Apoptosi
Gli inibitori dell'apoptosi sono composti che prevengono o ritardano il processo di morte cellulare programmata, noto come apoptosi. Questi inibitori sono fondamentali per lo studio dei meccanismi di sopravvivenza cellulare e vengono utilizzati per indagare sulle malattie in cui l'apoptosi è disregolata, come il cancro, i disturbi neurodegenerativi e le malattie autoimmuni. Modulando l'apoptosi, questi inibitori possono aiutare nello sviluppo di terapie mirate a controllare la morte cellulare. Presso CymitQuimica, offriamo una vasta selezione di inibitori dell'apoptosi di alta qualità per supportare le tue ricerche in biologia cellulare, oncologia e campi correlati.
Sottocategorie di "Apoptosi"
- ASK(9 prodotti)
- BCL(11 prodotti)
- Caspasi(142 prodotti)
- FOXO1(3 prodotti)
- IAP(67 prodotti)
- Mdm2(12 prodotti)
- PD-1/PD-L1(138 prodotti)
- PDK(9 prodotti)
- PERK(25 prodotti)
- Chinasi di serina/treonina(14 prodotti)
- Survivin(14 prodotti)
- TNF(89 prodotti)
- c-RET(56 prodotti)
- p53(63 prodotti)
Mostrare 6 più sottocategorie
Trovati 5903 prodotti di "Apoptosi"
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Gemcitabine hydrochloride
CAS:Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.Formula:C9H11F2N3O4·HClPurezza:99.28% - 99.98%Colore e forma:White Crystalline Granular OdorlessPeso molecolare:299.66AEE788
CAS:<p>AEE788 (NVP-AEE 788) has been used in trials studying the treatment of Cancer, Glioblastoma Multiforme, and Brain and Central Nervous System Tumors.</p>Formula:C27H32N6Purezza:98% - >99.99%Colore e forma:SolidPeso molecolare:440.58Antineoplaston A10
CAS:Antineoplaston A10 (NSC-648539) is a Ras inhibitor potentially for the treatment of glioma, lymphoma, astrocytoma and breast cancer.Formula:C13H14N2O3Purezza:99.42%Colore e forma:SolidPeso molecolare:246.26Valepotriate
CAS:Valepotriates are sedative, enhance memory, have anti-cancer properties, and may reduce anxiety.Formula:C22H30O8Purezza:97.29% - 99.90%Colore e forma:SolidPeso molecolare:422.47(E)-Flavokawain A
CAS:(E)-Flavokawain A, a novel chalcone from kava extract, induces apoptosis by involvement of Bax protein-dependent and mitochondria-dependent apoptotic pathway.Formula:C18H18O5Purezza:98% - 99.75%Colore e forma:SolidPeso molecolare:314.33Oleuropein
CAS:Oleuropein is an antioxidant polyphenol isolated from olive leaf.Formula:C25H32O13Purezza:98% - 99.95%Colore e forma:Brown PowderPeso molecolare:540.51Columbianadin
CAS:Columbianadin (Zosimin), one of the main bioactive constituents of the roots of Angelica pubescens Maxim.Formula:C19H20O5Purezza:98.44% - 99.48%Colore e forma:SolidPeso molecolare:328.36Flavokawain C
CAS:<p>Flavokawain C: natural chalcone from Kava with potential as a colon cancer drug.</p>Formula:C17H16O5Purezza:99.94% - ≥95%Colore e forma:SolidPeso molecolare:300.31PK11007
CAS:PK11007 is an anti-p53 drug.Formula:C15H11ClFN5O3S2Purezza:97.55%Colore e forma:SolidPeso molecolare:427.86Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Formula:C29H34N6O4S2Purezza:97.67% - 98.44%Colore e forma:SolidPeso molecolare:594.75Neogambogic acid
CAS:<p>Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect.</p>Formula:C38H46O9Purezza:97.74% - 99.38%Colore e forma:SolidPeso molecolare:646.77SB 415286
CAS:SB 415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.Formula:C16H10ClN3O5Purezza:99.55%Colore e forma:SolidPeso molecolare:359.72UC2288
CAS:<p>UC2288, a Sorafenib-based p21 attenuator, reduces p21 levels without affecting its stability.</p>Formula:C20H18ClF6N3O2Purezza:99.75%Colore e forma:SolidPeso molecolare:481.82dBET6
CAS:<p>dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.</p>Formula:C42H45ClN8O7SPurezza:97.57% - 99.12%Colore e forma:SolidPeso molecolare:841.37Carnosic acid
CAS:Carnosic acid is a lipid absorption inhibitor, endowed with antioxidative, antimicrobial, photoprotective potential, and antiproliferative properties.Formula:C20H28O4Purezza:98.31% - 99.5%Colore e forma:Yellow PowderPeso molecolare:332.43MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Formula:C26H41N3O5Purezza:95% - 99.99%Colore e forma:White To Off-White PowderPeso molecolare:475.62Taurodeoxycholic acid sodium hydrate
CAS:<p>Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.</p>Formula:C26H46NNaO7SPurezza:99.95%Colore e forma:SolidPeso molecolare:539.70Triglycidyl isocyanurate
CAS:<p>Triglycidyl isocyanurate (Teroxirone) is a cancer-research chemical with DNA-altering properties, also used in metal finishing.</p>Formula:C12H15N3O6Purezza:99.01%Colore e forma:White Solid ParticulatesPeso molecolare:297.26PFI-90
CAS:PFI-90, a selective histone demethylase (KDM3B) inhibitor, targets PAX3-FOXO1 action and demonstrates potential antitumor activity.Formula:C11H10N4OPurezza:99.46%Colore e forma:SolidPeso molecolare:214.22Triptonide
CAS:<p>Triptonide treats autoimmune diseases, has antileukemic/tumor effects, is anti-inflammatory, and boosts IL-37.</p>Formula:C20H22O6Purezza:99.11% - 99.64%Colore e forma:White Crystalline PowderPeso molecolare:358.39Abacavir sulfate
CAS:Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activityFormula:C14H18N6OH2O4SPurezza:99.79% - 99.85%Colore e forma:White To Off-White SolidPeso molecolare:335.38Prucalopride Succinate
CAS:Prucalopride Succinate is a 5-HT4 receptor agonist with Ki 2.5 nM (5-HT4a) and 8 nM (5-HT4b).Formula:C18H26ClN3O3·C4H6O4Purezza:99.24%Colore e forma:SolidPeso molecolare:485.964-Methyldaphnetin
CAS:4-Methyldaphnetin (DHMC) is a potent inhibitor of lipid peroxidation and scavengers of superoxide anion radicals and of aqueous alkylperoxyl radicals.Formula:C10H8O4Purezza:99.73%Colore e forma:SolidPeso molecolare:192.17Brevilin A
CAS:Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.Formula:C20H26O5Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:346.42Methotrexate disodium
CAS:<p>Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor</p>Formula:C20H20N8Na2O5Purezza:99.77% - 99.96%Colore e forma:SolidPeso molecolare:498.4UCF 101
CAS:UCF 101 is a specific inhibitor of HtrA2 and reduces apoptosis in PC12 cells.Formula:C27H17N3O5SPurezza:99.64%Colore e forma:SolidPeso molecolare:495.51Gomisin N
CAS:Gomisin N from Schisandra chinensis offers sedative effects, allergy relief, and cancer cell inhibition/apoptosis.Formula:C23H28O6Purezza:99.97% - >99.99%Colore e forma:SolidPeso molecolare:400.46Verbascoside
CAS:Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.Formula:C29H36O15Purezza:97.46% - 99.55%Colore e forma:SolidPeso molecolare:624.59CAY10404
CAS:<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Formula:C17H12F3NO3SPurezza:99.02%Colore e forma:SolidPeso molecolare:367.34Picroside II
CAS:Picroside II (Vanilloyl catalpol) is the main active ingredient in iridoid glycosides.Formula:C23H28O13Purezza:98% - 99.83%Colore e forma:SolidPeso molecolare:512.46Desmethylanethol trithione
CAS:<p>Desmethylanethol trithione (ADT-OH), a synthetic H2S donor, modulates tPA effects, reduces stroke damage, and improves recovery in mice.</p>Formula:C9H6OS3Purezza:98.05% - 98.41%Colore e forma:SolidPeso molecolare:226.34ONC212
CAS:ONC212, a fluorinated-ONC201 analogue, is a selective agonist of GPR132.Formula:C24H23F3N4OPurezza:99.79%Colore e forma:SolidPeso molecolare:440.46GS-444217
CAS:GS-444217 is a selective ATP-competitive inhibitor of apoptosis signal-regulating kinase 1 (ASK1, IC50: 2.87 nM).Formula:C23H21N7OPurezza:99.08%Colore e forma:SolidPeso molecolare:411.46OUL35
CAS:OUL35 (NSC-39047) is a selective PARP-10 inhibitor, and small-molecule ARTD10 inhibitor. OUL35 has been shown to rescue cells from ARTD10-induced cell death.Formula:C14H12N2O3Purezza:99.2%Colore e forma:SolidPeso molecolare:256.26TCPOBOP
CAS:TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly.Formula:C16H8Cl4N2O2Purezza:99.7%Colore e forma:SolidPeso molecolare:402.06B355252
CAS:B355252 prevents glutamate-induced cell death and boosts NGF's nerve growth effects.Formula:C25H24ClN3O3S2Purezza:98.73% - 99.92%Colore e forma:SolidPeso molecolare:514.06Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFormula:C16H12O5Purezza:96.26% - ≥95%Colore e forma:Pale-Yellow NeedlesPeso molecolare:284.26VK3-OCH3
CAS:VK3-OCH3 (2-[(2-Methoxy)ethylthio]-3-methyl-1,4-na) is a selective antitumor agent via heme oxygenase (HO-1) related mechanisms; Vitamine K3 analogue.Formula:C14H14O3SPurezza:99.71%Colore e forma:SolidPeso molecolare:262.32CAY10505
CAS:CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Formula:C14H8FNO3SPurezza:99.69% - 99.74%Colore e forma:SolidPeso molecolare:289.28MRS 2578
CAS:MRS2578, an effective P2Y6 receptor antagonist with IC50 of 37 nM, shows insignificant inhibition at P2Y1, P2Y2, P2Y4, and P2Y11 receptors.Formula:C20H20N6S4Purezza:97.58% - 99.73%Colore e forma:White SolidPeso molecolare:472.67Polyphyllin I
CAS:<p>Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,</p>Formula:C44H70O16Purezza:98% - 99.5%Colore e forma:SolidPeso molecolare:855.02Epothilone A
CAS:Epothilone A (Epo A) is a microtubule-stabilizing agent with EC0.01 of 2 μM.Formula:C26H39NO6SPurezza:99.89% - 99.92%Colore e forma:SolidPeso molecolare:493.66Fedratinib hydrochloride hydrate
CAS:Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.Formula:C27H40Cl2N6O4SPurezza:98.96% - 99.87%Colore e forma:SolidPeso molecolare:615.61G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Formula:C22H19F2NO3Purezza:97.3%Colore e forma:SolidPeso molecolare:383.39OTS514 hydrochloride
CAS:OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).Formula:C21H20N2O2S·HClPurezza:99.67% - 99.84%Colore e forma:SolidPeso molecolare:400.92Kynurenic acid sodium
CAS:Kynurenic acid sodium salt is an endogenous tryptophan metabolite. It antagonizes NMDA, glutamate, and α7 nicotinic receptors, and agonizes GPR35.Formula:C10H6NNaO3Purezza:99.47%Colore e forma:SolidPeso molecolare:211.15Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Formula:C15H18O3Purezza:98.48% - 99.96%Colore e forma:SolidPeso molecolare:246.3CASIN
CAS:CASIN (Pirl1-related Compound 2) is a specific inhibitor of GTPase Cdc42 (IC50: 2 uM).Formula:C20H22N2OPurezza:98.18% - >99.99%Colore e forma:SolidPeso molecolare:306.4NU 7026
CAS:NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibitionFormula:C17H15NO3Purezza:99.51% - >99.99%Colore e forma:SolidPeso molecolare:281.314EGI-1
CAS:4EGI-1, a competitive eIF4E/eIF4 g interaction inhibitor, binds to eIF4E(KD=25 μM).Formula:C18H12Cl2N4O4SPurezza:96.8% - 99.12%Colore e forma:SolidPeso molecolare:451.28
