>Nampt-IN-3 simultaneously inhibit nicotinamide phosphoribosyltransferase (NAMPT) and HDAC (IC50s of 31 nM and 55 nM, respectively).</p>Formula:C29H25N7O2Purezza:98%Colore e forma:SolidPeso molecolare:503.55S130
CAS:<p>S130 is a high affinity, selectiveATG4B (a major cysteine protease) inhibitor (IC50 of 3.24 μM).It suppresses autophagy flux.</p>Formula:C24H25N3O2Purezza:98%Colore e forma:SolidPeso molecolare:387.47Mcl1-IN-9
CAS:<p>Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.</p>Formula:C37H39ClN4O4Purezza:98%Colore e forma:SolidPeso molecolare:639.18Sparfosic Acid
CAS:<p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>Formula:C6H10NO8PPurezza:98.89%Colore e forma:SolidPeso molecolare:255.12KS106
CAS:<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Formula:C18H15BrF3N3O2SPurezza:99.31%Colore e forma:SolidPeso molecolare:474.3hCAIX-IN-12
CAS:<p>hCAIX-IN-12: hCAIX inhibitor; IC50: 0.74 μM (CAIX), 10.78 μM (CAII); impedes cell growth, triggers apoptosis, boosts ROS; potential in CRC research.</p>Formula:C18H14N4O3S2Colore e forma:SolidPeso molecolare:398.46SAR125844
CAS:<p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>Formula:C25H23FN8O2S2Purezza:98.73%Colore e forma:SolidPeso molecolare:550.63IST5-002
CAS:<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Formula:C17H20N5O7PPurezza:99.36%Colore e forma:SolidPeso molecolare:437.34Antitumor agent-45
CAS:<p>Antitumor agent-45 has an inhibitory effect on c-Met expression and is able to block A549 cells in the G0/G1 and G2/M phases and induce apoptosis.</p>Formula:C28H17BrFN5O3Colore e forma:SolidPeso molecolare:570.37Estramustine phosphate
CAS:<p>Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.</p>Formula:C23H32Cl2NO6PColore e forma:SolidPeso molecolare:520.38DRI-C21041
CAS:<p>DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, demonstrating an inhibitory concentration 50 (IC50) value of 0.31 μM.</p>Formula:C30H21N3O7SColore e forma:SolidPeso molecolare:567.57Apoptosis inducer 10
CAS:<p>Apoptosis inducer 10 is a potent apoptosis inducer with anti-proliferative activity.</p>Formula:C27H46N2O2Colore e forma:SolidPeso molecolare:430.67Nutlin-1
CAS:<p>Nutlin-1 is a p53-MDM2 binding inhibitor, p-Glycoprotein (p-gp) transport substrate, and antitumor agent.</p>Formula:C32H34Cl2N4O4Colore e forma:SolidPeso molecolare:609.54Nampt-IN-8
CAS:<p>Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.</p>Formula:C36H35N3O4Colore e forma:SolidPeso molecolare:573.68NVX-207
CAS:<p>NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.</p>Formula:C36H59NO6Purezza:98%Colore e forma:SolidPeso molecolare:601.86MBM-17S
CAS:<p>MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and</p>Formula:C36H40N6O10Purezza:98%Colore e forma:SolidPeso molecolare:716.74Anticancer agent 59
<p>Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.</p>Formula:C42H59NO6Colore e forma:SolidPeso molecolare:673.92FW1256
CAS:<p>FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.</p>Formula:C12H10NOPSColore e forma:SolidPeso molecolare:247.25Epinephrine bitartrate
CAS:<p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>Formula:C13H19NO9Purezza:98.6% - 99.07%Colore e forma:White SolidPeso molecolare:333.3Ro 31-7837
CAS:<p>Ro 31-7837 is an opener of potassium channel.</p>Formula:C17H16N2O2Colore e forma:SolidPeso molecolare:280.32EAPB 02303
CAS:<p>EAPB 02303, a microtubule inhibitor, induces mitotic arrest, spindle impairment, apoptosis, and has antitumor effects, enhancing Paclitaxel.</p>Formula:C17H14N4O2Colore e forma:SolidPeso molecolare:306.32HS-438
CAS:<p>HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.</p>Formula:C17H17N3O3SColore e forma:SolidPeso molecolare:343.4EGFR-IN-56
CAS:<p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>Formula:C23H22N4O3SColore e forma:SolidPeso molecolare:434.51ML132
CAS:<p>ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).</p>Formula:C22H28ClN5O5Colore e forma:SolidPeso molecolare:477.94Allethrin
CAS:<p>Allethrin induces oxidative stress, apoptosis and calcium release. Allethrin, a pyrethroid insecticide is a major mosquito repellent agent.</p>Formula:C19H26O3Purezza:99.52%Peso molecolare:302.41TH1834 dihydrochloride
CAS:<p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>Formula:C33H42Cl2N6O3Purezza:98%Colore e forma:SolidPeso molecolare:641.63W146 TFA
CAS:<p>W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.</p>Formula:C18H28F3N2O6PColore e forma:SolidPeso molecolare:456.399PARP14 inhibitor H10
CAS:<p>PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM</p>Formula:C24H27N7O7SPurezza:98%Colore e forma:SolidPeso molecolare:557.58EL-102
CAS:<p>EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.</p>Formula:C19H16N2O3S2Purezza:99.34%Colore e forma:SolidPeso molecolare:384.47EGFR-IN-46
CAS:<p>EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.</p>Formula:C27H32F3N3O3Colore e forma:SolidPeso molecolare:503.56Dinoprost
CAS:<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Formula:C20H34O5Purezza:97.94% - 98.04%Colore e forma:White To Off-White Crystalline SolidPeso molecolare:354.48QM31
CAS:<p>QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).</p>Formula:C39H38Cl4N4O4Purezza:98%Colore e forma:SolidPeso molecolare:768.56Dipin
CAS:<p>Dipin is an Antineoplastic.</p>Formula:C12H24N6O2P2Purezza:98%Colore e forma:SolidPeso molecolare:346.31Oxythiamine chloride HCl
CAS:<p>Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.</p>Formula:C12H17Cl2N3O2SColore e forma:SolidPeso molecolare:338.25Esuberaprost Sodium
CAS:<p>Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.</p>Formula:C23H27FN4O2Colore e forma:SolidPeso molecolare:410.48Vin-C01
CAS:<p>Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.</p>Formula:C20H24N2OColore e forma:SolidPeso molecolare:308.42MI-1061
CAS:<p>MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).</p>Formula:C30H26Cl2FN3O4Colore e forma:SolidPeso molecolare:582.45RIPK1-IN-15
CAS:<p>RIPK1-IN-15 (Compound 2.5) is a potent RIPK1 inhibitor that has the potential in neurodegenerative, autoimmune, and inflammatory diseases research [1].</p>Formula:C19H19N3O2Colore e forma:SolidPeso molecolare:321.37Verrucarin J
CAS:<p>Verrucarin J, a Myrothecium fungus metabolite, triggers apoptosis in some cancer cells and fights Candida, Mucor, and JUNV (IC50: 1.2 ng/mL).</p>Formula:C27H32O8Colore e forma:SolidPeso molecolare:484.54Declopramide
CAS:<p>Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.</p>Formula:C13H20ClN3OPurezza:98.53%Colore e forma:SolidPeso molecolare:269.77MI-389
CAS:<p>MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.</p>Formula:C35H35FN6O6Purezza:98.12%Colore e forma:SolidPeso molecolare:654.69PIK-C98
CAS:<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Formula:C16H10Cl2N2OSPurezza:98%Colore e forma:SolidPeso molecolare:349.23A-385358
CAS:<p>A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.</p>Formula:C32H41N5O5S2Purezza:99.97%Colore e forma:SolidPeso molecolare:639.83Rooperol
CAS:<p>Rooperol: a norlignan with p38α inhibiting, immunomodulatory, antitumor, antibacterial, anticonvulsant, and antioxidant properties.</p>Formula:C17H14O4Purezza:98%Colore e forma:SolidPeso molecolare:282.29AZM475271
CAS:<p>AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)</p>Formula:C23H27ClN4O3Purezza:99.78%Colore e forma:SolidPeso molecolare:442.94DC-5163
CAS:<p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>Formula:C18H20ClN3OSPurezza:98%Colore e forma:SolidPeso molecolare:361.89M199
CAS:<p>M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.</p>Formula:C17H17N3OPurezza:98%Colore e forma:SolidPeso molecolare:279.34MG-262
CAS:<p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>Formula:C25H42BN3O6Colore e forma:SolidPeso molecolare:491.43NHI-2
CAS:<p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>Formula:C17H12F3NO3Purezza:99.981%Colore e forma:SolidPeso molecolare:335.28MEB55
CAS:<p>MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Formula:C22H17NO4SPurezza:98%Colore e forma:SolidPeso molecolare:391.44Gea 3162
CAS:<p>GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.</p>Formula:C7H4Cl2N4OPurezza:98%Colore e forma:SolidPeso molecolare:231.04Dabuzalgron HCl
CAS:<p>Dabuzalgron, an adrenoceptor agonist, is used potentially for the treatment of urinary incontinence.</p>Formula:C12H17Cl2N3O3SPurezza:98%Colore e forma:SolidPeso molecolare:354.25ALC67
CAS:<p>ALC67, a novel 3-propionyl thiazolidine-4-carboxylic acid ethyl ester, activates caspase-9, showing potent anticancer properties.</p>Formula:C15H15NO3SPurezza:98%Colore e forma:SolidPeso molecolare:289.35L 741742 (free base)
CAS:<p>L 741742 is an effective and highly selective antagonist of the D4 dopamine receptor (Ki: 1700, 770, and 3.5 nM at cloned human D2, D3, and D4 receptors).</p>Formula:C23H25ClN2OPurezza:98%Colore e forma:SolidPeso molecolare:380.91BMH-9
CAS:<p>BMH-9 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.</p>Formula:C19H27N3O2Colore e forma:SolidPeso molecolare:329.44α-NETA
CAS:<p>α-NETA is a ChA inhibitor and an ALDH1A1 and CMKLR1 antagonist with anticancer activity and inhibits cholinesterase and acetylcholinesterase (AChE).</p>Formula:C16H20INOPurezza:99.54%Colore e forma:SolidPeso molecolare:369.24MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Formula:C35H49F2N7O4Purezza:98.77% - 99.99%Colore e forma:SolidPeso molecolare:669.8ATAD2-IN-1
CAS:<p>ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].</p>Formula:C22H26N6O5Colore e forma:SolidPeso molecolare:454.48Mitoguazone
CAS:<p>Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.</p>Formula:C5H12N8Purezza:97.47% - 98%Colore e forma:SolidPeso molecolare:184.2STK17A/B-IN-1
CAS:<p>STK17A/B-IN-1 (compound 9) is an orally active, potent, and selective inhibitor of STK17A/B, demonstrating an IC50 of 23 nM for STK17A. This compound is utilized in tumor research.</p>Formula:C26H27N7OColore e forma:SolidPeso molecolare:453.54DPBQ
CAS:<p>DPBQ (ZINC1620467) is a p53 activator.</p>Formula:C24H14N2O2Purezza:98.08%Colore e forma:SolidPeso molecolare:362.38Pracinostat dihydrochloride
CAS:<p>Pracinostat dihydrochloride is a highly effective histone deacetylase (HDAC) inhibitor with IC₅₀ values ranging from 40 to 140 nM, utilized in cancer research. Additionally, it inhibits metallo-β-lactamase domain-containing protein 2 (MBLAC2) hydrolase activity with an EC₅₀ of less than 10 nM.</p>Formula:C20H32Cl2N4O2Colore e forma:SolidPeso molecolare:431.40MeOIstPyrd
CAS:<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Formula:C14H16N4O2SColore e forma:SolidPeso molecolare:304.37Tubulin polymerization-IN-14
CAS:<p>Tubulin-IN-14 (20a) inhibits polymerization (IC50=3.15μM), has anti-cancer and anti-vascular effects, inducing cell death.</p>Formula:C15H15ClN2O2Colore e forma:SolidPeso molecolare:290.74YM-155 hydrochloride
CAS:<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Formula:C20H19ClN4O3Colore e forma:SolidPeso molecolare:398.85MI-3
CAS:<p>MI-3 (Menin-MLL Inhibitor) (Menin-MLL Inhibitor) is an effective inhibitor of Menin-MLL interaction (IC50: 648 nM).</p>Formula:C18H25N5S2Purezza:98.66% - 99.61%Colore e forma:SolidPeso molecolare:375.55(rel)-Oxaliplatin
CAS:<p>(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.</p>Formula:C8H14N2O4PtColore e forma:SolidPeso molecolare:397.29Vin-F03
CAS:<p>Vin-F03 protects pancreatic β-cells in type 2 diabetes research with an EC50 of 0.27 μM and prevents STZ-induced apoptosis.</p>Formula:C22H29N3Colore e forma:SolidPeso molecolare:335.49VEGFR-2-IN-22
CAS:<p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>Formula:C26H24ClFN4O6Colore e forma:SolidPeso molecolare:542.94Luxeptinib
CAS:<p>Luxeptinib (CG-806) is an oral, non-covalent pan-FLT3/BTK inhibitor for acute myeloid leukemia.</p>Formula:C25H17F4N5O2Colore e forma:SolidPeso molecolare:495.43OT-82
CAS:<p>OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.</p>Formula:C26H21FN4OPurezza:98.91% - 99.315%Colore e forma:SolidPeso molecolare:424.47MIR96-IN-1
CAS:<p>MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.</p>Formula:C33H48N8O2Colore e forma:SolidPeso molecolare:588.79PARP-2-IN-3
CAS:<p>PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.</p>Formula:C20H20ClN3O3Purezza:99.33%Colore e forma:SolidPeso molecolare:385.84MDM2/XIAP-IN-2
CAS:<p>MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).</p>Formula:C29H32N2O4SColore e forma:SolidPeso molecolare:504.64Mitochonic Acid 35
CAS:<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Formula:C19H19NO5Purezza:98%Colore e forma:SolidPeso molecolare:341.36CB-64D
CAS:<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Formula:C22H23NO2Colore e forma:SolidPeso molecolare:333.42FL3
CAS:<p>FL3 is a novel potent eIF4F inhibitor, it induces the death of cancer cells by an original mechanism that involves the apoptosis-inducing factor and caspase 12.</p>Formula:C25H23BrO5Colore e forma:SolidPeso molecolare:483.35Verticillin A
CAS:<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Formula:C30H28N6O6S4Purezza:98%Colore e forma:SolidPeso molecolare:696.84SK-7041
CAS:<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Formula:C19H21N3O3Purezza:98%Colore e forma:SolidPeso molecolare:339.39GW-3333
CAS:<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Formula:C22H36N4O4Purezza:98%Colore e forma:SolidPeso molecolare:420.55hGGPPS-IN-2
CAS:<p>hGGPPS-IN-2, a C2-ThP-BP analogue, inhibits hGGPPS, targets MM cells, induces apoptosis, and has anti-myeloma effects.</p>Formula:C20H18FN5O7P2SColore e forma:SolidPeso molecolare:553.4HDAC-IN-42
CAS:<p>HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.</p>Formula:C20H15NO7Colore e forma:SolidPeso molecolare:381.34Ki23057
CAS:<p>Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.</p>Formula:C30H35N3O4Colore e forma:SolidPeso molecolare:501.62PDGFR-IN-1
CAS:<p>PDGFR-IN-1 is a platelet-derived growth factor receptor (PDGFR) inhibitor, strongly inhibiting PDGFRα and PDGFRβ, useful for studying solid tumors.</p>Formula:C25H30N8OPurezza:99.13% - 99.49%Colore e forma:SolidPeso molecolare:458.56LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Formula:C28H42O5Colore e forma:SolidPeso molecolare:458.63
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