Apoptosi

Cetrelimab (JNJ 63723283) is a humanized monoclonal antibody targeting PD-1, useful in research on multiple myeloma and bladder cancer.

Orlistat (Tetrahydrolipstatin) is a lipase inhibitor and a FASN inhibitor. Orlistat has been shown to promote weight loss. Cost effective and quality assured.

Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.

BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.

Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and

Deferoxamine Mesylate (DFOM) is an iron chelator and iron death inhibitor.

Acesulfame potassium is a non-nutritive sweetener.

Chlorhexidine diacetate (Bactigras) is a disinfectant and topical anti-infective agent used also as mouthwash to prevent oral plaque.

Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.

Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.

LAT1-IN-1 (BCH) is a selective and competitive inhibitor of L-type amino acid transporter protein 1 (LAT1). LAT1-IN-1 has antitumor activity. Cost-effective and quality-assured.

NBDHEX is a potent inhibitor of glutathione S-transferase P1-1 (GSTP1-1).

Belimumab, a human IgG1λ monoclonal antibody, blocks BAFF, treating lupus and related fatigue.

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Simian sCD40L. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Simian sCD40L. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Simian sCD40L, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Simian sCD40L in the samples is then determined by comparing the OD of the samples to the standard curve.

Cusatuzumab (ARGX-110) is a human CD70 monoclonal antibody with enhanced antibody-dependent cytotoxic activity.

Ozoralizumab (ATN-103) is a humanized anti-TNFα antibody and a novel TNFα inhibitor.

NVP-2 selectively inhibits CDK9 (IC50: 0.514 nM), prompts apoptosis, and affects other CDKs (IC50: 0.584-0.706 μM).

BETd-260, a PROTAC linked by a Cereblon ligand and a BET ligand, has an inhibitory effect on BRD4 protein in leukemic cell lines.

C16 Ceramide (Palmitoyl Ceramide) is a naturally occurring small molecule that activates p53 by directly and selectively binding to it.

Tolperisone hydrochloride (Muscalm) is a muscle relaxant for treating muscle tone disorders from neurological diseases.

Tegaserod (SDZ-HTF-919), a 5-HT4 agonist for irritable bowel syndrome, was withdrawn by FDA on March 30, 2007, due to heart risk concerns.

Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.

Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property.

WJ-39 is an AR inhibitor that may be used to ameliorate renal insufficiency and fibrosis.

Tea polyphenol, also called green tea extract, are a mixture of chemical compounds, such as flavanoids and tannins, found naturally in tea.

Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.

Chlorzoxazone (Chlorzoxazon) is a Muscle Relaxant. The physiologic effect of chlorzoxazone is by means of Centrally-mediated Muscle Relaxation.

Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.

Minocycline HCl: tetracycline antibiotic, treats bacterial infections and acne, may cause acute or chronic hepatitis.

Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).

VTP50469 is a highly selective and orally active small molecule inhibitor of the Menin-MLL protein-protein interaction.Cost-effective and quality-assured.

IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.

Quiflapon (MK-591) is a potent, selective FLAP inhibitor (IC50: 1.6 nM) and oral LT biosynthesis blocker in humans and rats (IC50: 3.1/6.1 nM).

ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.

Stachyose tetrahydrate (D-Stachyose tetrahydrate) is a tetrasaccharide consisting of two α-D-galactose units, one α-D-glucose unit, and one β-D-fructose unit

BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect

Thiamine hydrochloride (Vitamin B1) is an essential micronutrient and a cofactor for many central metabolic enzymes. High-Quality, Low-Cost!

NCX 4016, a NO-donor nitro-derivative of Aspirin, inhibits COX-1 and triggers apoptosis in ovarian cancer cells by modulating EGFR/PI3K/STAT3 and Bcl-2.

Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα).

Ulocuplumab is a human anti-CXCR4 IgG4 antibody tackling AML, NHL, and multiple myeloma; induces CLL apoptosis.

Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Simian FAS. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Simian FAS. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Simian FAS, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Simian FAS in the samples is then determined by comparing the OD of the samples to the standard curve.

Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.

Enavatuzumab (PDL192) is a humanized monoclonal antibody targeting TWEAK receptor with anti-tumor activity.

Adarotene (ST1926) induces apoptosis, causes DNA damage, and has strong antiproliferative effects on human tumors.

Sotevtamab (AB-16B5) is a monoclonal antibody targeting clusterin, an inhibitor of epithelial-mesenchymal transition, with anticancer activity.

Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.

Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).